公开(公告)号：US20210170159A1

公开(公告)日：2021-06-10

申请号：US17173944

申请日：2021-02-11

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/829 ,  A61M60/896 ,  A61M60/818 ,  A61M60/419 ,  A61M60/857 ,  A61M60/422

Abstract: Apparatus and methods are described including a blood pump configured to be placed inside a body of subject. The blood pump includes an impeller, a frame disposed around the impeller, and a distal-tip portion disposed distally with respect to the frame. A duckbill valve is disposed entirely within a distal most 10 mm of the distal-tip portion. The duckbill valve defines a wide inlet and a narrow tip that defines a slit therethrough. The duckbill valve is proximally facing, such that the wide inlet faces a distal end of the distal-tip portion and such that the narrow tip faces away from the distal end of distal-tip portion. Other applications are also described.

公开(公告)号：US20200237985A1

公开(公告)日：2020-07-30

申请号：US16810172

申请日：2020-03-05

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M1/12 ,  A61M1/10

Abstract: Apparatus and methods are described including manufacturing a housing for an impeller of a blood pump by placing an inner lining around a mandrel, placing a cylindrical portion of a frame around the inner lining, and placing a distal portion of an elongate tube around a portion of the frame. While the distal portion of the elongate tube is disposed around the portion of the frame, the inner lining, the frame, and the distal portion of the elongate tube are heated, via the mandrel, and pressure is applied from outside the distal portion of the elongate tube, such as to cause the distal portion of the elongate tube to conform with a structure of the struts of the frame, and to cause the inner lining and the distal portion of the elongate tube to become coupled to the frame. Other applications are also described.

公开(公告)号：US20250144399A1

公开(公告)日：2025-05-08

申请号：US19013744

申请日：2025-01-08

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Jacob Leisner Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/122 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/205 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/804 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54

Abstract: Apparatus and methods are described including a left-ventricular assist device. A pump pumps blood from the subject's left ventricle to the subject's aorta, via a tube. A distal-tip element is disposed distally to the pump and defines a straight proximal portion that defines a longitudinal axis, and a curved distal portion that is shaped such as to curve in a first direction with respect to the longitudinal axis of the straight proximal portion before passing through an inflection point and curving in a second direction with respect to the longitudinal axis of the straight proximal portion, such that the curved distal portion defines a bulge on one side of the longitudinal axis of the straight proximal portion. Other applications are also described.

公开(公告)号：US20250144398A1

公开(公告)日：2025-05-08

申请号：US19013727

申请日：2025-01-08

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Jacob Leisner Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/122 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/205 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/804 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54

Abstract: Apparatus and methods are described including a left-ventricular assist device configured to assist left-ventricular functioning of a subject. The left-ventricular assist device includes a frame, a rigid axial shaft extending from a proximal end of the frame to a distal end of the frame, and an impeller disposed on the rigid axial shaft. A motor is disposed outside the subject's body, and a flexible drive cable extends from outside the subject's body to the axial shaft. The drive cable imparts rotational motion from the motor to the rigid axial shaft, to thereby rotate the impeller. Other applications are also described.

公开(公告)号：US20250082920A1

公开(公告)日：2025-03-13

申请号：US18955121

申请日：2024-11-21

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Jacob Leisner Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/122 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/205 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/804 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54

Abstract: Apparatus and methods are described including a blood pump that includes an impeller configured to pump blood through a subject's body, and a frame disposed around the impeller. In a radially-non-constrained configuration of the frame, the frame defines a proximal conical portion and a cylindrical portion disposed distally to the proximal conical portion. The blood pump is configured such that such that, during at least some of the operation of the blood pump, at least a portion of the impeller is disposed within the proximal conical portion of the frame. Other applications are also described.

公开(公告)号：US20240277996A1

公开(公告)日：2024-08-22

申请号：US18652956

申请日：2024-05-02

Applicant: Magenta Medical Ltd

Inventor： Yosi Tuval ,  Gad Lubinsky ,  Victor Troshin ,  Hagit Zemer Harel ,  Ori Friedland ,  Daniel Rosenblum ,  Avi Rozenfeld

IPC: A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

CPC classification number: A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

Abstract: Apparatus and methods are described including a ventricular assist device that includes an axial shaft and an impeller disposed on the axial shaft, the impeller being configured to pump blood. A frame is disposed around the impeller. A distal thrust bearing is disposed within the frame, the distal end of the axial shaft being configured to engage with the distal thrust bearing such as to prevent the axial shaft from undergoing axial motion in response to variations in the pressure gradient against which the impeller pumps blood. A plurality of connecting struts extend radially inwardly from the frame to the distal thrust bearing and couple the thrust bearing to the frame. The frame and the connecting struts are formed as a single integral body. Other applications are also described.

公开(公告)号：US20240277995A1

公开(公告)日：2024-08-22

申请号：US18652930

申请日：2024-05-02

Applicant: Magenta Medical Ltd

Inventor： Yosi Tuval ,  Gad Lubinsky ,  Victor Troshin ,  Hagit Zemer Harel ,  Ori Friedland ,  Daniel Rosenblum ,  Avi Rozenfeld

IPC: A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

CPC classification number: A61M60/808 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/414 ,  A61M60/81 ,  A61M60/825

Abstract: Apparatus and methods are described including packaging for a ventricular assist device. The packaging defines a pump-head chamber in which the pump head is packaged in a non-radially constrained configuration. A catheter-securement piece is shaped to define a hole and is configured to secure a distal end of the delivery catheter to the packaging by securing the delivery catheter within the hole. The packaging is configured such that the pump head is configured to be radially constrained by being retracted into the distal end of the delivery catheter, while the delivery catheter is secured within the hole. Other applications are also described.

公开(公告)号：US12023476B2

公开(公告)日：2024-07-02

申请号：US17173944

申请日：2021-02-11

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804

CPC classification number: A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/382 ,  F04D29/526 ,  F04D29/545 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804 ,  A61M2205/0216 ,  A61M2205/3344 ,  A61M2230/30

Abstract: Apparatus and methods are described including a blood pump configured to be placed inside a body of subject. The blood pump includes an impeller, a frame disposed around the impeller, and a distal-tip portion disposed distally with respect to the frame. A duckbill valve is disposed entirely within a distal most 10 mm of the distal-tip portion. The duckbill valve defines a wide inlet and a narrow tip that defines a slit therethrough. The duckbill valve is proximally facing, such that the wide inlet faces a distal end of the distal-tip portion and such that the narrow tip faces away from the distal end of distal-tip portion. Other applications are also described.

公开(公告)号：US11944800B2

公开(公告)日：2024-04-02

申请号：US17177296

申请日：2021-02-17

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/38 ,  F04D29/52 ,  F04D29/54 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804

CPC classification number: A61M60/148 ,  A61M60/126 ,  A61M60/13 ,  A61M60/135 ,  A61M60/216 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/894 ,  A61M60/896 ,  B05D1/02 ,  F04D29/382 ,  F04D29/526 ,  F04D29/545 ,  A61M60/122 ,  A61M60/205 ,  A61M60/804 ,  A61M2205/0216 ,  A61M2205/3344 ,  A61M2230/30

Abstract: Apparatus and methods are described including a blood pump configured to be placed inside a body of subject, the blood pump including an impeller configured to pump the subject's blood by rotating, and an axial shaft upon which the impeller is disposed. Proximal and distal radial bearings are configured to stabilize the axial shaft radially during rotation of the impeller. An atraumatic distal-tip portion is disposed distally with respect to the impeller, the atraumatic distal-tip portion including an inflatable portion. A purging fluid is pumped toward the distal-tip portion, such as to (a) purge the distal bearing, and (b) inflate the inflatable portion of the distal-tip portion. Other applications are also described.

公开(公告)号：US20230218887A1

公开(公告)日：2023-07-13

申请号：US18122486

申请日：2023-03-16

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Gad Lubinsky ,  Hagit Zemer Harel ,  Ori Friedland ,  Daniel Rosenblum ,  Avi Rozenfeld

IPC: A61M60/414 ,  A61M60/237

CPC classification number: A61M60/414 ,  A61M60/237 ,  A61M60/13

Abstract: Apparatus and methods are described for manufacturing a housing for an impeller of a blood pump. A mandrel is placed inside an inner lining, with a central cylindrical portion of a frame disposed around the inner lining, the mandrel being shorter than a length of the inner lining. A portion of an elongate tube is placed around at least a portion of the frame. The inner lining, the frame and the portion of the elongate tube are heated, via the mandrel, and, while heating the inner lining, the frame, and the portion of the elongate tube, pressure is applied from outside the portion of the elongate tube, such as to cause the portion of the elongate tube to become coupled to the frame. Other applications are also described.