公开(公告)号：US20240358511A1

公开(公告)日：2024-10-31

申请号：US18767778

申请日：2024-07-09

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： David Maimon ,  Liron Tayeb ,  Eran Goldberg

IPC: A61F2/24 ,  A61F2/95 ,  A61M25/00

CPC classification number: A61F2/2439 ,  A61F2/2427 ,  A61F2/2433 ,  A61M25/0023 ,  A61F2/9517 ,  A61M2025/0024

Abstract: The active introducer sheath systems disclosed herein are expanded by activating a translation mechanism at the handle. The sheath has an inner cylindrical structure of comingled fixed and mobile elongate rods bound together by an attachment line. Activating the translation mechanism causes the mobile rods to move axially with respect to the fixed rods, changing the internal tension in the attachment line. Increased tension draws the fixed and mobile rods closer together, decreasing the diameter of the cylindrical structure. Decreased tension in the attachment line enables the fixed and mobile rods to move apart, increasing the diameter of the cylindrical structure. A prosthetic device, such as a prosthetic heart valve, can be routed through the expanded sheath and to the implantation site. During implantation, the sheath can be contracted back to its original outer diameter, and expanded again for retrieval of the delivery apparatus.

公开(公告)号：US12083012B2

公开(公告)日：2024-09-10

申请号：US17824411

申请日：2022-05-25

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Boaz Manash ,  Eyal Leiba ,  Ziv Yohanan ,  Yair A. Neumann ,  Anatoly Dvorsky ,  Jonathan Bar-Or ,  Oren Cohen ,  Ofir Witzman ,  Liron Tayeb ,  Elazar Levi Schwarcz ,  Noam Miller ,  Tomer Saar

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/243 ,  A61F2220/0041 ,  A61F2250/001 ,  A61F2250/0069

Abstract: An assembly can comprise a prosthetic valve comprising a radially expandable and compressible frame and a rotatable screw connected to the frame, where the screw comprises a screw head having an annular bore with internal threads, and where the screw is rotatable to radially expand the frame. The assembly further comprises a delivery apparatus releasably coupled to the screw, the delivery apparatus comprising a first shaft and a first head disposed at an end of the first shaft, the first head comprising external threads configured to engage with the internal threads of the screw head, and a second shaft that is coaxial with and surrounds the first shaft, the second shaft comprising a second head disposed at an end of the second shaft. The second head is configured to releasably engage with an exterior surface of the screw head and rotate the screw.

公开(公告)号：US12070388B2

公开(公告)日：2024-08-27

申请号：US18138651

申请日：2023-04-24

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： David Maimon ,  Liron Tayeb ,  Eran Goldberg

IPC: A61F2/24 ,  A61M25/00 ,  A61F2/95

CPC classification number: A61F2/2439 ,  A61F2/2427 ,  A61F2/2433 ,  A61M25/0023 ,  A61F2/9517 ,  A61M2025/0024

Abstract: The active introducer sheath systems disclosed herein are expanded by activating a translation mechanism at the handle. The sheath has an inner cylindrical structure of comingled fixed and mobile elongate rods bound together by an attachment line. Activating the translation mechanism causes the mobile rods to move axially with respect to the fixed rods, changing the internal tension in the attachment line. Increased tension draws the fixed and mobile rods closer together, decreasing the diameter of the cylindrical structure. Decreased tension in the attachment line enables the fixed and mobile rods to move apart, increasing the diameter of the cylindrical structure. A prosthetic device, such as a prosthetic heart valve, can be routed through the expanded sheath and to the implantation site. During implantation, the sheath can be contracted back to its original outer diameter, and expanded again for retrieval of the delivery apparatus.

公开(公告)号：US20240189100A1

公开(公告)日：2024-06-13

申请号：US18582897

申请日：2024-02-21

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： David Maimon ,  Boaz Manash ,  Eyal Leiba ,  Ziv Yohanan ,  Yair A. Neumann ,  Anatoly Dvorsky ,  Jonathan Bar-Or ,  Oren Cohen ,  Ofir Witzman ,  Liron Tayeb ,  Elazar Levi Schwarcz ,  Noam Miller ,  Tomer Saar

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/243 ,  A61F2220/0041 ,  A61F2250/001 ,  A61F2250/0069

Abstract: A method can comprise deploying a prosthetic valve with a delivery apparatus, where the prosthetic valve comprises a frame and a rotatable screw connected to the frame, and where the screw comprises a screw head having an annular bore with internal threads. The delivery apparatus is releasably coupled to the screw and can comprise a first shaft and a first head disposed at an end of the first shaft, the first head comprising external threads releasably engaged with the internal threads of the screw head, and a second shaft that is coaxial with and surrounds the first shaft, the second shaft comprising a second head disposed at an end of the second shaft, the second head releasably engaged with an exterior surface of the screw head. Deploying the valve includes radially expanding the prosthetic valve by rotating the screw with the delivery apparatus.

公开(公告)号：US20230277306A1

公开(公告)日：2023-09-07

申请号：US18195808

申请日：2023-05-10

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Tamir S. Levi ,  Giolnara Pinhas ,  Liraz Marom ,  Elena Sherman ,  Noam Mizrahi ,  Delfin Rafael Ruiz ,  Sandip Vasant Pawar ,  Liron Tayeb

IPC: A61F2/24 ,  A61F2/00

CPC classification number: A61F2/2415 ,  A61F2/0077 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2210/0076 ,  A61F2230/0069 ,  A61F2250/0069

Abstract: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration includes an annular frame having an inflow end, an outflow end, and a longitudinal axis. A leaflet structure is positioned within the frame and secured thereto, and a sealing element is secured to the frame. The sealing element includes a first woven portion extending circumferentially around the frame. The first woven portion includes a plurality of interwoven filaments. The sealing element further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. At least a portion of the filaments comprise a hydrophilic surface treatment.

公开(公告)号：US11717397B2

公开(公告)日：2023-08-08

申请号：US16860742

申请日：2020-04-28

Applicant: Edwards Lifesciences Corporation

Inventor： Liron Tayeb ,  Ilan Tamir

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61F2/2415 ,  A61F2/2418 ,  A61F2/24 ,  A61F2/2412 ,  A61F2220/0075 ,  A61F2230/0091 ,  A61F2250/006 ,  A61F2250/0069

Abstract: A covering layer for a transcatheter heart valve is in various embodiments configured to prevent or reduce damage to the native valve tissue around the site where the prosthetic valve is implanted. In some cases, prosthetic valves are manufactured with the covering layer attached. Other covering layers are stand-alone accessories that can be mounted onto pre-existing prosthetic valves by an end user. Covering layers that can be mounted by an end user are provided with various features that can facilitate easier attachment of the covering layer to the prosthetic valve, which further reduces the possibility of damage to the covering layer or to the valve. Another covering is provided with two layers in order to insulate and protect the native tissue surrounding the implant from damage due to friction or abrasion, and/or other movement driven wear.

公开(公告)号：US11291540B2

公开(公告)日：2022-04-05

申请号：US16034794

申请日：2018-07-13

Applicant: Edwards Lifesciences Corporation

Inventor： Liron Tayeb ,  Eran Goldberg ,  David Maimon ,  Adi Carmi ,  Arie Tylis ,  Ofir Witzman ,  Ralph Schneider ,  Mohammad Jafari ,  Hengchu Cao ,  Eason Michael Abbott ,  Dustin P. Armer ,  Michael D. Franklin ,  Tomer Saar ,  Anatoly Dvorsky ,  John J. Desrosiers ,  Daniel James Murray ,  Michael G. Valdez ,  Assaf Bash ,  Amir Blumenfeld ,  Noa Axelrod ,  Eitan Atias

IPC: A61F2/24 ,  A61F2/90 ,  A61F2/88

Abstract: Docking stations for transcatheter valves are described. The docking stations can include an expandable frame, at least one sealing portion, and a valve seat. The expandable frame can be configured to conform to an interior shape of a portion of the circulatory system when expanded inside the circulatory system. The sealing portion can be configured to contact an interior surface of the circulatory system to create a seal. The valve seat can be connected to the expandable frame and can be configured to support an expandable transcatheter valve. The docking stations are adaptable to different anatomies/locations to allow implantation of a transcatheter valve in a variety of anatomies/locations.

公开(公告)号：US20210315697A1

公开(公告)日：2021-10-14

申请号：US17359332

申请日：2021-06-25

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Liron Tayeb ,  Eran Goldberg

IPC: A61F2/24 ,  A61M25/00

Abstract: The active introducer sheath systems disclosed herein are expanded by activating a translation mechanism at the handle. The sheath has an inner cylindrical structure of comingled fixed and mobile elongate rods bound together by an attachment line. Activating the translation mechanism causes the mobile rods to move axially with respect to the fixed rods, changing the internal tension in the attachment line. Increased tension draws the fixed and mobile rods closer together, decreasing the diameter of the cylindrical structure. Decreased tension in the attachment line enables the fixed and mobile rods to move apart, increasing the diameter of the cylindrical structure. A prosthetic device, such as a prosthetic heart valve, can be routed through the expanded sheath and to the implantation site. During implantation, the sheath can be contracted back to its original outer diameter, and expanded again for retrieval of the delivery apparatus.

公开(公告)号：US20210085459A1

公开(公告)日：2021-03-25

申请号：US17113268

申请日：2020-12-07

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Eran Goldberg ,  Liron Tayeb

IPC: A61F2/24 ,  A61M25/00 ,  A61M25/06

Abstract: The expandable sheath and methods of use disclosed herein are used to deliver a prosthetic device through a patient's vasculature. The sheath is constructed to be expandable in the circumferential direction, while maintaining sufficient stiffness in the longitudinal direction to withstand pushing and resist kinking. The sheath includes a plurality of curved arms extending outwardly from a longitudinally extending spine. The curved arms move away from the longitudinal axis of the sheath when pushed radially outwardly by a passing prosthetic device, and move back toward the longitudinal axis once the prosthetic device has passed.

公开(公告)号：US10603165B2

公开(公告)日：2020-03-31

申请号：US15831197

申请日：2017-12-04

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Boaz Manash ,  Eyal Leiba ,  Ziv Yohanan ,  Yair A. Neumann ,  Anatoly Dvorsky ,  Jonathan Bar-Or ,  Oren Cohen ,  Ofir Witzman ,  Liron Tayeb ,  Elazar Levi Schwarcz ,  Noam Miller ,  Tomer Saar

IPC: A61F2/24

Abstract: An assembly can comprise a radially expandable and compressible annular frame, at least one linear actuator assembly coupled to the frame and at least one locking mechanism coupled to the frame. The linear actuator can be configured to apply a distally directed force and/or a proximally directed force to the frame to radially expand or compress the frame. The locking mechanism can comprise a first sleeve member connected to the frame at a first location, a second sleeve member having internal threads and being connected to the frame at a second location, and a first screw configured to engage the internal threads of the second sleeve member to retain the frame in a radially expanded state.