Protein extraction methods
    3.
    发明授权
    Protein extraction methods 有权
    蛋白质提取方法

    公开(公告)号:US09580462B2

    公开(公告)日:2017-02-28

    申请号:US13223737

    申请日:2011-09-01

    申请人: Lin Yan Quanzhi Li

    发明人: Lin Yan Quanzhi Li

    IPC分类号: C07K1/34 C12N1/06 C07K1/00

    CPC分类号: C07K1/34

    摘要: The present invention relates to methods for isolating polypepitdes from cells. The methods may be used to isolate denatured polypeptides or native polypeptides. In one embodiment the methods may be used to isolated polypeptide from cytosolic and nuclear compartments of eukaryotic cells. In one embodiment the methods may be used to isolate polypeptides from bacterial cells.

    摘要翻译: 本发明涉及从细胞中分离多肽的方法。 该方法可用于分离变性多肽或天然多肽。 在一个实施方案中,该方法可用于来自真核细胞的胞质和核隔室的分离的多肽。 在一个实施方案中,所述方法可用于从细菌细胞中分离多肽。

    Diazeniumdiolate cyclohexyl derivatives
    4.
    发明授权
    Diazeniumdiolate cyclohexyl derivatives 有权
    二氮烯二硫代环己基衍生物

    公开(公告)号:US09272987B2

    公开(公告)日:2016-03-01

    申请号:US14115139

    申请日:2012-04-27

    摘要: A compound having the structure or a pharmaceutically acceptable salt thereof, wherein R6 is hydrogen, —OH, —C1-6alkyl, —OC1-6alkyl, aryl, or halogen, or together with R7, forms an oxo group, or together with R7 and the atom to which they are attached, form a 5-7-membered carbocycle ring or a 5-7-membered heterocyclic ring having 1, 2, or 3 heteroatoms, wherein alkyl and aryl are unsubstituted or independently mono-, di-, or tri-substituted with R14; R7 is hydrogen, C1-6alkyl, —CF3, aryl, —O-aryl, —O—C1-6alkyl, —C(O)OC1-6alkyl, —C(R15R16)OH, a 5-7-membered heteroaryl having 1, 2, 3 or 4 nitrogen atoms, or halogen, or together with R6, forms an oxo group, or together with R6 and the atom to which they are attached, form a 5-7-membered carbocycle ring or a 5-7-membered heterocyclic ring having 1, 2, or 3 heteroatoms wherein alkyl, aryl and heteroaryl are unsubstituted or independently mono-, di- or tri-substituted with R14; R12 is hydrogen, C1-6alkyl, or —(CH2)1-2OH, or together with R13 and the nitrogen atom to which they are attached, form a 4- to 7-membered heterocyclic ring containing one nitrogen atom and 0 or 1 oxygen atoms, wherein said ring is unsubstituted or independently mono-, di- or tri-substituted with halogen or —C1-6alkyl; R13 is —C1-6alkyl or —(CH2)1-2OH, or together with R12 and the nitrogen atom to which they are attached, form a 4- to 7-membered heterocyclic ring containing one nitrogen atom and 0 or 1 oxygen atoms, wherein said ring is unsubstituted or independently mono-, di- or tri-substituted with halogen or —C1-6alkyl.

    摘要翻译: 具有结构或其药学上可接受的盐的化合物,其中R 6是氢,-OH,-C 1-6烷基,-OC 1-6烷基,芳基或卤素,或与R 7一起形成氧代基,或与R 7和 它们连接的原子形成5-7元碳环或具有1,2或3个杂原子的5-7元杂环,其中烷基和芳基是未取代的或独立地是单 - ,二 - 或 用R14三取代; R 7是氢,C 1-6烷基,-CF 3,芳基,-O-芳基,-O-C 1-6烷基,-C(O)OC 1-6烷基,-C(R 15 R 16)OH,5- ,2,3或4个氮原子,或卤素,或与R6一起形成氧代基团,或与R6及其连接的原子一起形成5-7元碳环或5-7元碳环, 其中烷基,芳基和杂芳基是未取代的或独立地被R 14取代或被二取代或三取代的杂环基; R 12是氢,C 1-6烷基或 - (CH 2)1-2 OH,或者与R 13和它们所连接的氮原子一起形成含有一个氮原子和0或1个氧的4-至7-元杂环 原子,其中所述环是未取代的或独立地被卤素或-C 1-6烷基单,二或三取代; R 13是-C 1-6烷基或 - (CH 2)1-2 OH,或与R 12和它们所连接的氮原子一起形成含有一个氮原子和0或1个氧原子的4-至7-元杂环, 其中所述环是未取代的或独立地被卤素或-C 1-6烷基单,二或三取代。

    TRI-AXIS ACCELEROMETER
    8.
    发明申请
    TRI-AXIS ACCELEROMETER 审中-公开
    三轴加速度计

    公开(公告)号:US20110303009A1

    公开(公告)日:2011-12-15

    申请号:US13015927

    申请日:2011-01-28

    IPC分类号: G01P15/125

    CPC分类号: G01P15/125 G01P15/18

    摘要: An tri-axis accelerometer is disclosed. The tri-axis accelerometer includes a mass, a first group of capacitance, a third group of capacitance being neighbor to the first group of capacitance. The mass defines an upper surface, a lower surface parallel to the upper surface and a side wall connecting the upper surface and the lower surface. The first group of capacitance includes a first movable electrode and the third group of capacitance includes a third movable electrode. The first movable electrode is perpendicular to the third movable electrode.

    摘要翻译: 公开了三轴加速度计。 三轴加速度计包括质量,第一组电容,第三组电容与第一组电容相邻。 该物体限定上表面,平行于上表面的下表面和连接上表面和下表面的侧壁。 第一组电容包括第一可移动电极,第三组电容包括第三可移动电极。 第一可动电极垂直于第三可移动电极。