公开(公告)号：US20210068957A1

公开(公告)日：2021-03-11

申请号：US17100381

申请日：2020-11-20

Applicant: Edwards Lifesciences Corporation

Inventor： Yaron Keidar ,  Wesley V. Adzich ,  Dan Rottenberg ,  Boaz Manash ,  Alon Nahshon

IPC: A61F2/24

Abstract: An active annuloplasty ring holder having a template that can be folded or pivoted to the side allowing the template to align longitudinally with the handle and enter the patient's chest through a small incision. The holder may include a mechanism to remotely detach sutures fastening the ring to the holder, thereby detaching the ring while avoiding the risk associated with introducing a scalpel into the operating field. A detachment mechanism may include a movable pin actuated by a pull wire that releases a plurality of holding sutures, or a hot wire, knives, or pull wire that severs the sutures. The holder may have a built-in light source for better visualization of the ring inside the heart. The holder may also have an optical means of visualizing the inside of the heart from the proximal end of the handle.

公开(公告)号：US20200237513A1

公开(公告)日：2020-07-30

申请号：US16852341

申请日：2020-04-17

Applicant: Edwards Lifesciences Corporation

Inventor： Yaron Keidar ,  Adam J. Yestrepsky

IPC: A61F2/24 ,  A61B17/04 ,  A61B17/30

Abstract: Methods and devices for the treatment of cardiac valve dysfunction through the placement of lines and anchors. The lines and anchors can form artificial chordae between valve leaflets and the ventricular wall or papillary muscles or connect the two valve leaflets together. The methods and devices offer a mechanism for performing this technique with the heart still beating, and allows for the placement of multiple lines with a single device.

公开(公告)号：US10350062B2

公开(公告)日：2019-07-16

申请号：US15653390

申请日：2017-07-18

Applicant: Edwards Lifesciences Corporation

Inventor： Matthew A. Peterson ,  Seung-Beom Yi ,  Siddharth Vad ,  Travis Zenyo Oba ,  Lauren R. Freschauf ,  Amanda French ,  Yaron Keidar ,  Yuanlong Du ,  Gregory Bak-Boychuk ,  Kevin M. Golemo ,  Alexander H. Cooper

IPC: A61F2/24

Abstract: A prosthesis can be configured to grasp intralumenal tissue when deployed within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the body cavity and a valve body. The expandable frame can include a frame body and a supplemental frame. The valve body can include a plurality of leaflets and one or more intermediate components. The one or more intermediate components can couple at least a portion of the leaflets to the expandable frame. The prosthesis can include an annular flap positioned around an exterior of the expandable frame.

公开(公告)号：US20190201195A1

公开(公告)日：2019-07-04

申请号：US16298616

申请日：2019-03-11

Applicant: Edwards Lifesciences Corporation

Inventor： Stanton J. Rowe ,  Larry L. Wood ,  Henry Bourang ,  George Bakis ,  Benjamin Spenser ,  Netanel Benichou ,  Assaf Bash ,  Yaron Keidar

IPC: A61F2/24 ,  A61L27/36 ,  A61F2/90

Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment.

公开(公告)号：US20190091017A1

公开(公告)日：2019-03-28

申请号：US16197280

申请日：2018-11-20

Applicant: Edwards Lifesciences Corporation

Inventor： Stanton J. Rowe ,  Larry L. Wood ,  Henry Bourang ,  George Bakis ,  Benjamin Spenser ,  Netanel Benichou ,  Assaf Bash ,  Yaron Keidar

IPC: A61F2/24 ,  A61F2/90 ,  A61L27/36

Abstract: A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment.

公开(公告)号：US20170304050A1

公开(公告)日：2017-10-26

申请号：US15491809

申请日：2017-04-19

Applicant: Edwards Lifesciences Corporation

Inventor： Yaron Keidar ,  Adam J. Yestrepsky

IPC: A61F2/24 ,  A61B17/30 ,  A61B17/04

CPC classification number: A61F2/2457 ,  A61B17/0401 ,  A61B17/30 ,  A61B2017/00243 ,  A61B2017/0406 ,  A61B2017/0409 ,  A61B2017/0464 ,  A61B2017/308 ,  A61F2/2466

Abstract: Methods and devices for the treatment of cardiac valve dysfunction through the placement of lines and anchors. The lines and anchors can form artificial chordae between valve leaflets and the ventricular wall or papillary muscles or connect the two valve leaflets together. The methods and devices offer a mechanism for performing this technique with the heart still beating, and allows for the placement of multiple lines with a single device.

公开(公告)号：US20170224487A1

公开(公告)日：2017-08-10

申请号：US15498213

申请日：2017-04-26

Applicant: Edwards Lifesciences Corporation

Inventor： Mark A. Konno ,  Yaron Keidar

IPC: A61F2/24

CPC classification number: A61F2/2442 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/2433 ,  A61F2/2445 ,  A61F2/958 ,  A61F2220/0075 ,  A61F2230/0034 ,  A61F2250/001 ,  A61F2250/0071

Abstract: The invention is a cardiac implant, and associated methods therefore, configured to repair and/or replace a native heart valve, and having a support frame configured to be reshaped into an expanded/changed form in order to receive and/or support an expandable prosthetic heart valve therein. The implant may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace/repair a native valve (or other prosthetic heart valve), but to assume a generally non-rigid and/or expanded/expandable form when subjected to an outward force such as that provided by a dilation balloon. The implant may be configured to have a generally D-shaped configuration when initially implanted, but to assume a generally circular form when subjected to an outward force such as that provided by a dilation balloon.

公开(公告)号：US20230248249A1

公开(公告)日：2023-08-10

申请号：US18174155

申请日：2023-02-24

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Yaron Keidar ,  Mark Simon Vreeke ,  Ming H. Wu ,  Alexander H. Siemons

IPC: A61B5/0215 ,  A61B5/00

CPC classification number: A61B5/0215 ,  A61B5/6869 ,  A61B5/6885

Abstract: An implantable sensor device includes a sensor-support substrate, a microelectromechanical systems (MEMS) pressure sensor device mounted to the sensor-support substrate, a transduction medium applied over the pressure sensor device, and a biocompatibility layer applied over the transduction medium

公开(公告)号：US11529233B2

公开(公告)日：2022-12-20

申请号：US16852341

申请日：2020-04-17

Applicant: Edwards Lifesciences Corporation

Inventor： Yaron Keidar ,  Adam J. Yestrepsky

IPC: A61F2/24 ,  A61B17/04 ,  A61B17/30 ,  A61B17/00

Abstract: Methods and devices for the treatment of cardiac valve dysfunction through the placement of lines and anchors. The lines and anchors can form artificial chordae between valve leaflets and the ventricular wall or papillary muscles or connect the two valve leaflets together. The methods and devices offer a mechanism for performing this technique with the heart still beating, and allows for the placement of multiple lines with a single device.

公开(公告)号：US11471275B2

公开(公告)日：2022-10-18

申请号：US16888649

申请日：2020-05-29

Applicant: Edwards Lifesciences Corporation

Inventor： Salvador Marquez ,  Da-Yu Chang ,  Cindy Woo ,  Hao-Chung Yang ,  Lynn T. Dang ,  Javier A. Sanguinetti ,  Alexander H. Siemons ,  Yaron Keidar ,  Virginia Qi Lin ,  Brian S. Conklin ,  Donald E. Bobo, Jr.

IPC: A61F2/24 ,  A61B5/026 ,  A61B5/00

Abstract: Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.