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公开(公告)号:US20180259433A1
公开(公告)日:2018-09-13
申请号:US15756965
申请日:2015-10-23
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Viktor Shkolnikov , Anita Rogacs
CPC classification number: G01N1/4005 , B01D61/38 , B01D2313/345 , G01N21/658 , G01N2001/4011 , G01N2001/4038
Abstract: A target analyte is extracted out of a sample fluid in a sample fluid passage by diffusing the target analyte through a supported liquid membrane to a product fluid passage. Extraction of the target analyte is accelerated by applying an electric field across and perpendicular to the supported liquid membrane with electrodes. Passage of selected ions across an exchange membrane extending between one of the electrodes and the supported liquid membrane is inhibited.
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公开(公告)号:US20220088595A1
公开(公告)日:2022-03-24
申请号:US17415066
申请日:2019-06-04
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Fausto D'Apuzzo , Steven Barcelo , Anita Rogacs
Abstract: Integrated microfluidic ejector chips and methods of use are provided. An example of an integrated microfluidic ejector chip includes a first set of microfluidic ejectors fed with a reference solution, and a second set of microfluidic ejectors fed with a sample solution. The first set of microfluidic ejectors and the second set of microfluidic ejectors are disposed on the integrated microfluidic ejector chip to print a pattern of proximately located spots on a sensor.
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公开(公告)号:US20220080372A1
公开(公告)日:2022-03-17
申请号:US17415217
申请日:2019-06-04
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Steven Barcelo , Fausto D'Apuzzo , Anita Rogacs
IPC: B01F33/301 , G01N21/25 , G05D11/13 , B01F35/83 , B01F31/85
Abstract: A system and a method for on-chip dilution of a calibration solution are provided. An exemplary system includes a microfluidic ejector chip. The microfluidic ejector chip includes a calibration reservoir to contain a calibration standard and a dilution reservoir to contain a dilution solvent. A first fluid control device couples the calibration reservoir to a mixing chamber, and a second fluid control device couples a dilution reservoir to the mixing chamber. The mixing chamber is fluidically coupled to a microfluidic ejector.
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公开(公告)号:US11255792B2
公开(公告)日:2022-02-22
申请号:US16098058
申请日:2016-07-21
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Ning Ge , Anita Rogacs , Steven J. Simske , Milo Overbay , Viktor Shkolnikov
Abstract: A surface enhanced Raman spectroscopy (SERS) sensor may include a nano structured surface and a nonstoichiometric oxide layer. The nano structured surfers may include a first peak, a second peak and a valley between the first peak and the second peak. The non-stoichiometric oxide layer may include a first portion on the first peak and a second portion on the second peak.
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公开(公告)号:US11144576B2
公开(公告)日:2021-10-12
申请号:US16074704
申请日:2016-10-28
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Lei Liu , Anita Rogacs
Abstract: A method may include sensing first data samples from a first set of different subjects having a membership in a target class and sensing second data samples from a second set of different subjects not having a membership in the target class, wherein each of the first data samples and the second data samples includes a composite of individual data features. The individual data features from each composite of the first data samples and the second data samples are extracted and quantified. Sets of features and associated weightings of a target class model are identified based upon quantified values of the individual features from each composite of the first samples and the second samples to create a model representing a fingerprint of the target class to determine membership status of a sample having an unknown membership status with respect to the target class.
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公开(公告)号:US11125693B2
公开(公告)日:2021-09-21
申请号:US16076077
申请日:2017-01-31
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Fausto D'Apuzzo , Aleksandr Polyakov , Anita Rogacs
IPC: G01N21/65 , G01N21/552
Abstract: A surface enhanced infrared absorption stage may include a substrate, a static island extending from the substrate and a movable nano finger extending from the substrate. The static island may have a plasmonically active island cap and a dimension parallel to the substrate of at least one micrometer. The movable nano finger may be aligned with the dimension. The movable nano finger may have a plasmonically active finger cap closable to less than or equal to 5 nm of the island cap.
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公开(公告)号:US11060958B2
公开(公告)日:2021-07-13
申请号:US15770453
申请日:2016-02-27
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Viktor Shkolnikov , Anita Rogacs
Abstract: A sample preparation system includes a sample input, a first chamber fluidly coupled to the sample input and containing a sample preparation reagent, a second chamber containing a surface enhanced Raman spectroscopy (SERS) sensor structure and a third chamber containing a sensor preparation solution. The sample input, the first chamber and the second chamber are fluidly coupled to one another in a series and the third chamber is fluidly coupled to the third chamber outside of the series so as to sequentially direct a sample received by the sample input through the first chamber to the second chamber and out of the second chamber and so as to direct the sensor preparation solution into the second chamber following discharge of the sample out of the second chamber.
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公开(公告)号:US20210102160A1
公开(公告)日:2021-04-08
申请号:US17125914
申请日:2020-12-17
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Viktor Shkolnikov , Anita Rogacs
Abstract: An apparatus may include a lower chamber to contain a culture that emits volatile organic compounds, an upper chamber, a first sensor within the upper chamber, a second sensor within the upper chamber in a transport selector. The second sensor may be different than the first sensor so as to sense volatile organic compounds differently than the first sensor. The transport selector is to transport a selected portion of the volatile organic compounds emitted from the lower chamber to the first sensor and a second portion of the volatile organic compounds emitted from the lower chamber to the second sensor.
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公开(公告)号:US20210080323A1
公开(公告)日:2021-03-18
申请号:US16611968
申请日:2017-07-19
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Steven Barcelo , Anita Rogacs
Abstract: A spectroscopic device is provided. The spectroscopic device includes a plurality of design groups on a substrate. Each design group includes a plurality of collapsed groups separated by bare regions of substrate, wherein the edges of each design group is configured to enhance the pinning of a solvent drying line at the edge of the design group. Each collapsed group comprises at least 2 flexible columnar structures, and each flexible columnar structure comprises a metal cap.
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公开(公告)号:US10828639B2
公开(公告)日:2020-11-10
申请号:US15546882
申请日:2015-04-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Anita Rogacs , Alexander Govyadinov
Abstract: A fluid exit passage is at a location along a microfluidic channel. A fluid displacement device is proximate the location along the microfluidic channel. A constituent locator distinguishes a target constituent in a fluid within the microfluidic channel from remaining non-target constituents and locate the target constituent proximate the fluid exit passage. A controller selectively actuates the fluid displacement device when the target constituent is proximate the fluid exit passage to discharge the target constituent from the microfluidic channel through the fluid exit passage.
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