公开(公告)号：US20160068857A1

公开(公告)日：2016-03-10

申请号：US14945061

申请日：2015-11-18

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： David J. Bowen ,  Catherine Chay ,  Artem Evdokimov ,  Megan N. Schroder ,  Rachael N. Slightom ,  Uma R. Kesanapalli ,  Nengbing Tao ,  Andrew M. Wollacott

IPC: C12N15/82 ,  C07K14/32

CPC classification number: C12N15/8286 ,  C07K14/001 ,  C07K14/32 ,  Y02A40/162

Abstract: The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.

公开(公告)号：US11987800B2

公开(公告)日：2024-05-21

申请号：US17934287

申请日：2022-09-22

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Catherine A. Chay ,  Todd A. Ciche ,  Stanislaw Flasinski ,  Arlene R. Howe

IPC: C12N15/82 ,  A01N63/50 ,  C07K14/24 ,  C07K14/325

CPC classification number: C12N15/8286 ,  A01N63/50 ,  C07K14/24 ,  C07K14/325

Abstract: A pesticidal protein class of PirA, PirB, and PirAB fusion proteins exhibiting toxic activity against Coleopteran, Lepidopteran, and Hemipteran pest species is disclosed. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the PirA, PirB, and PirAB fusion proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran, Lepidopteran, and Hemipteran infestation are provided which contain recombinant nucleic acid sequences encoding the PirA, PirB, and PirAB fusion proteins. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran, Lepidopteran, and Hemipteran species pests using the PirA, PirB, and PirAB fusion proteins are also provided.

公开(公告)号：US11905520B2

公开(公告)日：2024-02-20

申请号：US18052819

申请日：2022-11-04

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Catherine A. Chay ,  Todd A. Ciche ,  Uma R. Kesanapalli ,  Jennifer L. Lutke

IPC: C12N15/82 ,  C12Q1/6895 ,  A01N37/46 ,  A01N63/50 ,  G01N33/53

CPC classification number: C12N15/8286 ,  A01N37/46 ,  A01N63/50 ,  C12Q1/6895 ,  C12Q2600/13 ,  G01N33/5308 ,  Y02A40/146 ,  A01N63/50 ,  A01N63/25

Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL pesticidal proteins are also provided.

公开(公告)号：US11825850B2

公开(公告)日：2023-11-28

申请号：US17556428

申请日：2021-12-20

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Catherine A. Chay ,  Arlene R. Howe ,  Matthew S. Marengo ,  Jason Meyer ,  Jason S Milligan ,  Brian E. Weiner

IPC: A01N63/50 ,  C07K14/32 ,  C12N15/82 ,  C12Q1/68 ,  C07K14/325 ,  C12Q1/6895

CPC classification number: A01N63/50 ,  C07K14/325 ,  C12N15/8286 ,  C12Q1/6895

Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC4029, TIC4029_1, and TIC4029_8. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding pesticidal proteins of the TIC4029 class. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the TIC4029 class in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC4029, TIC4029_1, and TIC4029_8 pesticidal proteins are also provided.

公开(公告)号：US11702455B2

公开(公告)日：2023-07-18

申请号：US16894459

申请日：2020-06-05

Applicant: Monsanto Technology LLC

Inventor： James A. Baum ,  David J. Bowen ,  Catherine A. Chay ,  David J. Chi ,  William P. Clinton ,  Crystal L. Dart ,  Leigh English ,  Stanislaw Flasinski ,  Victor M. Guzov ,  Kevin A. Jarrell ,  Uma R. Kesanapalli ,  Thomas M. Malvar ,  Robert M. McCarroll ,  Jason S. Milligan ,  Jay P. Morgenstern ,  Deborah G. Rucker ,  Sara A. Salvador ,  Temple F. Smith ,  Carlos E. Soto ,  Collin M. Stultz ,  Brian M. Turczyk ,  Ty T. Vaughn ,  Moritz W. F. Von Rechenberg

IPC: C07K14/325 ,  C12N15/82 ,  A01N63/50

CPC classification number: C07K14/325 ,  A01N63/50 ,  C12N15/8286 ,  Y02A40/146 ,  A01N63/50 ,  A01N63/23 ,  A01N63/50 ,  A01N63/50

Abstract: Disclosed herein are nucleotide sequences encoding an insecticidal protein exhibiting Lepidopteran inhibitory activity, as well as novel insecticidal proteins referred to herein as a BCW 001, BCW 002, BCW 003, and BCW toxic protein-containing chimeras and BCW toxin insecticide, transgenic plants expressing the chimeras or the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.

公开(公告)号：US20220220160A1

公开(公告)日：2022-07-14

申请号：US17561332

申请日：2021-12-23

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Todd A. Ciche ,  Arlene R. Howe ,  Stephanie C. Waldheuser ,  Kimberly M. Wegener

IPC: C07K14/325 ,  A01N63/50 ,  A01P7/04 ,  C12N15/82

Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC13085 and TIC13087. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC13085 and TIC13087 pesticidal proteins are also provided.

公开(公告)号：US11312752B2

公开(公告)日：2022-04-26

申请号：US16810810

申请日：2020-03-05

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Catherine A. Chay ,  Arlene R. Howe ,  Uma Kesanapalli

IPC: C07K14/32 ,  C12N15/82 ,  C07K14/325 ,  C12Q1/6895

Abstract: Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC4472, TIC4472PL, TIC1425, TIC2613, and TIC2613PL. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC4472, TIC4472PL, TIC1425, TIC2613, and TIC2613PL pesticidal proteins are also provided.

公开(公告)号：US11225672B2

公开(公告)日：2022-01-18

申请号：US16658892

申请日：2019-10-21

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： David J. Bowen ,  Catherine A. Chay ,  Todd A. Ciche ,  Stanislaw Flasinski ,  Arlene R. Howe ,  Krishnakumar Sridharan

IPC: C12N15/82 ,  C07K14/195 ,  A01N37/46 ,  C07K14/32 ,  A01N63/50

Abstract: A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins are also provided.

公开(公告)号：US11193138B2

公开(公告)日：2021-12-07

申请号：US16684029

申请日：2019-11-14

Applicant: Monsanto Technology LLC

Inventor： Gregory J. Bean ,  David J. Bowen ,  Catherine A. Chay ,  Arlene R. Howe ,  Jason S. Milligan ,  Yong Yin

IPC: C07K14/195 ,  C12N15/82 ,  A01N63/20

Abstract: Insecticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC3668, TIC3669, TIC3670, TIC4076, TIC4078, TIC4260, TIC4346, TIC4826, TIC4861, TIC4862, TIC4863, and TIC-3668-type proteins. DNA molecules and constructs are provided which contain a polynucleotide sequence encoding one or more of the disclosed TIC3668-type proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Coleopteran infestation are provided which contain polynucleotide sequences encoding the insecticidal proteins of the present invention. Methods for detecting the presence of the polynucleotides or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using any of the TIC3668-type insecticidal proteins are also provided.

公开(公告)号：US20190249190A1

公开(公告)日：2019-08-15

申请号：US16391748

申请日：2019-04-23

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Catherine Chay ,  Artem Evdokimov ,  Stanislaw Flasinski ,  Uma R. Kesanapalli ,  Megan N. Schroder ,  Rachael N. Slightom ,  Nengbing Tao ,  Andrew M. Wollacott

IPC: C12N15/82 ,  C07K14/32

Abstract: The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.