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53 条记录 (耗时 0.034 秒)

    Acquiring nerve activity from carotid body and/or sinus
    32.
    发明授权
    Acquiring nerve activity from carotid body and/or sinus 有权
    从颈动脉体和/或窦获得神经活动

    公开(公告)号：US07953479B2

    公开(公告)日：2011-05-31

    申请号：US12833170

    申请日：2010-07-09

    申请人： Brian Jeffrey Wenzel ,  Taraneh Ghaffari Farazi

    发明人： Brian Jeffrey Wenzel ,  Taraneh Ghaffari Farazi

    IPC分类号： A61N1/08

    CPC分类号： A61N1/36114 ,  A61B5/04001 ,  A61B5/4047 ,  A61B5/7264 ,  A61N1/36117 ,  A61N1/36514 ,  A61N1/36557 ,  A61N1/36564

    摘要： An exemplary includes acquiring an electroneurogram of the right carotid sinus nerve or the left carotid sinus nerve, analyzing the electroneurogram for at least one of chemosensory information and barosensory information and calling for one or more therapeutic actions based at least in part on the analyzing. Therapeutic actions may aim to treat conditions such as sleep apnea, an increase in metabolic demand, hypoglycemia, hypertension, renal failure, and congestive heart failure. Other exemplary methods, devices, systems, etc., are also disclosed.

    摘要翻译： 示例性的包括获取右颈动脉窦神经或左颈动脉窦神经的电子图，分析至少一个化学感觉信息和感知信息的电子图，并至少部分地基于分析来呼叫一个或多个治疗动作。 治疗作用可能旨在治疗诸如睡眠呼吸暂停，代谢需求增加，低血糖症，高血压，肾衰竭和充血性心力衰竭等病症。 还公开了其它示例性方法，装置，系统等。

    ACQUIRING NERVE ACTIVITY FROM CAROTID BODY AND/OR SINUS
    33.
    发明申请
    ACQUIRING NERVE ACTIVITY FROM CAROTID BODY AND/OR SINUS 有权
    从卡罗维达和/或SINUS获得神经活动

    公开(公告)号：US20110046508A1

    公开(公告)日：2011-02-24

    申请号：US12915991

    申请日：2010-10-29

    申请人： Brian Jeffrey Wenzel ,  Taraneh Ghaffari Farazi

    发明人： Brian Jeffrey Wenzel ,  Taraneh Ghaffari Farazi

    IPC分类号： A61B5/053

    CPC分类号： A61N1/36114 ,  A61B5/04001 ,  A61B5/4047 ,  A61B5/7264 ,  A61N1/36117 ,  A61N1/36514 ,  A61N1/36557 ,  A61N1/36564

    摘要： An exemplary includes acquiring an electroneurogram of the right carotid sinus nerve or the left carotid sinus nerve, analyzing the electroneurogram for at least one of chemosensory information and barosensory information and calling for one or more therapeutic actions based at least in part on the analyzing. Therapeutic actions may aim to treat conditions such as sleep apnea, an increase in metabolic demand, hypoglycemia, hypertension, renal failure, and congestive heart failure. Other exemplary methods, devices, systems, etc., are also disclosed.

    摘要翻译： 示例性的包括获取右颈动脉窦神经或左颈动脉窦神经的电子图，分析至少一个化学感觉信息和感知信息的电子图，并至少部分地基于分析来呼叫一个或多个治疗动作。 治疗作用可能旨在治疗诸如睡眠呼吸暂停，代谢需求增加，低血糖症，高血压，肾衰竭和充血性心力衰竭等病症。 还公开了其它示例性方法，装置，系统等。

    System and method for detecting hypoglycemia using an implantable medical device based on pre-symptomatic physiological responses
    35.
    发明授权
    System and method for detecting hypoglycemia using an implantable medical device based on pre-symptomatic physiological responses 有权
    基于预处理的生理反应，使用可植入医疗装置检测低血糖的系统和方法

    公开(公告)号：US08019410B1

    公开(公告)日：2011-09-13

    申请号：US11843480

    申请日：2007-08-22

    申请人： Rupinder Bharmi ,  Gene A. Bornzin ,  Brian Jeffrey Wenzel

    发明人： Rupinder Bharmi ,  Gene A. Bornzin ,  Brian Jeffrey Wenzel

    IPC分类号： A61B5/0205 ,  A61B5/0452

    CPC分类号： A61B5/0205 ,  A61B5/0472 ,  A61B5/721

    摘要： An intracardiac electrogram (IEGM) or other suitable electrical cardiac signal is sensed. Values representative of a pre-symptomatic physiologic response to a hypoglycemic event are derived from the cardiac signal. Then, hypoglycemia is detected based on the values representative of the pre-symptomatic physiologic response. In one example, both temporal morphological parameters and spectral parameters affected by pre-symptomatic hypoglycemia are derived from the cardiac signal. Hypoglycemia is then detected based on a combination of the temporal and spectral parameters using, e.g., a linear discriminator. By detecting hypoglycemia based on parameters affected by pre-symptomatic hypoglycemia, suitable warnings can be generated and therapies initiated before the condition becomes symptomatic.

    摘要翻译： 感测到心内电描记图（IEGM）或其他合适的心电信号。 代表低血糖事件的症状性生理反应的值代表心脏信号。 然后，根据代表症状前生理反应的值检测低血糖。 在一个实例中，由症状性低血糖影响的时间形态学参数和光谱参数均来自心脏信号。 然后使用例如线性鉴别器基于时间和频谱参数的组合检测低血糖。 通过根据受症状性低血糖影响的参数检测低血糖，可以产生合适的警告，并在症状发作前进行治疗。

    System and method for estimating electrical conduction delays from immittance values measured using an implantable medical device
    37.
    发明授权
    System and method for estimating electrical conduction delays from immittance values measured using an implantable medical device 有权
    用于使用可植入医疗装置测量的导纳值估计导电延迟的系统和方法

    公开(公告)号：US08208999B2

    公开(公告)日：2012-06-26

    申请号：US12127963

    申请日：2008-05-28

    申请人： Brian Jeffrey Wenzel ,  Dorin Panescu ,  Mihir Naware ,  Jeffery Siou

    发明人： Brian Jeffrey Wenzel ,  Dorin Panescu ,  Mihir Naware ,  Jeffery Siou

    IPC分类号： A61B5/04

    CPC分类号： A61B5/0215 ,  A61B5/0002 ,  A61B5/002 ,  A61B5/053 ,  A61B5/4839 ,  A61B5/686 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/7405 ,  A61B5/742 ,  A61B5/746 ,  A61B2560/0223 ,  A61N1/36521

    摘要： Techniques are provided for estimating electrical conduction delays with the heart of a patient based on measured immittance values. In one example, impedance or admittance values are measured within the heart of a patient by a pacemaker or other implantable medical device, then used by the device to estimate cardiac electrical conduction delays. A first set of predetermined conversion factors may be used to convert the measured immittance values into conduction delay values. In some examples, the device then uses the estimated conduction delay values to estimate LAP or other cardiac pressure values. A second set of predetermined conversion factors may be used to convert the estimated conduction delays into pressure values. Techniques are also described for adaptively adjusting pacing parameters based on estimated LAP.

    摘要翻译： 提供了用于基于测量的导纳值估计与患者心脏的导电延迟的技术。 在一个示例中，阻抗或导纳值由起搏器或其他可植入医疗装置在患者的心脏内测量，然后由装置用于估计心脏导电延迟。 可以使用第一组预定转换因子将测量的导纳值转换为导通延迟值。 在一些示例中，器件然后使用估计的传导延迟值来估计LAP或其他心脏压力值。 可以使用第二组预定转换因子将估计的传导延迟转换为压力值。 还描述了基于估计的LAP自适应地调整起搏参数的技术。

    Method and system to correct contractility based on non-heart failure factors
    40.
    发明授权
    Method and system to correct contractility based on non-heart failure factors 有权
    基于非心力衰竭因子校正收缩性的方法和系统

    公开(公告)号：US08843197B2

    公开(公告)日：2014-09-23

    申请号：US13049774

    申请日：2011-03-16

    申请人： Stuart Rosenberg ,  Cecilia Qin Xi ,  Jong Gill ,  Brian Jeffrey Wenzel ,  Yelena Nabutovsky ,  William Hsu

    发明人： Stuart Rosenberg ,  Cecilia Qin Xi ,  Jong Gill ,  Brian Jeffrey Wenzel ,  Yelena Nabutovsky ,  William Hsu

    IPC分类号： A61N1/365 ,  A61B5/02 ,  A61B5/042 ,  A61N1/362

    CPC分类号： A61N1/36585 ,  A61B5/02028 ,  A61B5/042 ,  A61N1/3627 ,  A61N1/36507 ,  A61N1/36521 ,  A61N1/36564 ,  A61N1/36578

    摘要： A method for trending heart failure measures cardiogenic impedance (CI) and obtains signals representing estimates for or direct measurements of at least one of cardiac volume and pressure of the heart when the CI measurements were obtained. The method identifies correction factors based on the signals and applies the correction factors to the contractility estimates. A system for trending heart failure includes a contractility module to determine contractility estimates from CI measurements taken along at least a first vector through a heart, and a collection module to receive signals representing estimates for or direct measurements of at least one of cardiac volume and pressure of the heart when the CI measurements were obtained. The system further includes a factor module to identify correction factors based on the signals and a correction module to apply the correction factors to the contractility estimates.

    摘要翻译： 用于趋势性心力衰竭的方法测量心源性阻抗（CI）并且获得当获得CI测量时表示心脏体积和心脏压力中的至少一个的估计或直接测量的信号。 该方法基于信号识别校正因子，并将修正因子应用于收缩率估计。 用于趋向心力衰竭的系统包括收缩模块，用于根据通过心脏的至少第一载体进行的CI测量来确定收缩性估计，以及收集模块，用于接收代表心脏体积和压力中的至少一个的估计或直接测量的信号 的CI测量值。 该系统还包括一个因素模块，用于基于信号识别校正因子，以及一个校正模块，以将校正因子应用于收缩性估计。