-
公开(公告)号：US20220056184A1
公开(公告)日：2022-02-24
申请号：US17460058
申请日：2021-08-27
Applicant: Life Technologies AS
Inventor： Geir Fonnum , Nils Pontus Lundberg , Muhammed Talha Gokmen , Synne Larsen , Wilhelm Glomm , Heidi Johnsen , Ruth Schmid , Lars Kilaas
IPC: C08F265/10 , C08F120/54 , C08F265/06
Abstract: This invention relates to monodisperse cross-linked hydrogel polymer particles comprising a polymer formed from (a) a hydrophilic vinylic monomer; and (b) a crosslinker comprising at least two vinyl groups. The invention also relates to monodisperse seed particles with a Z-average diameter of from 100 nm to 1500 nm that comprise a plurality of non-crosslinked oligomers of poly N,N-dimethylacrylamide. Also provided are methods of forming the monodisperse cross-linked hydrogel polymer particles and monodisperse seed particles.
-
公开(公告)号：US11041068B2
公开(公告)日：2021-06-22
申请号：US16305372
申请日：2017-06-07
Inventor： Kristian Andersson , Geir Fonnum , Korbinian Heil
IPC: C08L25/14 , C08L25/08 , B01J19/00 , C08F212/08 , C08F220/58 , C08F293/00
Abstract: This invention relates to polymer particles for solid phase oligonucleotide synthesis. The oligonucleotide may be linked to the particle via a linker having an amide-oligoethyleneglycol-amine structure. The particles may be considered to act as a solid support during the oligonucleotide synthesis. Also disclosed are processes for preparing such polymer particles, compositions and systems comprising such particles, and uses thereof.
-
公开(公告)号：US20200308630A1
公开(公告)日：2020-10-01
申请号：US16849833
申请日：2020-04-15
Applicant: LIFE TECHNOLOGIES AS
Inventor： Darren Ellis , Geir Fonnum , Nini Kjus
IPC: C12Q1/6806 , C12N15/10
Abstract: A method for processing a nucleic acid, in which the nucleic acid is exposed to an aqueous medium which includes a polyol in sufficient proportion for at least a portion of the nucleic acid to enter or remain in an extra-solution phase. Thus, a polyol may be used to bind a nucleic acid which is in solution to a solid support or to wash a nucleic acid on a solid support whilst maintaining it on the support. The polyol may for example be a C2-C10 alkanediol.
-
公开(公告)号：US09309368B2
公开(公告)日：2016-04-12
申请号：US14152793
申请日：2014-01-10
Applicant: LIFE TECHNOLOGIES AS
Inventor： Arne Jørgedal , Elin Marie Aksnes , Geir Fonnum , Astrid Molteberg , Rolf Nordal , Henning Pettersen , Tollef Tårneby , Solveig Staale , Ellen Weng , Finn Hansen , Silje Nordbø , Oddvar Aune , Arvid Berge , John Bjørgum , Turid Ellingsen , John Ugelstad
IPC: C08J9/16 , C08F257/02 , C08F265/04 , C08F265/10 , C08F291/00 , C08J9/224
CPC classification number: C08J9/16 , C08F2/22 , C08F257/02 , C08F265/04 , C08F265/10 , C08F291/00 , C08J9/22 , C08J9/224 , C08J2203/14 , C08J2325/06 , C08J2347/00
Abstract: A process for the preparation of monodisperse polymer particles which are formed by contacting monomers with aqueous dispersions comprising monodisperse swellable seed polymers/oligomers, and initiating polymerization in the presence of a steric stabilizer. The resulting swollen seed particles are characterized by the particle mode diameter.
Abstract translation: 通过使单体与包含单分散可溶胀种子聚合物/低聚物的水性分散体接触而形成的单分散聚合物颗粒的制备方法，以及在空间稳定剂存在下引发聚合。 所得的溶胀种子颗粒的特征在于颗粒模式直径。
-
公开(公告)号：US08658733B2
公开(公告)日：2014-02-25
申请号：US13649045
申请日：2012-10-10
Applicant: Life Technologies AS , Arvid Tygve Berge , Viola Ugelstad
Inventor： Arne Jorgedal , Elin Aksnes , Geir Fonnum , Astrid Molteberg , Rolf Nordal , Henning Pettersen , Tollef Taarneby , Solveig Staale , Ellen Weng , Finn Hansen , Silje Nordbo , Oddvar Aune , Arvid Berge , John Bjorgum , Turid Ellingsen , John Ugelstad
IPC: C08F8/30
CPC classification number: C08J9/16 , C08F2/22 , C08F257/02 , C08F265/04 , C08F265/10 , C08F291/00 , C08J9/22 , C08J9/224 , C08J2203/14 , C08J2325/06 , C08J2347/00
Abstract: A process for the preparation of monodisperse polymer particles which are formed by contacting monomers with aqueous dispersions comprising monodisperse swellable seed polymers/oligomers, and initiating polymerization in the presence of a steric stabilizer. The resulting swollen seed particles are characterized by the particle mode diameter.
Abstract translation: 通过使单体与包含单分散可溶胀种子聚合物/低聚物的水性分散体接触而形成的单分散聚合物颗粒的制备方法，以及在空间稳定剂存在下引发聚合。 所得的溶胀种子颗粒的特征在于颗粒模式直径。
-
Patent Agency Ranking
公开(公告)号：US11261480B2
公开(公告)日：2022-03-01
申请号：US16849833
申请日：2020-04-15
Applicant: LIFE TECHNOLOGIES AS
Inventor： Darren Ellis , Geir Fonnum , Nini Kjus
IPC: C12Q1/68 , C12N15/10 , C12Q1/6806
Abstract: A method for processing a nucleic acid, in which the nucleic acid is exposed to an aqueous medium which includes a polyol in sufficient proportion for at least a portion of the nucleic acid to enter or remain in an extra-solution phase. Thus, a polyol may be used to bind a nucleic acid which is in solution to a solid support or to wash a nucleic acid on a solid support whilst maintaining it on the support. The polyol may for example be a C2-C10 alkanediol.
-
公开(公告)号：US09909165B2
公开(公告)日：2018-03-06
申请号：US15431678
申请日：2017-02-13
Applicant: LIFE TECHNOLOGIES AS
Inventor： Darren Ellis , Geir Fonnum , Nini Kjus
CPC classification number: C12Q1/6806 , C12N15/1006 , C12N15/1013
Abstract: A method for processing a nucleic acid, in which the nucleic acid is exposed to an aqueous medium which includes a polyol in sufficient proportion for at least a portion of the nucleic acid to enter or remain in an extra-solution phase. Thus, a polyol may be used to bind a nucleic acid which is in solution to a solid support or to wash a nucleic acid on a solid support while maintaining it on the support. The polyol may for example be a C2-C10 alkanediol.
-
公开(公告)号：US09187691B2
公开(公告)日：2015-11-17
申请号：US14190054
申请日：2014-02-25
Applicant: LIFE TECHNOLOGIES AS
Inventor： Ellen Weng , Geir Fonnum , Grete Modahl , Astrid Molteberg , Torkel Stene
IPC: G01N33/553 , G01N33/544 , C09K11/06 , B82Y25/00 , B82Y40/00 , G01N33/543 , H01F1/01 , H01F41/00 , C09K11/02 , H01F1/00 , H01F1/26 , C08F220/18
CPC classification number: C09K11/06 , B82Y25/00 , B82Y40/00 , C08F220/18 , C09K11/025 , G01N33/5434 , H01F1/0018 , H01F1/01 , H01F1/26 , H01F41/00 , Y10T428/2991 , Y10T428/2998
Abstract: A coated magnetic particle comprising an optionally porous magnetic polymer particle of a matrix polymer, said polymer particle having on a surface and/or in the pores thereof superparamagnetic crystals, said coated particle having a coat formed of a coating polymer, wherein said coated magnetic particle is essentially non-autofluorescent.
Abstract translation: 一种涂覆的磁性颗粒，其包含基质聚合物的任选多孔磁性聚合物颗粒，所述聚合物颗粒在表面上和/或其孔中具有超顺磁性晶体，所述涂覆颗粒具有由涂覆聚合物形成的涂层，其中所述涂覆的磁性颗粒 本质上是非自发荧光。
-
公开(公告)号：US08697453B2
公开(公告)日：2014-04-15
申请号：US13651120
申请日：2012-10-12
Applicant: Life Technologies Corporation
Inventor： Ellen Weng , Geir Fonnum , Grete Modahl , Astrid Molteberg , Erling Finne
IPC: G01N33/553 , G01N33/544 , B32B5/16 , A61K49/10
CPC classification number: C09K11/06 , B82Y25/00 , B82Y40/00 , C08F220/18 , C09K11/025 , G01N33/5434 , H01F1/0018 , H01F1/01 , H01F1/26 , H01F41/00 , Y10T428/2991 , Y10T428/2998
Abstract: A coated magnetic particle comprising an optionally porous magnetic polymer particle of a matrix polymer, said polymer particle having on a surface and/or in the pores thereof superparamagnetic crystals, said coated particle having a coat formed of a coating polymer, wherein said coated magnetic particle is essentially non-autofluorescent.
Abstract translation: 一种涂覆的磁性颗粒，其包含基质聚合物的任选多孔磁性聚合物颗粒，所述聚合物颗粒在表面上和/或其孔中具有超顺磁性晶体，所述涂覆颗粒具有由涂覆聚合物形成的涂层，其中所述涂覆的磁性颗粒 本质上是非自发荧光。
-
公开(公告)号：US20130099151A1
公开(公告)日：2013-04-25
申请号：US13651120
申请日：2012-10-12
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Ellen WENG , Geir Fonnum , Grete Modahl , Astrid Molteberg , Erling Finne
CPC classification number: C09K11/06 , B82Y25/00 , B82Y40/00 , C08F220/18 , C09K11/025 , G01N33/5434 , H01F1/0018 , H01F1/01 , H01F1/26 , H01F41/00 , Y10T428/2991 , Y10T428/2998
Abstract: A coated magnetic particle comprising an optionally porous magnetic polymer particle of a matrix polymer, said polymer particle having on a surface and/or in the pores thereof superparamagnetic crystals, said coated particle having a coat formed of a coating polymer, wherein said coated magnetic particle is essentially non-autofluorescent.
Abstract translation: 一种涂覆的磁性颗粒，其包含基质聚合物的任选多孔磁性聚合物颗粒，所述聚合物颗粒在表面上和/或其孔中具有超顺磁性晶体，所述涂覆颗粒具有由涂覆聚合物形成的涂层，其中所述涂覆的磁性颗粒 本质上是非自发荧光。
-
-
-
-
-
-
-
-
-
Search Results
42
records
(took 0.049 seconds)
