公开(公告)号：US20090029855A1

公开(公告)日：2009-01-29

申请号：US12282608

申请日：2007-03-12

申请人： Michael Puhl ,  Wassilios Grammenos ,  Joachim Rheinheimer ,  Jan Klaas Lohmann ,  Michael Rack ,  Liliana Parra Rapado ,  Christopher Koradin ,  Jurgen Langewald ,  Deborah L. Culbertson ,  Douglas D. Anspaugh ,  Hassan Oloumi-Sadeghi ,  Henry Van Tuyl Cotter ,  David G. Kuhn

发明人： Michael Puhl ,  Wassilios Grammenos ,  Joachim Rheinheimer ,  Jan Klaas Lohmann ,  Michael Rack ,  Liliana Parra Rapado ,  Christopher Koradin ,  Jurgen Langewald ,  Deborah L. Culbertson ,  Douglas D. Anspaugh ,  Hassan Oloumi-Sadeghi ,  Henry Van Tuyl Cotter ,  David G. Kuhn

IPC分类号： A01N25/26 ,  C07D215/14 ,  A01N43/42 ,  A01N59/26 ,  A01P5/00 ,  A01P7/04

CPC分类号： C07D215/12 ,  C07D215/60

摘要： This invention relates to quinoline derivatives of formula I wherein R1, R2, R3 are each independently halogen, hydroxy, cyano, amino, nitro, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C7-cycloalkyl, C3-C7-cycloalkyl-C1-C4-alkyl, C1-C6-alkoxy, C2-C6-alkenyloxy, C2-C6-alkynyloxy, C1-C4-alkoxy-C1-C4-alkoxy, C3-C7-cycloalkyl-C1-C4-alkoxy, C(OH)(CF3)2, C1-C6-haloalkyl, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-haloalkylthio, C1-C6-alkylsulfinyl, C1-C6-haloalkylsulfinyl, C1-C6-alkylsulfonyl, C1-C6-haloalkylsulfonyl, C(Ra)═O, C(Ra)═NORb, C(═O)ORx, or C(═O)NRxRy; Ra is hydrogen or C1-C4-alkyl; Rb is hydrogen, C1-C4-alkyl, C2-C4-alkenyl, C2-C4-alkynyl, C1-C4-haloalkyl, or C2-C4-haloalkenyl; Rx, Ry are each independently hydrogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy-C1-C4-alkyl, C1-C4-thioalkyl-C1-C4-alkyl, C1-C4-alkyl-S(═O)C1-C4-alkyl, C1-C4-alkyl-S(═O)2C1-C4-alkyl, C3-C6-cyloalkyl, C1-C4-alkyl-C3-C6-cycloalkyl, C3-C6-alkenyl, C3-C6-alkinyl; R4, R5, R6, R7 are each independently hydrogen, halogen, cyano, amino, nitro, hydroxy, C1-C6-alkyl, C1-C6-alkoxy, C1-C6-haloalkyl, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-haloalkylthio, C1-C6-alkylsulfinyl, C1-C6-haloalkylsulfinyl, C1-C6-alkylsulfonyl, C1-C6-haloalkylsulfonyl, or C(═O)ORc; Rc is hydrogen, C1-C6-alkyl, C2-C6-alkenyl, or C2-C6-alkinyl; m and n are each independently 1, 2, 3, 4, or 5; p is 0, 1, 2, 3, 4, or 5; and the N-oxides, enantiomers, diastereomers and salts thereof, processes and intermediates for the preparation of compounds I, use of compounds I for combating insects, acarids, or nematodes and a method for treating, controlling, preventing or protecting animals against infestation or infection by parasites using compounds I.

摘要翻译： 本发明涉及式I的喹啉衍生物，其中R 1，R 2，R 3各自独立地为卤素，羟基，氰基，氨基，硝基，C 1 -C 6烷基，C 2 -C 6 - 烯基，C 2 -C 6炔基，C 3 -C 7 - 环烷基，C 3 -C 7 - 环烷基-C 1 -C 4 - 烷基，C 1 -C 6 - 烷氧基，C 2 -C 6 - 烯氧基，C 2 -C 6 - 炔氧基，C 1 -C 4烷氧基-C 1 -C 4烷氧基，C 3 -C 7 - 环烷基 - C 1 -C 6烷氧基，C（OH）（CF 3）2，C 1 -C 6卤代烷基，C 1 -C 6卤代烷氧基，C 1 -C 6烷硫基，C 1 -C 6卤代烷硫基，C 1 -C 6烷基亚磺酰基， C 1 -C 6烷基磺酰基，C 1 -C 6卤代烷基磺酰基，C（R a）-O，C（R a）-NOR b，C（-O）OR x或C（-O）NR x R y; R a是氢或C 1 -C 4 - 烷基; R b是氢，C 1 -C 4 - 烷基，C 2 -C 4 - 烯基，C 2 -C 4 - 炔基，C 1 -C 4卤代烷基或C 2 -C 4 - 卤代烯基; R x，R y各自独立地为氢，C 1 -C 4 - 烷基，C 1 -C 4 - 卤代烷基，C 1 -C 4 - 烷氧基-C 1 -C 4烷基，C 1 -C 4 - 硫代烷基-C 1 -C 4烷基，C 1 -C 4烷基 - S（-O）C 1 -C 4 - 烷基，C 1 -C 4烷基-S（-O）2 C 1 -C 4烷基，C 3 -C 6 - 环烷基，C 1 -C 4烷基-C 3 -C 6环烷基，C 3 -C 6 - 烯基，C 3 -C 6 - 炔基; R4，R5，R6，R7各自独立地为氢，卤素，氰基，氨基，硝基，羟基，C1-C6-烷基，C1-C6-烷氧基，C1-C6-卤代烷基，C1-C6-卤代烷氧基，C1-C6- C 1 -C 6烷基亚磺酰基，C 1 -C 6烷基磺酰基，C 1 -C 6卤代烷基磺酰基或C（-O）OR c; R c是氢，C 1 -C 6 - 烷基，C 2 -C 6 - 烯基或C 2 -C 6 - 炔基; m和n各自独立地为1,2,3,4或5; p是0，1，2，3，4或5; 及其N-氧化物，对映异构体，非对映异构体及其盐，制备化合物I的方法和中间体，化合物I用于防治昆虫，螨虫或线虫的用途，以及用于治疗，控制，预防或保护动物免受感染或 使用化合物I的寄生虫感染

公开(公告)号：US20080214394A1

公开(公告)日：2008-09-04

申请号：US11908744

申请日：2006-03-15

申请人： Michael Puhl ,  Christopher Koradin ,  Joachim Rheinheimer ,  Wassilios Grammenos ,  Jan Klaas Lohmann ,  Ernst Baumann ,  Wolfgang von Deyn ,  Jurgen Langewald ,  Norbert Gotz ,  Douglas D. Anspaugh ,  Deborah L. Culbertson ,  Henry Van Tuyl Cotter ,  Hassan Olumi-Sadeghi

发明人： Michael Puhl ,  Christopher Koradin ,  Joachim Rheinheimer ,  Wassilios Grammenos ,  Jan Klaas Lohmann ,  Ernst Baumann ,  Wolfgang von Deyn ,  Jurgen Langewald ,  Norbert Gotz ,  Douglas D. Anspaugh ,  Deborah L. Culbertson ,  Henry Van Tuyl Cotter ,  Hassan Olumi-Sadeghi

IPC分类号： A01N43/40 ,  C07D215/36 ,  C07D401/12 ,  A61K31/44

CPC分类号： C07D213/42 ,  A01N43/40 ,  A01N43/42 ,  C07D215/12 ,  C07D409/12

摘要： N-(4-Pyridyl)methylsulfonamides for combating arthropodal pests The present invention relates to the use of N-(4-pyridyl)methylsulfonamides of the formula for combating arthropodal pests (harmful arthropodes) and for protecting materials against infestation and/or destruction by said pests: (I) where the substituents are as follows: R1 is hydrogen, C1-C4-alkyl, C1-C4-alkoxy, C2-C4-alkenyl, C2-C4-alkynyl or benzyl; R2, R3, R4, R5 independently of one another are hydrogen, halogen, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-haloalkoxy or C1-C4-haloalkyl; R2 and R3 or R4 and R5 together with the carbon atoms to which they are attached may also form a condensed 5- or 6-membered hydro-carbon ring, it being possible for the hydrocarbon ring to carry one or two groups R2′, R3′, R2′, R3′ independently of one another are halogen, C1-C4-alkyl, C1-C4-alkoxy, halomethoxy or halomethyl; X is a cyclic radical selected from phenyl, naphthyl and five- or six-membered saturated, partially unsaturated or aromatic heterocycles, the heterocycle being attached to the sulfur atom via a carbon atom and containing 1, 2 or 4 heteroatoms selected from the group consisting of O, N and S, where the cyclic radical X may carry 1, 2, 3 or 4 substituents Ra.

公开(公告)号：US20080139581A1

公开(公告)日：2008-06-12

申请号：US11885536

申请日：2006-03-02

申请人： Wassilios Grammenos ,  Thomas Grote ,  Udo Hunger ,  Jan Klaas Lohmann ,  Bern Muller ,  Joachim Rheinheimer ,  Peter Schafer ,  Anja Schwogler ,  Michael Rack

发明人： Wassilios Grammenos ,  Thomas Grote ,  Udo Hunger ,  Jan Klaas Lohmann ,  Bern Muller ,  Joachim Rheinheimer ,  Peter Schafer ,  Anja Schwogler ,  Michael Rack

IPC分类号： A01N43/90 ,  A01P3/00 ,  C07D487/04

CPC分类号： C07D487/04

摘要： 2-Substituted 7-aminoazolopyrimidines of the formula I in which the substituents are as defined below: R1 is hydrogen, halogen, cyano, alkyl, haloalkyl, alkenyl, alkynyl, cycloalkyl, alkoxy, alkoxyalkyl, benzyloxyalkyl, alkoxyalkenyl or alkoxyalkynyl; R2 is hydrogen, halogen, cyano, alkyl, haloalkyl, alkenyl, alkynyl, cycloalkyl, alkoxy, alkoxyalkyl and alkylthioalkyl, where the carbon chains in R1 and/or R2 may be substituted according to the description; R3 is halogen, cyano, NRARB, hydroxyl, mercapto, alkyl, haloalkyl, cycloalkyl, alkoxy, alkylthio, cycloalkoxy, cycloalkylthio, carboxyl, formyl, alkylcarbonyl, alkoxycarbonyl, alkenyloxycarbonyl, alkynyloxycarbonyl, phenyl, phenoxy, phenylthio, benzyloxy, benzylthio, alkyl-S(O)m—; A is N and CRx; Rx is hydrogen or one of the groups mentioned under R3; processes and intermediates for preparing these compounds, compositions comprising them and their use for controlling phytopathogenic harmful fungi.

摘要翻译： 2-取代的式I的7-氨基偶氮嘧啶，其中取代基如下：R 1是氢，卤素，氰基，烷基，卤代烷基，烯基，炔基，环烷基，烷氧基，烷氧基烷基，苄氧基烷基 ，烷氧基烯基或烷氧基炔基; R 2是氢，卤素，氰基，烷基，卤代烷基，烯基，炔基，环烷基，烷氧基，烷氧基烷基和烷硫基烷基，其中R 1和/或R ^{2可以根据描述代替; R 3是卤素，氰基，NR B，B，羟基，巯基，烷基，卤代烷基，环烷基，烷氧基，烷硫基，环烷氧基，环烷硫基 ，羧基，甲酰基，烷基羰基，烷氧基羰基，烯氧基羰基，炔氧基羰基，苯基，苯氧基，苯硫基，苄氧基，苄硫基，烷基-S（O） A是N和CR R x是氢或R 3中提到的基团之一; 制备这些化合物的方法和中间体，包含它们的组合物及其用于控制​​植物病原性有害真菌的用途。}

公开(公告)号：US08115012B2

公开(公告)日：2012-02-14

申请号：US12513003

申请日：2007-11-02

申请人： Martin Sukopp ,  Michael Rack ,  Sebastian Peer Smidt ,  Sandra Löhr ,  Michael Keil ,  Jochen Dietz ,  Joachim Rheinheimer ,  Thomas Grote ,  Thomas Zierke ,  Jan Klaas Lohmann

发明人： Martin Sukopp ,  Michael Rack ,  Sebastian Peer Smidt ,  Sandra Löhr ,  Michael Keil ,  Jochen Dietz ,  Joachim Rheinheimer ,  Thomas Grote ,  Thomas Zierke ,  Jan Klaas Lohmann

IPC分类号： C07D231/10 ,  C07F7/08

CPC分类号： C07D231/14

摘要： The present invention relates to a process for preparing difluoromethyl-substituted pyrazol-4-ylcarboxylates of the formula I in which R1 is C1-C8-alkyl, C3-C8-cycloalkyl, C1-C4-alkoxy-C1-C4-alkyl, etc.; and R2 is hydrogen, C1-C4-alkyl, benzyl or phenyl, wherein a) a compound of the general formula II in which X is fluorine, chlorine or bromine, R1 has one of the meanings given above and R4 is C1-C8-alkyl, C3-C8-cycloalkyl, C2-C8-alkenyl, benzyl or phenyl, is reacted with a silane compound of the general formula R3nSiCl(4-n) in which n is 1, 2 or 3 and the substituents R3 are independently of one another selected from the group consisting of C1-C8-alkyl and phenyl and with a metal selected from the metals of groups 1, 2, 3, 4 and 12 of the Periodic Table of the Elements having a redox potential of less than −0.7 V, based on a normal hydrogen electrode (at 25° C. and 101.325 kPa); and b) the reaction mixture from step a) is reacted with a compound of the general formula III R2HN—NH2  (III) in which R2 has one of the meanings given above.

摘要翻译： 本发明涉及制备式Ⅰ的二氟甲基取代的吡唑-4-基羧酸酯的方法，其中R 1是C 1 -C 8烷基，C 3 -C 8环烷基，C 1 -C 4烷氧基-C 1 -C 4烷基等 。 R 2是氢，C 1 -C 4 - 烷基，苄基或苯基，其中a）通式II的化合物，其中X是氟，氯或溴，R 1具有上面给出的含义之一，R 4是C 1 -C 8 - 烷基，C 3 -C 8 - 环烷基，C 2 -C 8 - 烯基，苄基或苯基与通式R 3 n SiCl（4-n）的硅烷化合物反应，其中n为1,2或3，取代基R 3独立地为 选自由C 1 -C 8 - 烷基和苯基组成的组中的一种，以及选自元素周期表第1,2,3,4和12族金属的金属，其氧化还原电位小于-0.7 V，基于正常的氢电极（在25℃和101.325kPa）; 和b）将来自步骤a）的反应混合物与通式III的化合物R2HN-NH2（III）反应，其中R2具有上述含义之一。

公开(公告)号：US20100069646A1

公开(公告)日：2010-03-18

申请号：US12513003

申请日：2007-11-02

申请人： Martin Sukopp ,  Michael Rack ,  Sebastian Peer Smidt ,  Sandra Löhr ,  Michael Keil ,  Jochen Dietz ,  Joachim Rheinheimer ,  Thomas Grote ,  Thomas Zierke ,  Jan Klaas Lohmann

发明人： Martin Sukopp ,  Michael Rack ,  Sebastian Peer Smidt ,  Sandra Löhr ,  Michael Keil ,  Jochen Dietz ,  Joachim Rheinheimer ,  Thomas Grote ,  Thomas Zierke ,  Jan Klaas Lohmann

IPC分类号： C07D231/10 ,  C07F7/08

CPC分类号： C07D231/14

摘要： The present invention relates to a process for preparing difluoromethyl-substituted pyrazol-4-ylcarboxylates of the formula I in which R1 is C1-C8-alkyl, C3-C8-cycloalkyl, C1-C4-alkoxy-C1-C4-alkyl, etc.; and R2 is hydrogen, C1-C4-alkyl, benzyl or phenyl, wherein a) a compound of the general formula II in which X is fluorine, chlorine or bromine, R1 has one of the meanings given above and R4 is C1-C8-alkyl, C3-C8-cycloalkyl, C2-C8-alkenyl, benzyl or phenyl, is reacted with a silane compound of the general formula R3nSiCl(4-n) in which n is 1, 2 or 3 and the substituents R3 are independently of one another selected from the group consisting of C1-C8-alkyl and phenyl and with a metal selected from the metals of groups 1, 2, 3, 4 and 12 of the Periodic Table of the Elements having a redox potential of less than −0.7 V, based on a normal hydrogen electrode (at 25° C. and 101.325 kPa); and b) the reaction mixture from step a) is reacted with a compound of the general formula III R2HN—NH2   (III) in which R2 has one of the meanings given above.

摘要翻译： 本发明涉及制备式Ⅰ的二氟甲基取代的吡唑-4-基羧酸酯的方法，其中R 1是C 1 -C 8烷基，C 3 -C 8环烷基，C 1 -C 4烷氧基-C 1 -C 4烷基等 。 并且R 2是氢，C 1 -C 4 - 烷基，苄基或苯基，其中a）通式II的化合物，其中X是氟，氯或溴，R 1具有上面给出的含义之一，R 4是C 1 -C 8 - 烷基，C 3 -C 8 - 环烷基，C 2 -C 8 - 烯基，苄基或苯基与通式R 3 n SiCl（4-n）的硅烷化合物反应，其中n为1,2或3，取代基R 3独立地为 选自由C 1 -C 8 - 烷基和苯基组成的组中的一种，以及选自元素周期表第1,2,3,4和12族金属的金属，其氧化还原电位小于-0.7 V，基于正常的氢电极（在25℃和101.325kPa）; 和b）将来自步骤a）的反应混合物与通式III的化合物R2HN-NH2（III）反应，其中R2具有上述含义之一。

公开(公告)号：US20070270311A1

公开(公告)日：2007-11-22

申请号：US11661566

申请日：2005-09-02

申请人： Carsten Blettner ,  Jordi Blasco ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Udo Hunger ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Jochen Dietz ,  John-Bryan Speakman ,  Thorsten Jabs ,  Siegfried Strathmann ,  Ulrich Schofl ,  Maria Scherer ,  Reinhard Stierl

发明人： Carsten Blettner ,  Jordi Blasco ,  Bernd Muller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Udo Hunger ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Jochen Dietz ,  John-Bryan Speakman ,  Thorsten Jabs ,  Siegfried Strathmann ,  Ulrich Schofl ,  Maria Scherer ,  Reinhard Stierl

IPC分类号： A01N43/90 ,  A01P3/00 ,  C07D487/02

CPC分类号： A01N43/90 ,  A01N47/06 ,  A01N47/12 ,  A01N47/16 ,  C07D487/04

摘要： 6-Phenyl-7-aminotriazolopyrimidines of the formula I in which the substituents are as defined below: R1 is hydrogen, alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, haloalkenyl, cycloalkenyl, halocycloalkenyl, alkynyl, haloalkynyl or phenyl, naphthyl, or a five- or six-membered saturated, partially unsaturated or aromatic heterocycle, which comprises one to four heteroatoms from the group consisting of O, N and S, R2 is alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, haloalkenyl, cycloalkenyl, halocycloalkenyl, alkynyl, haloalkynyl or phenyl, naphthyl, or a five- or six-membered saturated, partially unsaturated or aromatic heterocycle which comprises one to four heteroatoms from the group consisting of O, N and S, R3,R4,R5,R6,R7 are hydrogen or one of the groups mentioned under R2, R4, together with R3 or R6, may also form a five- or six-membered saturated or unsaturated ring which, in addition to carbon atoms, may comprise one to three further heteroatoms from the group consisting of O, N and S as ring members; R2 with R3, R4 with R5, R6 with R7 may in each case together, with formation of spiro groups, also form a C2-C5-alkylene, or alkenylene or alkynylene chain which may be interrupted by one to three heteroatoms from the group consisting of O, N and S; p is zero or 1; L is halogen, alkyl, haloalkyl, alkoxy, cyano, nitro, amino, alkylamino, dialkylamino, alkylcarbonylamino, C(O)—R, S(O)n—R; where n is zero, 1 or 2; R is hydrogen, alkyl, haloalkyl, alkoxy, alkenyloxy, alkynyloxy, amino, alkylamino, dialkylamino; m is 1, 2, 3, 4 or 5; X is halogen, cyano, alkyl, alkoxy, alkenyloxy, alkynyloxy or haloalkoxy; Y is oxygen or sulfur; Z is hydrogen, alkyl, haloalkyl, cycloalkyl, alkylcarbonyl, cycloalkylcarbonyl, alkenyl, haloalkenyl, cycloalkenyl, alkynyl, haloalkynyl, phenyl, naphthyl, a five- to ten-membered saturated, partially unsaturated or aromatic heterocycle which comprises one to four heteroatoms from the group consisting of O, N and S; or Z together with R4 or R6 may also form a five- or six-membered saturated or unsaturated ring which, in addition to carbon atoms and Y, may comprise one or two further heteroatoms from the group consisting of O, N and S as ring members the groups R1 to R7, Z and R may be substituted according to the description; processes for preparing these compounds, compositions comprising them and their use for controlling phytopathogenic harmful fungi.

公开(公告)号：US20080132522A1

公开(公告)日：2008-06-05

申请号：US11631006

申请日：2005-07-12

申请人： Joachim Rheinheimer ,  Frank Schieweck ,  Thomas Grote ,  Carsten Blettner ,  Anja Schwogler ,  Markus Gewehr ,  Wassilios Grammenos ,  Udo Hunger ,  Bernd Muller ,  Peter Schafer ,  Jochen Dietz ,  John-Bryan Speakman ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

发明人： Joachim Rheinheimer ,  Frank Schieweck ,  Thomas Grote ,  Carsten Blettner ,  Anja Schwogler ,  Markus Gewehr ,  Wassilios Grammenos ,  Udo Hunger ,  Bernd Muller ,  Peter Schafer ,  Jochen Dietz ,  John-Bryan Speakman ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

IPC分类号： A01N43/54 ,  C07D401/04 ,  A01P3/00 ,  A01P13/00 ,  A01P15/00

CPC分类号： C07D239/34 ,  C07D401/04 ,  C07D403/12

摘要： The invention relates to 2-substituted pyrimidines of the formula I in which the index n and the substituents R1 to R4, B and L are as defined in the description and Y is a group —O— or —S—, and to processes for their preparation, pesticidal compositions and methods for controlling harmful fungi and animal pests using the compounds according to the invention.

摘要翻译： 本发明涉及式I的2-取代嘧啶，其中指数n和取代基R 1至R 4，B和L如说明书中所定义，以及 Y是基团-O-或-S-，并且使用本发明的化合物进行制备，杀虫组合物和控制有害真菌和动物害虫的方法。

公开(公告)号：US20080249113A1

公开(公告)日：2008-10-09

申请号：US11659192

申请日：2005-07-28

申请人： Carsten Blettner ,  Jochen Dietz ,  Wassilios Grammenos ,  Thomas Grote ,  Udo Hunger ,  Bernd Muller ,  Matthias Niedenbruck ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Barbara Nave ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

发明人： Carsten Blettner ,  Jochen Dietz ,  Wassilios Grammenos ,  Thomas Grote ,  Udo Hunger ,  Bernd Muller ,  Matthias Niedenbruck ,  Joachim Rheinheimer ,  Peter Schafer ,  Frank Schieweck ,  Anja Schwogler ,  Barbara Nave ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schofl ,  Reinhard Stierl

IPC分类号： A01N43/90 ,  C07D487/04 ,  A01N25/26 ,  A01P3/00

CPC分类号： A01N43/90 ,  A01N43/653 ,  A01N47/14 ,  A01N43/50 ,  A01N57/12 ,  A01N47/04 ,  A01N37/34 ,  A01N43/40 ,  A01N37/50 ,  A01N37/46 ,  A01N43/84 ,  A01N37/38 ,  A01N43/28 ,  A01N47/38 ,  A01N43/54 ,  A01N43/32 ,  A01N59/20 ,  A01N2300/00

摘要： Fungicidal mixtures, comprising as active components 1) a 5-chloro-6-phenyl-7-heterocyclylaminotriazolopyrimidine of the formula I, in which D together with the nitrogen atom forms a pyrrolidine, piperidine or azepine ring, which rings are unsubstituted or substituted by one or two methyl groups or by an ethyl, propyl or butyl group; and L is methyl, fluorine or chlorine; and 2) at least one active compound II selected from the following groups: A) azoles; B) strobilurins; C) acylalanines; D) amine derivatives; E) anilinopyrimidines; F) dicarboximides; G) cinnamides and analogs; H) antibiotics; K) dithiocarbamates; L) heterocyclic compounds according to the description; M) sulfur and copper fungicides; N) nitrophenyl derivatives; O) phenylpyrroles; P) sulfenic acid derivatives; Q) other fungicides according to the description; or R) growth retardants; in a synergistically effective amount, novel triazolopyrimidines, methods for controlling harmful fungi using compounds or mixtures of a compound I with an active compound of groups A) to R) and the use of the compounds I with the active compounds of groups A) to R) for preparing such mixtures, and also compositions comprising these compounds or mixtures.

摘要翻译： 包含作为活性组分的杀真菌混合物1）式I的5-氯-6-苯基-7-杂环基氨基三唑并嘧啶，其中D与氮原子一起形成吡咯烷，哌啶或氮杂环，该环是未取代的或被 一个或两个甲基或乙基，丙基或丁基; L为甲基，氟或氯; 和2）至少一种选自以下组的活性化合物II：A）唑类; B）嗜球果伞素 C）酰基丙氨酸; D）胺衍生物; E）苯胺嘧啶嘧啶; F）二羧酰亚胺; G）肉桂酸酯类似物; H）抗生素; K）二硫代氨基甲酸盐; L）杂环化合物; M）硫和铜杀菌剂; N）硝基苯基衍生物; O）苯基吡咯; P）亚磺酸衍生物; Q）其他杀菌剂根据说明; 或R）生长阻滞剂; 协同有效量的新型三唑并嘧啶，使用化合物或化合物I与A）至R）的活性化合物的混合物来控制有害真菌的方法以及将化合物I与基团A）至R的活性化合物 ），以及包含这些化合物或混合物的组合物。

公开(公告)号：US07550471B2

公开(公告)日：2009-06-23

申请号：US10531981

申请日：2003-11-04

申请人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Reinhard Stierl

发明人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Eberhard Ammermann ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Reinhard Stierl

IPC分类号： A01N43/90 ,  A61K31/519 ,  C07D487/00

CPC分类号： C07D487/04

摘要： The invention relates to 5-alkyl-7-aminotriazolopyrimidines of the formula (I) and to the salts thereof. In said formula substituents have the following meanings: R1 and R2 each is a hydrogen atom or a group of alkyl, alcenyl, haloalkyl, cycloalky, phenyl or naphtyle, saturated, unstaturated or aromatic heterocycle having from five to six members which contain from one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom, or R1 and R2 can from together with a connecting them nitrogen atom a cycle of 5 to 6 members containing from one to four nitrogen atoms or from one to three nitrogen atoms and one sulfur or oxygen atom, R3 is a cycloalkyl or bicycloalkyl group, R1, R2 and R3 can be substituted in conformity with a description, and X is an alkyl or alkyl halide group. The inventive methods and intermediary products necessary for producing said compounds, agents containing them and the use therefore for fighting against harmful mushroom are also disclosed.

摘要翻译： 本发明涉及式（I）的5-烷基-7-氨基三唑并嘧啶及其盐。 在所述式中，取代基具有以下含义：R 1和R 2各自为氢原子或具有5至6个成员的烷基，烯基，卤代烷基，环烷基，苯基或萘杂，饱和的，不饱和的或芳族杂环的基团， 四个氮原子或一个至三个氮原子和一个硫或氧原子，或者R 1和R 2可以连同它们的氮原子一起包含5至6个含有1-4个氮原子或1-3个氮原子的成员 和一个硫或氧原子，R 3为环烷基或双环烷基，R 1，R 2和R 3可以根据说明书进行取代，X为烷基或卤代烷基。 还公开了生产所述化合物所需的创造性方法和中间产物，含有它们的试剂和用于防止有害蘑菇的用途。

公开(公告)号：US07300908B2

公开(公告)日：2007-11-27

申请号：US10482216

申请日：2002-07-03

申请人： Bernd Müller ,  Hubert Sauter ,  Markus Gewehr ,  Wassilios Grammenos ,  Jordi Tormo i Blasco ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Frank Schieweck ,  Michael Rack ,  Gisela Lorenz ,  Siegfried Strathmann ,  Eberhard Ammermann ,  Reinhard Stierl

发明人： Bernd Müller ,  Hubert Sauter ,  Markus Gewehr ,  Wassilios Grammenos ,  Jordi Tormo i Blasco ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Ingo Rose ,  Peter Schäfer ,  Frank Schieweck ,  Michael Rack ,  Gisela Lorenz ,  Siegfried Strathmann ,  Eberhard Ammermann ,  Reinhard Stierl

IPC分类号： C07D487/04 ,  A01N43/48

CPC分类号： C07D487/04 ,  A01N43/90

摘要： Triazolopyrimidines of formula (I), wherein the index and substituents have the following meaning: n=0 or a whole number of 1-5; R=halogen, cyano, hydroxy, cyanate, alkyl, alkenyl, alkinyl, halogenalkyl, halogenalkenyl, alkoxy, alkenyloxy, alkinyloxy, halogenalkoxy, cycloalkyl, cycloalkenyl, cycloalkoxy, alkoxycarbonyl, alkenyloxycarbonyl, alkinyloxycarbonyl, aminocarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, alkoximinoalkyl, alkenyloximinocarbonyl, alkinyloximinoalkyl, alkylcarbonyl, alkenylcarbonyl, alkinylcarbonyl, cycloalkylcarbonyl or a five to ten membered saturated, partially unsaturated or aromatic heterocycle, containing one to four heteroatoms from the group O, N or S; R1=alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkenyl, phenyl, naphthyl or a five to ten membered saturated, partially unsaturated or aromatic heterocycle, containing one to four heteroatoms from the group O, N or S, R and/or R1 being able to be substituted according to the description; R2=alkyl, alkenyl or alkinyl which can be substituted by halogen, cyano, nitro, alkoxy or alkoxycarbonyl. The invention also relates to a method for the production of said compounds, agents containing same, and the use thereof in controlling noxious fungi

摘要翻译： 式（I）的三唑并嘧啶，其中指数和取代基具有以下含义：n = 0或整数1-5; 环烷氧基，烷氧基羰基，链烯氧基羰基，烷氧基羰基，氨基羰基，烷基氨基羰基，二烷基氨基羰基，肟基烷基，链烯基肟基羰基，烷氧基羰基，烷氧基羰基， 烷基羰基，链烯基羰基，炔基羰基，环烷基羰基或五至十元饱和，部分不饱和或芳族杂环，含有一至四个O，N或S基团的杂原子; R 1 =烷基，烯基，炔基，环烷基，环烯基，苯基，萘基或五至十元饱和，部分不饱和或芳族杂环，其含有一至四个O，N或S ，R和/或R 1能够根据描述进行取代; 可以被卤素，氰基，硝基，烷氧基或烷氧基羰基取代的烷基，烯基或炔基。 本发明还涉及生产所述化合物的方法，含有该化合物的试剂及其在控制有害真菌中的用途