公开(公告)号：US10363372B2

公开(公告)日：2019-07-30

申请号：US15674974

申请日：2017-08-11

Applicant: Insulet Corporation

Inventor： David Nazzaro

IPC: A61M5/315 ,  A61M5/24 ,  A61M5/28 ,  A61M5/145 ,  A61M5/31

Abstract: Plunger systems for expelling a liquid drug from a drug container within a wearable drug delivery device are provided. A rotation system coupled to a plunger rotates the plunger about a central axis of the plunger to overcome a static friction between the plunger and the drug container. After rotating the plunger, a drive system moves the plunger forward into the drug container to expel the liquid drug for delivery to the patient. A collapsible plunger includes a cavity. A radial torsion spring positioned in the cavity can provide an outward radial force on the collapsible plunger. The cavity enables the collapsible plunger to compress radially when entering and passing through a region of a drug container having a relatively narrower width. The radial torsion spring can radially expand the collapsible plunger when entering and passing through a region of the drug container having a relatively wider width.

公开(公告)号：US20170219555A1

公开(公告)日：2017-08-03

申请号：US15009979

申请日：2016-01-29

Applicant: Insulet Corporation

Inventor： David Nazzaro ,  John Bussiere ,  Jason B. O'Connor ,  John D. D'Arco

IPC: G01N33/487 ,  G01N33/49

Abstract: A medical device to test bodily fluid, the device comprising a light emitting source, the light emitting source arranged to emit light inside the medical device; a test strip port, the test strip port comprising a test strip port receptacle to receive a test strip; and the light emitting source and the test strip port arranged such that, when the light emitting source emits light, at least a portion of the light emitted from the light emitting source is redirected inside the medical device to provide redirected light inside the medical device, and at least a portion of the redirected light lights the test strip port from inside the medical device in a manner than the redirected light is visible outside the test strip port.

公开(公告)号：US11992653B2

公开(公告)日：2024-05-28

申请号：US16515749

申请日：2019-07-18

Applicant: Insulet Corporation

Inventor： Jason O'Connor ,  Ian McLaughlin ,  Daniel Allis ,  David Nazzaro

IPC: A61M5/145 ,  A61M5/142 ,  A61M5/158 ,  A61M5/162 ,  A61M5/168

CPC classification number: A61M5/14566 ,  A61M5/14248 ,  A61M5/1582 ,  A61M5/162 ,  A61M5/16881 ,  A61M2005/14252 ,  A61M2205/3379 ,  A61M2205/583

Abstract: Disclosed are examples for a system for drug delivery and components thereof. The system may include an on-body pump device and a secondary unit. The on-body pump device may include a reservoir and a fluid pathway. The reservoir may be configured to hold a liquid drug. The secondary unit may be removably coupled to the on-body pump device. The secondary unit may be configured to receive a prefilled cartridge containing a liquid drug, expel the liquid drug from the prefilled cartridge, and deliver the liquid drug to the reservoir of the on-body pump device via the fluid pathway. Examples of variations to the secondary unit are also disclosed.

公开(公告)号：US11957875B2

公开(公告)日：2024-04-16

申请号：US17112314

申请日：2020-12-04

Applicant: INSULET CORPORATION

Inventor： Yibin Zheng ,  Joon Bok Lee ,  Steven Cardinali ,  Jason O'Connor ,  Eric Benjamin ,  Ian McLaughlin ,  David Nazzaro ,  Ashutosh Zade

IPC: A61M5/172 ,  A61M5/142 ,  G01N33/49 ,  G16H10/60 ,  G16H20/17 ,  G16H20/60 ,  G16H40/40 ,  G16H40/67 ,  G16H50/30 ,  G16H50/70

CPC classification number: A61M5/1723 ,  A61M5/14248 ,  G01N33/49 ,  G16H10/60 ,  G16H20/17 ,  G16H20/60 ,  G16H40/40 ,  G16H40/67 ,  G16H50/30 ,  G16H50/70 ,  A61M2005/1726 ,  A61M2205/505 ,  A61M2205/52 ,  A61M2230/201

Abstract: Disclosed are a device, system, methods and computer-readable medium products that provide an updated insulin-to-carbohydrate ratio and an updated total daily insulin. The described processes may be used for periodic updating of the insulin-to-carbohydrate ratio and the total daily insulin. The insulin-to-carbohydrate ratio and/or the total may be used in the calculation of new doses of insulin that a drug delivery device may be commanded to deliver to a user.

公开(公告)号：US11744944B2

公开(公告)日：2023-09-05

申请号：US16898529

申请日：2020-06-11

Applicant: Insulet Corporation

Inventor： Jason O'Connor ,  Daniel Allis ,  David Nazzaro ,  John R. Bussiere ,  John D'Arco

IPC: A61M5/172 ,  G16H40/63 ,  G16H20/17 ,  A61M5/142

CPC classification number: A61M5/1723 ,  A61M5/14248 ,  G16H20/17 ,  G16H40/63 ,  A61M2205/27 ,  A61M2205/3569 ,  A61M2205/3584 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583 ,  A61M2205/8206 ,  A61M2230/201

Abstract: Systems and methods for automatically delivering medication to a user. A sensor coupled to a user can collect information regarding the user. A controller can use the collected information to determine an amount of medication to provide the user. The controller can instruct a drug delivery device to dispense the medication to the user. The drug delivery device can be a wearable insulin pump that is directly coupled to the user. The controller can be part of or implemented in a cellphone. A user can be required to provide a confirmation input to allow a determined amount of insulin to be provided to the user based on detected glucose levels of the user. The sensor, controller, and drug delivery device can communicate wirelessly.

公开(公告)号：US11497856B2

公开(公告)日：2022-11-15

申请号：US16534376

申请日：2019-08-07

Applicant: Insulet Corporation

Inventor： David Nazzaro ,  Ian McLaughlin ,  Daniel Allis ,  Simon Kozin ,  Maureen McCaffrey

IPC: A61M5/315 ,  A61M5/142 ,  A61M5/145 ,  A61M5/20

Abstract: Systems and methods for monitoring an operational state and/or a fill status of a drug container of a drug delivery device are provided. The drug container can hold a liquid drug. A plunger can be positioned within the drug container. A drive system can advance the plunger to expel the liquid drug from the container. A monitoring system can detect a movement and/or a position of the plunger and/or any component coupled to the plunger. The detection can enable determination of an amount of liquid drug that has been expelled and/or an amount of liquid drug remaining in the drug container. Dosing rates, flow rates, and dosage completion can also be determined.

公开(公告)号：US11458250B2

公开(公告)日：2022-10-04

申请号：US16428294

申请日：2019-05-31

Applicant: Insulet Corporation

Inventor： Kenneth Phillips ,  Steven Cardinali ,  David Nazzaro

IPC: A61M5/168 ,  A61M5/145 ,  G01F23/263 ,  G01F17/00 ,  A61M5/142

Abstract: Reservoir systems with improved wake up and fill volume detection techniques are provided. An example reservoir system may include a flexible reservoir and electrical components for detecting fill volume of the flexible reservoir without adversely affecting performance of the flexible reservoir when receiving or dispensing a liquid drug.

公开(公告)号：US11439765B2

公开(公告)日：2022-09-13

申请号：US16524647

申请日：2019-07-29

Applicant: Insulet Corporation

Inventor： David Nazzaro

IPC: A61M5/315 ,  A61M5/142 ,  A61M5/145 ,  A61M5/20

Abstract: Variable fill drug delivery devices for delivering a therapeutic agent to a patient are provided. A variable fill drug delivery device includes a drug container to store a variable amount (or user-selectable amount) of a therapeutic agent. A plunger of the variable fill drug delivery device is positioned in the drug container. An infusion engine of the variable fill device is coupled to the plunger. The infusion engine retains the plunger prior to activation of the variable fill drug delivery device and releases the plunger after activation of the variable fill drug delivery device. After activation, the infusion engine drives the plunger from a first position within the drug container to a second position within the drug container to expel the variable amount of the therapeutic agent from the drug container for delivery to a patient.

公开(公告)号：US11364341B2

公开(公告)日：2022-06-21

申请号：US16519349

申请日：2019-07-23

Applicant: Insulet Corporation

Inventor： Robert Rioux ,  David Nazzaro

IPC: A61M5/172 ,  A61M5/142 ,  A61M5/145 ,  A61M5/158

Abstract: Systems and methods for delivering a medication to a person experiencing an emergency medical event without requiring intervention or action on the part of the person. A device encases a reservoir of medication and a delivery mechanism. Sensors in the housing sense a physical attribute of the person and circuitry monitors information collected by the sensors to determine if the person is experiencing a severe medical condition or event based on the information. An input device on or in the housing, such as a button, may be used or activated by the person if the detected condition or event is a false positive to cancel further action. If the system does not include the button or if the user does not press it in time, the system activates the delivery device and injects the medication into the person.

公开(公告)号：US10973978B2

公开(公告)日：2021-04-13

申请号：US16049388

申请日：2018-07-30

Applicant: Insulet Corporation

Inventor： David Nazzaro ,  Ian McLaughlin ,  Daniel Allis ,  Jason O'Connor

IPC: A61M5/168 ,  A61M5/28 ,  A61M5/32 ,  A61M5/315

Abstract: A fluid flow regulator of a fluid delivery system that can adjust a flow rate of a liquid drug dispensed from a liquid drug container to a user is provided. The fluid flow regulator can be coupled to an end of the liquid drug container. The fluid flow regulator can include a compliance plate and a flow channel selector plate having a fluid flow channel. The flow channel selector plate can be rotated relative to the compliance plate and the liquid drug container to expose a selected portion of the fluid flow channel to openings in the compliance plate that are in fluid communication with the liquid drug stored in the liquid drug container. The selected portion of the fluid flow channel can correspond to a corresponding flow resistance of the liquid drug through the fluid flow channel, thereby regulating the flow of the liquid drug to the user.