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31.发明授权公开(公告)号：US08317719B2
公开(公告)日：2012-11-27
申请号：US13094597
申请日：2011-04-26
CPC分类号： A61B7/003 , A61N1/36514 , A61N1/36535
摘要： Adventitious lung sounds indicative of lung congestion are detected using an implantable sensor. The sensor is adapted to be positioned adjacent to a pulmonary system and to output signals indicative of lung sounds in response to pulmonary system activity. A controller receives the signals and processes the signals to detect the presence of adventitious lung sounds. A respiratory cycle sensor operating in conjunction with the lung-sound sensor enables classification of an adventitious lung sound according to its time occurrence within the respiratory cycle. Posture sensing in conjunction with lung-sound sensing provides valuable additional information as to the severity of the lung congestion.
摘要翻译： 使用植入式传感器检测到指示肺充血的不定肺声。 传感器适于邻近肺部系统定位，并响应于肺部系统活动而输出指示肺部声音的信号。 控制器接收信号并处理信号以检测不定肺声的存在。 与肺声传感器一起操作的呼吸循环传感器可以根据呼吸周期内的时间发生分类不定肺声。 结合肺部感觉的姿势感知提供了关于肺充血严重程度的有价值的附加信息。
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32.发明申请SYSTEM AND METHOD FOR RENAL ARTERY OCCLUSION DURING RENAL DENERVATION THERAPY 审中-公开肾功能衰竭治疗期间肾功能衰竭的系统与方法公开(公告)号：US20120232409A1
公开(公告)日：2012-09-13
申请号：US13327161
申请日：2011-12-15
IPC分类号： A61B5/0205 , A61B5/0215 , A61B5/027 , A61B5/026 , A61B5/021
CPC分类号： A61B18/20 , A61B5/021 , A61B5/024 , A61B5/026 , A61B5/201 , A61B18/02 , A61B18/0218 , A61B18/1206 , A61B18/1492 , A61B18/24 , A61B2018/0022 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00702 , A61B2018/00863 , A61B2018/0212 , A61B2018/1807 , A61N7/022 , A61N2005/0662
摘要： A catheter includes a flexible shaft having a length sufficient to access a patient's renal artery relative to a percutaneous access location. A treatment arrangement is provided at a distal end of the shaft and configured for deployment in the renal artery. The treatment arrangement includes an ablation arrangement configured to deliver renal denervation therapy. An occlusion arrangement is configured for deployment in the renal artery and for altering blood flow through the renal artery during or subsequent to renal denervation therapy delivery. A monitoring unit is configured for monitoring for a change in one or more physiologic parameters influenced by the renal denervation therapy. The monitoring unit is configured to produce data useful in assessing effectiveness of the renal denervation therapy based on the physiologic parameter monitoring.
摘要翻译： 导管包括具有足以相对于经皮进入位置访问患者的肾动脉的长度的柔性轴。 治疗装置设置在轴的远端并被配置为展开在肾动脉中。 治疗装置包括被配置为递送肾去神经治疗的消融装置。 闭塞装置构造成用于部署在肾动脉中并在肾去神经治疗递送期间或之后改变穿过肾动脉的血流。 监测单元被配置为监测受肾去神经治疗影响的一个或多个生理参数的变化。 监测单元被配置为产生用于评估基于生理参数监测的肾去神经治疗的有效性的数据。
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公开(公告)号：US08214034B2
公开(公告)日：2012-07-03
申请号：US11654942
申请日：2007-01-18
IPC分类号： A61N1/362
CPC分类号： A61N1/3627 , A61N1/3622 , A61N1/368
摘要： A device and method for multi chamber pacing a patient's heart having heart failure and intrinsic conduction, wherein ventricular tracking is used to pace the ventricle when the sinus rate exceeds a preset atrial maximum tracking rate. The ventricular tracking pacemaker increases the range of pacing the ventricle. The ventricular tracking minimizes the loss of ventricular pacing caused by intrinsic conduction when the sinus rate is below an atrial maximum tracking rate, and it induces a new ventricular pacing behavior for sinus rates above the atrial maximum tracking rate without any significant pacing hysteresis as the sinus rate returns towards the lower rate limit.
摘要翻译： 用于多室起搏具有心力衰竭和内在传导的患者心脏的装置和方法，其中当窦速率超过预设的心房最大跟踪率时，使用心室跟踪来对心室进行步调。 心室跟踪起搏器增加心室起搏的范围。 当窦速度低于心房最大跟踪率时，心室跟踪最小化由内在传导引起的心室起搏损失，并且其诱导窦速率高于心房最大跟踪率的新的心室起搏行为，而没有任何明显的起搏滞后作为窦 利率回到较低的汇率限制。
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34.发明申请SYSTEM AND METHOD FOR CORRELATION OF PATIENT HEALTH INFORMATION AND IMPLANT DEVICE DATA 有权用于相关患者健康信息和植入装置数据的系统和方法公开(公告)号：US20120165883A1
公开(公告)日：2012-06-28
申请号：US13411063
申请日：2012-03-02
CPC分类号： A61B5/4848 , A61B5/0006 , A61B5/0022 , A61B5/044 , A61B5/1118 , A61B5/7246 , A61B5/742 , A61B5/743 , A61B5/7445 , A61N1/3702 , A61N1/37252 , A61N1/3956 , A61N1/3993
摘要： A system and method for correlating health related data for display. The system includes a medical device recording data and a display producing device which correlates the data and simultaneously displays different types of data or displays two sets of the same type of data along with the circumstances at which the two sets of data were recorded. Such displays aid a physician in prescribing and ascertaining the efficacy of cardiac therapies.
摘要翻译： 将健康相关数据相关联以进行显示的系统和方法。 该系统包括记录数据的医疗设备和显示产生设备，其与数据相关并且同时显示不同类型的数据或显示两组相同类型的数据以及记录两组数据的情况。 这样的显示器有助于医师处方和确定心脏疗法的功效。
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35.发明授权System and method for correlation of patient health information and implant device data 有权用于患者健康信息和植入装置数据相关的系统和方法公开(公告)号：US08131351B2
公开(公告)日：2012-03-06
申请号：US12941377
申请日：2010-11-08
IPC分类号： A61B5/04
CPC分类号： A61B5/0006 , A61B5/044 , A61B5/743 , A61B5/7445 , G06F19/00
摘要： A system and method for correlating health related data for display. The system includes a medical device recording data and a display producing device which correlates the data and simultaneously displays different types of data or displays two sets of the same type of data along with the circumstances at which the two sets of data were recorded. Such displays aid a physician in prescribing and ascertaining the efficacy of cardiac therapies.
摘要翻译： 将健康相关数据相关联以进行显示的系统和方法。 该系统包括记录数据的医疗设备和显示产生设备，其与数据相关并且同时显示不同类型的数据或显示两组相同类型的数据以及记录两组数据的情况。 这样的显示器有助于医师处方和确定心脏疗法的功效。
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公开(公告)号：US20120041519A1
公开(公告)日：2012-02-16
申请号：US13282325
申请日：2011-10-26
IPC分类号： A61N1/36
CPC分类号： A61N1/36142 , A61N1/36114 , A61N1/36139 , A61N1/37
摘要： A neural stimulation system includes a safety control system that prevents delivery of neural stimulation pulses from causing potentially harmful effects. The neural stimulation pulses are delivered to one or more nerves to control the physiological functions regulated by the one or more nerves. Examples of such harmful effects include unintended effects in physiological functions associated with autonomic neural stimulation and nerve injuries caused by excessive delivery of the neural stimulation pulses.
摘要翻译： 神经刺激系统包括防止神经刺激脉冲传递引起潜在有害影响的安全控制系统。 将神经刺激脉冲输送到一个或多个神经以控制由一个或多个神经调节的生理功能。 这种有害影响的实例包括与神经刺激脉冲的过度递送引起的自主神经刺激和神经损伤相关的生理功能中的意想不到的影响。
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公开(公告)号：US08099165B2
公开(公告)日：2012-01-17
申请号：US13027681
申请日：2011-02-15
IPC分类号： A61N1/362
CPC分类号： A61N1/37247 , A61N1/3627 , A61N1/37235
摘要： A medical device programmer and a method of operation in which a first data value is received and used in the execution of one or more algorithms. One or more suggested pulse generator settings are calculated from the one or more algorithms based on the first data value, and the one or more suggested pulse generator settings are displayed on an interactive display screen of the medical device programmer. In one embodiment, the first data value is a duration interval of a QRS complex. From the duration interval, suggestions are made as to one or more ventricular chambers in which to provide pacing pulses. Additionally, pacing intervals for an AV delay are suggested based on measured P-R intervals, or pacing intervals for an LV offset are suggested based on a measured duration interval of a V-V-interval between a right ventricular event and a left ventricular event.
摘要翻译： 一种医疗设备编程器和操作方法，其中在执行一个或多个算法时接收并使用第一数据值。 基于第一数据值从一个或多个算法计算一个或多个建议的脉冲发生器设置，并且一个或多个建议的脉冲发生器设置显示在医疗设备编程器的交互式显示屏幕上。 在一个实施例中，第一数据值是QRS复数的持续时间间隔。 从持续时间间隔，建议一个或多个心室，其中提供起搏脉冲。 另外，基于测量的P-R间隔建议AV延迟的起搏间隔，或者基于右心室事件和左心室事件之间的V-V间隔的测量持续时间间隔来建议LV偏移的起搏间隔。
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公开(公告)号：US20110306850A1
公开(公告)日：2011-12-15
申请号：US13215592
申请日：2011-08-23
申请人： John D. Hatlestad , Quan Ni , Jeffrey E. Stahmann , Jesse Hartley , Qingsheng Zhu , Bruce H. KenKnight , Douglas R. Daum , Kent Lee
发明人： John D. Hatlestad , Quan Ni , Jeffrey E. Stahmann , Jesse Hartley , Qingsheng Zhu , Bruce H. KenKnight , Douglas R. Daum , Kent Lee
IPC分类号： A61B5/00
CPC分类号： A61B5/4815 , A61B5/0031 , A61B5/0205 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/0809 , A61B5/11 , A61B5/4528 , A61B5/4818 , A61N1/3621 , G06F19/00
摘要： A sleep quality assessment approach involves collecting data based on detected physiological or non-physiological patient conditions. At least one of detecting patient conditions and collecting data is performed using an implantable device. Sleep quality may be evaluated using the collected data by an implantable or patient-external sleep quality processor. One approach to sleep quality evaluation involves computing one or more summary metrics based on occurrences of movement disorders or breathing disorders during sleep.
摘要翻译： 睡眠质量评估方法包括基于检测到的生理或非生理性患者状况收集数据。 使用可植入装置执行检测患者状况和收集数据中的至少一个。 可以使用可植入或患者外部的睡眠质量处理器收集的数据来评估睡眠质量。 睡眠质量评估的一种方法包括基于睡眠期间的运动障碍或呼吸障碍的发生来计算一个或多个总结度量。
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39.发明授权Method and apparatus for treating irregular ventricular contractions such as during atrial arrhythmia 有权用于治疗不规则心室收缩的方法和装置，例如在心房心律失常期间公开(公告)号：US08064997B2
公开(公告)日：2011-11-22
申请号：US11423516
申请日：2006-06-12
IPC分类号： A61N1/362
CPC分类号： A61N1/3956 , A61N1/3622 , A61N1/395
摘要： A cardiac rhythm management system is capable of treating irregular ventricular heart contractions, such as during atrial tachyarrhythmias such as atrial fibrillation. A first indicated pacing interval is computed based at least partially on a most recent V-V interval duration between ventricular beats and a previous value of the first indicated pacing interval. Pacing therapy is provided based on either the first indicated pacing interval or also based on a second indicated pacing interval, such as a sensor-indicated pacing interval. A weighted averager such as an infinite impulse response (IIR) filter adjusts the first indicated pacing interval for sensed beats and differently adjusts the first indicated pacing interval for paced beats. The system regularizes ventricular rhythms by pacing the ventricle, but inhibits pacing when the ventricular rhythms are stable.
摘要翻译： 心律管理系统能够治疗不规则的心室心脏收缩，例如在房性快速性心律失常如心房颤动期间。 至少部分地基于心室搏动之间的最新V-V间期持续时间和第一个起搏间隔的先前值来计算第一个起搏间隔。 基于第一个起搏间隔或基于第二个起搏间隔（例如传感器指示的起搏间隔）来提供起搏疗法。 诸如无限脉冲响应（IIR）滤波器的加权平均器调节感测节拍的第一个起搏间隔，并且针对起搏节奏不同地调节第一个起搏间隔。 系统通过起搏心室使心室节律正常化，但是当心室节律稳定时，可抑制起搏。
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公开(公告)号：US08053740B2
公开(公告)日：2011-11-08
申请号：US13044003
申请日：2011-03-09
IPC分类号： G01T1/00
CPC分类号： A61N1/37 , A61N1/3718
摘要： An implantable medical apparatus comprises a solid state electronic circuit, an ionizing radiation exposure sensor, an ionizing radiation dose rate sensor, and a controller circuit. The ionizing radiation exposure sensor is configured to detect an exposure of the solid state electronic circuit to ionizing radiation, and generate an indication of a non-single-event-upset (non-SEU) effect to the solid state electronic circuit from the exposure to ionizing radiation, wherein the sensor comprises an accumulated ionizing radiation exposure sensor. The controller circuit is configured to blank the indication from the accumulated ionizing radiation exposure sensor when the radiation dose rate sensor indicates that flux ionizing radiation exceeds a flux ionizing radiation threshold.
摘要翻译： 一种可植入医疗装置，包括固态电子电路，电离辐射曝光传感器，电离辐射剂量率传感器和控制器电路。 电离辐射曝光传感器被配置为检测固态电子电路对电离辐射的曝光，并且产生对固态电子电路的非单事件不适（非SEU）效应的指示，从曝光到 电离辐射，其中所述传感器包括累积的电离辐射曝光传感器。 控制器电路被配置为当辐射剂量率传感器指示通量电离辐射超过通量电离辐射阈值时，从累积的电离辐射曝光传感器中消除指示。
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