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公开(公告)号:US20070142333A1
公开(公告)日:2007-06-21
申请号:US11670482
申请日:2007-02-02
申请人: John Lloyd , Yoon Jeon , Heather Finlay , Lin Yan , Michael Gross , Serge Beaudoin
发明人: John Lloyd , Yoon Jeon , Heather Finlay , Lin Yan , Michael Gross , Serge Beaudoin
IPC分类号: A61K31/55 , A61K31/541 , A61K31/5377 , A61K31/496 , A61K31/454 , A61K31/426 , A61K31/421 , C07D417/02 , C07D413/02 , C07D403/02
CPC分类号: C07D213/40 , A61K45/06 , C07C233/58 , C07C233/59 , C07C233/60 , C07C233/65 , C07C235/06 , C07C235/34 , C07C235/46 , C07C235/60 , C07C279/16 , C07C279/24 , C07C279/28 , C07C307/02 , C07C307/04 , C07C307/08 , C07C307/10 , C07C311/16 , C07C311/29 , C07C311/55 , C07C311/59 , C07C311/64 , C07C323/62 , C07C2601/02 , C07C2601/04 , C07C2601/10 , C07C2601/14 , C07C2602/08 , C07C2603/66 , C07D213/69 , C07D213/82 , C07D217/22 , C07D231/12 , C07D233/48 , C07D233/56 , C07D233/64 , C07D233/76 , C07D235/14 , C07D239/42 , C07D239/94 , C07D239/95 , C07D241/06 , C07D249/04 , C07D249/08 , C07D251/44 , C07D251/46 , C07D261/08 , C07D261/14 , C07D271/06 , C07D295/13 , C07D295/185 , C07D295/215 , C07D295/26 , C07D307/68 , C07D309/04 , C07D309/08 , C07D333/20 , C07D333/28 , C07D333/38 , C07D333/58 , C07D333/62 , C07D409/12 , C07D413/12 , C07D471/04 , C07D487/04
摘要: Novel cycloalkyl compounds useful as inhibitors of potassium channel function (especially inhibitors of the Kv1 subfamily of voltage gated K+ channels, especially inhibitors Kv1.5 which has been linked to the ultra-rapidly activating delayed rectifier K+ current IKur), methods of using such compounds in the prevention and treatment of arrhythmia and IKur-associated conditions, and pharmaceutical compositions containing such compounds.
摘要翻译: 可用作钾通道功能抑制剂的新型环烷基化合物(特别是电压门控K +通道抑制剂,尤其是抑制剂K + > 1.5,其与超快速活化延迟整流器K +电流I K连接),使用这些化合物在预防和治疗心律失常中的方法, 相关条件和含有这些化合物的药物组合物。
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32.
公开(公告)号:US20060216101A1
公开(公告)日:2006-09-28
申请号:US11375344
申请日:2006-03-15
申请人: Juergen Bosch , Michael Gross
发明人: Juergen Bosch , Michael Gross
IPC分类号: B41J29/00
CPC分类号: B60Q1/1469 , B60Q1/343 , B60Q9/00
摘要: A switching device in particular for a vehicle has a switching lever which can be deflected into different switching positions to activate switching processes. An actuator is driven by a control device to cause the switching lever to vibrate, the control device receiving input signals from at least one other control device and determines therefrom a set conditions for admissible deflection of the switching lever. The actuator is driven by the control device when the switching lever is deflected from a respective switching position into a switching position which does not meet the set conditions.
摘要翻译: 特别是用于车辆的开关装置具有可以偏转到不同切换位置以切换切换过程的切换杆。 致动器由控制装置驱动以使开关杆振动,控制装置接收来自至少一个其它控制装置的输入信号,并由此确定切换杆的容许偏转的设定条件。 当切换杆从相应的切换位置偏转到不满足设定条件的切换位置时,致动器由控制装置驱动。
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公开(公告)号:US20050049237A1
公开(公告)日:2005-03-03
申请号:US10286304
申请日:2002-11-01
申请人: Robert Atkinson , Michael Gross
发明人: Robert Atkinson , Michael Gross
IPC分类号: A61K31/4152 , A61K31/416 , A61K31/454 , A61K31/55 , C07D231/14 , C07D231/40 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07F5/02 , C07D43/02
CPC分类号: C07D231/14 , C07D231/40 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12
摘要: Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-dependent sodium channels. More particularly, the invention provides pyrazole-amides and -sulfonamides, compositions and methods that are useful in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrance of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a channel that includes a PN3 subunit.
摘要翻译: 提供的化合物,组合物和方法可用于通过电压依赖性钠通道抑制钠离子通量来治疗疾病。 更具体地,本发明提供了可用于治疗中枢性或周围神经系统疾病,特别是疼痛和慢性疼痛的吡唑酰胺和磺酰胺,组合物和方法,其通过阻断与指定条件的发作或复发有关的钠通道。 本发明的化合物,组合物和方法特别用于通过包含PN3亚基的通道抑制离子通量来治疗神经性或炎性疼痛。
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公开(公告)号:US06616221B2
公开(公告)日:2003-09-09
申请号:US10067133
申请日:2002-02-04
申请人: Karl-Heinz Lumpe , Michael Gross , Klaus Kolodzeij
发明人: Karl-Heinz Lumpe , Michael Gross , Klaus Kolodzeij
IPC分类号: B62D2507
摘要: A vehicle roof assembly includes a roof panel having longitudinal edges, each of which define a rim, structural bars disposed within and running along at least a portion of the rims, and frame rails running along at least a portion of each of the longitudinal edges. The rims abut the frame rails, and the structural bars are fixedly attached to the frame rails. Preferably, the rims are glued to the frame rails. The structural bars each include a web portion disposed between a contact surface abutting the roof panel, and a contact surface abutting the frame rails. Top-carriers including top-carrier cross braces are selectively attachable to the roof panel, and the structural bar. A roof liner is attached to a bottom surface of the roof panel, and an intermediate layer of plastic foam is disposed between the roof liner and the roof panel.
摘要翻译: 车顶组件包括具有纵向边缘的顶板,每个边缘限定边缘,设置在所述边缘的至少一部分内并沿着所述边缘的至少一部分延伸的结构杆以及沿着每个纵向边缘的至少一部分延伸的框架轨道。 轮辋邻接框架轨道,结构杆固定地附接到框架轨道。 优选地,轮缘胶合到框架轨道。 结构杆各自包括布置在抵靠屋顶板的接触表面之间的腹板部分和邻接框架轨道的接触表面。 包括顶部承载横梁的顶部承载件可选择性地附接到屋顶板和结构杆。 屋顶衬里附接到顶板的底表面,并且塑料泡沫的中间层设置在屋顶衬板和屋顶板之间。
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公开(公告)号:US06350095B1
公开(公告)日:2002-02-26
申请号:US09654129
申请日:2000-09-01
申请人: Michael Gross , Thomas Stertkamp
发明人: Michael Gross , Thomas Stertkamp
IPC分类号: F16B2100
CPC分类号: B60R9/04
摘要: A sustainer for securing a roof rail to a vehicle surface, which does not require protrusions or bumps to be formed on the vehicle surface to prevent unwanted rotation of the sustainer during tightening of an external bolt onto the sustainer.
摘要翻译: 一种用于将车顶轨道固定到车辆表面的支撑器,其不需要在车辆表面上形成突起或凸起,以防止在将外部螺栓紧固到支撑器上期间持续者的不必要的旋转。
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公开(公告)号:USD448958S1
公开(公告)日:2001-10-09
申请号:US29135160
申请日:2001-01-08
申请人: Michael Gross
设计人: Michael Gross
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公开(公告)号:US20230290103A1
公开(公告)日:2023-09-14
申请号:US18119779
申请日:2023-03-09
申请人: Michael Gross , John Matthews , Jimmy Chow
发明人: Michael Gross , John Matthews , Jimmy Chow
CPC分类号: G06V10/225 , G06T7/0012 , G06T7/73 , G06V40/10
摘要: Apparatus, systems and methods for measuring changes in the volume of a tissue of a person are described herein. The methods include applying a first marker to a portion of a tissue, the first marker having a pattern of markings thereon, each marking of the pattern of markings having an initial position; capturing an image of the pattern of markings at a first time after applying the first marker to the tissue, at least one marking of the pattern of markings having a subsequent position at the first time when the image is captured; determining a change of position of the at least one marking by comparing the subsequent position of the at least one marking in the captured image to the initial position of the at least one marking; and based on the change of position of the at least one marking, determining the physiological measurement of the tissue.
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38.
公开(公告)号:US20210069390A1
公开(公告)日:2021-03-11
申请号:US16960121
申请日:2019-01-09
申请人: Michael Gross
发明人: Michael Gross
摘要: Systems and methods for monitoring wound closure are described herein. The systems include a dressing for applying to a wound. The dressing includes an elasticized membrane having a first side and a second side and a reference object disposed on the first side. The elasticized membrane is movable between a relaxed state where the reference object has a first configuration and a stretched state where the reference object has a second configuration, the second configuration corresponding to an amount of swelling of an area of skin around the wound. The systems also include a camera for capturing an image of the reference object in the second configuration and a processor for comparing the image to a stored image of the reference object in the first configuration and determining a degree of swelling of the area of skin around the wound based on the comparison.
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公开(公告)号:US20180199102A1
公开(公告)日:2018-07-12
申请号:US15400944
申请日:2017-01-06
申请人: Michael Gross
发明人: Michael Gross
IPC分类号: H04N21/44 , H04N21/231 , H04N21/2187 , H04N21/262 , H04L12/58
摘要: Systems and methods are herein disclosed for displaying a smart preview of video content. A first claimed embodiment includes receiving video content. A system can then detect an event taking place during the video content having an event time. The system can then receive a request to display a preview of the video content. The system can then display the preview of the video content beginning at the event time.
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公开(公告)号:US08951161B2
公开(公告)日:2015-02-10
申请号:US13567691
申请日:2012-08-06
申请人: Thomas D. Koch , Justin Floro , Michael Gross , Kevin G. Meyer , Kevin J. Knox , James Rice , James Elmer Winzeler , Peter H. Hodges , Perry G. Cruce
发明人: Thomas D. Koch , Justin Floro , Michael Gross , Kevin G. Meyer , Kevin J. Knox , James Rice , James Elmer Winzeler , Peter H. Hodges , Perry G. Cruce
CPC分类号: F16H3/66 , F16H2200/0047 , F16H2200/0095 , F16H2200/2012 , F16H2200/2046
摘要: A compact five-speed transmission planetary gear train includes a first, second, third, and fourth planetary gear sets between an input and an output as well as first, second, and third brakes and first, second and third clutches. The first, second and third brakes and first, second and third clutches are selectively actuatable to provide five different forward speeds and a four different reverse speeds between the input and the output.
摘要翻译: 紧凑的五速变速器行星齿轮系包括在输入和输出之间的第一,第二,第三和第四行星齿轮组以及第一,第二和第三制动器以及第一,第二和第三离合器。 第一,第二和第三制动器和第一,第二和第三离合器可选择性地致动以在输入和输出之间提供五个不同的前进速度和四个不同的倒档速度。
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