公开(公告)号：US20240000317A1

公开(公告)日：2024-01-04

申请号：US18211354

申请日：2023-06-19

Applicant: Omni Medsci, Inc.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  G01J3/10 ,  G01J3/28 ,  G01J3/14 ,  G01J3/453 ,  G01J3/42 ,  G01J3/02 ,  G01N21/35 ,  G16H40/67 ,  G01N21/359 ,  A61B5/145 ,  G01N33/15 ,  G01N33/49 ,  G01N21/3563 ,  G01N21/39 ,  G01N33/02 ,  G01N33/44 ,  G01N21/88 ,  A61B5/1455 ,  G16Z99/00 ,  A61C19/04 ,  G01N21/3504

CPC classification number: A61B5/0088 ,  A61B5/0075 ,  G01J3/108 ,  G01J3/28 ,  G01J3/14 ,  G01J3/453 ,  G01J3/42 ,  A61B5/7257 ,  G01J3/0218 ,  G01N21/35 ,  G16H40/67 ,  G01N21/359 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/4547 ,  G01N33/15 ,  G01N33/49 ,  G01J3/2823 ,  G01N21/3563 ,  G01N21/39 ,  G01N33/02 ,  G01N33/442 ,  G01N21/88 ,  A61B5/6801 ,  A61B5/7405 ,  A61B5/742 ,  G01N33/025 ,  A61B5/1455 ,  G16Z99/00 ,  A61B5/7203 ,  A61C19/04 ,  G01J3/02 ,  G01N21/3504 ,  G01N2201/129 ,  H01S3/302

Abstract: A sensing system includes laser diodes with Bragg reflectors generating light having an initial light intensity and one or more near-infrared optical wavelengths. The laser diodes are modulated with a pulsed output with 0.5 to 2 nanosecond pulse duration. A beam splitter receives light from the laser diodes, splits the light into a received sample arm light directed to an object and a received reference arm light. A detection system includes a second lens and spectral filters in front of a photodiode array. The photodiode array is coupled to CMOS transistors and receives at least a portion of the received reference arm light and generates a reference detector signal. The detection system is synchronized with the laser diodes. A time-of-flight measurement is based on a comparison of the sample detector signal and the reference detector signal and measures a temporal distribution of photons in the received reflected sample arm light.

公开(公告)号：US20210137389A1

公开(公告)日：2021-05-13

申请号：US17135233

申请日：2020-12-28

Applicant: Omni Medsci, Inc.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  A61C19/04 ,  G16H40/67 ,  A61B5/145 ,  A61B5/1455 ,  G01J3/02 ,  G01J3/10 ,  G01J3/14 ,  G01J3/28 ,  G01J3/42 ,  G01J3/453 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/88 ,  G01N33/02 ,  G01N33/15 ,  G01N33/44 ,  G01N33/49

Abstract: A measurement system is provided with an array of laser diodes with one or more Bragg reflectors. At least a portion of the light generated by the array is configured to penetrate tissue comprising skin. A detection system configured to: measure a phase shift, and a time-of-flight, of at least a portion of the light from the array of laser diodes reflected from the tissue relative to the portion of the light generated by the array; generate one or more images of the tissue; detect oxy- or deoxy-hemoglobin in the tissue; non-invasively measure blood in blood vessels within or below a dermis layer within the skin; measure one or more physiological parameters based at least in part on the non-invasively measured blood; and measure a variation in the blood or physiological parameter over a period of time.

公开(公告)号：US20210038083A1

公开(公告)日：2021-02-11

申请号：US17078771

申请日：2020-10-23

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  G16H40/67 ,  G01J3/02 ,  G01J3/10 ,  G01J3/14 ,  G01J3/28 ,  G01J3/42 ,  G01J3/453 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/88 ,  G01N33/02 ,  G01N33/15 ,  G01N33/44 ,  G01N33/49

Abstract: A system for measuring one or more physiological parameters is provided with a wearable device that includes a light source comprising a driver and a plurality of semiconductor sources that generate an output optical light. The wearable device comprises: one or more lenses to receive at least a portion of the output optical light and to deliver a lens output light to tissue, and a detection system to receive at least a portion of the lens output light reflected from the tissue and to generate an output signal having a signal-to-noise ratio, and to be synchronized to the light source. The detection system comprises at least one analog to digital converter coupled to at least one spatially separated detector. The plurality of semiconductor sources comprises six light emitting diodes, and wherein the plurality of semiconductor sources and the plurality of spatially separated detectors are located on one or more arcs.

公开(公告)号：US20190150748A1

公开(公告)日：2019-05-23

申请号：US16241628

申请日：2019-01-07

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  G01J3/42 ,  G01N33/49 ,  G01J3/28 ,  G01N21/88 ,  G01J3/453 ,  G01N21/359 ,  A61B5/1455 ,  G01J3/02 ,  A61B5/145 ,  G01J3/14 ,  G01J3/10 ,  G01N33/15 ,  G16H40/67 ,  G01N33/02 ,  G01N33/44 ,  G01N21/35 ,  G01N21/39 ,  G01N21/3563

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302 ,  Y02A90/26

Abstract: A smart phone or tablet includes a first part having at least one laser diode configured to be pulsed, and a second part having at least one other laser diode, the laser diodes configured to generate near-infrared light, wherein at least some of the laser diodes comprise a distributed Bragg reflector, with some laser diode light directed to tissue including skin. An array of laser diodes generates near-infrared light and includes one or more distributed Bragg reflectors. An assembly in front of the array to forms light spots on the tissue. A first receiver includes detectors that receive light reflected from the tissue. An infrared camera generates data from light reflected from the tissue. The smart phone or tablet generates a two-dimensional or three-dimensional image or mapping using the infrared camera data, and includes a wireless receiver, a wireless transmitter, a display, a voice input module, and a speaker.

公开(公告)号：US20190056266A1

公开(公告)日：2019-02-21

申请号：US16028473

申请日：2018-07-06

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: G01J3/10 ,  H01S5/40 ,  G01J3/02 ,  G01J3/42 ,  G02B6/293 ,  G02F1/365 ,  H01S3/067 ,  H01S3/094 ,  H01S3/30 ,  G01B9/02 ,  H01S5/14 ,  H01S5/10 ,  H01S5/00 ,  H01S3/102 ,  G02F1/35

CPC classification number: G01J3/108 ,  G01B9/02091 ,  G01J3/0218 ,  G01J3/0245 ,  G01J3/42 ,  G01J2003/102 ,  G01J2003/423 ,  G02B6/29349 ,  G02F1/365 ,  G02F2001/3528 ,  G02F2202/32 ,  H01S3/06725 ,  H01S3/06754 ,  H01S3/094007 ,  H01S3/094069 ,  H01S3/094076 ,  H01S3/1024 ,  H01S3/302 ,  H01S5/0064 ,  H01S5/0085 ,  H01S5/0092 ,  H01S5/1092 ,  H01S5/146 ,  H01S5/4012 ,  H01S2301/085

Abstract: A spectroscopy system includes a light source having an input light source, including semiconductor diodes generating an input beam with a wavelength shorter than 2.5 microns. Cladding-pumped fiber amplifiers receive the input beam and form an amplified optical beam having a spectral width. A nonlinear element broadens the spectral width of the amplified optical beam to 100 nm or more through a nonlinear effect forming an output beam that is pulsed. A filter is coupled to at least one of a lens and a mirror that receives the output beam and delivers the filtered output beam to a sample. A detection system includes detectors configured to receive the output beam reflected or transmitted from the sample. The detection system is configured to use a lock-in technique with the pulsed output beam and the spectroscopy system is adapted to detect chemicals in the sample.

公开(公告)号：US20180317776A1

公开(公告)日：2018-11-08

申请号：US16029611

申请日：2018-07-08

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  G01J3/42 ,  A61B5/145 ,  A61B5/1455 ,  G01N21/359 ,  G01N21/39 ,  G01N33/49 ,  G01N21/88 ,  G01J3/02 ,  G01J3/10 ,  G01J3/14 ,  G01J3/28 ,  G01N21/3563 ,  G01N21/35 ,  G01N33/44 ,  G01N33/15 ,  G01N33/02 ,  G01J3/453 ,  G01J3/18 ,  G01J3/12 ,  G01M3/38 ,  G01N21/85 ,  G01N21/95 ,  H01S3/00 ,  H01S3/30 ,  H01S3/067

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A smart phone or tablet includes pulsed laser diodes generating light with near-infrared wavelengths between 700-2500 nanometers. First lenses direct light from the laser diodes to tissue. An array of pulsed laser diodes generates light with near-infrared wavelengths between 700-2500 nanometers. Second lenses form light from the array into spots directed on the tissue. An infrared camera synchronized to the laser diodes and the array generates data based on light reflected from the tissue. The smart phone or tablet generates a two-dimensional or three-dimensional image using the data from the infrared camera. The smart phone or tablet includes a wireless receiver, a wireless transmitter, a display, a voice input module, and a speaker.

公开(公告)号：US20180120280A1

公开(公告)日：2018-05-03

申请号：US15855201

申请日：2017-12-27

Applicant: Omni Medsci, Inc.

Inventor： Mohammed N. ISLAM

IPC: G01N33/15 ,  A61B5/00 ,  A61B5/1455 ,  A61B5/145 ,  G01J3/10 ,  G01J3/28 ,  G01J3/453 ,  G01N21/359 ,  G01N21/3563 ,  G01N21/39 ,  G01N21/88 ,  G01N33/02 ,  G01N33/44 ,  G01N33/49

CPC classification number: G01N33/15 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/0088 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/3504 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/88 ,  G01N33/02 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3513 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  H01S3/302

Abstract: A measurement system includes a light source having semiconductor sources configured to generate an input optical beam, a multiplexer configured form an intermediate optical beam from the input optical beam, fibers including a fused silica fiber configured to receive the intermediate optical beam and to form an output optical beam. The output optical beam comprises wavelengths between 700 and 2500 nanometers with a bandwidth of at least 10 nanometers. A measurement apparatus is configured to deliver the output beam to a sample to generate a spectroscopy output beam. A receiver is configured to receive and process the spectroscopy output beam to generate an output signal, wherein the receiver processing includes chemometrics or multivariate analysis methods to permit identification of materials within the sample, the light source and the receiver are remote from the sample, and the sample includes plastics or food industry goods.

公开(公告)号：US20170367585A1

公开(公告)日：2017-12-28

申请号：US15686198

申请日：2017-08-25

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  G01J3/10 ,  G01J3/28 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N33/49 ,  G01N33/44 ,  G01N33/15 ,  G01N33/02 ,  G01N21/88 ,  G01J3/453 ,  G01M3/38 ,  H01S3/30 ,  G01J3/14 ,  G01J3/18

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A wearable device for use with a smart phone or tablet includes LEDs for measuring physiological parameters by modulating the LEDs and generating a near-infrared multi-wavelength optical beam. At least one LED emits at a first wavelength having a first penetration depth and at least another LED emits at a second wavelength having a second penetration depth into tissue. The device includes lenses that deliver the optical beam to the tissue, which reflects the first and second wavelengths. A receiver is configured to capture light while the LEDs are off and while at least one of the LEDs is on and to difference corresponding signals to improve a signal-to-noise ratio of the optical beam reflected from the tissue. The signal-to-noise ratio is further increased by increasing light intensity of at least one of the LEDs. The device generates an output signal representing a non-invasive measurement on blood within the tissue.

公开(公告)号：US20170336258A1

公开(公告)日：2017-11-23

申请号：US15662527

申请日：2017-07-28

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: G01J3/10 ,  G01J3/02 ,  G01J3/42 ,  G02B6/293 ,  G02F1/365 ,  H01S3/067 ,  H01S3/094 ,  H01S3/30 ,  G01B9/02 ,  H01S5/14 ,  H01S5/10 ,  H01S5/00 ,  H01S5/40 ,  H01S3/102 ,  G02F1/35

CPC classification number: G01J3/108 ,  G01B9/02091 ,  G01J3/0218 ,  G01J3/0245 ,  G01J3/42 ,  G01J2003/102 ,  G01J2003/423 ,  G02B6/29349 ,  G02F1/365 ,  G02F2001/3528 ,  G02F2202/32 ,  H01S3/06725 ,  H01S3/06754 ,  H01S3/094007 ,  H01S3/094069 ,  H01S3/094076 ,  H01S3/1024 ,  H01S3/302 ,  H01S5/0064 ,  H01S5/0085 ,  H01S5/0092 ,  H01S5/1092 ,  H01S5/146 ,  H01S5/4012 ,  H01S2301/085

Abstract: A super continuum light source includes an input light source having semiconductor diodes generating an input beam having a wavelength shorter than 2.5 microns. Optical amplifiers receive the input beam and form an amplified optical beam having a spectral width. The optical amplifiers may include a cladding-pumped fiber amplifier doped with rare-earth materials. A nonlinear element may include mid-infrared fibers to receive the amplified optical beam and to broaden the spectral width of the received amplified optical beam to 100 nm or more through a nonlinear effect forming an output beam, wherein the output beam is pulsed. At least a portion of the output beam is in a mid-infrared wavelength range between 2 microns and 5 microns and at least a portion of the one or more mid-infrared fibers comprises a ZBLAN fluoride fiber coupled to a chalcogenide fiber.

公开(公告)号：US20160363482A1

公开(公告)日：2016-12-15

申请号：US15248230

申请日：2016-08-26

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: G01J3/10 ,  G01J3/02 ,  G01B9/02 ,  H01S3/067 ,  H01S5/00 ,  H01S5/40 ,  H01S5/14 ,  H01S3/094 ,  G01J3/42 ,  G02F1/365

CPC classification number: G01J3/108 ,  G01B9/02091 ,  G01J3/0218 ,  G01J3/0245 ,  G01J3/42 ,  G01J2003/102 ,  G01J2003/423 ,  G02B6/29349 ,  G02F1/365 ,  G02F2001/3528 ,  G02F2202/32 ,  H01S3/06725 ,  H01S3/06754 ,  H01S3/094007 ,  H01S3/094069 ,  H01S3/094076 ,  H01S3/1024 ,  H01S3/302 ,  H01S5/0064 ,  H01S5/0085 ,  H01S5/0092 ,  H01S5/1092 ,  H01S5/146 ,  H01S5/4012 ,  H01S2301/085

Abstract: A white light spectroscopy system includes a super continuum light source having an input light source including semiconductor diodes to generate an input beam having a wavelength shorter than 2.5 microns. The light source includes a cladding-pumped fiber optical amplifier to receive the input beam, and a photonic crystal fiber to receive the amplified optical beam to broaden the spectral width to 100 nm or more forming an output beam in the visible wavelength range. The output beam is pulsed with a repetition rate of 1 Megahertz or higher. The system also includes a lens and/or mirror to receive the output beam, to send the output beam to a scanning stage, and to deliver the received output beam to a sample. A detection system includes dispersive optics and narrow band filters followed by one or more detectors to permit approximately simultaneous measurement of at least two wavelengths from the sample.

Abstract translation: 白光光谱系统包括具有包括半导体二极管的输入光源的超连续光源，以产生波长短于2.5微米的输入光束。 光源包括用于接收输入光束的包层泵浦光纤放大器，以及用于接收放大的光束以将光谱宽度扩大到100nm或更大的光子晶体光纤，形成可见波长范围内的输出光束。 输出光束以1兆赫或更高的重复频率脉冲。 该系统还包括用于接收输出光束的透镜和/或反射镜，以将输出光束发送到扫描级，并将接收的输出光束传送到样品。 检测系统包括色散光学器件和窄带滤光器，随后是一个或多个检测器，以允许从样品大致同时测量至少两个波长。