Compounds and methods for immunotherapy and immunodiagnosis of prostate
cancer
    31.
    发明授权
    Compounds and methods for immunotherapy and immunodiagnosis of prostate cancer 失效
    前列腺癌的免疫治疗和免疫诊断的化合物和方法

    公开(公告)号:US6034218A

    公开(公告)日:2000-03-07

    申请号:US946026

    申请日:1997-10-07

    摘要: Compounds and methods for treating and diagnosing prostate cancer are provided. The inventive compounds include polypeptides containing at least a portion of a prostate protein. Vaccines and pharmaceutical compositions for immunotherapy of prostate cancer comprising such polypeptides or DNA molecules encoding such polypeptides are also provided. The inventive polypeptides may also be used to generate antibodies useful for the diagnosis and monitoring of prostate cancer. Nucleic acid sequences for preparing probes, primers, and polypeptides are also provided.

    摘要翻译: 提供了治疗和诊断前列腺癌的化合物和方法。 本发明化合物包括含有至少一部分前列腺蛋白质的多肽。 还提供了包含这样的多肽或编码这种多肽的DNA分子的前列腺癌的免疫治疗用疫苗和药物组合物。 本发明的多肽也可用于产生可用于诊断和监测前列腺癌的抗体。 还提供了用于制备探针,引物和多肽的核酸序列。

    Compositions and methods for ovarian cancer therapy and diagnosis
    32.
    发明授权
    Compositions and methods for ovarian cancer therapy and diagnosis 失效
    卵巢癌治疗和诊断的组成和方法

    公开(公告)号:US06468758B1

    公开(公告)日:2002-10-22

    申请号:US09397787

    申请日:1999-09-16

    IPC分类号: G01N33574

    CPC分类号: C12Q1/6886

    摘要: Compositions and methods for the therapy and diagnosis of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions thereof, polynucleotides that encode such portions or antibodies or immune system cells specific for such proteins. Such compositions may be used, for example, for the prevention and treatment of diseases such as ovarian cancer. Methods are further provided for identifying tumor antigens that are secreted from ovarian carcinomas and/or other tumors. Polypeptides and polynucleotides as provided herein may further be used for the diagnosis and monitoring of ovarian cancer.

    摘要翻译: 公开了用于治疗和诊断癌症的组合物和方法,例如卵巢癌。 组合物可以包含一种或多种卵巢癌蛋白,其免疫原性部分,编码这种部分的多核苷酸或对这些蛋白质特异的抗体或免疫系统细胞。 这样的组合物可用于例如预防和治疗诸如卵巢癌的疾病。 还提供了用于鉴定从卵巢癌和/或其他肿瘤分泌的肿瘤抗原的方法。 本文提供的多肽和多核苷酸还可用于诊断和监测卵巢癌。

    Compositions and methods for therapy and diagnosis of ovarian cancer
    33.
    发明授权
    Compositions and methods for therapy and diagnosis of ovarian cancer 失效
    卵巢癌的治疗和诊断的组成和方法

    公开(公告)号:US06488931B1

    公开(公告)日:2002-12-03

    申请号:US09338933

    申请日:1999-06-23

    IPC分类号: A61K3900

    摘要: Compositions and methods for the therapy of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions thereof, polynucleotides that encode such portions or antibodies or immune system cells specific for such proteins. Such compositions may be used, for example, for the prevention and treatment of diseases such as ovarian cancer. Methods are further provided for identifying tumor antigens that are secreted from ovarian carcinomas and/or other tumors.

    摘要翻译: 公开了用于治疗癌症的组合物和方法,例如卵巢癌。 组合物可以包含一种或多种卵巢癌蛋白,其免疫原性部分,编码这种部分的多核苷酸或对这些蛋白质特异的抗体或免疫系统细胞。 这样的组合物可用于例如预防和治疗诸如卵巢癌的疾病。 还提供了用于鉴定从卵巢癌和/或其他肿瘤分泌的肿瘤抗原的方法。

    Compositions and methods for therapy and diagnosis of ovarian cancer
    34.
    发明授权
    Compositions and methods for therapy and diagnosis of ovarian cancer 失效
    卵巢癌的治疗和诊断的组成和方法

    公开(公告)号:US06468546B1

    公开(公告)日:2002-10-22

    申请号:US09404879

    申请日:1999-09-24

    IPC分类号: A61K3900

    摘要: Compositions and methods for the therapy and diagnosis of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions thereof, polynucleotides that encode such portions or antibodies or immune system cells specific for such proteins. Such compositions may be used, for example, for the prevention and treatment of diseases such as ovarian cancer. Methods are further provided for identifying tumor antigens that are secreted from ovarian carcinomas and/or other tumors. Polypeptides and polynucleotides as provided herein may further be used for the diagnosis and monitoring of ovarian cancer.

    摘要翻译: 公开了用于治疗和诊断癌症的组合物和方法,例如卵巢癌。 组合物可以包含一种或多种卵巢癌蛋白,其免疫原性部分,编码这种部分的多核苷酸或对这些蛋白质特异的抗体或免疫系统细胞。 这样的组合物可用于例如预防和治疗诸如卵巢癌的疾病。 还提供了用于鉴定从卵巢癌和/或其他肿瘤分泌的肿瘤抗原的方法。 本文提供的多肽和多核苷酸还可用于诊断和监测卵巢癌。

    Compositions and methods for the therapy and diagnosis of ovarian cancer
    35.
    发明授权
    Compositions and methods for the therapy and diagnosis of ovarian cancer 有权
    卵巢癌的治疗和诊断的组成和方法

    公开(公告)号:US06962980B2

    公开(公告)日:2005-11-08

    申请号:US09827271

    申请日:2001-04-04

    摘要: Compositions and methods for the therapy and diagnosis of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions thereof, polynucleotides that encode such portions or antibodies or immune system cells specific for such proteins. Such compositions may be used, for example, for the prevention and treatment of diseases such as ovarian cancer. Methods are further provided for identifying tumor antigens that are secreted from ovarian carcinomas and/or other tumors. Polypeptides and polynucleotides as provided herein may further be used for the diagnosis and monitoring of ovarian cancer.

    摘要翻译: 公开了用于治疗和诊断癌症的组合物和方法,例如卵巢癌。 组合物可以包含一种或多种卵巢癌蛋白,其免疫原性部分,编码这种部分的多核苷酸或对这些蛋白质特异的抗体或免疫系统细胞。 这样的组合物可用于例如预防和治疗诸如卵巢癌的疾病。 还提供了用于鉴定从卵巢癌和/或其他肿瘤分泌的肿瘤抗原的方法。 本文提供的多肽和多核苷酸还可用于诊断和监测卵巢癌。

    Compositions and methods for therapy of ovarian cancer
    36.
    发明授权
    Compositions and methods for therapy of ovarian cancer 失效
    用于治疗卵巢癌的组合物和方法

    公开(公告)号:US06670463B1

    公开(公告)日:2003-12-30

    申请号:US09216003

    申请日:1998-12-17

    IPC分类号: C07H2104

    摘要: Compositions and methods for the therapy of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions thereof, polynucleotides that encode such portions or antibodies or immune system cells specific for such proteins. Such compositions may be used, for example, for the prevention and treatment of diseases such as ovarian cancer. Methods are further provided for identifying tumor antigens that are secreted from ovarian carcinomas and/or other tumors.

    摘要翻译: 公开了用于治疗癌症的组合物和方法,例如卵巢癌。 组合物可以包含一种或多种卵巢癌蛋白,其免疫原性部分,编码这种部分的多核苷酸或对这些蛋白质特异的抗体或免疫系统细胞。 这样的组合物可用于例如预防和治疗诸如卵巢癌的疾病。 还提供了用于鉴定从卵巢癌和/或其他肿瘤分泌的肿瘤抗原的方法。

    Compositions and methods for diagnosis of ovarian cancer
    37.
    发明授权
    Compositions and methods for diagnosis of ovarian cancer 有权
    卵巢癌诊断的组成和方法

    公开(公告)号:US06528253B1

    公开(公告)日:2003-03-04

    申请号:US09215681

    申请日:1998-12-17

    IPC分类号: C12Q168

    摘要: Compositions and methods for the diagnosis of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions thereof or polynucleotides that encode such portions. Such compositions may be used, for example, for the detecting and monitoring diseases such as ovarian cancer.

    摘要翻译: 公开了用于诊断癌症的组合物和方法,例如卵巢癌。 组合物可以包含一种或多种卵巢癌蛋白,其免疫原性部分或编码这些部分的多核苷酸。 这样的组合物可用于例如检测和监测诸如卵巢癌之类的疾病。