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38 条记录 (耗时 0.061 秒)

    Driving apparatus
    32.
    发明授权
    Driving apparatus 有权
    驱动装置

    公开(公告)号：US07791247B2

    公开(公告)日：2010-09-07

    申请号：US11719497

    申请日：2006-07-20

    申请人： Norihiko Kikuchi ,  Nobuyuki Hirose

    发明人： Norihiko Kikuchi ,  Nobuyuki Hirose

    IPC分类号： H01L41/00

    CPC分类号： H02N2/062 ,  G02B7/102 ,  G03B3/10 ,  H02N2/025

    摘要： An automatic focus camera Unit 10, comprises; a piezoelectric element 13a; a driving shaft 13b to be driven by the piezoelectric element 13a; a moving unit 13c to be moved with respect to the driving shaft 13b by a friction force caused by the driving shaft 13b; a microcomputer unit 24 for controlling power supply to the piezoelectric element 13a, and in which the microcomputer unit 24 assumes a preprocessing mode of calculating an amount of adjustment for a power supply time in accordance with a moving direction of the moving unit 13c, and a movement controlling mode of adjusting the supply time and controlling power supply based on the moving direction and the amount of adjustment. In the preprocessing mode, the moving unit 13c is controlled based on the detecting result of the base end sensor 15 and moved in forward and backward directions using the base end position 15a as a reference point, and the amount of adjustment is calculated based on the supply time for which power is supplied while the moving unit 13c is moved in the forward direction and the supply time for which power is supplied while the moving unit 13c is moved in backward direction.

    摘要翻译： 自动对焦摄像机单元10包括： 压电元件13a; 由压电元件13a驱动的驱动轴13b; 通过由驱动轴13b产生的摩擦力相对于驱动轴13b移动的移动单元13c; 用于控制对压电元件13a的供电的微计算机单元24，其中微型计算机单元24采取根据移动单元13c的移动方向计算供电时间的调整量的预处理模式，以及 运动控制模式，根据移动方向和调整量调节供电时间和控制电源。 在预处理模式中，基于基端传感器15的检测结果，使用基端位置15a作为基准点，在前后方向上移动移动单元13c，并且基于 在移动单元13c沿向前方向移动的同时，在移动单元13c向后移动的同时，供应电力的供给时间和供给时间。

    PYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATE IN PRODUCING THE SAME
    34.
    发明申请
    PYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATE IN PRODUCING THE SAME 失效
    吡唑衍生物，含有该药物的药物组合物，在其生产中的药物用途及其中间体

    公开(公告)号：US20100029919A1

    公开(公告)日：2010-02-04

    申请号：US12534452

    申请日：2009-08-03

    申请人： Hideki Fujikura ,  Norihiko Kikuchi ,  Shigeki Tazawa ,  Tokuhisa Yamato ,  Masayuki Isaji

    发明人： Hideki Fujikura ,  Norihiko Kikuchi ,  Shigeki Tazawa ,  Tokuhisa Yamato ,  Masayuki Isaji

    IPC分类号： C07H17/02

    CPC分类号： C07D405/04 ,  A61K31/7056 ,  C07D231/20 ,  C07D401/04 ,  C07D409/04 ,  C07H17/02 ,  Y10S514/866

    摘要： The present invention provides pyrazole derivatives represented by the general formula: wherein R1 represents H, an optionally substituted C1-6 alkyl group etc.; one of Q and T represents a group selected from the following groups: , and the other represents —(CH2)n—Ar wherein Ar represents an optionally substituted C6-10 aryl group or an optionally substituted C1-9 heteroaryl group; and n represents an integral number from 0 to 2, an optionally substituted C1-6 alkoxyl group, an optionally substituted amino group, an optionally substituted C2-9 heterocycloalkyl group or an optionally substituted heterocycle-fused phenyl group; R represents an optionally substituted C3-8 cycloalkyl group, an optionally substituted C6-10 aryl group etc., pharmaceutically acceptable salts thereof or prodrugs thereof, which exhibit an excellent inhibitory activity in human 1,5-anhydroglucitol/fructose/mannose transporter and are useful as agents for the prevention, inhibition of progression or treatment of a disease associated with the excess uptake of at least a kind of carbohydrates selected from glucose, fructose and mannose or a disease associated with hyperglycemia (e.g., diabetic complications, diabetes, etc.), and pharmaceutical compositions comprising the same, pharmaceutical uses thereof, and intermediates for production thereof.

    摘要翻译： 本发明提供由以下通式表示的吡唑衍生物：其中R1表示H，任选取代的C 1-6烷基等; Q和T中的一个表示选自以下基团的基团：另一个表示 - （CH 2）n -Ar，其中Ar表示任选取代的C 6-10芳基或任选取代的C 1-8杂芳基; n表示0〜2的整数，可以具有取代基的C 1-6烷氧基，可以具有取代基的氨基，可以具有取代基的C2-9杂环烷基或任意取代的杂环稠合苯基; R表示任选取代的C 3-8环烷基，任选取代的C 6-10芳基等，其药学上可接受的盐或其前体药物，其在人1,5-脱水葡萄糖醇/果糖/甘露糖转运蛋白中表现出优异的抑制活性， 可用作预防，抑制与选自葡萄糖，果糖和甘露糖中的至少一种碳水化合物或与高血糖相关疾病（例如，糖尿病并发症，糖尿病等）的过量摄取相关疾病进展或治疗的药剂。 ），以及包含该药物组合物的药物组合物，其药学用途及其生产用中间体。

    Benzimidazole derivatives and medical uses thereof
    35.
    发明授权
    Benzimidazole derivatives and medical uses thereof 失效
    苯并咪唑衍生物及其医疗用途

    公开(公告)号：US07547680B2

    公开(公告)日：2009-06-16

    申请号：US11473957

    申请日：2006-06-23

    申请人： Norihiko Kikuchi ,  Yoshinori Nonaka ,  Kazuya Tatani ,  Masahiro Hiratochi ,  Yu Kuramochi ,  Masayuki Isaji ,  Kazuo Shimizu ,  Takashi Miyagi

    发明人： Norihiko Kikuchi ,  Yoshinori Nonaka ,  Kazuya Tatani ,  Masahiro Hiratochi ,  Yu Kuramochi ,  Masayuki Isaji ,  Kazuo Shimizu ,  Takashi Miyagi

    IPC分类号： A01N43/04 ,  A61K31/70

    CPC分类号： C07H19/052

    摘要： The present invention provides benzimidazole derivatives represented by the following formula (I) or pharmaceutically acceptable salts thereof, or prodrugs thereof, which exert an inhibitory activity on sodium-dependent nucleoside transporter 2 and are useful for a disease associated with an abnormality of plasma uric acid level. The compounds of the present invention are useful for the prevention or treatment of gout, hyperuricemia, urinary lithiasis, hyperuricemic nephropathy or the like.In the formula, n is 1 or 2; R1 and R2 are H, a halogen atom, cyano group, optionally substituted alkyl group, optionally substituted aryl group or the like; R3 is H, a halogen atom, optionally substituted alkyl group or the like; R4 and R5 are H, a halogen atom, OH or the like; and R6 and RX are H or OH: RY is F or OH.

    摘要翻译： 本发明提供由下式（I）表示的苯并咪唑衍生物或其药学上可接受的盐或其前药，其对钠依赖性核苷转运蛋白2具有抑制活性，并且可用于与血浆尿酸异常有关的疾病 水平。 本发明的化合物可用于预防或治疗痛风，高尿酸血症，尿结石病，高尿酸性肾病等。 在该式中，n为1或2; R 1和R 2是H，卤素原子，氰基，任选取代的烷基，任选取代的芳基等; R3是H，卤素原子，任选取代的烷基等; R 4和R 5是H，卤素原子，OH等; R6和RX是H或OH：RY是F或OH。

    DRIVING APPARATUS
    36.
    发明申请
    DRIVING APPARATUS 有权
    驱动装置

    公开(公告)号：US20090146602A1

    公开(公告)日：2009-06-11

    申请号：US11719497

    申请日：2006-07-20

    申请人： Norihiko Kikuchi ,  Nobuyuki Hirose

    发明人： Norihiko Kikuchi ,  Nobuyuki Hirose

    IPC分类号： G05G5/04 ,  H02N2/06

    CPC分类号： H02N2/062 ,  G02B7/102 ,  G03B3/10 ,  H02N2/025

    摘要： [Problems] It is therefore an object of the present invention to provide a driving apparatus which can be reduced in the number of complete parts in comparison with the conventional driving apparatus.[Means for Solving Problems] An automatic focus camera unit 10, comprises; a piezoelectric element 13a; a driving shaft 13b to be driven by the piezoelectric element 13a; a moving unit 13c to be moved with respect to the driving shaft 13b by a friction force caused by the driving shaft 13b; a microcomputer unit 24 for controlling power supply to the piezoelectric element 13a, and in which the microcomputer unit 24 assumes a preprocessing mode of calculating an amount of adjustment for a power supply time in accordance with a moving direction of the moving unit 13c, and a movement controlling mode of adjusting the supply time and controlling power supply based on the moving direction and the amount of adjustment. In the preprocessing mode, the moving unit 13c is controlled based on the detecting result of the base end sensor 15 and moved in forward and backward directions using the base end position 15a as a reference point, and the amount of adjustment is calculated based on the supply time for which power is supplied while the moving unit 13c is moved in the forward direction and the supply time for which power is supplied while the moving unit 13c is moved in backward direction.

    摘要翻译： 发明内容因此，本发明的目的在于提供一种驱动装置，与传统的驱动装置相比，能够减少完整部件的数量。 解决问题的手段自动聚焦照相机单元10包括： 压电元件13a; 由压电元件13a驱动的驱动轴13b; 通过由驱动轴13b产生的摩擦力相对于驱动轴13b移动的移动单元13c; 用于控制对压电元件13a的供电的微计算机单元24，其中微型计算机单元24采取根据移动单元13c的移动方向计算供电时间的调整量的预处理模式，以及 运动控制模式，根据移动方向和调整量调节供电时间和控制电源。 在预处理模式中，基于基端传感器15的检测结果，使用基端位置15a作为基准点，在前后方向上移动移动单元13c，并且基于 在移动单元13c沿向前方向移动的同时，在移动单元13c向后移动的同时，供应电力的供给时间和供给时间。

    Pyrazole derivative, drug composition containing the same and production intermediate therefor
    37.
    发明申请
    Pyrazole derivative, drug composition containing the same and production intermediate therefor 失效
    吡唑衍生物，含有它们的药物组合物及其制备中间体

    公开(公告)号：US20070060531A1

    公开(公告)日：2007-03-15

    申请号：US10561217

    申请日：2004-06-15

    申请人： Norihiko Kikuchi ,  Hideki Fujikura ,  Shigeki Tazawa ,  Tokuhisa Yamato ,  Masayuki Isaji

    发明人： Norihiko Kikuchi ,  Hideki Fujikura ,  Shigeki Tazawa ,  Tokuhisa Yamato ,  Masayuki Isaji

    IPC分类号： A61K31/7052 ,  C07H15/00

    CPC分类号： C07D231/32 ,  A61K31/7056 ,  A61K31/706 ,  C07D231/52 ,  Y10S514/866

    摘要： The present invention provides pyrazole derivatives represented by the general formula: wherein R1 represents H, an optionally substituted C1-6 alkyl, etc.; one of Q and T represents a group selected from the following: , and the other represents -Z-Ar wherein Z represents —O—, —S—, etc.; Ar represents an optionally substituted C6-10 aryl, etc.; R represents an optionally substituted C3-8 cycloalkyl, an optionally substituted C6-10 aryl, etc., pharmaceutically acceptable salts thereof, and prodrugs thereof, which exhibit an excellent inhibitory activity in human sodium/glucose cotransporter (SGLT) and are useful as agents for the prevention, inhibition of progression or treatment of a disease associated with the excess uptake of at least a kind of carbohydrates selected from glucose, fructose and mannose (diabetes, postprandial hyperglycemia, impaired glucose tolerance, diabetic complications, etc.), and pharmaceutical compositions containing the same, medicinal uses thereof and intermediates for production therefor.

    摘要翻译： 本发明提供由以下通式表示的吡唑衍生物：其中R 1表示H，任选取代的C 1-6烷基等; Q和T中的一个表示选自以下的基团：另一个表示-Z-Ar，其中Z表示-O-，-S-等; Ar表示任选取代的C 6-10芳基等; R表示任选取代的C 3-8环烷基，任选取代的C 6-10芳基等，其药学上可接受的盐及其前药，其表现出优异的 在人钠/葡萄糖协同转运蛋白（SGLT）中的抑制活性，并且可用作预防，抑制与选自葡萄糖，果糖和甘露糖中的至少一种碳水化合物的过量摄取相关的疾病的进展或治疗的药剂（糖尿病， 餐后高血糖，葡萄糖耐量降低，糖尿病并发症等），含有该组合物的药物组合物，其医药用途和用于其生产的中间体。

    Method and apparatus for producing mold
    38.
    发明授权
    Method and apparatus for producing mold 有权
    生产模具的方法和设备

    公开(公告)号：US06953077B2

    公开(公告)日：2005-10-11

    申请号：US10009903

    申请日：2001-05-10

    申请人： Yutaka Miyamoto ,  Norihiko Kikuchi

    发明人： Yutaka Miyamoto ,  Norihiko Kikuchi

    IPC分类号： B21D37/20 ,  B22C9/00

    CPC分类号： B21D37/20

    摘要： A method and an apparatus for machining a mold material to produce a mold. By casting based on a cast mold model (15), a mold material (20) is produced in a form having a work margin. Thereafter, a shape of the mold material (20) is measured by a measuring device (16), and measurement data and an envelope model (M2) generated based on the measurement data are stored in a storage unit (12A) of a computer (12). Thereafter, a mold model (M1) based on mold design data and an envelope model (M2) are displayed on a display unit (12C), and the envelope model (M2) is linearly moved in direction of three axes X, Y and Z orthogonal to one another respectively and rotated around the three axes to bring a product forming plane (M2B) of the envelope model (M2) into close proximity of a product forming plane (M1B) of the mold model (M1). Thereby, a state in which a work amount of a product forming plane (20B) of the mold material (20) is reduced is found, and a reference plane (20A) and a product forming plane (20B) of the mold material 20 are cut by a mold working machine (18) controlled by the computer (12).

    摘要翻译： 一种用于加工模具材料以制造模具的方法和装置。 通过基于铸造模型（15）的铸造，以具有工作余量的形式制造模具材料（20）。 此后，通过测量装置（16）测量模具材料（20）的形状，并且将基于测量数据生成的测量数据和包络模型（M 2）存储在存储单元（12A）中 电脑（12）。 此后，在显示单元（12C）上显示基于模具设计数据和包络模型（M 2）的模具模型（M 1），并且包络模型（M2）在三个轴线X的方向上线性移动 ，Y和Z分别彼此正交并围绕三个轴线旋转，以使包络模型（M2）的产品形成平面（M 2 B）紧邻模具的产品形成平面（M 1 B） 型号（M 1）。 因此，发现了模具材料（20）的产品形成平面（20B）的加工量减少的状态，并且模具的参考平面（20A）和产品形成平面（20B） 材料20由计算机（12）控制的模具加工机（18）切割。