公开(公告)号：US20070136132A1

公开(公告)日：2007-06-14

申请号：US11605207

申请日：2006-11-28

申请人： Douglas Weiser ,  Mark Wood ,  Kevin Preston

发明人： Douglas Weiser ,  Mark Wood ,  Kevin Preston

IPC分类号： G06Q30/00

CPC分类号： G06Q30/0267 ,  G06Q30/02 ,  G06Q30/0261 ,  G06Q50/265 ,  H04L12/14 ,  H04L12/1432 ,  H04W4/023 ,  H04W4/06 ,  H04W88/02

摘要： A system and method for distributing promotions to mobile devices located in a broadcast target area and as a function of a promotion client identifier, the system and method including transmitting a first plurality of promotions associated with a plurality of promotion clients having locations in a target area, receiving a promotion client identifier, receiving the transmitted promotions, and displaying one of the received promotions on a mobile device as a function of the promotion identifier.

摘要翻译： 一种用于将促销分发到位于广播目标区域中的移动设备并根据促销客户端标识符的功能的系统和方法，所述系统和方法包括：传送与多个促销客户端相关联的第一多个促销活动，所述促销客户端具有目标区域中的位置 接收促销客户标识符，接收所传送的促销，以及根据促销标识符在移动设备上显示接收到的促销活动之一。

公开(公告)号：US20070124368A1

公开(公告)日：2007-05-31

申请号：US11602461

申请日：2006-11-20

申请人： Douglas Weiser ,  Mark Wood ,  Kevin Preston

发明人： Douglas Weiser ,  Mark Wood ,  Kevin Preston

IPC分类号： G06F15/16 ,  H04B7/00

CPC分类号： G06Q30/04 ,  G08B25/006 ,  G08B27/00 ,  H04L12/18

摘要： A system and method of admission control for authorizing a submission of a broadcast message to a broadcast target area includes receiving a broadcast message record including the broadcast message and the broadcast target area for the broadcast message and validating the authority of a broadcast message originator originating the broadcast message record as a function of a broadcast message originator parameter. The method also includes identifying a broadcast transmission network providing broadcast message transmission to broadcast message receiving devices located within the broadcast target area and validating the broadcast transmission network against a broadcast transmission network parameter. The method further includes forwarding the broadcast message record to an output interface associated with the broadcast transmission network for transmission to the broadcast message receiving devices within the broadcast target area.

摘要翻译： 授权向广播目标区域提交广播消息的接纳控制的系统和方法包括：接收包括广播消息的广播消息记录和用于广播消息的广播目标区域，并且验证发起广播消息的广播消息发起者的权限 作为广播消息始发者参数的函数的广播消息记录。 该方法还包括识别广播传输网络，其向广播目标区域内的广播消息接收设备提供广播消息传输，并根据广播传输网络参数验证广播传输网络。 该方法还包括将广播消息记录转发到与广播传输网络相关联的输出接口，以便传输到广播目标区域内的广播消息接收设备。

公开(公告)号：US20060065309A1

公开(公告)日：2006-03-30

申请号：US11238101

申请日：2005-09-28

申请人： Jeremy Leasure ,  Timothy Smith ,  John Hardin ,  Mark Wood

发明人： Jeremy Leasure ,  Timothy Smith ,  John Hardin ,  Mark Wood

IPC分类号： B67D5/00

CPC分类号： F04B41/02 ,  Y10T137/86051

摘要： An air compressor assembly includes an air compressor mounted to a compressed air storage tank via a mounting assembly. The mounting assembly allows removal of the air compressor from the compressed air storage tank so that the air compressor and the compressed air storage tank may be utilized independently of the other.

摘要翻译： 空气压缩机组件包括通过安装组件安装到压缩空气存储箱的空气压缩机。 安装组件允许空气压缩机从压缩空气存储箱中移除，使得空气压缩机和压缩空气储罐可以独立于另一个使用。

公开(公告)号：US20050279317A1

公开(公告)日：2005-12-22

申请号：US11154020

申请日：2005-06-16

申请人： Jeremy Leasure ,  Mark Wood ,  Gary Kreutzer ,  John Hardin

发明人： Jeremy Leasure ,  Mark Wood ,  Gary Kreutzer ,  John Hardin

IPC分类号： F01M1/00 ,  F01M1/16 ,  F01M11/12 ,  F02F7/00

CPC分类号： F01M11/0408 ,  F01M1/16 ,  F01M11/12 ,  F01M2011/0416

摘要： A mechanical device including a crankcase and reservoir plug suitable for detecting the quantity of lubricant is disclose. In an aspect, the reservoir plug is configured to permit observation of the interior of the plug/crankcase in order to observe the level of contained lubricant. The drain hole for receiving the plug is disposed to encompass the range between the maximum acceptable lubricant level and the minimum acceptable lubricant level. The plug may include a main body portion and transparent portion for permitting observation of fluid, disposed on a second side, from a first side of a sealing interface.

摘要翻译： 公开了一种包括适于检测润滑剂量的曲轴箱和储存器塞的机械装置。 在一方面，储存器塞被构造成允许观察塞/曲轴箱的内部，以便观察所容纳的润滑剂的水平。 用于接收塞子的排水孔设置成包含最大可接受润滑剂水平和最小可接受润滑剂水平之间的范围。 塞子可以包括主体部分和透明部分，用于允许从密封界面的第一侧观察设置在第二侧上的流体。

公开(公告)号：US06467394B1

公开(公告)日：2002-10-22

申请号：US09639573

申请日：2000-08-14

申请人： Mark Wood ,  Shane Dexter ,  Allen Palmer

发明人： Mark Wood ,  Shane Dexter ,  Allen Palmer

IPC分类号： F01B700

CPC分类号： F04B1/0413 ,  F04B1/0426

摘要： An oilless high pressure pump suitable for use in devices such as pressure washers and the like is described. The pump includes an eccentric assembly suitable for converting rotary motion of a rotating shaft to rectilinear motion. One or more straps couple the eccentric assembly to the pump's piston assembly. The straps communicate the rectilinear motion of the eccentric assembly to the piston assembly for reciprocating the pump's pistons to pump the liquid.

摘要翻译： 描述适用于诸如压力清洗机等的装置的无油高压泵。 泵包括适于将旋转轴的旋转运动转换为直线运动的偏心组件。 一个或多个带将偏心组件耦合到泵的活塞组件。 带子将偏心组件的直线运动传递到活塞组件，以使泵的活塞往复运动以泵送液体。

公开(公告)号：US09743933B2

公开(公告)日：2017-08-29

申请号：US13231524

申请日：2011-09-13

申请人： Molly Phillips-Hungerford ,  Mark Wood ,  Shawn Ryan ,  Benjamin E. Morris

发明人： Molly Phillips-Hungerford ,  Mark Wood ,  Shawn Ryan ,  Benjamin E. Morris

IPC分类号： A61B17/10 ,  A61B17/128 ,  A61B17/122 ,  A61B90/00

CPC分类号： A61B17/1285 ,  A61B17/122 ,  A61B17/1227 ,  A61B17/128 ,  A61B90/03

摘要： Release mechanism for medical device includes a bushing having a proximal end, a distal end and a channel extending therethrough. Plurality of extend proximally from the distal end are biased toward a release configuration in which engagement surfaces at distal ends thereof retract radially into the channel. A core pin insertable through the channel applies a radially expansive pressure to move the arms radially outward to a locking configuration. Engagement surfaces of the first and second arms connect to a retaining surface of a tissue treatment device containing capsule, which extends at an angle relative to the engagement surfaces selected so that a first portion of a force transmitted along an axis of the bushing moves the arms radially inward toward the release configuration before a second portion of the force exceeds a threshold level associated with the removal of a tissue treatment device from gripped tissue.

公开(公告)号：US09387104B2

公开(公告)日：2016-07-12

申请号：US13335615

申请日：2011-12-22

申请人： Ra Nam ,  Mark Wood ,  John Pereira ,  Eric M. Schneider ,  William C. Bertolino ,  Naroun Suon

发明人： Ra Nam ,  Mark Wood ,  John Pereira ,  Eric M. Schneider ,  William C. Bertolino ,  Naroun Suon

IPC分类号： A61F2/06 ,  A61F2/962 ,  A61F2/95

CPC分类号： A61F2/962 ,  A61F2002/9522

摘要： A loading basket is secured at its proximal end to a portion of a delivery device. The stent engages with the interior of the stent basket when loaded onto the delivery device to prevent shifting or movement of the stent during delivery of the stent to a desired location within the bodily lumen. In at least one embodiment, the loading basket has a proximal end, a distal end, and a braided surface. The loading basket comprises a proximal end portion, a proximal transition portion, a body portion, a distal transition portion, a distal end portion, and an angled inward distal end. When loaded onto the delivery device, the outer surface of the stent contacts at least the angled inward distal end of the delivery device and movement of the stent is prevented.

摘要翻译： 装载篮在其近端固定到输送装置的一部分。 支架在装载到输送装置上时与支架的内部接合，以防止在将支架输送到体腔内的期望位置时支架的移动或移动。 在至少一个实施例中，装载篮具有近端，远端和编织表面。 装载篮包括近端部分，近端过渡部分，主体部分，远侧过渡部分，远端部分和倾斜的内侧远端。 当装载到输送装置上时，支架的外表面至少与输送装置的倾斜的内向远端相接触，并防止了支架的移动。

公开(公告)号：US09155643B2

公开(公告)日：2015-10-13

申请号：US13092762

申请日：2011-04-22

申请人： Claude Clerc ,  Alexander Turovsky ,  Michael E. Zupkofska ,  Christopher Dubois ,  Mark Wood ,  Gary Jordan

发明人： Claude Clerc ,  Alexander Turovsky ,  Michael E. Zupkofska ,  Christopher Dubois ,  Mark Wood ,  Gary Jordan

IPC分类号： A61F2/90 ,  D04C1/06 ,  D04C3/48 ,  D04C7/00

CPC分类号： A61F2/90 ,  A61F2230/0078 ,  A61F2240/001 ,  A61F2250/0039 ,  D04C1/06 ,  D04C3/48 ,  D04C7/00 ,  D10B2509/06 ,  Y10T29/49998

摘要： A mandrel for manufacturing a stent from a single wire includes a cylindrical member having a plurality of pins at a proximal end region, a plurality of pins at a distal end region, and a plurality of indentations between the proximal pins and the distal pins. These indentations form a helical pattern on the outer surface of the cylindrical member. The single wire is wrapped around every proximal pin and distal pin on the mandrel by following the indentations in the mandrel. The single wire is slid through the indentation under any crossing section of wire and over the next crossing section of wire in an under-over pattern.

摘要翻译： 用于从单线制造支架的心轴包括：在近端区域具有多个销的圆柱形构件，在远端区域处的多个销以及近端销和远端销之间的多个凹口。 这些凹陷在圆柱形构件的外表面上形成螺旋形图案。 通过跟随心轴中的凹陷将单根线缠绕在心轴上的每个近端销和远端销上。 单根导线在导线的任何交叉部分下滑过穿过凹陷，并且以下面的图案在导线的下一个交叉部分之上滑动。

公开(公告)号：US09126966B2

公开(公告)日：2015-09-08

申请号：US13599220

申请日：2012-08-30

申请人： Alan Martin ,  James Heyes ,  Mark Wood

发明人： Alan Martin ,  James Heyes ,  Mark Wood

IPC分类号： A61K9/14 ,  A61K9/127 ,  C07D319/06 ,  A61K47/28 ,  A61K47/22 ,  A61K31/713 ,  A61K9/51 ,  C12N15/88 ,  B82Y5/00 ,  A61K48/00

CPC分类号： C07D319/06 ,  A61K9/127 ,  A61K9/1272 ,  A61K9/14 ,  A61K9/5123 ,  A61K31/713 ,  A61K47/22 ,  A61K47/28 ,  A61K48/0033 ,  B82Y5/00 ,  C12N15/88 ,  Y10S977/773 ,  Y10S977/906 ,  Y10T428/2982

摘要： The present invention provides compositions and methods for the delivery of therapeutic agents to cells. In particular, these include novel cationic lipids and nucleic acid-lipid particles that provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid to cells in vivo. The compositions of the present invention are highly potent, thereby allowing effective knock-down of a specific target protein at relatively low doses. In addition, the compositions and methods of the present invention are less toxic and provide a greater therapeutic index compared to compositions and methods previously known in the art.

摘要翻译： 本发明提供了将治疗剂递送至细胞的组合物和方法。 特别地，这些包括提供核酸的有效包封的新型阳离子脂质和核酸 - 脂质颗粒，并将包封的核酸在体内有效递送至细胞。 本发明的组合物是高度有效的，从而允许以相对低的剂量有效击倒特异性靶蛋白。 此外，与本领域已知的组合物和方法相比，本发明的组合物和方法毒性低，并提供更大的治疗指数。

公开(公告)号：US08865675B2

公开(公告)日：2014-10-21

申请号：US13697000

申请日：2011-05-12

申请人： James Heyes ,  Mark Wood ,  Alan Martin ,  Amy C. H. Lee ,  Adam Judge ,  Marjorie Robbins ,  Ian MacLachlan

发明人： James Heyes ,  Mark Wood ,  Alan Martin ,  Amy C. H. Lee ,  Adam Judge ,  Marjorie Robbins ,  Ian MacLachlan

IPC分类号： C12N15/11 ,  C12Q1/68 ,  A61K31/713 ,  C12N15/88 ,  C12N15/113

CPC分类号： A61K31/713 ,  C12N15/111 ,  C12N15/113 ,  C12N15/88 ,  C12N2310/14 ,  C12N2320/32

摘要： The present invention provides compositions and methods for the delivery of interfering RNAs such as siRNAs that silence APOB expression in cells such as liver cells. In particular, the nucleic acid-lipid particles provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid to cells such as liver cells in vivo. The compositions of the present invention are highly potent, thereby allowing effective knock-down of APOB at relatively low doses. In addition, the compositions and methods of the present invention are less toxic and provide a greater therapeutic index compared to compositions and methods previously known in the art.

摘要翻译： 本发明提供用于递送干扰RNA的组合物和方法，例如在细胞如肝细胞中沉默APOB表达的siRNA。 特别地，核酸 - 脂质颗粒提供了核酸的有效包封，并且将体内核酸的活性有效地递送到细胞例如肝细胞。 本发明的组合物是非常有效的，从而允许以相对低的剂量有效地击倒APOB。 此外，与本领域已知的组合物和方法相比，本发明的组合物和方法毒性低，并提供更大的治疗指数。