公开(公告)号：US20240108458A1

公开(公告)日：2024-04-04

申请号：US18377966

申请日：2023-10-09

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Jeanette Jasmine Corona Kelly (formerly Corona) ,  Taylor Michael Winters ,  Ashley Akemi Ishigo ,  Lien Huong Thi Hoang ,  Gil Senesh ,  Vicky Hong Do ,  Quang Ngoc Vu ,  Kim D. Nguyen ,  Brendan Michael Dalbow

IPC: A61F2/24 ,  A61B50/30 ,  A61M25/10

CPC classification number: A61F2/24 ,  A61B50/30 ,  A61F2/2418 ,  A61F2/2436 ,  A61M25/10 ,  A61F2/2433 ,  A61F2/9517

Abstract: Methods and systems for attaching a radiopaque marker to a prosthetic heart valve to indicate a location of a commissure of the prosthetic heart valve are disclosed. As one example, a prosthetic heart valve includes a frame including a plurality of struts forming a plurality of cells of the frame arranged between an inflow end and an outflow end of the frame, a plurality of leaflets arranged within the frame, and at least one commissure comprising an attachment member arranged across a selected cell of the plurality of cells of the frame and commissure tabs of two adjacent leaflets coupled to the attachment member. The valve further includes a radiopaque marker arranged on the attachment member of the commissure within the selected cell.

公开(公告)号：US20240099844A1

公开(公告)日：2024-03-28

申请号：US18478083

申请日：2023-09-29

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Arvin T. Chang ,  Yair A. Neumann ,  Gil Senesh ,  Hernan Altman ,  Scott Louis Pool ,  Hannah Gibson ,  Amanda Kristine Anderson White ,  Peter Phong Tran ,  Ly Th Phan

IPC: A61F2/24

CPC classification number: A61F2/2439 ,  A61F2/2418 ,  A61F2/2436

Abstract: A delivery apparatus for a medical device can include a handle, a shaft, a plurality of sleeves, and a suture. The shaft includes a proximal end portion coupled to the handle and is configured to be disposed outside of a patient's body during an implantation procedure and a distal end portion configured to be disposed inside a patient's body during the implantation procedure. Each of the sleeves includes a connection portion coupled to the distal end portion of the shaft and a receiving portion configured to receive an apex of a stent or a prosthetic heart valve. The suture extends through the shaft and the sleeves and is configured for releasably securing the stent or the prosthetic heart valve to the receiving portions of the sleeves.

公开(公告)号：US20240033080A1

公开(公告)日：2024-02-01

申请号：US18486443

申请日：2023-10-13

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Nicholas Scott Steenwyk ,  Gil Senesh

IPC: A61F2/24 ,  A61B5/00 ,  A61B5/0215

CPC classification number: A61F2/2433 ,  A61B5/6851 ,  A61B5/02158 ,  A61F2250/0098 ,  A61M2025/0002

Abstract: A multiple location pressure sensing device for use with a prosthetic heart valve delivery assembly is disclosed in several examples. As one example, a prosthetic heart valve delivery assembly with a multiple location pressure sensing device can include a delivery apparatus, a guidewire, and a delivery apparatus. The example also includes a first pressure sensor configured to be positioned near an inlet end of a prosthetic heart valve and a second pressure sensor configured to be positioned near an outlet end of the prosthetic heart valve, wherein the first and second sensor are configured to measure a pressure gradient across the prosthetic heart valve.

公开(公告)号：US11806234B2

公开(公告)日：2023-11-07

申请号：US17659169

申请日：2022-04-13

Applicant: Edwards Lifesciences Corporation

Inventor： Nikolai Gurovich ,  Michael Bukin ,  Elena Sherman ,  Tamir S. Levi ,  Ziv Yohanan ,  Gil Senesh ,  Dikla Kersh ,  Alexey Tsypenyuk ,  Waina Michelle Chu ,  Alexander Barash

IPC: A61F2/24 ,  A61F2/90

CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/2433 ,  A61F2/2412 ,  A61F2/90 ,  A61F2220/0075 ,  A61F2230/0023 ,  A61F2230/0052 ,  A61F2250/0003 ,  A61F2250/0039 ,  A61F2250/0069 ,  A61F2310/00017 ,  A61F2310/00029 ,  A61F2310/00059

Abstract: A system can include a delivery catheter comprising a balloon and an implantable prosthetic heart valve. The prosthetic valve can have a plastically expandable and compressible unitary frame comprising a plurality of circumferentially extending rows of angled struts, including first, second, and third rows of angled struts forming rows of diamond-shaped cells, and a valvular structure comprising a plurality of leaflets. A cusp edge portion of each leaflet is connected to the frame by a skirt that is disposed between the frame and the cusp edge portions, the skirt being sutured to selected struts of the frame along diagonal paths extending from an inflow end portion toward an outflow end portion. Each diagonal path along which the skirt is sutured to the frame extends along the first, second, and third rows of angled struts.

公开(公告)号：US11806231B2

公开(公告)日：2023-11-07

申请号：US18114070

申请日：2023-02-24

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Jeanette Jasmine Corona ,  Taylor Michael Winters ,  Ashley Akemi Ishigo ,  Lien Huong Thi Hoang ,  Gil Senesh ,  Vicky Hong Do ,  Quang Ngoc Vu ,  Kim D. Nguyen ,  Brendan Michael Dalbow

IPC: A61F2/24 ,  A61B50/30 ,  A61M25/10 ,  A61F2/95 ,  A61F2/958

CPC classification number: A61F2/24 ,  A61B50/30 ,  A61F2/2418 ,  A61F2/2436 ,  A61M25/10 ,  A61F2/2433 ,  A61F2/9517 ,  A61F2002/9583 ,  A61F2220/0025 ,  A61F2220/0075 ,  A61F2230/0002 ,  A61F2250/0098

Abstract: Methods and systems for attaching a radiopaque marker to a prosthetic heart valve to indicate a location of a commissure of the prosthetic heart valve are disclosed. As one embodiment, a prosthetic heart valve can include a frame including a plurality of struts forming a plurality of cells of the frame arranged between an inflow end and an outflow end of the frame, a plurality of leaflets arranged within the frame, at least one commissure comprising an attachment member arranged across a selected cell of the plurality of cells of the frame and attached to struts of the frame forming the selected cell, and commissure tabs of two adjacent leaflets coupled to the attachment member, and a radiopaque marker arranged on the attachment member of the commissure. The marker is configured to indicate a location of the commissure of the prosthetic heart valve.

公开(公告)号：US11801138B2

公开(公告)日：2023-10-31

申请号：US16808145

申请日：2020-03-03

Applicant: Edwards Lifesciences Corporation

Inventor： Arvin T. Chang ,  Yair A. Neumann ,  Gil Senesh ,  Hernan Altman ,  Scott Louis Pool ,  Hannah Gibson ,  Amanda Kristine Anderson White ,  Peter Phong Tran ,  Ly Th Phan

IPC: A61F2/24

CPC classification number: A61F2/2439 ,  A61F2/2418 ,  A61F2/2436

Abstract: A method for delivering a prosthetic valve to a native annulus of a heart can include inserting a delivery apparatus into a patient's body, advancing the delivery apparatus to an implantation location within the native annulus, retracting a delivery sheath of the delivery apparatus relative to the prosthetic valve to expose the prosthetic valve from a distal end of the delivery sheath, and after the prosthetic valve is exposed from the delivery sheath, expanding the prosthetic valve from a radially compressed state to a radially expanded state by reducing axial tension on a first end and a second end of the prosthetic valve.

公开(公告)号：US20230028375A1

公开(公告)日：2023-01-26

申请号：US17937538

申请日：2022-10-03

Applicant: Edwards Lifesciences Corporation

Inventor： Gil Senesh ,  Jeanette Jasmine Corona ,  Sandip Vasant Pawar

IPC: A61F2/24 ,  A61F2/00

Abstract: A prosthetic heart valve including a frame, leaflet structure, and sealing member disposed around an outer surface of the frame is disclosed. As one example, the sealing member includes an inner layer and a plush outer layer comprising a plush outer surface. The inner layer is arranged against the outer surface of the frame and the outer layer is arranged against and attached to the inner layer. The inner layer is folded over at inflow and outflow ends, in an axial direction relative to a central longitudinal axis of the frame, to overlap respective ends of the outer layer and form tapered folds at opposite ends of the sealing member, each tapered fold including a narrower, first portion where the inner layer folds over and contacts itself and a wider, second portion where the inner layer overlaps an outer surface of an end portion of the outer layer.

公开(公告)号：US20210259832A1

公开(公告)日：2021-08-26

申请号：US17316885

申请日：2021-05-11

Applicant: Edwards Lifesciences Corporation

Inventor： Nikolay Gurovich ,  Michael Bukin ,  Elena Sherman ,  Tamir S. Levi ,  Ziv Yohanan ,  Gil Senesh ,  Dikla Kersh ,  Alexey Tsypenyuk ,  Waina Michelle Chu ,  Alexander Barash

IPC: A61F2/24

Abstract: A prosthetic heart valve can include a radially expandable and compressible frame having an inflow end portion and an outflow end portion, the frame comprising a plurality of struts defining openings between them. The prosthetic valve can further include a valvular structure comprising a plurality of leaflets, each leaflet comprising a main body, opposing tabs on opposite sides of the main body, a coaptation edge portion, and a cusp edge portion. Each tab can be paired with an adjacent tab of an adjacent leaflet to form a plurality of commissures that are fixed relative to the frame, and each leaflet can have opposing edge portions between the opposing tabs and the cusp edge portion that are unattached to the frame, each unattached edge portion defining a gap that extends radially into the main body of the leaflet.

公开(公告)号：US20180326132A1

公开(公告)日：2018-11-15

申请号：US15974911

申请日：2018-05-09

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Gil Senesh

IPC: A61M1/10 ,  A61M1/12

CPC classification number: A61M1/1036 ,  A61M1/106 ,  A61M1/1086 ,  A61M1/122 ,  A61M2205/3334

Abstract: Disclosed herein are systems, devices and methods for heart assist pumps that are implanted using minimally-invasive techniques and that operate by generating a dynamic magnetic field outside of the body to cause a rotor of the heart assist pump to rotate and enhance blood flow through the pump. The disclosed systems, methods, and devices can be utilized in conjunction with a minimally-invasive operation to anchor a micro-pump device at a targeted location within the heart. The pump can be wholly located within the heart without any wires or cannulas penetrating the heart or the body of the patient. Use of this pump as a ventricular assist device can advantageously reduce recovery time, reduce complications, and potentially provide a solution for non-operable patients.

公开(公告)号：US20180028310A1

公开(公告)日：2018-02-01

申请号：US15664430

申请日：2017-07-31

Applicant: Edwards Lifesciences Corporation

Inventor： Nikolay Gurovich ,  Michael Bukin ,  Elena Sherman ,  Tamir S. Levi ,  Ziv Yohanan ,  Gil Senesh ,  Dikla Kersh ,  Alexey M. Tsypenyuk ,  Waina Michelle Chu ,  Alexander Barash

IPC: A61F2/24

Abstract: A prosthetic heart valve can include a radially collapsible and expandable annular frame having a plurality of struts defining openings. The prosthetic heart valve can further include a plurality of leaflets that regulate the flow of blood through the frame. The prosthetic heart valve can also include a sealing member mounted on the frame and having an inner layer and an outer layer. At least the outer layer is mounted on the outside of the frame, and the inner layer covers at least the openings in the frame between adjacent cusp portions of adjacent leaflets and the inner layer does not cover one or more openings in the frame at locations facing the outflow surfaces of the leaflets to permit retrograde blood to flow through the one or more uncovered openings in the frame and into space between the outer layer and the frame.