-
公开(公告)号：US20160318935A1
公开(公告)日：2016-11-03
申请号：US15103756
申请日：2014-12-11
Applicant: BIOGEN MA INC. , SUNESIS PHARMACEUTICALS, INC.
Inventor： Brian T. Hopkins , Bin Ma , Timothy Raymond Chan , Gnanasambandam Kumaravel , Hua Miao , Andrea Bertolotti-Ciarlet , Kevin Otipoby
IPC: C07D487/04 , G01N33/573 , C07D513/04 , C07D473/00 , C07D519/00 , C07D471/04
CPC classification number: C07D487/04 , C07D471/04 , C07D473/00 , C07D513/04 , C07D519/00 , G01N33/573 , G01N2333/9121
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
Abstract translation: 本发明提供了可用作Bruton酪氨酸激酶抑制剂的化合物及其组合物，其表现出所需特性。
-
公开(公告)号：US20160311802A1
公开(公告)日：2016-10-27
申请号：US15103749
申请日：2014-12-11
Applicant: Biogen MA Inc. , Sunesis Pharmaceuticals, Inc.
Inventor： Brian T. Hopkins , Bin Ma , Timothy Raymond Chan , Lihong Sun , Lei Zhang , Gnanasambandam Kumaravel , Joseph P. Lyssikatos , Kevin Koch , Hua Miao
IPC: C07D403/12 , C07D495/04 , C07D409/14 , C07D487/04 , C07D513/04 , C07D413/14 , C07D417/12 , C07D417/14 , C07D401/14
CPC classification number: C07D403/12 , A61K31/506 , C07D239/30 , C07D401/14 , C07D409/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/04 , C07D495/04 , C07D513/04 , C07F5/027
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
Abstract translation: 本发明提供了可用作Bruton酪氨酸激酶抑制剂的化合物及其组合物，并且其表现出所需特性。
-
公开(公告)号：US20160039825A1
公开(公告)日：2016-02-11
申请号：US14772481
申请日：2014-03-14
Applicant: BIOGEN MA INC.
Inventor： Hairuo Peng , Zhili Xin , Lei Zhang , Lihong Sun , Gnanasambandam Kumaravel , Art Taveras , Deping Wang
IPC: C07D487/04 , C07D519/00
CPC classification number: A61K31/198 , A61K36/9068 , C07D487/04 , C07D519/00
Abstract: Compounds of formula (I), and pharmaceutically acceptable salts thereof, can modulate the activity of one or more SIP receptors and/or the activity of autotaxin (ATX).
-
公开(公告)号：US20220332705A1
公开(公告)日：2022-10-20
申请号：US17004411
申请日：2020-08-27
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Timothy Raymond Chan , Lihong Sun , Lei Zhang , Gnanasambandam Kumaravel , Joseph P. Lyssikatos , Kevin Koch , Hua Miao
IPC: C07D403/12 , A61K31/506 , C07D239/30 , C07F5/02 , C07D401/14 , C07D413/14 , C07D409/14 , C07D417/12 , C07D417/14 , C07D495/04 , C07D513/04 , C07D487/04
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
-
公开(公告)号：US10894040B2
公开(公告)日：2021-01-19
申请号：US16542746
申请日：2019-08-16
Applicant: BIOGEN MA INC.
Inventor： Jermaine Thomas , Sha Mi , Edward Yin-Shiang Lin , Guo Zhu Zheng , Bin Ma , Richard D. Caldwell , Kevin Guckian , Gnanasambandam Kumaravel
IPC: A61K31/445 , C07D211/34 , C07D211/60 , C07D211/62 , C07D405/12 , C07D401/06 , C07D215/20 , A61K31/225 , A61K31/4545 , A61K31/4709 , A61K31/498 , A61K31/517 , A61K31/55 , A61K31/695 , A61K38/21 , A61K39/395 , C07K16/28
Abstract: The present invention provides compounds of formula (I) or (II) or a pharmaceutically acceptable salt thereof and their use in modulating the activity of S1P) receptors. Also provided is a pharmaceutical composition comprising the compounds of formula (I) or (II) or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable excipient or carrier.
-
Patent Agency Ranking
公开(公告)号：US10759783B2
公开(公告)日：2020-09-01
申请号：US16108755
申请日：2018-08-22
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Timothy Raymond Chan , Lihong Sun , Lei Zhang , Gnanasambandam Kumaravel , Joseph P. Lyssikatos , Kevin Koch , Hua Miao
IPC: C07D403/12 , C07D417/14 , C07D495/04 , C07D409/14 , C07D401/14 , C07D513/04 , C07D413/14 , A61K31/506 , C07D239/30 , C07F5/02 , C07D417/12 , C07D487/04
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
-
公开(公告)号：US20190248787A1
公开(公告)日：2019-08-15
申请号：US16271497
申请日：2019-02-08
Applicant: BIOGEN MA INC.
Inventor： Timothy Chan , Kevin Guckian , Tracy Jenkins , Jermaine Thomas , Jeffery Vessels , Gnanasambandam Kumaravel , Robert Meissner , Joseph Lyssikatos , Brian Lucas , Irina Leaf , Jeremy Duffield
IPC: C07D471/04 , C07D417/14 , C07D413/14 , A61K31/416 , C07D401/12 , C07B59/00 , C07D405/14 , C07D401/14
Abstract: Provided are compounds of Formula I, or pharmaceutically acceptable salts thereof, and methods for their use and production.
-
公开(公告)号：US20190209592A1
公开(公告)日：2019-07-11
申请号：US16182845
申请日：2018-11-07
Applicant: BIOGEN MA INC.
Inventor： Jermaine Thomas , Xiaogao Liu , Edward Yin-Shiang Lin , Guo Zhu Zheng , Bin Ma , Richard D. Caldwell , Kevin M. Guckian , Gnanasambandam Kumaravel , Arthur G. Taveras
IPC: A61K31/695 , A61K31/11 , C07F7/08 , A61K31/165 , A61K31/137 , A61K31/235 , A61K31/223 , C07D401/06 , C07D277/64 , C07D239/74 , C07D217/04 , C07D215/227 , C07C255/54 , C07C47/575 , C07C43/247 , A61K45/06 , A61K31/683 , A61K31/662 , A61K31/517 , A61K31/472 , A61K31/4709 , A61K31/47 , A61K31/445 , A61K31/428 , A61K31/41 , A61K31/404 , A61K31/40 , A61K31/397 , A61K31/337 , A61K31/277 , A61K31/216 , A61K31/197 , A61K31/18 , C07F9/38 , A61K31/085 , C07F9/40 , C07D417/06 , C07D403/06 , C07D305/08 , C07D257/04 , C07D217/24 , C07D215/20 , C07D211/62 , C07D211/60 , C07D209/08 , C07D207/16 , C07D205/04 , C07C311/51 , C07C309/14 , C07C237/52 , C07C237/08 , C07C229/48 , C07C229/46 , C07C229/22 , C07C229/14 , A61K31/401 , A61K31/185 , A61K31/198 , A61K31/222
CPC classification number: A61K31/695 , A61K31/085 , A61K31/11 , A61K31/137 , A61K31/165 , A61K31/18 , A61K31/185 , A61K31/197 , A61K31/198 , A61K31/216 , A61K31/222 , A61K31/223 , A61K31/235 , A61K31/277 , A61K31/337 , A61K31/397 , A61K31/40 , A61K31/401 , A61K31/404 , A61K31/41 , A61K31/428 , A61K31/445 , A61K31/47 , A61K31/4709 , A61K31/472 , A61K31/517 , A61K31/662 , A61K31/683 , A61K45/06 , C07C43/247 , C07C47/575 , C07C229/14 , C07C229/22 , C07C229/46 , C07C229/48 , C07C237/08 , C07C237/52 , C07C255/54 , C07C309/14 , C07C311/51 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07D205/04 , C07D207/16 , C07D209/08 , C07D211/60 , C07D211/62 , C07D215/20 , C07D215/227 , C07D217/04 , C07D217/24 , C07D239/74 , C07D257/04 , C07D277/64 , C07D305/08 , C07D401/06 , C07D403/06 , C07D417/06 , C07F7/081 , C07F9/3808 , C07F9/3834 , C07F9/4006
Abstract: Compounds that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at S1P receptors.
-
公开(公告)号：US10280169B2
公开(公告)日：2019-05-07
申请号：US15103756
申请日：2014-12-11
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Timothy Raymond Chan , Gnanasambandam Kumaravel , Hua Miao , Andrea Bertolotti-Ciarlet , Kevin Otipoby
IPC: C07D487/04 , C07D473/00 , A61K31/519 , A61K31/522 , C07D471/04 , C07D513/04 , C07D519/00 , G01N33/573
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
-
公开(公告)号：US10246456B2
公开(公告)日：2019-04-02
申请号：US15326740
申请日：2015-07-17
Applicant: BIOGEN MA INC.
Inventor： Timothy Chan , Kevin Guckian , Tracy Jenkins , Jermaine Thomas , Jeffery Vessels , Gnanasambandam Kumaravel , Robert Meissner , Joseph Lyssikatos , Brian Lucas , Irina Leaf , Jeremy Duffield
IPC: C07D471/04 , C07D413/14 , C07D405/14 , C07D401/14 , A61K31/416 , A61P13/12 , C07B59/00 , C07D401/12 , C07D417/14
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
-
-
-
-
-
-
-
-
-
Search Results
53
records
(took 0.044 seconds)
