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    PERCUTANEOUS CATHETER DIRECTED INTRAVASCULAR OCCLUSION DEVICE
    33.
    发明申请
    PERCUTANEOUS CATHETER DIRECTED INTRAVASCULAR OCCLUSION DEVICE 有权
    PERCUTANEOUS CATHETER指导性血管内装置

    公开(公告)号：US20090187214A1

    公开(公告)日：2009-07-23

    申请号：US12235059

    申请日：2008-09-22

    申请人： Kurt Amplatz ,  Xiaoping Gu ,  John C. Oslund

    发明人： Kurt Amplatz ,  Xiaoping Gu ,  John C. Oslund

    IPC分类号： A61B17/08

    CPC分类号： A61B17/0057 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00601 ,  A61B2017/00606 ,  A61B2017/00867 ,  A61B2017/00911 ,  A61B2090/3933

    摘要： Embodiments of the present invention provide medical devices and methods for occluding a target site are provided. For example, the medical device may include a tubular member having proximal and distal ends and at least one plane of occlusion. The at least one plane of occlusion may be configured to substantially occlude the patent ductus arteriosus in less than about 1 minute. In addition or alternatively, the tubular member may consist of a single layer of material and be configured to be constrained within a catheter having an outer diameter of less than about 4 French for percutaneous delivery to the patent ductus arteriosus.

    摘要翻译： 本发明的实施例提供了用于闭塞目标部位的医疗装置和方法。 例如，医疗装置可以包括具有近端和远端以及至少一个闭塞平面的管状构件。 所述至少一个闭塞平面可被构造成在小于约1分钟内基本封闭动脉导管未闭。 另外或替代地，管状构件可以由单层材料构成，并且被构造成被限制在具有小于约4 French的外径的导管内，用于经皮输送到动脉导管未闭。

    Intravascular deliverable stent for reinforcement of vascular abnormalities
    34.
    发明申请
    Intravascular deliverable stent for reinforcement of vascular abnormalities 有权
    血管内输送支架用于加强血管异常

    公开(公告)号：US20070168019A1

    公开(公告)日：2007-07-19

    申请号：US11654288

    申请日：2007-01-17

    申请人： Kurt Amplatz ,  John C. Oslund ,  Patrick Russo ,  Xiaoping Gu

    发明人： Kurt Amplatz ,  John C. Oslund ,  Patrick Russo ,  Xiaoping Gu

    IPC分类号： A61F2/06

    CPC分类号： A61F2/82 ,  A61F2/07 ,  A61F2/852 ,  A61F2/90 ,  A61F2002/075 ,  A61F2002/823 ,  A61F2210/0014 ,  A61F2210/0076 ,  A61F2220/0008 ,  A61F2220/0041 ,  A61F2220/0075 ,  A61F2250/0015 ,  A61F2250/0023 ,  A61F2250/0037

    摘要： A catheter deliverable stent/graft especially designed to be used in a minimally invasive surgical procedure for treating a variety of vascular conditions such as aneurysms, stenotic lesions and saphenous vein grafts, comprises an innermost tubular structure and at least one further tubular member in coaxial arrangement. In one embodiment, the innermost tubular structure is of a length (L1) and is formed by braiding a relatively few strands of highly elastic metallic alloy. The pick and pitch of the braid are such as to provide relative large fenestrations in the tubular wall that permit blood flow through the wall and provide the primary radial support structure. A portion of the innermost tubular structure of a length L1 is surrounded by a further braided tubular structure having relatively many strands that substantially inhibit blood flow through the fenestrations of the innermost tubular structure. The composite structure can be stretched to reduce the outer diameter of the stent/graft, allowing it to be drawn into a lumen of a delivery catheter. The catheter can then be advanced through the vascular system to the site of treatment and then released, allowing it to self-expand against the vessel wall. Various optional embodiments are disclosed that allow one skilled in the art to tailor the design to the specific application.

    摘要翻译： 特别设计用于治疗各种血管病变如动脉瘤，狭窄病变和隐静脉移植物的微创外科手术中的导管可输送支架/移植物包括最内管状结构和至少一个同轴布置的另外的管状构件 。 在一个实施例中，最内管状结构具有长度（L L1），并且通过编织相对较少数量的高弹性金属合金而形成。 编织物的拣选和间距是在管状壁中提供允许血液流过壁并提供初级径向支撑结构的相对较大的开窗。 长度为L 1的最内管状结构的一部分由具有相当多的股线的进一步的编织管状结构包围，其基本上抑制通过最内管状结构的开窗的血液流动。 复合结构可被拉伸以减小支架/移植物的外径，使其能够被拉入输送导管的内腔。 导管然后可以通过血管系统前进到治疗部位，然后释放，允许其自我扩张抵靠血管壁。 公开了各种可选实施例，其允许本领域技术人员根据具体应用来定制设计。

    System for the controlled delivery of stents and grafts
    35.
    发明申请
    System for the controlled delivery of stents and grafts 审中-公开
    用于支架和移植物受控输送的系统

    公开(公告)号：US20060253184A1

    公开(公告)日：2006-11-09

    申请号：US11121386

    申请日：2005-05-04

    申请人： Kurt Amplatz

    发明人： Kurt Amplatz

    IPC分类号： A61F2/06

    CPC分类号： A61F2/95

    摘要： The present invention provides a delivery mechanism for percutaneously routing a stent or graft through the vascular system and procedures for addressing an aneurysm or an otherwise damaged vessel. The delivery system includes an outer tubular guide catheter 20, an inner tubular delivery (pusher) catheter 14 coaxially disposed and slidable relative to the outer guide catheter and an elongated flexible wire or cable 26 that is coaxially insertable through the lumen of the inner tubular catheter and that has a frusto-conical bead affixed at the distal end thereof which is sized to at least partially fit within the lumen of the inner pusher catheter when a proximally directed tension force is applied between the elongated flexible wire or cable 26 with respect to the pusher catheter 14. By inserting a compressed coil spring between a proximal end portion of the pusher catheter 14 and the proximal end portion of the cable 26, the requisite clamping force is maintained to secure the stent or graft to the distal end of the pusher catheter until the compression spring force is removed. With the stent or graft clamped to the distal end of the inner pusher catheter, it can be drawn within the lumen of the outer guide catheter for delivery therewith to the target site.

    摘要翻译： 本发明提供一种用于经皮穿透支架或移植物穿过血管系统的递送机制以及用于解决动脉瘤或另外受损的血管的程序。 输送系统包括外部管状引导导管20，相对于外部引导导管同轴地设置和滑动的内部管状输送（推动器）导管14和可同轴插入穿过内部管状导管的内腔的细长柔性线或电缆26 并且其具有固定在其远端处的截头圆锥形珠，其尺寸设计成至少部分地配合在内部推动器导管的内腔内时，当在细长柔性线或电缆26之间相对于 推动导管14.通过在推动器导管14的近端部分和电缆26的近端部分之间插入压缩的螺旋弹簧，维持必要的夹持力以将支架或移植物固定到推动导管的远端 直到压缩弹簧力被去除。 当将支架或移植物夹持到内部推动器导管的远端时，其可以在外导向导管的内腔中被拉伸以便与其一起输送到目标部位。

    Alignment member for delivering a non-symmetric device with a predefined orientation
    36.
    发明授权
    Alignment member for delivering a non-symmetric device with a predefined orientation 有权
    用于递送具有预定义取向的非对称装置的对准构件

    公开(公告)号：US06334864B1

    公开(公告)日：2002-01-01

    申请号：US09572649

    申请日：2000-05-17

    申请人： Kurt Amplatz ,  Michael Afremov

    发明人： Kurt Amplatz ,  Michael Afremov

    IPC分类号： A61B1700

    CPC分类号： A61B17/12022 ,  A61B17/12109 ,  A61B17/12172 ,  A61B2017/00455 ,  A61B2017/00592 ,  A61B2017/00606 ,  A61B2017/00623 ,  A61B2017/12095

    摘要： A device and method for delivering an object within a patient, wherein the object is delivered in a preferred orientation relative to the delivery site of the patient. The delivery device has an alignment member that allows the object to be delivered intravascularly to the delivery site of the patient, wherein the object is delivered in a pre-determined orientation. The object may, for example, be non-symmetric or include a configuration that requires delivery to the site in only one suitable orientation relative to the delivery site. Such objects may be used, for example, to treat certain defects or injuries in vessels or organs within a patient's body.

    摘要翻译： 一种用于递送患者体内的物体的装置和方法，其中所述物体相对于患者的递送部位以优选的方向递送。 递送装置具有对准构件，其允许物体血管内输送到患者的输送部位，其中物体以预定方向递送。 例如，该对象可以是非对称的，或者包括需要相对于递送部位仅以一个合适方向递送到该站点的配置。 这样的物体可以用于例如治疗患者体内的血管或器官中的某些缺陷或损伤。

    Sizing catheter for measuring cardiovascular structures
    37.
    发明授权
    Sizing catheter for measuring cardiovascular structures 有权
    用于测量心血管结构的尺寸导管

    公开(公告)号：US06210338B1

    公开(公告)日：2001-04-03

    申请号：US09450240

    申请日：1999-11-29

    申请人： Michael Afremov ,  Kurt Amplatz

    发明人： Michael Afremov ,  Kurt Amplatz

    IPC分类号： A61B502

    CPC分类号： A61B5/1076 ,  A61M25/10

    摘要： A sizing catheter and method of measuring a preselected internal opening within a patient to provide a rapid and precise determination of first and second stretched diameters of the preselected internal opening. The sizing catheter includes a dilation balloon constructed of a thin expandable plastic, which is inflatable and is utilized to determine a size of the preselected opening. The dilation balloon is inflated to an inflation threshold wherein the dilation balloon deforms about the preselected opening and the size of the dilation balloon adjacent the preselected opening approximates the first stretched diameter of the preselected opening. The sizing catheter and method may be utilized to determine an appropriate sized device to be positioned within the preselected opening.

    摘要翻译： 尺寸导管和测量患者内的预选内部开口的方法，以快速和精确地确定预先选择的内部开口的第一和第二拉伸直径。 定径导管包括由薄的可膨胀塑料构成的扩张气囊，其是可充气的并且用于确定预选开口的尺寸。 膨胀气囊膨胀至充气阈值，其中扩张气囊围绕预选开口变形，并且与预选开口相邻的扩张球囊的尺寸近似于预选开口的第一拉伸直径。 定径导管和方法可以用于确定要放置在预选开口内的合适尺寸的装置。

    Medical introducer and valve assembly
    38.
    发明授权
    Medical introducer and valve assembly 失效
    医疗导引器和阀组件

    公开(公告)号：US5098393A

    公开(公告)日：1992-03-24

    申请号：US200662

    申请日：1988-05-31

    申请人： Kurt Amplatz ,  Frank Kotula

    发明人： Kurt Amplatz ,  Frank Kotula

    IPC分类号： A61M25/06 ,  A61M39/06

    CPC分类号： A61M25/0606 ,  A61M39/0606 ,  A61M2025/0687 ,  A61M2039/062 ,  A61M2039/0633 ,  A61M2039/0686

    摘要： A medical catheter introducer and hemostasis valve assembly consists of a sheath having an elongated tube defining a conduit, a housing disposed at the proximal end of the sheath and further defining a conduit and an orifice, and a flexible elongated dilator sized for insertion through the hub and sheath conduit. The dilator has a tapered distal tip end and defines an axial conduit and an annular ridge having distally- and proximally-directed inclined surfaces. The sheath, when assembled with the dilator, has its distal end immediately adjacent the proximally-directed inclined surface of the ridge. A hemostasis valve for sealing the conduit is disposed in alignment with the conduit, and defines an aperture for passage of dilator and ridge therethrough in sealing engagement, into the conduit, and seals when the dilator is removed. The valve has a housing defining an orifice of a first diameter, and a valve element of a second diameter, greater than the first diameter. The valve is disposed within the orifice and is subject to externally-applied, radially directed forces that cause the valve to assume a dome-shape formation, with a convex surface disposed against the pressure of fluids within the body. As the introducer assembly is introduced into a body over a guidewire extending via a puncture opening into a vessel, the dilator and sheath flex to follow the guidewire, and the tapered end of the dilator and the distally-directed inclined surface of the ridge act to dilate the flesh about the opening to facilitate passage of the sheath. The introducer and valve may be used alone, or respectively with valves or introducers of other design. A base for attachment of the introducer to the patient is also described.

    摘要翻译： 医疗导管导引器和止血阀组件包括具有限定导管的细长管的护套，设置在护套的近端处并进一步限定导管和孔的壳体，以及尺寸适于插入穿过毂的柔性细长扩张器 和鞘导管。 扩张器具有锥形的远端尖端并且限定轴向导管和具有远侧和近侧定向的倾斜表面的环形脊。 当与扩张器组装时，护套的远端紧邻脊的向近侧倾斜的表面。 用于密封导管的止血阀设置成与管道对准，并且在密封接合时限定了用于使膨胀器和脊通过的孔，用于密封接合，并且当扩张器被移除时密封。 阀具有限定第一直径的孔的壳体和大于第一直径的第二直径的阀元件。 阀设置在孔内并且受到外部施加的径向力的作用，使得阀呈现穹顶形状，其中凸表面抵抗体内流体的压力设置。 当导引器组件被引入到穿过穿刺孔延伸到血管中的导丝上的主体中时，扩张器和皮肤弯曲以跟随导丝，并且扩张器的锥形端和脊的远侧倾斜的表面作用到 扩大围绕开口的肉体，以方便鞘的通过。 导引器和阀可以单独使用，也可以分别用于其他设计的阀门或导引器。 还描述了用于将导引器附接到患者的基部。

    Device and method for fluoroscope-monitored percutaneous puncture treatment
    39.
    发明授权
    Device and method for fluoroscope-monitored percutaneous puncture treatment 失效
    荧光透视监测经皮穿刺治疗的装置和方法

    公开(公告)号：US4485815A

    公开(公告)日：1984-12-04

    申请号：US412594

    申请日：1982-08-30

    申请人： Kurt Amplatz ,  Frank Kotula

    发明人： Kurt Amplatz ,  Frank Kotula

    IPC分类号： A61B17/34 ,  A61B19/00

    CPC分类号： A61B17/3403 ,  A61B2017/00902 ,  A61B90/39

    摘要： A device for performing percutaneous puncture treatment of a patient includes an elongate radiolucent plastic handle with a central portion and two opposite elongated end portions. A hollow radiopaque needle has a hub at its proximal end which is releasably mounted in the central portion of the handle so that the needle is perpendicular to an axis through the end portions. The distal end of the needle has a puncturing tip. An internal fluid passage in the needle is open to the tip and the hub so that fluid may be drained from a patient's body through the passage when the needle is inserted in the patient's body. The needle and central portion of the handle are aligned under a field of view of a fluoroscope. The handle is held by the grips which are outside of the field of view of the fluoroscope. While the doctor continuously monitors progress of the needle on the fluoroscope, the puncturing tip is inserted through the skin and moved to an internal location for aspiration of fluid. Medical personnel are safely outside of the field of view of the fluoroscope during the entire process.

    摘要翻译： 用于对患者进行经皮穿刺治疗的装置包括具有中心部分和两个相对的细长端部的细长的射线可透过塑料手柄。 中空的不透射线针在其近端具有轮毂，其可释放地安装在手柄的中心部分中，使得针通过端部垂直于轴线。 针的远端具有穿刺尖端。 针中的内部流体通道对尖端和轮毂开放，使得当针插入患者体内时，流体可以从患者的身体通过通道排出。 手柄的针头和中心部分在荧光镜的视野下对齐。 手柄由位于荧光镜视野外的把手握持。 当医生连续监测荧光镜上针的进展时，穿刺尖端插入穿过皮肤并移动到内部位置以抽吸流体。 在整个过程中，医务人员安全地离开荧光镜的视野。