公开(公告)号：US20110054390A1

公开(公告)日：2011-03-03

申请号：US12585061

申请日：2009-09-02

申请人： Gary Searle ,  Keith N. Knapp ,  Roman Tunkel ,  Peter Skutnik ,  Lionel Vedrine

发明人： Gary Searle ,  Keith N. Knapp ,  Roman Tunkel ,  Peter Skutnik ,  Lionel Vedrine

IPC分类号： A61M5/168 ,  A61M5/142

CPC分类号： A61M5/158 ,  A61M5/1413 ,  A61M5/14212 ,  A61M5/14224 ,  A61M5/14248 ,  A61M5/16886 ,  A61M5/1723 ,  A61M5/3134 ,  A61M5/385 ,  A61M5/46 ,  A61M2005/14208 ,  A61M2005/14268 ,  A61M2005/1585 ,  A61M2005/16872 ,  A61M2205/16 ,  A61M2205/702 ,  A61M2209/045 ,  A61M2230/005 ,  A61M2230/201

摘要： Provided is an extended use self-contained, wearable medical device. The device is preferably configured with an infusion deployment mechanism for variably inserting and retracting an infusion needle to different depths, or completely retracting the infusion needle from the infusion site and then re-inserting the infusion needle after a predetermined period of time, throughout an infusion cycle for extending the viability of the infusion site. Another embodiment comprises dual needle deployment mechanisms which may also variably insert and retract the infusion needles. A flow sensor is preferably provided for detecting the stoppage of flow through the infusion cannula and signaling the needle deployment mechanism to attempt infusion at a different depth or to deploy a second infusion needle. A re-fillable reservoir assembly is preferably provided for supplying a drug over the extended use of the device. Another embodiment comprises a partially reusable and partially disposable medical device implementing the above features.

摘要翻译： 提供了一种扩展使用的独立的，可穿戴的医疗设备。 该装置优选地配置有输注展开机构，用于将输注针可变地插入和缩回到不同的深度，或者将输注针从输注部位完全缩回，然后在整个输注期间在预定时间段之后重新插入输注针 循环，以延长输注部位的生存能力。 另一个实施例包括双针展开机构，其也可以可变地插入和缩回输注针。 优选地设置流量传感器，用于检测通过输注套管的流动的停止并且发出针部署机构以尝试在不同深度输注或部署第二输注针。 优选地，可重新填充的储存器组件用于通过扩展使用该装置来供应药物。 另一实施例包括实现上述特征的部分可再利用和部分一次性医疗装置。

公开(公告)号：US20060151629A1

公开(公告)日：2006-07-13

申请号：US11347902

申请日：2006-02-06

申请人： Lionel Vedrine ,  Laurent Barrelle

发明人： Lionel Vedrine ,  Laurent Barrelle

IPC分类号： A62C11/00

CPC分类号： A61M15/0028 ,  A61M5/284 ,  A61M11/06 ,  B05B11/0083 ,  B05B11/02

摘要： A spray device including a barrel having a bypass and at least two spaced stoppers defining a first and second chambers and a spray nozzle. Movement of the first stopper drives the second stopper to the bypass and the fluid in the first chamber into the second chamber, mixing the fluid and substance. Continued movement of the first and second stoppers drives the mixture through the spray nozzle. The spray device may include a third stopper having a body in the tubular barrel which is moved toward the spray nozzle. The movement of the third stopper provides space for the mixture and prevents unpressurized fluid from flowing through the spray nozzle. The third stopper includes an axial stalk. The stalk may be deformable or the stalk may be separate from the body and the spray nozzle includes a longitudinal internal passage which provides communication with the spray port.

公开(公告)号：US07044125B2

公开(公告)日：2006-05-16

申请号：US10632603

申请日：2003-08-01

申请人： Lionel Vedrine ,  Hubert Jansen ,  Jean Pierre Grimard ,  Michel Guillory

发明人： Lionel Vedrine ,  Hubert Jansen ,  Jean Pierre Grimard ,  Michel Guillory

IPC分类号： A61M11/00 ,  A61M5/315

CPC分类号： B05B11/02 ,  A61M5/31591 ,  A61M11/06 ,  A61M15/0025 ,  A61M15/0065 ,  A61M15/08 ,  A61M2005/208 ,  A61M2205/073 ,  A61M2210/0618

摘要： A drug delivery system for administering preset doses of a substance such as a drug, vaccine or the like. The drug delivery system includes a holder and a pre-filled drug container such as a syringe which is retained in the holder. The drug container includes a barrel for containing the substance, a movable stopper situated within the barrel, and a blunt end having an opening through which the substance within the barrel can be expelled. The holder includes a distal portion and a proximal portion, each configured to accommodate the drug container, with the distal portion being able to be assembled to the proximal portion, which acts as a plunger rod during activation of the delivery system. A plurality of slots are provided on the holder that permit multiple equal doses of the substance to be administered to each nostril of the patient.

摘要翻译： 用于施用预先剂量的药物，疫苗等物质的药物递送系统。 药物输送系统包括保持器和保持在保持器中的诸如注射器的预填充药物容器。 药物容器包括用于容纳物质的桶，位于桶内的可移动止动件，以及具有开口的钝端，桶内的物质可以通过该开口排出。 保持器包括远端部分和近端部分，每个远端部分和近端部分被构造成容纳药物容器，远侧部分能够组装到近端部分，该近端部分在激活输送系统期间用作柱塞杆。 在保持器上设置多个槽，其允许向患者的每个鼻孔施用多个相等剂量的物质。

公开(公告)号：USD447559S1

公开(公告)日：2001-09-04

申请号：US29121338

申请日：2000-04-05

申请人： Hubert Jansen ,  Lionel Vedrine ,  Eric Denis ,  Samuel Bernier ,  Emmanuel Delarue

设计人： Hubert Jansen ,  Lionel Vedrine ,  Eric Denis ,  Samuel Bernier ,  Emmanuel Delarue

公开(公告)号：US20130006196A1

公开(公告)日：2013-01-03

申请号：US13516182

申请日：2009-12-16

申请人： Ralph Sonderegger ,  Corey Christensen ,  Lionel Vedrine

发明人： Ralph Sonderegger ,  Corey Christensen ,  Lionel Vedrine

IPC分类号： A61M5/315

CPC分类号： A61M5/2033 ,  A61M5/14244 ,  A61M5/14586 ,  A61M5/148 ,  A61M37/0015 ,  A61M2005/14506 ,  A61M2005/1585 ,  A61M2037/0023

摘要： A drug delivery device (100) includes a body (102, 116) having a reservoir (160) disposed therein for containing a medicament and an injection needle (152) for penetrating the skin of a patient, the needle (152) providing a path for the medicament between the reservoir (160) and the patient. The device (100) also includes a plunger (144) movable within the body (102, 116) for causing the medicament to be expelled from the reservoir (160), and a biasing means (140) for biasing the plunger (144) toward the reservoir (160), wherein in a pre-activated position, the biasing means (140) telescopes within itself, and upon activation, provides a force to the plunger (144) for expelling the medicament from the reservoir (160). The biasing means (140) is preferably provided in the form of a conical spring having a variable pitch.

摘要翻译： 药物输送装置（100）包括具有设置在其中的用于容纳药物的储存器（160）和用于穿透患者皮肤的注射针（152）的主体（102,116），所述针（152）提供路径 用于储存器（160）和患者之间的药物。 装置（100）还包括可在主体（102,116）内移动的柱塞（144），用于使药物从储存器（160）排出;以及偏置装置（140），用于将柱塞（144）朝向 所述储存器（160），其中在预启动位置中，所述偏置装置（140）在其内部望远镜，并且在启动时，向所述柱塞（144）提供用于从所述储存器（160）排出所述药物的力。 偏置装置（140）优选地以具有可变间距的锥形弹簧的形式设置。

公开(公告)号：US20130006195A1

公开(公告)日：2013-01-03

申请号：US13516169

申请日：2009-12-16

申请人： Ralph Sonderegger ,  Curt Bingham ,  Lionel Vedrine

发明人： Ralph Sonderegger ,  Curt Bingham ,  Lionel Vedrine

IPC分类号： A61M5/315

CPC分类号： A61M5/14244 ,  A61M5/14586 ,  A61M5/2033 ,  A61M2005/14506 ,  A61M2005/1585

摘要： A drug delivery device, including a body having a reservoir disposed therein for containing a medicament, the reservoir including a flexible wall; a plunger movable within the body for causing the medicament to be expelled from the reservoir, the plunger having a contact surface that is not affixed to said flexible reservoir wall; a spring biasing the plunger toward the reservoir; and means for selectively maintaining the plunger in a pre-activated position with respect to the reservoir and, upon releasing the plunger from the pre-activated position, for guiding the plunger to move under the force of the spring such that the contact surface of the plunger contacts the flexible reservoir wall to pressurize the reservoir for delivery of the medicament to a patient.

摘要翻译： 一种药物输送装置，包括其中设置有用于容纳药物的储存器的本体，所述储存器包括柔性壁; 柱塞，其可在所述主体内移动以使所述药物从所述储存器排出，所述柱塞具有未固定到所述柔性储存器壁的接触表面; 弹簧将柱塞偏压到储存器; 以及用于相对于所述储存器选择性地将所述柱塞保持在预启动位置并且在将所述柱塞从所述预启动位置释放时引导所述柱塞在所述弹簧的力作用下移动的装置， 柱塞接触柔性储存器壁以对储存器加压以将药物递送到患者。

公开(公告)号：US20120316506A1

公开(公告)日：2012-12-13

申请号：US13516540

申请日：2009-12-16

申请人： Ralph Sonderegger ,  Lionel Vedrine ,  Curt Bingham ,  Bart Peterson

发明人： Ralph Sonderegger ,  Lionel Vedrine ,  Curt Bingham ,  Bart Peterson

IPC分类号： A61M5/32

CPC分类号： A61M5/14248 ,  A61M5/14244 ,  A61M5/1626 ,  A61M5/3202 ,  A61M5/3213 ,  A61M2005/1416

摘要： A drug delivery device (100), including a body (104, 116) having a reservoir (164, 176) disposed therein for containing a medicament and an injection needle (152) for penetrating the skin of a patient, the needle (152) providing a path for the medicament between the reservoir (164, 176) and the patient. The device (100) also includes a needle cover (114) for selectively covering the injection needle (152), an adhesive (264) for selectively adhering the device to the patient, a release liner (500) for selectively covering a patient side of the adhesive (264), and a connecting means (112, 520, 512, 508, 524) for connecting the needle cover (114) and the release liner (500) such that removal of one of the needle cover (114) and the release liner (500) from the device (100) removes the other one of the needle cover (114) and the release liner (500).

摘要翻译： 一种药物输送装置（100），包括具有设置在其中的用于容纳药物的储存器（164,176）的主体（104,116）和用于穿透患者皮肤的注射针（152），所述针（152） 为储存器（164,176）和患者之间的药物提供路径。 装置（100）还包括用于选择性地覆盖注射针（152）的针罩（114），用于选择性地将装置粘附到患者的粘合剂（264），用于选择性地覆盖患者侧的剥离衬垫 粘合剂（264）和用于连接针罩（114）和释放衬垫（500）的连接装置（112,520,512,508,524），从而使针盖（114）和 脱离衬垫（500）从装置（100）移除针罩（114）和剥离衬垫（500）中的另一个。

公开(公告)号：US20120302966A1

公开(公告)日：2012-11-29

申请号：US13517496

申请日：2010-12-23

申请人： Lionel Vedrine

发明人： Lionel Vedrine

IPC分类号： A61M11/00

CPC分类号： A61M11/007 ,  A61M5/282 ,  A61M15/08 ,  B05B11/02

摘要： A delivery device for delivery of a medicament to a user including a container defining a reservoir storing the medicament, a body in which the container is received, a spray nozzle arranged on one of the body and the container for receiving medicament expelled from the container, and a pusher actuatable for pushing the medicament from the container reservoir through the nozzle, said pusher being movable from a rest position to a fully activated position relative to said body in response to an actuating force. The assembly is particularly applicable to nasal syringes where it is desirable to deliver the medicament in the form of a spray.

摘要翻译： 一种用于将药物输送给使用者的输送装置，包括限定储存药剂的容器的容器，容纳容器的容器，布置在主体和容器中的一个上的喷嘴，用于接收从容器中排出的药物， 以及推动器，其可致动以将药物从容器储存器推动通过喷嘴，所述推动器可响应于致动力而从静止位置相对于所述主体移动到完全启动位置。 该组件特别适用于需要以喷雾形式输送药物的鼻注射器。

公开(公告)号：US08262641B2

公开(公告)日：2012-09-11

申请号：US12537497

申请日：2009-08-07

申请人： Lionel Vedrine ,  Paul G. Alchas ,  Christopher N. Cindrich

发明人： Lionel Vedrine ,  Paul G. Alchas ,  Christopher N. Cindrich

IPC分类号： A61M5/32 ,  A61B19/00

CPC分类号： A61J1/2096 ,  A61J1/1406 ,  A61J1/201 ,  A61J1/2055 ,  A61M5/1782 ,  A61M2039/042

摘要： A filling system for syringes utilizing short needles to be filled from a vial having a thick septum is described. The system may be useful in any situation where the septum or vial stopper of a medication container is thicker than the usable length of the needle on the delivery device. Preferably, the syringe is filled just prior to use. The short needle includes an optional limiter which only permits a certain predetermined length of the needle cannula to protrude beyond the limiter a distance which limits penetration of the needle tip into both the skin and a vial stopper. The system and adapter may be useful for needles having a protrusion distance from approximately 0.5 mm to 3 mm, or any needle with a protrusion length shorter that the thickness of a septum to be accessed. Furthermore, a device is provided with shielding capabilities to shield the needle of the device.

摘要翻译： 描述了从具有厚的隔膜的小瓶中填充使用短针的注射器的填充系统。 在药物容器的隔膜或药瓶塞子比输送装置上的针的可用长度更厚的任何情况下，该系统可能是有用的。 优选地，注射器在使用之前被填充。 短针包括可选的限制器，其仅允许针套管的某个预定长度突出超过限制器一定距离，该距离限制针尖进入皮肤和药瓶塞子的穿透距离。 系统和适配器对于具有大约0.5mm至3mm的突出距离的针或具有比要访问的隔膜的厚度更短的突出长度的针可能是有用的。 此外，设备具有屏蔽能力以屏蔽设备的针。

公开(公告)号：US08070741B2

公开(公告)日：2011-12-06

申请号：US12534186

申请日：2009-08-03

申请人： Laurent Barrelle ,  Lionel Vedrine ,  Paul G. Alchas

发明人： Laurent Barrelle ,  Lionel Vedrine ,  Paul G. Alchas

IPC分类号： A61M31/00

CPC分类号： A61M5/326 ,  A61M2005/3247 ,  A61M2005/3261

摘要： A medical device is provided which includes a shield system and a syringe which is coupled to the shield system. The shield system includes a syringe holder and a shield which is slidably coupled to the holder. A spring resiliently urges the shield from a retracted position to an extended position. Stop members are provided on the holder and shield for maintaining the shield in the retracted position. The syringe is slidably coupled to the holder, and extends within the shield. Axial movement of the syringe with respect to the holder causes disengagement of the stop members, allowing the spring to move the shield to the extended position. Detents are provided on the holder for maintaining the shield in the extended position.

摘要翻译： 提供了一种医疗装置，其包括屏蔽系统和联接到屏蔽系统的注射器。 屏蔽系统包括注射器保持器和可滑动地联接到保持器的护罩。 弹簧弹性地将护罩从缩回位置推向延伸位置。 止动构件设置在保持器和护罩上，用于将护罩保持在缩回位置。 注射器可滑动地联接到保持器，并且在护罩内延伸。 注射器相对于保持器的轴向运动导致止动件的脱离，允许弹簧将护罩移动到延伸位置。 在保持器上设置有用于将护罩保持在延伸位置的凹处。