公开(公告)号：US20100108872A1

公开(公告)日：2010-05-06

申请号：US12285958

申请日：2008-10-17

申请人： Cheng-Hsien Liu ,  William Wang ,  Long Hsu ,  Chung-Cheng Chou ,  Sheng-Yang Tseng ,  Chen Peng ,  Fung-Hsu Wu ,  Ta-Yuan Lee

发明人： Cheng-Hsien Liu ,  William Wang ,  Long Hsu ,  Chung-Cheng Chou ,  Sheng-Yang Tseng ,  Chen Peng ,  Fung-Hsu Wu ,  Ta-Yuan Lee

IPC分类号： H05H3/00 ,  C25B9/16

CPC分类号： B03C5/026 ,  G01N35/10 ,  G01N2035/1046

摘要： An optical tweezers lifting apparatus is provided. The optical tweezers lifting apparatus includes an optical tweezers and a particle-lifting device. The particle-lifting device includes a substrate and a plurality of electrodes that are disposed on the bottom of a flow path in the substrate. When a dielectrophoresis (DEP) solution with a plurality of floating particles is conducted into the flow path and upon those electrodes and a voltage is applied to these electrodes, these particles would be driven by a negative DEP force to move upward to a specific depth in the flow path. Meanwhile, the optical tweezers of the apparatus is selectively focused at the specific depth in the flow path.

公开(公告)号：US20090273831A1

公开(公告)日：2009-11-05

申请号：US12432876

申请日：2009-04-30

申请人： Long Hsu ,  Kuang-Lung Huang ,  William Wang ,  Cheng-Hsien Liu ,  Yuh-Shyong Yang ,  Che-Liang Tsai ,  Chung-Cheng Chou

发明人： Long Hsu ,  Kuang-Lung Huang ,  William Wang ,  Cheng-Hsien Liu ,  Yuh-Shyong Yang ,  Che-Liang Tsai ,  Chung-Cheng Chou

IPC分类号： G02B21/10 ,  H05H3/00

CPC分类号： G02B21/10 ,  G02B21/32

摘要： A light module is provided. The light module applied to a dark field microscope is used for illuminating an object. The light module includes a light beam, a reflection component and a condensing component. The light beam has several lights. The reflection component is used for converting the lights radiating along a beginning direction to a circular beam substantially radiating along the beginning direction. The circular beam passes through the condensing component and is focused on the object. A part of the circular beam passing through the condensing component is scattered by the object.

摘要翻译： 提供灯模块。 应用于暗视野显微镜的光模块用于照亮物体。 光模块包括光束，反射部件和冷凝部件。 光束有几个灯。 反射分量用于将沿开始方向辐射的光转换成沿着开始方向基本辐射的圆形光束。 圆形光束通过冷凝部件并聚焦在物体上。 通过聚光部件的圆形光束的一部分被物体散射。

公开(公告)号：US20090032692A1

公开(公告)日：2009-02-05

申请号：US12219871

申请日：2008-07-30

申请人： Long Hsu ,  Cheng-Hsien Liu ,  Sheng-Yang Tseng ,  William Wang ,  Chung-Cheng Chou ,  Fung-Hsu Wu ,  Chen Peng ,  Ta-Yuan Lee

发明人： Long Hsu ,  Cheng-Hsien Liu ,  Sheng-Yang Tseng ,  William Wang ,  Chung-Cheng Chou ,  Fung-Hsu Wu ,  Chen Peng ,  Ta-Yuan Lee

IPC分类号： H05H3/00 ,  G02B27/42

CPC分类号： G02B21/32 ,  Y10T436/25375

摘要： An apparatus of generating an optical tweezers with momentum and method thereof and an optical tweezers photo-image for guiding particles are provided. The apparatus generates at least one optical tweezers on an examined object that carries at least one particle. The apparatus includes a laser source, a diffractive optical element and a convergent lens. The laser beam from the laser source passes through the diffractive optical element to produce a diffractive pattern. The laser beam is then received by the convergent lens and then to be focused on a plane of the examined object. The optic axis of the convergent lens is substantially not perpendicular to the plane of the examined object, so that the laser beam is projected onto the plane of the examined object in a skewed manner for providing a lateral momentum to move the particle.

摘要翻译： 提供了一种用于产生具有动量及其方法的光学镊子的装置和用于引导颗粒的光学镊子照片。 该装置在携带至少一个颗粒的被检查物体上产生至少一个光学镊子。 该装置包括激光源，衍射光学元件和会聚透镜。 来自激光源的激光束通过衍射光学元件以产生衍射图案。 然后激光束被会聚透镜接收，然后被聚焦在被检查物体的平面上。 会聚透镜的光轴基本上不垂直于被检查物体的平面，使得激光束以倾斜的方式投射到被检查物体的平面上，以提供横向动量来移动颗粒。

公开(公告)号：US20080188160A1

公开(公告)日：2008-08-07

申请号：US12068069

申请日：2008-02-01

申请人： Chung-Cheng Chou ,  Wai Wang

发明人： Chung-Cheng Chou ,  Wai Wang

IPC分类号： A63H3/36

CPC分类号： A63H15/06 ,  A63H13/00

摘要： An interactive apparatus has a base and a motion unit. The base has a first curved surface with a concave facing. The motion unit is located on the first curved surface and has a second curved surface with a convex facing contacting the first curved surface. In addition, the second curved surface has a curvature greater than that of the first curved surface. As the motion unit is steady on the first curved surface, a gravity center of the motion unit is located below a curvature center of the second curved surface.

摘要翻译： 交互式装置具有基座和运动单元。 底座具有带凹面的第一曲面。 运动单元位于第一弯曲表面上，并且具有第二弯曲表面，凸面面向第一弯曲表面接触。 另外，第二曲面的曲率大于第一曲面的曲率。 当运动单元在第一弯曲表面上稳定时，运动单元的重心位于第二曲面的曲率中心的下方。

公开(公告)号：US20080174870A1

公开(公告)日：2008-07-24

申请号：US12019316

申请日：2008-01-24

申请人： Long Hsu ,  Cheng-Hsien Liu ,  Sheng-Yang Tseng ,  Chung-Cheng Chou ,  Wai William Wang ,  Fung-Hsu Wu ,  Chen Peng ,  Ta-Yuan Lee

发明人： Long Hsu ,  Cheng-Hsien Liu ,  Sheng-Yang Tseng ,  Chung-Cheng Chou ,  Wai William Wang ,  Fung-Hsu Wu ,  Chen Peng ,  Ta-Yuan Lee

IPC分类号： G02B27/42

CPC分类号： G02B21/32 ,  G02B5/1842 ,  G02B21/0088

摘要： An apparatus of generating optical tweezers with momentum is provided for providing optical tweezers with a first momentum on a test piece. The apparatus comprises a laser source, a diffractive optical element (DOE) and a lens. The laser source is for outputting a laser beam. The DOE has a first phase-delay picture, and the laser beam forms a diffraction pattern after passing the first phase-delay picture. The lens is for receiving and focusing the diffraction pattern on the test piece to form the first optical tweezers with the first momentum. The lens has an optical axis intersecting the DOE at an optical intersection point, a geometric center of the phase-delay picture has a displacement vector relative to the optical intersection point and a direction of the first momentum is related to a direction of the displacement vector.

摘要翻译： 提供产生具有动量的光学镊子的装置，用于在测试片上提供具有第一动量的光学镊子。 该装置包括激光源，衍射光学元件（DOE）和透镜。 激光源用于输出激光束。 DOE具有第一相位延迟图像，并且激光束在通过第一相位延迟图像之后形成衍射图案。 透镜用于接收和聚焦在测试片上的衍射图案以形成具有第一动量的第一光学镊子。 透镜在光学交点处具有与DOE相交的光轴，相位延迟图像的几何中心具有相对于光学交叉点的位移矢量，并且第一动量的方向与位移矢量的方向相关 。

公开(公告)号：US20080108121A1

公开(公告)日：2008-05-08

申请号：US11797418

申请日：2007-05-03

申请人： Cheng-Hsien Liu ,  Hwan-You Chang ,  Long Hsu ,  Chen-Ta Ho ,  Ruei-Zeng Lin ,  Wai William Wang ,  Ta-Yuan Lee ,  Chung-Cheng Chou ,  Chen Peng ,  Fung-Hsu Wu

发明人： Cheng-Hsien Liu ,  Hwan-You Chang ,  Long Hsu ,  Chen-Ta Ho ,  Ruei-Zeng Lin ,  Wai William Wang ,  Ta-Yuan Lee ,  Chung-Cheng Chou ,  Chen Peng ,  Fung-Hsu Wu

IPC分类号： C12N13/00 ,  C12M1/00

CPC分类号： C12N5/0697 ,  C12N5/067 ,  C12N2500/14 ,  C12N2500/16 ,  C12N2502/14 ,  C12N2502/28 ,  C12N2529/00 ,  C12N2535/10

摘要： A method of arranging cells comprises: (a) applying a voltage to two electrodes so as to allow a plurality of cells suspended in a dielectrophoresis-manipulating buffer (DEP-manipulating buffer) to be driven to be arranged into a pattern; (b) replacing the DEP-manipulating buffer with a solution comprising calcium ion and magnesium ion which helps the patterned cells adhere to the substrate; and (c) replacing the solution comprising calcium ion and magnesium ion with a medium so as to allow the patterned cells to grow on the substrate.

摘要翻译： 一种布置电池的方法包括：（a）向两个电极施加电压，以允许驱动悬浮在介电电泳操纵缓冲器（DEP-操纵缓冲器）中的多个电池被布置成图案; （b）用包含钙离子和镁离子的溶液代替DEP操纵缓冲液，其帮助图案化细胞粘附到基底上; 和（c）用培养基替换包含钙离子和镁离子的溶液，以使图案化细胞在基底上生长。

公开(公告)号：US20080067059A1

公开(公告)日：2008-03-20

申请号：US11830879

申请日：2007-07-31

申请人： Chung-Cheng Chou ,  Wai William Wang

发明人： Chung-Cheng Chou ,  Wai William Wang

IPC分类号： C25B9/00 ,  B07C5/08

CPC分类号： B07C5/08

摘要： A fluid particle-separating device includes a sorting, first and second diverting channels, a detector, a microprocessor, first and second actuators, and first and second sieving valves. The sorting channel receives fluid containing first and second particles. The first and second diverting channels guide the first and second particles. The detector recognizes the sizes and numbers of the first and second particles and outputs first and second recognition signals. The microprocessor receives the first and second recognition signals and outputs first and second control signals. The first and second sieving valves respectively inside the first and second diverting channels allow the particles to pass through or not. The first actuator receives the first control signal and controls the deformation of the second sieving valve to block the first particle. The second actuator receives the second control signal and controls the deformation of the first sieving valve to block the second particle.

摘要翻译： 流体颗粒分离装置包括分选，第一和第二转向通道，检测器，微处理器，第一和第二致动器以及第一和第二筛分阀。 分选通道接收含有第一和第二颗粒的​​流体。 第一和第二转向通道引导第一和第二颗粒。 检测器识别第一和第二颗粒的​​尺寸和数量，并输出第一和第二识别信号。 微处理器接收第一和第二识别信号并输出​​第一和第二控制信号。 分别在第一和第二转向通道内的第一和第二筛分阀允许颗粒通过或不通过。 第一致动器接收第一控制信号并且控制第二筛选阀的变形以阻挡第一粒子。 第二执行器接收第二控制信号并且控制第一筛分阀的变形以阻挡第二颗粒。

公开(公告)号：US20070120894A1

公开(公告)日：2007-05-31

申请号：US11563652

申请日：2006-11-27

申请人： Chung-Cheng Chou ,  Shang-Shi Wu

发明人： Chung-Cheng Chou ,  Shang-Shi Wu

IPC分类号： B41J2/05

CPC分类号： B41J2/14088 ,  B41J2/14056 ,  B41J2002/1437

摘要： Microinjectors are provided. A microinjector includes a substrate, a manifold formed on the substrate, and at least a jet unit. The jet unit includes a nozzle layer connected to the substrate, a nozzle disposed on the nozzle layer, a reservoir, a first heater disposed on a first side of the nozzle and a second heater disposed on a second side of the nozzle. The reservoir is formed between the nozzle layer and the substrate, connecting the nozzle and the manifold. Specifically, the first and second heaters are actuated by individual drive circuits, to heat the reservoir and eject a droplet through the nozzle.

摘要翻译： 提供微量注射器。 微型注射器包括基底，形成在基底上的歧管和至少一个喷射单元。 喷射单元包括连接到基板的喷嘴层，设置在喷嘴层上的喷嘴，储存器，设置在喷嘴的第一侧上的第一加热器和设置在喷嘴的第二侧上的第二加热器。 储存器形成在喷嘴层和基板之间，连接喷嘴和歧管。 具体地，第一和第二加热器由单独的驱动电路致动，以加热储存器并通过喷嘴喷射液滴。

公开(公告)号：US07224207B2

公开(公告)日：2007-05-29

申请号：US11231035

申请日：2005-09-20

申请人： Chung-Cheng Chou ,  Chien-Hua Huang

发明人： Chung-Cheng Chou ,  Chien-Hua Huang

IPC分类号： G05F1/10

CPC分类号： H02M3/07

摘要： A method and system is disclosed for an improved charge pump system. The system comprises one or more charge pump devices for providing an output voltage, a ring oscillator coupled with the charge pump devices for providing an oscillator output, and a multiple level detection device for detecting the output voltage and controlling the charge pump for stabilizing the output voltage.

公开(公告)号：US06967877B2

公开(公告)日：2005-11-22

申请号：US10658833

申请日：2003-09-09

申请人： Chung-Cheng Chou

发明人： Chung-Cheng Chou

IPC分类号： G11C11/406 ,  G11C7/00

CPC分类号： G11C11/40626 ,  G11C11/406 ,  G11C2211/4061

摘要： Systems for providing a temperature detecting circuit includes seven transistors and six resistors. In a preferred embodiment, one of the seven transistors is configured as an enabling element and the others form two comparators. The six resistors form three voltage dividers with output varying based upon changing temperature. Two comparators are included that sense the difference between the outputs of two of the voltage dividers, and generate a corresponding 2-bit detection signal by which the refresh period is determined. Other systems and methods are also provided.