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46 条记录 (耗时 0.035 秒)

    Shutter device and camera equipped with the same
    31.
    发明授权
    Shutter device and camera equipped with the same 失效
    快门装置和相机配备相同

    公开(公告)号：US5940640A

    公开(公告)日：1999-08-17

    申请号：US36460

    申请日：1998-03-06

    申请人： Akira Karasawa

    发明人： Akira Karasawa

    IPC分类号： G03B9/08 ,  G03B7/10 ,  G03B7/26 ,  G03B9/36 ,  G03B9/62

    CPC分类号： G03B9/62 ,  G03B7/10 ,  G03B7/26

    摘要： A shutter device having a first light blocking structure arranged to initiate an exposure and a second light blocking structure arranged to terminate the exposure, includes a first energy storage element arranged to store electric energy for causing the first light blocking structure to start operating, a second energy storage element arranged to store electric energy for causing the second light blocking structure to start operating, and a charging control circuit arranged to effect control of charging of the first energy storage element and the second energy storage element, wherein the charging control circuit varies the control of charging in accordance with a set exposure time.

    摘要翻译： 具有布置成开始曝光的第一遮光结构和布置成终止曝光的第二遮光结构的快门装置包括布置成存储电能以使第一遮光结构开始运作的第一能量存储元件，第二 储能元件，被配置为存储用于使第二遮光结构开始运转的电能;以及充电控制电路，被配置为实现第一能量存储元件和第二能量存储元件的充电控制，其中充电控制电路改变 根据设定的曝光时间控制充电。

    Xanthine derivatives
    33.
    发明授权
    Xanthine derivatives 失效
    黄嘌呤衍生物

    公开(公告)号：US5342841A

    公开(公告)日：1994-08-30

    申请号：US29069

    申请日：1993-03-10

    申请人： Fumio Suzuki ,  Junichi Shimada ,  Akira Karasawa ,  Hideaki Mizumoto ,  Hiroshi Kase ,  Hiromi Nonaka

    发明人： Fumio Suzuki ,  Junichi Shimada ,  Akira Karasawa ,  Hideaki Mizumoto ,  Hiroshi Kase ,  Hiromi Nonaka

    IPC分类号： C07D473/06 ,  A61K31/52 ,  C07D473/02

    CPC分类号： C07D473/06

    摘要： A xanthine derivative of the formula (I): ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and are substituted or unsubstituted alicyclic alkyl; m1 and m2 are the same or different and represent an integer of 0 to 2; and Q represents ##STR2## (in which R.sup.3 and R.sup.4 are the same or different and are substituted or unsubstituted alicyclic alkyl) or ##STR3## (in which n is 0 or 1, and Y is a single bond or alkylene); or a pharmaceutically acceptable salt thereof is disclosed.This derivative has diuretic activity and renal protecting activity.

    摘要翻译： 式（I）的黄嘌呤衍生物：其中R1和R2相同或不同，为取代或未取代的脂环族烷基; m1和m2相同或不同，表示0〜2的整数。 和Q表示（其中R 3和R 4相同或不同，是取代或未取代的脂环族烷基）或（其中n为0或1，Y为单键或亚烷基）。 或其药学上可接受的盐。 该衍生物具有利尿活性和肾脏保护活性。

    Therapeutic agent for bladder irritative symptoms associated with benign prostatic hyperplasia
    35.
    发明授权
    Therapeutic agent for bladder irritative symptoms associated with benign prostatic hyperplasia 失效

    公开(公告)号：US07354949B2

    公开(公告)日：2008-04-08

    申请号：US10472148

    申请日：2002-03-29

    申请人： Tsuyoshi Yamagata ,  Kaoru Atsuki ,  Tetsuji Ohno ,  Shiro Shirakura ,  Akira Karasawa

    发明人： Tsuyoshi Yamagata ,  Kaoru Atsuki ,  Tetsuji Ohno ,  Shiro Shirakura ,  Akira Karasawa

    IPC分类号： A61K31/38 ,  A61K31/44 ,  A61K31/42

    CPC分类号： C07D495/04 ,  A61K31/55

    摘要： The present invention provides a therapeutic agent for bladder irritative symptoms associated with benign prostatic hyperplasia comprising, as an active ingredient, a tricyclic compound represented by formula (I): [wherein R1 represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkoxy or halogen; X1-X2-X3 represents CR5═CR6—CR7═CR8, N(O)m═CR6—CR7═CR8, CR5═CR6—N(O)m═CR8, CR5═CR6—CR7═N(O)m, CR5═CR6—O, CR5═CR6—S, O—CR7═CR8, S—CR7═CR8 or O—CR7═N; Y represents 13 CH2S—, —CH2SO—, —CH2SO2—, —CH2O—, —CH═CH—, —(CH2)p—, —SCH2—, —SOCH2—, —SO2CH2— or —OCH2—; and R2 represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkenyl, substituted or unsubstituted lower alkoxy, amino, mono(substituted or unsubstituted lower alkyl)-substituted amino, di(substituted or unsubstituted lower alkyl)-substituted amino, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted aralkylamino, substituted or unsubstituted arylamino or a substituted or unsubstituted heteroalicyclic group] or a pharmaceutically acceptable salt thereof.

    Tricyclic compounds
    36.
    发明授权
    Tricyclic compounds 失效
    三环化合物

    公开(公告)号：US06211227B1

    公开(公告)日：2001-04-03

    申请号：US09417626

    申请日：1999-10-14

    申请人： Makoto Yoshida ,  Takashi Seishi ,  Shigeru Aono ,  Tsuyoshi Yamagata ,  Kaoru Atsuki ,  Toshiaki Kumazawa ,  Haruki Takai ,  Koji Suzuki ,  Akira Karasawa

    发明人： Makoto Yoshida ,  Takashi Seishi ,  Shigeru Aono ,  Tsuyoshi Yamagata ,  Kaoru Atsuki ,  Toshiaki Kumazawa ,  Haruki Takai ,  Koji Suzuki ,  Akira Karasawa

    IPC分类号： A61K3138

    CPC分类号： C07D495/04 ,  C07D313/12 ,  C07D337/12

    摘要： The present invention provides tricyclic compounds which are useful for the treatment of pollakiuria and urinary incontinence and which are represented by general formula (I): (wherein R1 represents hydrogen, substituted or unsubstituted lower alkyl, etc.; X1—X2—X3 represents CR5═CR6—CR7═CR8 (wherein R5, R6, R7 and R8, which may be the same or different, each represents hydrogen, substituted or unsubstituted lower alkyl, hydroxy, substituted or unsubstituted lower alkoxy, etc.), N(O)m═CR5—CR6═CR7 (wherein R5, R6 and R7 have the same significances as defined above, and m represents 0 or 1), S—CR7═CR8 (wherein R7 and R8 have the same significances as defined above), etc.; and when R2 represents hydrogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkoxy, a substituted or unsubstituted N-substituted heterocyclic group, (wherein n is 0 or 1; R3 and R4, which may be the same or different, each represents hydrogen, substituted or unsubstituted lower alkyl, trifluoromethyl, etc., or R3 and R4 may be combined together to form cyclic alkyl; and Q represents hydroxy, halogen, etc.), etc., Y represents —CH2SO2—, —SCH2—, —SOCH2—, —SO2CH2—, etc.) and pharmaceutically acceptable salts thereof.

    摘要翻译： 本发明提供可用于治疗尿频和尿失禁的三环化合物，其由通式（I）表示：其中R 1表示氢，取代或未取代的低级烷基等; X 1 -X 2 -X 3表示CR 5 = CR6-CR7 = CR8（其中R5，R6，R7和R8可以相同或不同，各自表示氢，取代或未取代的低级烷基，羟基，取代或未取代的低级烷氧基等），N（O）m = CR5-CR6 = CR7（其中R5，R6和R7具有与上述相同的含义，m表示0或1），S-CR 7 = CR 8（其中R 7和R 8具有与上述相同的含义）等 ;当R 2表示氢时，取代或未取代的低级烷基，取代或未取代的低级烷氧基，取代或未取代的N-取代的杂环基，（其中n为0或1; R 3和R 4各自可相同或不同） 代表氢，取代或未取代的低级烷基，三氟甲基 脲基甲基等，或者R 3和R 4可以组合在一起形成环烷基; 和Q表示羟基，卤素等）等，Y表示-CH 2 SO 2 - ， - CH 2 - ， - SOCH 2 - ， - SO 2 CH 2 - 等）及其药学上可接受的盐。

    Quinazolines and phthalazines having adenosine uptake inhibitor activity
    37.
    发明授权
    Quinazolines and phthalazines having adenosine uptake inhibitor activity 失效
    喹唑啉和具有腺苷摄取抑制剂活性的酞嗪酮

    公开(公告)号：US5648353A

    公开(公告)日：1997-07-15

    申请号：US446235

    申请日：1995-05-22

    申请人： Shigeki Fujiwara ,  Daisuke Machii ,  Haruki Takai ,  Hiromi Nonaka ,  Hiroshi Kase ,  Kozo Yao ,  Michiyo Kawakage ,  Hideaki Kusaka ,  Akira Karasawa

    发明人： Shigeki Fujiwara ,  Daisuke Machii ,  Haruki Takai ,  Hiromi Nonaka ,  Hiroshi Kase ,  Kozo Yao ,  Michiyo Kawakage ,  Hideaki Kusaka ,  Akira Karasawa

    IPC分类号： C07D401/14 ,  C07D491/04 ,  C07D401/04 ,  A61K31/445 ,  A61K31/50 ,  A61K31/505

    CPC分类号： C07D401/14 ,  C07D491/04

    摘要： The present invention relates to an adenosine uptake inhibitor and an agent for the myocardium protection or the prevention or treatment of inflammatory edema, comprising a 1,2,3,4-tetrahydro-2,4-dioxoquinazoline derivative represented by formula (I): ##STR1## wherein R.sup.1 represents hydrogen, substituted or unsubstituted lower alkyl, alkenyl, or substituted or unsubstituted aralkyl; R.sup.2, R.sup.3, R.sup.4, and R.sup.5 independently represent hydrogen, halogen, amino, mono- or di(lower alkyl)amino, lower alkanoylamino, nitro, cyano, substituted or unsubstituted lower alkyl, hydroxy, lower alkoxy, lower alkylthio, carboxy, lower alkoxycarbonyl, lower alkanoyl, aralkyloxy, or lower alkanoyloxy; R.sup.6, R.sup.7, R.sup.8, and R.sup.9 independently represent hydrogen, hydroxy, substituted or unsubstituted lower alkoxy, or aralkyloxy, or any adjoining two of them are combined to form methylenedioxy; R.sup.10 represents hydrogen or lower alkyl; and Y and Z independently represent N or C--R.sup.11 (wherein R.sup.11 represents hydrogen, substituted or unsubstituted lower alkyl, or halogen),or a pharmaceutically acceptable salt thereof as an active ingredient.

    摘要翻译： 本发明涉及腺苷摄取抑制剂和用于心肌保护或预防或治疗炎性水肿的药剂，其包含由式（I）表示的1,2,3,4-四氢-2,4-二氧代喹唑啉衍生物： （I）其中R 1表示氢，取代或未取代的低级烷基，烯基或取代或未取代的芳烷基; R2，R3，R4和R5独立地表示氢，卤素，氨基，一或二（低级烷基）氨基，低级烷酰基氨基，硝基，氰基，取代或未取代的低级烷基，羟基，低级烷氧基，低级烷硫基，羧基，低级 烷氧基羰基，低级烷酰基，芳烷氧基或低级烷酰氧基; R 6，R 7，R 8和R 9独立地表示氢，羟基，取代或未取代的低级烷氧基或芳烷氧基，或者它们中的任何相邻的两个被结合形成亚甲二氧基; R 10表示氢或低级烷基; 并且Y和Z独立地表示作为活性成分的N或C-R11（其中R11表示氢，取代或未取代的低级烷基或卤素）或其药学上可接受的盐。

    IMAGE PICKUP APPARATUS WITH BUILT-IN FLASH
    39.
    发明申请
    IMAGE PICKUP APPARATUS WITH BUILT-IN FLASH 有权
    具有内置闪存的图像拾取装置

    公开(公告)号：US20110052172A1

    公开(公告)日：2011-03-03

    申请号：US12854556

    申请日：2010-08-11

    申请人： Akira Karasawa

    发明人： Akira Karasawa

    IPC分类号： G03B15/03

    CPC分类号： G03B15/03

    摘要： An image pickup apparatus includes a motor, a shutter charge mechanism which rotates the motor in a first direction to perform a charge operation of a shutter, a flash pop-up mechanism which rotates the motor in a second direction to move a flash to an up state, a state detector which detects the up state of the flash, a clutch mechanism which cuts off a transmission between the motor and the flash pop-up mechanism when the motor rotates in the first direction, and cuts off a transmission between the motor and the shutter charge mechanism when the motor rotates in the second direction, and a controller which controls the motor to rotate in the first direction to drive the shutter charge mechanism when the state detector detects the up state of the flash after the motor rotates in the second direction to drive the flash pop-up mechanism.

    摘要翻译： 图像拾取装置包括电动机，使电动机沿第一方向旋转以执行快门的充电操作的快门充电机构，使电动机沿第二方向旋转以使闪光灯向上移动的闪光弹出机构 状态，检测闪光灯的上升状态的状态检测器，当电动机沿第一方向旋转时切断电动机与闪光灯弹出机构之间的传输的离合器机构，并且切断电动机和 当电动机沿第二方向旋转时的快门充电机构，以及当电动机在第二方向旋转时状态检测器检测到闪光灯的向上状态时控制电动机沿第一方向旋转以驱动快门充电机构的控制器 方向来驱动flash弹出机制。

    Remedies for vesical hyperactivity
    40.
    发明授权
    Remedies for vesical hyperactivity 失效
    用于膀胱活动过度的补救措施

    公开(公告)号：US07276532B2

    公开(公告)日：2007-10-02

    申请号：US10472143

    申请日：2002-03-29

    申请人： Tsuyoshi Yamagata ,  Kaoru Atsuki ,  Tetsuji Ohno ,  Shiro Shirakura ,  Akira Karasawa

    发明人： Tsuyoshi Yamagata ,  Kaoru Atsuki ,  Tetsuji Ohno ,  Shiro Shirakura ,  Akira Karasawa

    IPC分类号： A61K31/38

    CPC分类号： C07D495/04 ,  A61K31/55 ,  C07D337/12

    摘要： The present invention provides a therapeutic agent for overactive bladder comprising, as an active ingredient, a tricyclic compound represented by formula (I): [wherein R1 represents a hydrogen atom, substituted or unsubstituted lower alkyl, and the like; X1—X2—X3 represents CR5═CR6—CR7═CR8, CR5═CR6—S, and the like; Y represents —CH2S—, —SOCH2—, and the like; and R2 represents a hydrogen atom, and the like] or a pharmaceutically acceptable salt thereof.

    摘要翻译： 本发明提供一种活性过氧化物的治疗剂，其包含作为活性成分的由式（I）表示的三环化合物：其中R 1表示氢原子，取代或未取代的低级烷基，和 类似; X 1 - 2 - - - - - - - - - - - - - - - - - - （3） CR 7 -CR 8，CR 5 -CR 6 -S等; Y表示-CH 2 -S-，-SOCH 2 - 等; 和R 2表示氢原子等]或其药学上可接受的盐。