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公开(公告)号:US12064348B2
公开(公告)日:2024-08-20
申请号:US18311880
申请日:2023-05-03
CPC分类号: A61F2/2418 , A61F2/0077 , A61F2210/0076 , A61F2250/001
摘要: A prosthetic heart valve including a frame, leaflet structure, and sealing member disposed around an outer surface of the frame is disclosed. As one example, the sealing member includes a knitted fabric layer, the knitted fabric layer comprising a base layer forming an inner surface of the knitted fabric layer, where the base layer has a mesh-like structure. The knitted fabric layer further comprises a plush outer surface comprising a plurality of pile yarns knit into loops and that extend outward from the base layer.
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公开(公告)号:US20240216139A1
公开(公告)日:2024-07-04
申请号:US18607271
申请日:2024-03-15
发明人: Nicholas Brandon Aders , Kristen Hicks , Gil Senesh , Michael R. Bialas , Tung T. Le , Sean Chow , Thanh Huy Le
CPC分类号: A61F2/2433 , B23P11/005 , A61F2/9524 , A61F2240/001 , A61F2250/0039
摘要: Devices and methods for crimping a prosthetic heart valve onto a delivery device are described. In some embodiments, valves are crimped over an inflatable balloon and between proximal and distal shoulders mounted on a shaft inside the balloon. Crimping methods can include multiple compression steps with the valve located in different axial positions relative to the crimping jaws at each different step. In some methods, the valve may extend partially outside of the crimping jaws during certain crimping steps, such that the crimping force is only applied to the part of the valve that is inside the jaws. Exemplary crimping devices can include two or more adjacent sets of jaws that close down to different inner diameters, such that different parts of a valve get compressed to different outer diameters at the same time during a single crimping step.
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公开(公告)号:US11872125B2
公开(公告)日:2024-01-16
申请号:US17659577
申请日:2022-04-18
发明人: Nikolai Gurovich , Michael Bukin , Elena Sherman , Tamir S. Levi , Ziv Yohanan , Gil Senesh , Dikla Kersh , Alexey Tsypenyuk , Waina Michelle Chu , Alexander Barash
CPC分类号: A61F2/2418 , A61F2/2409 , A61F2/2433 , A61F2/2412 , A61F2/90 , A61F2220/0075 , A61F2230/0023 , A61F2230/0052 , A61F2250/0003 , A61F2250/0039 , A61F2250/0069 , A61F2310/00017 , A61F2310/00029 , A61F2310/00059
摘要: A system can include a delivery catheter comprising a balloon and an implantable prosthetic heart valve. The prosthetic valve can have a plastically expandable and compressible unitary frame comprising first, second, and third rows of angled struts that define two circumferentially extending rows of diamond-shaped cells that extend continuously around the frame, and a valvular structure comprising a plurality of leaflets. A cusp edge portion of each leaflet is connected to the frame by a skirt that is connected to and disposed between the frame and the cusp edge portions of the leaflets, the skirt being connected to consecutive struts in the first, second, and third rows of struts with sutures. The compressed prosthetic heart valve can be mounted around the balloon and radially expanded to the expanded configuration with the balloon inside a patient's body.
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公开(公告)号:US20230277313A1
公开(公告)日:2023-09-07
申请号:US18316942
申请日:2023-05-12
发明人: Nikolai Gurovich , Michael Bukin , Elena Sherman , Tamir S. Levi , Ziv Yohanan , Gil Senesh , Dikla Kersh , Alexey Tsypenyuk , Waina Michelle Chu , Alexander Barash
IPC分类号: A61F2/24
CPC分类号: A61F2/2418 , A61F2/2433 , A61F2/2409 , A61F2250/0069 , A61F2250/0003 , A61F2230/0052 , A61F2230/0023 , A61F2/2412 , A61F2/90
摘要: A prosthetic heart valve can include a radially expandable and compressible frame having an inflow end, an outflow end, and a plurality of struts. The prosthetic valve can further include a valvular structure comprising a plurality of leaflets, each leaflet comprising a coaptation edge portion and a cusp edge portion. The cusp edge portion of each leaflet can be folded toward the outflow end of the frame along a bending axis and a reinforcing member extends along an outflow surface of the cusp edge portion along the bending axis. The prosthetic heart valve can include a plurality of connecting skirts, each disposed between the cusp edge portion of an adjacent leaflet and the frame. First stitching secures the reinforcing member and the connecting skirts to the cusp edge portions and second stitching secures the connecting skirts to selected struts of the frame.
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公开(公告)号:US11096781B2
公开(公告)日:2021-08-24
申请号:US15664430
申请日:2017-07-31
发明人: Nikolay Gurovich , Michael Bukin , Elena Sherman , Tamir S. Levi , Ziv Yohanan , Gil Senesh , Dikla Kersh , Alexey M. Tsypenyuk , Waina Michelle Chu , Alexander Barash
IPC分类号: A61F2/24
摘要: A prosthetic heart valve can include a radially collapsible and expandable annular frame having a plurality of struts defining openings. The prosthetic heart valve can further include a plurality of leaflets that regulate the flow of blood through the frame. The prosthetic heart valve can also include a sealing member mounted on the frame and having an inner layer and an outer layer. At least the outer layer is mounted on the outside of the frame, and the inner layer covers at least the openings in the frame between adjacent cusp portions of adjacent leaflets and the inner layer does not cover one or more openings in the frame at locations facing the outflow surfaces of the leaflets to permit retrograde blood to flow through the one or more uncovered openings in the frame and into space between the outer layer and the frame.
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6.
公开(公告)号:US20240261089A1
公开(公告)日:2024-08-08
申请号:US18614255
申请日:2024-03-22
发明人: Michael R. Bialas , Kristen Hicks , Michael C. Murad , Gil Senesh , Quang Ngoc Vu , Gonzalo German Angelico , Carla Susana Cerqueira , Victoria Mariko Low , Andrea Fernandez , Karl J. Britzman , Shannon Nicole Ash (formerly Hoye) , Haley Nicole Whitehead
CPC分类号: A61F2/24 , A61B50/30 , A61F2/2418 , A61F2/2436 , A61M25/10 , A61F2/2433 , A61F2/9517 , A61F2002/9583 , A61F2220/0025 , A61F2220/0075 , A61F2230/0002 , A61F2250/0098
摘要: Methods and systems for rotationally aligning a commissure of a prosthetic heart valve with a commissure of a native valve are disclosed. In some examples, a delivery apparatus can include a first shaft configured to rotate around a central longitudinal axis of the delivery apparatus to rotationally align a prosthetic valve mounted on the delivery apparatus with native anatomy, a second shaft extending through the first shaft and having a distal end portion extending distally beyond a distal end portion of the first shaft, an inflatable balloon coupled to the distal end portion of the first shaft, and a distal shoulder mounted on the distal end portion of the second shaft and arranged within a distal end portion of the balloon. The distal shoulder comprises a base portion and a flared portion that extends radially outward from the base portion, and a radiopaque marker is disposed on the flared portion.
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公开(公告)号:US20240024106A1
公开(公告)日:2024-01-25
申请号:US18477329
申请日:2023-09-28
IPC分类号: A61F2/24
CPC分类号: A61F2/243 , A61F2/2412 , A61F2/2445 , A61F2/2472 , A61F2/2409 , A61F2/2439 , A61F2/2466 , A61F2210/0014 , A61F2220/0075 , A61F2230/0069 , A61F2250/0069 , A61B5/1075
摘要: A method of implanting a prosthetic heart valve includes determining from a set of expandable prosthetic heart valves a first prosthetic heart valve. The first prosthetic heart valve has a first nominal diameter less than a native annulus diameter. The method further includes determining a first suggested expanded diameter for the first prosthetic heart valve based on the native annulus diameter, wherein the first suggested expanded diameter is greater than the first nominal diameter, and determining a pressure gradient across the first prosthetic heart valve at the first suggested expanded diameter based at least in part on pressure values from hemodynamic data of the first prosthetic heart valve. The method further includes selecting the prosthetic heart valve from the set of expandable prosthetic heart valves with the suggested expanded diameter resulting in the lowest pressure gradient for implantation from the set of prosthetic heart valves.
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8.
公开(公告)号:US20230190466A1
公开(公告)日:2023-06-22
申请号:US18113552
申请日:2023-02-23
发明人: Michael R. Bialas , Kristen Hicks , Michael C. Murad , Gil Senesh , Quang Ngoc Vu , Gonzalo German Angelico , Carla Susana Cerqueira , Victoria Mariko Low , Andrea Fernandez , Karl J. Britzman , Shannon Nicole Ash (formerly Hoye) , Haley Nicole Whitehead
IPC分类号: A61F2/24
CPC分类号: A61F2/2433 , A61F2/2436 , A61F2/2418 , A61F2250/0098 , A61F2002/9583
摘要: Methods and systems for rotationally aligning a commissure of a prosthetic heart valve with a commissure of a native valve are disclosed. In some examples, a delivery apparatus can include a first shaft configured to rotate around a central longitudinal axis of the delivery apparatus to rotationally align a prosthetic valve mounted on the delivery apparatus with native anatomy, a second shaft extending through the first shaft and having a distal end portion extending distally beyond a distal end portion of the first shaft, an inflatable balloon coupled to the distal end portion of the first shaft, and a distal shoulder mounted on the distal end portion of the second shaft and arranged within a distal end portion of the balloon. The distal shoulder comprises a base portion and a flared portion that extends radially outward from the base portion, and a radiopaque marker is disposed on the flared portion.
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公开(公告)号:US12004947B1
公开(公告)日:2024-06-11
申请号:US18316056
申请日:2023-05-11
IPC分类号: A61F2/24
CPC分类号: A61F2/2415 , A61F2/2412 , A61F2220/0075
摘要: Methods and assemblies for attaching leaflets to a frame of a prosthetic heart valve using a connecting skirt are disclosed. As one example, a prosthetic heart valve can include an annular frame comprising a plurality of struts and a valvular structure mounted within the frame and comprising a plurality of leaflets. A cusp edge portion of each leaflet can be connected to the frame by a connecting skirt, where each connecting skirt comprises a central portion and opposing side base portions on opposite sides of the central portion that are connected to each of and disposed between the frame and the cusp edge portion of the leaflet and each connecting skirt can further comprise side extension portions that extend outward from the cusp edge portion of the leaflet and across struts of the frame that are disposed between cusp edge portions of two adjacent leaflets.
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公开(公告)号:US20240058129A1
公开(公告)日:2024-02-22
申请号:US18112455
申请日:2023-02-21
发明人: Shaun Fetherston , Alexander H. Siemons , Blake W. Axelrod , Gil Senesh , Tomer Saar , Oren Cohen , Elazar Levi Schwarcz , Tamir S. Levi , Michael Bukin , Michael R. Bialas , Timothy A. Geiser , Sudarsan Pranatharthikaran , Carla Susana Cerqueira
CPC分类号: A61F2/2496 , A61B8/445 , A61B8/0883 , A61F2/2433 , A61B2090/064
摘要: A medical balloon sensing assembly constituted of: a handle; a first catheter extending distally from the handle; an inflatable medical balloon, the inflatable medical balloon secured by the first catheter; at least one sensor position member; and at least one sensor secured to the at least one sensor position member, wherein the at least one sensor position member is arranged to contact an outer face of the inflatable medical balloon.
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