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    Fibrosis inhibitor
    33.
    发明授权
    Fibrosis inhibitor 有权
    纤维化抑制剂

    公开(公告)号：US08729086B2

    公开(公告)日：2014-05-20

    申请号：US12919885

    申请日：2009-02-26

    申请人： Koji Murakami ,  Takuya Toramoto

    发明人： Koji Murakami ,  Takuya Toramoto

    IPC分类号： A61K31/4965 ,  C07D241/02

    CPC分类号： C07D241/20 ,  A61K31/4965

    摘要： [Object] The main object of the present invention is to provide a fibrosis inhibitor.[Solving Means] The present invention relates to a fibrosis inhibitor containing the heterocyclic derivative represented by the following general formula (1) or a pharmaceutically acceptable salt thereof as an active ingredient; In the formula (1), R1 and R2 are the same or different and each represents an optionally substituted aryl; R3 and R4 are the same or different and each represents hydrogen atom or alkyl; R5 represents hydrogen atom, alkyl or halogen atom; Y represents N or N→O; A represents NR6, and R6 represents hydrogen atom, alkyl, etc.; D represents alkylene or alkenylene which is optionally substituted with hydroxy; E represents phenylene or a single bond; G represents O, S, etc.; and Q represents carboxy, alkoxycarbonyl, etc.

    摘要翻译： 本发明的主要目的在于提供纤维化抑制剂。 本发明涉及含有下述通式（1）表示的杂环衍生物或其药学上可接受的盐作为有效成分的纤维化抑制剂。 在式（1）中，R 1和R 2相同或不同，表示任选取代的芳基; R3和R4相同或不同，各自表示氢原子或烷基; R5代表氢原子，烷基或卤素原子; Y表示N或N→O; A表示NR6，R6表示氢原子，烷基等。 D表示任选被羟基取代的亚烷基或亚烯基; E表示亚苯基或单键; G代表O，S等; Q表示羧基，烷氧基羰基等。

    Communication control system, communication control method, call control server device, and call control program
    34.
    发明授权
    Communication control system, communication control method, call control server device, and call control program 有权
    通信控制系统，通信控制方式，呼叫控制服务器设备和呼叫控制程序

    公开(公告)号：US08700783B2

    公开(公告)日：2014-04-15

    申请号：US12996807

    申请日：2009-06-15

    申请人： Yoshiko Sueda ,  Masashi Toyama ,  Koji Murakami

    发明人： Yoshiko Sueda ,  Masashi Toyama ,  Koji Murakami

    IPC分类号： G06F15/16

    CPC分类号： H04M7/003 ,  G06Q30/02 ,  H04L12/14 ,  H04L12/1457 ,  H04L12/1485 ,  H04L65/1036 ,  H04L65/105 ,  H04L65/1069 ,  H04M15/00 ,  H04M15/63 ,  H04M15/8292

    摘要： Upon receipt of an access request from a Web terminal, a service providing server transmits a shop ID stored in an external information database to the Web terminal. When the shop ID is selected by the Web terminal, the service providing server acquires external connection destination information, and notifies a SIP proxy server of the information via the Web terminal. When notified of the information, the SIP proxy server identifies internal connection destination information in an internal information database, based on an IP address added at the time of the notification of the external connection destination information. After making a call to a telephone device with the use of the identified internal connection destination information, the SIP proxy server makes a call to the shop with the use of the external connection destination information. After that, the SIP proxy server establishes a connection between the telephone device and the shop.

    摘要翻译： 在从Web终端接收到访问请求时，服务提供服务器将存储在外部信息数据库中的商店ID发送到Web终端。 当由Web终端选择商店ID时，服务提供服务器获取外部连接目的地信息，并通过Web终端向SIP代理服务器通知该信息。 SIP代理服务器在通知该信息时，根据在通知外部连接目的地信息时添加的IP地址，在内部信息数据库中识别内部连接目的地信息。 在通过使用所识别的内部连接目的地信息对电话设备进行呼叫之后，SIP代理服务器通过使用外部连接目的地信息来呼叫商店。 之后，SIP代理服务器建立电话设备和商店之间的连接。

    Vehicle driving apparatus
    36.
    发明授权
    Vehicle driving apparatus 有权
    车辆驾驶装置

    公开(公告)号：US08170760B2

    公开(公告)日：2012-05-01

    申请号：US12746437

    申请日：2009-03-23

    申请人： Hiroshi Sato ,  Osamu Komeda ,  Sachio Toyora ,  Mitsuhiro Tabata ,  Koji Murakami ,  Junichi Morimura

    发明人： Hiroshi Sato ,  Osamu Komeda ,  Sachio Toyora ,  Mitsuhiro Tabata ,  Koji Murakami ,  Junichi Morimura

    IPC分类号： G06F19/00

    CPC分类号： B60W20/40 ,  B60K6/387 ,  B60K6/48 ,  B60K6/547 ,  B60W10/02 ,  B60W10/08 ,  B60W10/113 ,  B60W20/00 ,  F16H3/006 ,  F16H2063/3036 ,  F16H2200/0052 ,  Y02T10/6221 ,  Y10T74/19223

    摘要： A vehicle driving apparatus that can execute cranking of an internal combustion engine by transmitting a mechanical power from a rotor of a motor to an engine output shaft without executing an engaging/disengaging operation of a clutch. A driving apparatus of a hybrid vehicle includes a first speed change mechanism capable of receiving mechanical power from an engine output shaft by a first input shaft and transmitting the mechanical power to drive wheels, a second speed change mechanism capable of receiving the mechanical power from the engine output shaft and a rotor by a second input shaft engaged with the rotor and transmitting the mechanical power to the drive wheels, a first clutch capable of engaging the engine output shaft with the first input shaft, and a second clutch capable of engaging the engine output shaft with the second input shaft.

    摘要翻译： 一种车辆驾驶装置，其能够通过将来自电动机的转子的机械动力传递到发动机输出轴而不执行离合器的接合/分离操作来执行内燃机的起动。 混合动力车辆的驱动装置包括能够通过第一输入轴从发动机输出轴接收机械动力并将机械动力传递到驱动轮的第一变速机构，能够从所述第二变速机构接收来自所述第二变速机构的机械动力的第二变速机构， 发动机输出轴和转子通过与转子接合并将机械动力传递到驱动轮的第二输入轴，能够将发动机输出轴与第一输入轴接合的第一离合器和能够接合发动机的第二离合器 输出轴与第二输入轴。

    Wheel for vehicle
    37.
    发明授权
    Wheel for vehicle 有权
    车轮

    公开(公告)号：US08020945B2

    公开(公告)日：2011-09-20

    申请号：US12155246

    申请日：2008-05-30

    申请人： Kazuo Takeda ,  Tatsuya Oba ,  Tetsuya Arakawa ,  Koji Murakami ,  Kazuki Yamazaki

    发明人： Kazuo Takeda ,  Tatsuya Oba ,  Tetsuya Arakawa ,  Koji Murakami ,  Kazuki Yamazaki

    IPC分类号： B60B7/06

    CPC分类号： B60B7/14

    摘要： A wheel for vehicle includes a wheel body, a decorated member, and a visible space. The wheel body has a rim, a hub, and a plurality of spokes connecting the hub and the rim. The decorated member is made from resin, is disposed on a surface of at least one of the spokes, and is retained to the wheel body. The visible space is disposed between the decorated member and the one of the spokes at least, exhibits a height in an axial direction of the wheel body, and is visible from an axial outer side of the wheel body.

    摘要翻译： 用于车辆的车轮包括轮体，装饰构件和可见空间。 轮体具有轮辋，轮毂和连接轮毂和轮辋的多个辐条。 装饰构件由树脂制成，设置在至少一个辐条的表面上，并被保持在轮体上。 所述可视空间至少设置在所述装饰构件和所述一个所述辐条之间，在所述车轮主体的轴向方向上具有高度，并且从所述车轮主体的轴向外侧可见。

    SERVICE PROVIDING SYSTEM AND SERVICE PROVIDING METHOD
    38.
    发明申请
    SERVICE PROVIDING SYSTEM AND SERVICE PROVIDING METHOD 有权
    服务提供系统和服务提供方法

    公开(公告)号：US20110196978A1

    公开(公告)日：2011-08-11

    申请号：US13123133

    申请日：2009-10-16

    申请人： Masashi Toyama ,  Koji Murakami ,  Yoshiko Sueda

    发明人： Masashi Toyama ,  Koji Murakami ,  Yoshiko Sueda

    IPC分类号： G06F15/16

    CPC分类号： H04L65/1069 ,  G06Q30/06 ,  H04L65/1006 ,  H04L65/4023 ,  H04L67/02 ,  H04L67/22

    摘要： A service providing server collects call session information that identifies communication established between terminals and service usage IDs that identify the terminals for each terminal. Then, the service providing server identifies call session information pieces indicating the same communication and associates Web services with each other. When the service providing server provides the associated Web services to the terminals, the service providing server identifies service usage IDs that identify the terminals and control provision of the Web services so that each Web service is provided according to history information stored in a history information database in association with service usage IDs.

    摘要翻译： 服务提供服务器收集标识终端之间建立的通信和识别每个终端的终端的服务使用ID的呼叫会话信息。 然后，服务提供服务器识别表示相同通信的呼叫会话信息，并将Web服务相互关联。 当服务提供服务器向终端提供关联的Web服务时，服务提供服务器识别标识终端的服务使用ID并控制Web服务的提供，使得根据历史信息数据库中存储的历史信息提供每个Web服务 与服务使用ID相关联。

    Vehicle wheel
    39.
    发明授权
    Vehicle wheel 有权
    车轮

    公开(公告)号：US07841670B2

    公开(公告)日：2010-11-30

    申请号：US12656383

    申请日：2010-01-28

    申请人： Kazuo Takeda ,  Tomokazu Nishikawa ,  Daiichiro Kawashima ,  Tatsuya Oba ,  Tetsuya Arakawa ,  Koji Murakami ,  Kenichi Sakanoshita

    发明人： Kazuo Takeda ,  Tomokazu Nishikawa ,  Daiichiro Kawashima ,  Tatsuya Oba ,  Tetsuya Arakawa ,  Koji Murakami ,  Kenichi Sakanoshita

    IPC分类号： B60B7/06

    CPC分类号： B60B7/14 ,  B60B7/0053 ,  B60B7/04 ,  B60B7/06 ,  B60B7/063 ,  B60B7/066 ,  B60B7/08 ,  B60B7/18

    摘要： The degree of freedom in design is increased while maintaining strength by enabling a decorative member to be disposed without thinning a wheel main body.A wheel is made up of a wheel main body 1 which is made up of a rim portion 10 and a disc portion 11 and which has a vent hole 141 in the disc portion 11 and a decorative member 2 made from a resin which is held in at least the disc portion 11 and is observed from the vent hole 141. Since the decorative member 2 is observed in the vent hole 141, the wheel main body 1 including spoke portions 14 does not have to be thinned. In addition, since the design of the decorative member is observed in cooperation with the design of the disc portion 11, the degree of freedom in design is increased.

    摘要翻译： 通过使装饰构件能够在不使轮主体变薄的情况下进行设置，可以提高设计自由度，同时保持强度。 车轮由轮缘主体1构成，车轮主体1由轮辋部分10和盘部分11构成，并且在盘部分11中具有通气孔141，以及由树脂制成的装饰件2 至少是圆盘部分11，并且从通气孔141观察到。由于在通气孔141中观察到装饰件2，所以包括轮辐部分14的轮主体1不一定要变薄。 此外，由于与盘部11的设计配合观察装饰构件的设计，因此设计的自由度增加。

    BIS(TRIMETHYLSILYL)PHENYL COMPOUND OR SALT THEREOF, AND USE THEREOF
    40.
    发明申请
    BIS(TRIMETHYLSILYL)PHENYL COMPOUND OR SALT THEREOF, AND USE THEREOF 失效
    BIS（三甲基甲硅烷基）苯基化合物或其盐，及其用途

    公开(公告)号：US20100210591A1

    公开(公告)日：2010-08-19

    申请号：US12682097

    申请日：2008-10-10

    申请人： Yoshimitsu Suda ,  Hiromi Oshiumi ,  Koji Murakami

    发明人： Yoshimitsu Suda ,  Hiromi Oshiumi ,  Koji Murakami

    IPC分类号： A61K31/695 ,  C07F7/10

    CPC分类号： C07F7/0812 ,  C07F7/081

    摘要： The present invention provides a compound that exhibits an excellent antitumor effect and reduces side effects, such as skin disorders, of the existing retinoid by selectively activating on the nuclear receptor RARα, thereby possibly producing significant improvement of clinical profits. Specifically, the present invention provides a bis(trimethylsilyl)phenyl compound represented by Formula (I): wherein X is N or CH; Y is O or S; R1, R2, and R3 are the same or different and are hydrogen or lower alkyl; R4 and R5 are the same or different and are hydrogen, lower alkyl, or halogen; and a bond between a carbon atom to which R1 is attached and a carbon atom to which R2 is attached is a single bond or a double bond; or a salt thereof.

    摘要翻译： 本发明提供通过选择性活化核受体RARα而显示出优异的抗肿瘤效果并降低现有类视色素的副作用，例如皮肤病，从而可能显着改善临床利益。 具体地说，本发明提供由式（I）表示的双（三甲基甲硅烷基）苯基化合物：其中X是N或CH; Y为O或S; R1，R2和R3相同或不同，为氢或低级烷基; R4和R5相同或不同，为氢，低级烷基或卤素; 并且R 1所连接的碳原子和R 2所连接的碳原子之间的键为单键或双键; 或其盐。