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公开(公告)号：US20060172936A1
公开(公告)日：2006-08-03
申请号：US11212045
申请日：2005-08-25
申请人： Michael Hale , Clarence Andrews , Eric Furfine , Ronald Sherrill , Andrew Spaltenstein , Gregory Lowen
发明人： Michael Hale , Clarence Andrews , Eric Furfine , Ronald Sherrill , Andrew Spaltenstein , Gregory Lowen
IPC分类号： A61K38/17 , A61K31/70 , A61K31/325
CPC分类号： C07D213/30 , C07C311/48 , C07C311/49 , C07C2601/08 , C07C2601/14 , C07D215/48 , C07D235/06 , C07D235/26 , C07D235/30 , C07D235/32 , C07D241/42 , C07D243/04 , C07D265/02 , C07D277/30 , C07D307/20 , C07D309/06 , C07D309/12 , C07D309/22 , C07D319/06 , C07D401/12 , C07D405/12 , C07D407/12 , C07D413/06 , C07D417/12 , C07D493/04 , C07F9/6561
摘要： The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also relates to methods For inhibiting the activity of HIV aspartyl protease using the compounds of this invention and methods for screening compounds for anti-HIV activity.
摘要翻译： 本发明涉及一类新型的磺酰胺，它们是天冬氨酰蛋白酶抑制剂。 在一个实施方案中，本发明涉及以特定结构和物理化学特征为特征的新型HIV天冬氨酰蛋白酶抑制剂。 本发明还涉及包含这些化合物的药物组合物。 本发明的化合物和药物组合物特别适用于抑制HIV-1和HIV-2蛋白酶活性，因此可有利地用作针对HIV-1和HIV-2病毒的抗病毒剂。 本发明还涉及使用本发明化合物抑制HIV天冬氨酰蛋白酶活性的方法和用于筛选抗HIV活性化合物的方法。
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公开(公告)号：US11598502B1
公开(公告)日：2023-03-07
申请号：US17385423
申请日：2021-07-26
申请人： Michael Hale
发明人： Michael Hale
摘要： A lamp platform assembly for emitting at least one light beam in various patterns, directions or orientations may include multi-positional support platform. At least one lamp unit may be carried by the support platform. Each lamp unit may be selectively positional to direct an emitted light beam in a selected direction or orientation. At least one electrical system may electrically interface with the at least one lamp unit. The at least one electrical system may be configured to provide electrical power to the at least one lamp unit.
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公开(公告)号：US20160063762A1
公开(公告)日：2016-03-03
申请号：US14476642
申请日：2014-09-03
申请人： Joseph Van Den Heuvel , Ken Ouellette , Ben Sugden , Todd Omotani , Marcus Tanner , Greg Alt , Michael Hale , Jeff Sutherland
发明人： Joseph Van Den Heuvel , Ken Ouellette , Ben Sugden , Todd Omotani , Marcus Tanner , Greg Alt , Michael Hale , Jeff Sutherland
CPC分类号： G06T19/006 , G02B27/0093 , G02B27/0172 , G02B2027/0138 , G02B2027/014 , G02B2027/0178 , G06F3/011 , G06F3/147 , G06K9/52 , G06T7/70 , G09G5/14
摘要： Methods for managing content within an interactive augmented reality environment are described. An augmented reality environment may be provided to an end user of a head-mounted display device (HMD) in which content (e.g., webpages) may be displayed to the end user using one or more curved slates that are positioned on a virtual cylinder that appears body-locked to the end user. The virtual cylinder may be located around the end user with the end user positioned in the middle of the virtual cylinder such that the one or more curved slates appear to be displayed at the same distance from the end user. The position and size of each of the one or more curved slates may be controlled by the end user using head gestures and a virtual pointer projected onto the virtual cylinder.
摘要翻译： 描述了在交互式增强现实环境中管理内容的方法。 增强的现实环境可以被提供给头戴式显示设备（HMD）的最终用户，其中内容（例如，网页）可以使用位于虚拟圆筒上的一个或多个弯曲板来显示给终端用户， 出现身体锁定到最终用户。 虚拟圆柱体可以位于最终用户周围，终端用户位于虚拟圆柱体的中间，使得一个或多个弯曲的板岩似乎以与最终用户相同的距离显示。 一个或多个弯曲板条中的每一个的位置和尺寸可以由终端用户使用头部手势和投射到虚拟圆柱体上的虚拟指针来控制。
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公开(公告)号：US20100242154A1
公开(公告)日：2010-09-30
申请号：US12383741
申请日：2009-03-26
申请人： Michael Hale
发明人： Michael Hale
CPC分类号： A41D19/01558
摘要： A glove for gardening and other general utility uses is provided comprising a palm portion configured to substantially cover a user's palm and palm side surface of the user's fingers and thumb, and a back portion configured to substantially cover the back of a user's hand and back surface of the user's fingers and thumb. One or more gripping portions are provided on the palm portion, with the back portion and the gripping portion comprising the same design pattern. Alternatively, the back portion and the gripping portions may comprise different design patterns. The design pattern or patterns are intended to be aesthetically pleasing, with the pattern on the gripping portions also aiding in the functionality of the glove by improving gripping and dexterity.
摘要翻译： 提供了一种用于园艺和其他一般用途的手套，其包括构造成基本上覆盖使用者的手指和拇指的使用者的手掌和手掌侧表面的手掌部分，以及被配置为基本上覆盖使用者的手和背面的背部的后部 的用户手指和拇指。 一个或多个抓握部分设置在手掌部分上，后部和抓握部分包括相同的设计图案。 或者，后部和抓握部分可以包括不同的设计图案。 设计图案或图案旨在在美学上令人愉快，抓握部分上的图案还通过改进夹紧和灵巧来辅助手套的功能。
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公开(公告)号：US11564465B1
公开(公告)日：2023-01-31
申请号：US17376746
申请日：2021-07-15
申请人： Michael Hale
发明人： Michael Hale
摘要： A cane includes an integral light in the handle, a leg attachment strap, and a foot attaching stirrup. The cane includes a rod assembly and a stirrup assembly. In one embodiment, the rod assembly includes a rod being a uniform cylindrical structure that is adapted to extend the length of a user's leg. The handle is disposed at a top most end of the rod and includes the light being embedded therein to provide illumination to the front and rear of a user. The stirrup provides a means for a user to nestle their foot to provide proper support.
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公开(公告)号：US09116967B2
公开(公告)日：2015-08-25
申请号：US13210140
申请日：2011-08-15
申请人： Justin Michael Ford , Michael Hale
发明人： Justin Michael Ford , Michael Hale
IPC分类号： G06F17/30
CPC分类号： G06F17/3056
摘要： Methods and apparatus to interface an application to a database are disclosed. An example method includes determining a query used by an application that is to communicate with a database via a database driver. The query is tested on the database via the database driver. Such testing includes storing a query template when a received result of the query matches an expected result of the query. A database access framework is generated to interface between the application and the database driver based on the stored query template.
摘要翻译： 公开了将应用程序与数据库进行接口的方法和装置。 示例性方法包括确定应用程序使用的查询，以通过数据库驱动程序与数据库进行通信。 该查询通过数据库驱动程序在数据库上进行测试。 这种测试包括当查询的接收结果与查询的预期结果匹配时存储查询模板。 生成数据库访问框架，以便基于存储的查询模板在应用程序和数据库驱动程序之间进行接口。
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公开(公告)号：US20050146257A1
公开(公告)日：2005-07-07
申请号：US10752145
申请日：2004-01-06
申请人： Robert Trujillo , Roger Anderson , David Carlson , Michael Hale
发明人： Robert Trujillo , Roger Anderson , David Carlson , Michael Hale
CPC分类号： H01L21/67115 , H01K1/58
摘要： A halogen lamp assembly 20 for a substrate processing chamber 100 has a halogen lamp 22 and a ceramic heat sink monolith 24. The halogen lamp 22 includes a filament 28 and a pair of electrical connectors 30 encapsulated in an envelope 26 having a pinch seal end 34. The ceramic heat sink monolith 24 includes a block 38 and an array of spaced apart posts 40 projecting outwardly from the block 38. The block 38 includes a cavity 42 that has a recessed inner surface 44 shaped to mate with the pinch seal end 34 of the lamp 22 and an opening that allows the electrical connectors 30 of the halogen lamp 22 to pass through.
摘要翻译： 用于衬底处理室100的卤素灯组件20具有卤素灯22和陶瓷散热器整体24.卤素灯22包括细丝28和一对电连接器30，该电连接器30封装在具有夹紧密封端34的封套26中 陶瓷散热器整料24包括块38和从块38向外突出的间隔开的柱40的阵列。块38包括空腔42，凹部42具有凹陷的内表面44，该内表面44成形为与挤压密封端34配合 灯22和允许卤素灯22的电连接器30通过的开口。
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公开(公告)号：US6001435A
公开(公告)日：1999-12-14
申请号：US48422
申请日：1998-03-26
申请人： Serena Hardy , Michael Hale
发明人： Serena Hardy , Michael Hale
摘要： A decorative Christmas tree device is provided including a base. A post is coupled to the base and extended upwardly therefrom. At least one light is mounted to the post and base for illuminating upon the receipt of power. Further included is monofilament line for encompassing the post, base, and light. As such, the illumination of the light permeates through the line.
摘要翻译： 提供了一种装饰性的圣诞树设备，其包括底座。 柱连接到基部并从其向上延伸。 至少一个灯被安装到柱子和底座上，用于在接收到电力时进行照明。 还包括用于包围柱子，底座和光线的单丝线。 因此，光的照射透过线。
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