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    Extended Use Medical Device
    1.
    发明申请
    Extended Use Medical Device 有权
    延长使用医疗器械

    公开(公告)号：US20110054390A1

    公开(公告)日：2011-03-03

    申请号：US12585061

    申请日：2009-09-02

    申请人： Gary Searle ,  Keith N. Knapp ,  Roman Tunkel ,  Peter Skutnik ,  Lionel Vedrine

    发明人： Gary Searle ,  Keith N. Knapp ,  Roman Tunkel ,  Peter Skutnik ,  Lionel Vedrine

    IPC分类号： A61M5/168 ,  A61M5/142

    CPC分类号： A61M5/158 ,  A61M5/1413 ,  A61M5/14212 ,  A61M5/14224 ,  A61M5/14248 ,  A61M5/16886 ,  A61M5/1723 ,  A61M5/3134 ,  A61M5/385 ,  A61M5/46 ,  A61M2005/14208 ,  A61M2005/14268 ,  A61M2005/1585 ,  A61M2005/16872 ,  A61M2205/16 ,  A61M2205/702 ,  A61M2209/045 ,  A61M2230/005 ,  A61M2230/201

    摘要： Provided is an extended use self-contained, wearable medical device. The device is preferably configured with an infusion deployment mechanism for variably inserting and retracting an infusion needle to different depths, or completely retracting the infusion needle from the infusion site and then re-inserting the infusion needle after a predetermined period of time, throughout an infusion cycle for extending the viability of the infusion site. Another embodiment comprises dual needle deployment mechanisms which may also variably insert and retract the infusion needles. A flow sensor is preferably provided for detecting the stoppage of flow through the infusion cannula and signaling the needle deployment mechanism to attempt infusion at a different depth or to deploy a second infusion needle. A re-fillable reservoir assembly is preferably provided for supplying a drug over the extended use of the device. Another embodiment comprises a partially reusable and partially disposable medical device implementing the above features.

    摘要翻译： 提供了一种扩展使用的独立的，可穿戴的医疗设备。 该装置优选地配置有输注展开机构，用于将输注针可变地插入和缩回到不同的深度，或者将输注针从输注部位完全缩回，然后在整个输注期间在预定时间段之后重新插入输注针 循环，以延长输注部位的生存能力。 另一个实施例包括双针展开机构，其也可以可变地插入和缩回输注针。 优选地设置流量传感器，用于检测通过输注套管的流动的停止并且发出针部署机构以尝试在不同深度输注或部署第二输注针。 优选地，可重新填充的储存器组件用于通过扩展使用该装置来供应药物。 另一实施例包括实现上述特征的部分可再利用和部分一次性医疗装置。

    Extended use medical device
    2.
    发明授权
    Extended use medical device 有权
    延长使用医疗器械

    公开(公告)号：US09375529B2

    公开(公告)日：2016-06-28

    申请号：US12585061

    申请日：2009-09-02

    申请人： Gary Searle ,  Keith N Knapp ,  Roman Tunkel ,  Peter Skutnik ,  Lionel Vedrine

    发明人： Gary Searle ,  Keith N Knapp ,  Roman Tunkel ,  Peter Skutnik ,  Lionel Vedrine

    IPC分类号： A61M5/168 ,  A61M5/142 ,  A61M5/172 ,  A61M5/31 ,  A61M5/14 ,  A61M5/38 ,  A61M5/46 ,  A61M5/158

    CPC分类号： A61M5/158 ,  A61M5/1413 ,  A61M5/14212 ,  A61M5/14224 ,  A61M5/14248 ,  A61M5/16886 ,  A61M5/1723 ,  A61M5/3134 ,  A61M5/385 ,  A61M5/46 ,  A61M2005/14208 ,  A61M2005/14268 ,  A61M2005/1585 ,  A61M2005/16872 ,  A61M2205/16 ,  A61M2205/702 ,  A61M2209/045 ,  A61M2230/005 ,  A61M2230/201

    摘要： Provided is an extended use self-contained, wearable medical device. The device is preferably configured with an infusion deployment mechanism for variably inserting and retracting an infusion needle to different depths, or completely retracting the infusion needle from the infusion site and then re-inserting the infusion needle after a predetermined period of time, throughout an infusion cycle for extending the viability of the infusion site. Another embodiment comprises dual needle deployment mechanisms which may also variably insert and retract the infusion needles. A flow sensor is preferably provided for detecting the stoppage of flow through the infusion cannula and signaling the needle deployment mechanism to attempt infusion at a different depth or to deploy a second infusion needle. A re-fillable reservoir assembly is preferably provided for supplying a drug over the extended use of the device. Another embodiment comprises a partially reusable and partially disposable medical device implementing the above features.

    摘要翻译： 提供了一种扩展使用的独立的，可穿戴的医疗设备。 该装置优选地配置有输注展开机构，用于将输注针可变地插入和缩回到不同的深度，或者将输注针从输注部位完全缩回，然后在整个输注期间在预定时间段之后重新插入输注针 循环，以延长输注部位的生存能力。 另一个实施例包括双针展开机构，其也可以可变地插入和缩回输注针。 优选地提供流量传感器用于检测通过输注套管的流动的停止并且发出针部署机构以尝试在不同深度输注或部署第二输注针。 优选地，可重新填充的储存器组件用于通过扩展使用该装置来供应药物。 另一实施例包括实现上述特征的部分可再利用和部分一次性医疗装置。

    Flexible and Conformal Patch Pump
    3.
    发明申请
    Flexible and Conformal Patch Pump 审中-公开
    柔性和保形补片泵

    公开(公告)号：US20110054285A1

    公开(公告)日：2011-03-03

    申请号：US12585062

    申请日：2009-09-02

    申请人： Gary Searle ,  Keith N. Knapp ,  Peter Skutnik ,  Aidan Petrie ,  Dan Nelsen ,  Paul Brown

    发明人： Gary Searle ,  Keith N. Knapp ,  Peter Skutnik ,  Aidan Petrie ,  Dan Nelsen ,  Paul Brown

    IPC分类号： A61M5/142 ,  A61B5/00 ,  B23P11/00

    CPC分类号： A61M5/14244 ,  A61B5/14532 ,  A61B5/14542 ,  A61M5/16804 ,  A61M5/1723 ,  A61M2005/14252 ,  A61M2005/1583 ,  A61M2205/36 ,  Y10T29/49826

    摘要： Provided is a flexible and conformal wearable, self-contained medical device. The medical device comprises an integral housing formed by a flexible upper portion and a flexible lower portion joined along their perimeters. The medical device is also provided in a plurality of shapes and configurations for increasing the flexibility and conformability of the housing. The components contained within the housing, such as a drug reservoir, printed circuit board, and power supply are preferably constructed from flexible materials and are formed, connected and positioned according to the configuration of the housing in a manner for enhancing flexibility of the housing. A thermal bubble micropump is provided for controlling flow of a drug from the flexible reservoir, that utilizes a thermal resistor provided locally to a thermal expansion fluid that causes a surrounding membrane to expand and displace a volume of drug to be provided to the user.

    摘要翻译： 提供了一种柔性和适形的穿戴式，独立的医疗设备。 医疗装置包括由柔性上部部分和沿其周边连接的柔性下部部分形成的整体壳体。 医疗装置还设置有多个形状和构造，用于增加壳体的柔性和适应性。 包含在壳体内的诸如药物储存器，印刷电路板和电源的部件优选地由柔性材料构成，并且以提高壳体的柔性的方式根据壳体的构造形成，连接和定位。 提供了一种用于控制来自柔性储存器的药物流动的热泡微型泵，其利用局部地提供热膨胀流体的热电阻器，该热电阻器使周围的膜膨胀并移位一定量的待提供给使用者的药物。

    Flexible and conformal patch pump
    4.
    发明授权
    Flexible and conformal patch pump 有权

    公开(公告)号：US10092691B2

    公开(公告)日：2018-10-09

    申请号：US12585062

    申请日：2009-09-02

    申请人： Gary Searle ,  Keith N Knapp ,  Peter Skutnik ,  Aidan Petrie ,  Dan Nelsen ,  Paul Brown

    发明人： Gary Searle ,  Keith N Knapp ,  Peter Skutnik ,  Aidan Petrie ,  Dan Nelsen ,  Paul Brown

    IPC分类号： A61M37/00 ,  A61M5/142 ,  A61M5/168 ,  A61B5/145 ,  A61M5/172 ,  A61M5/158

    摘要： Provided is a flexible and conformal wearable, self-contained medical device. The medical device comprises an integral housing formed by a flexible upper portion and a flexible lower portion joined along their perimeters. The medical device is also provided in a plurality of shapes and configurations for increasing the flexibility and conformability of the housing. The components contained within the housing, such as a drug reservoir, printed circuit board, and power supply are preferably constructed from flexible materials and are formed, connected and positioned according to the configuration of the housing in a manner for enhancing flexibility of the housing. A thermal bubble micropump is provided for controlling flow of a drug from the flexible reservoir, that utilizes a thermal resistor provided locally to a thermal expansion fluid that causes a surrounding membrane to expand and displace a volume of drug to be provided to the user.

    PUMP ENGINE WITH METERING SYSTEM FOR DISPENSING LIQUID MEDICATION
    7.
    发明申请
    PUMP ENGINE WITH METERING SYSTEM FOR DISPENSING LIQUID MEDICATION 有权
    具有用于分配液体药物的计量系统的泵发动机

    公开(公告)号：US20140052096A1

    公开(公告)日：2014-02-20

    申请号：US13963748

    申请日：2013-08-09

    申请人： Gary Searle ,  Roman Tunkel ,  William Tormey III ,  Andrew Leonczyk ,  David Pollock ,  Paul Naumann ,  Kenneth Focht

    发明人： Gary Searle ,  Roman Tunkel ,  William Tormey III ,  Andrew Leonczyk ,  David Pollock ,  Paul Naumann ,  Kenneth Focht

    IPC分类号： A61M5/142

    CPC分类号： A61M5/14244 ,  A61M5/1452 ,  A61M5/16809 ,  A61M5/16881 ,  A61M2005/16863 ,  F04C2270/041

    摘要： An infusion pump system is disclosed for dispensing liquid medication, such as insulin. The infusion pump system includes a first reservoir for storing liquid medication, a first fluid driver for exerting pressure on the first reservoir, a second reservoir for storing liquid medication, and a second fluid driver for exerting pressure on the second reservoir. One or more valves are used to permit flow of liquid medication from the first reservoir to the second reservoir, and to permit flow of liquid medication from the second reservoir to an infusion site. Each of the valves is selectively opened or closed to fill the second reservoir with liquid medication from the first reservoir and to dispense liquid medication from the second reservoir to the infusion site. A controller and one or more sensors are used to monitor and control the system.

    摘要翻译： 公开了用于分配液体药物（例如胰岛素）的输注泵系统。 输液泵系统包括用于储存液体药物的第一储存器，用于在第一储存器上施加压力的第一流体驱动器，用于储存液体药物的第二储存器和用于在第二储存器上施加压力的第二流体驱动器。 一个或多个阀用于允许液体药物从第一储存器流动到第二储存器，并允许液体药物从第二储存器流动到输注部位。 选择性地打开或关闭每个阀，以从第一储存器用液体药物填充第二储存器，并将液体药物从第二储存器分配到输注部位。 控制器和一个或多个传感器用于监视和控制系统。

    LOW DOSE PREFILLED DRUG DELIVERY DEVICE AND METHOD
    8.
    发明申请
    LOW DOSE PREFILLED DRUG DELIVERY DEVICE AND METHOD 有权
    低剂量预制药物递送装置和方法

    公开(公告)号：US20130006216A1

    公开(公告)日：2013-01-03

    申请号：US13261383

    申请日：2011-01-31

    申请人： Margaret Taylor ,  James Bates ,  Roman Tunkel ,  Jay Butterbrodt ,  Gary Searle ,  Joshua Horvath ,  Keith Knapp, II ,  Edward Gillen

    发明人： Margaret Taylor ,  James Bates ,  Roman Tunkel ,  Jay Butterbrodt ,  Gary Searle ,  Joshua Horvath ,  Keith Knapp, II ,  Edward Gillen

    IPC分类号： A61M5/315 ,  A61M5/20 ,  A61M5/32

    CPC分类号： A61M5/2425 ,  A61M5/2459 ,  A61M5/3287 ,  A61M5/425 ,  A61M2005/005 ,  A61M2005/206

    摘要： A drug delivery device (100) for administering a low dose of a medicament includes a housing (111) and a drug reservoir (101) disposed in the housing (111). A needle (135) is connected to the drug reservoir (101). A pressure applying member (113) is movably connected to the housing (111) and is movable between first and second positions. The pressure applying member (113) does not apply pressure to the drug reservoir (101) in the first position and applies pressure to the drug reservoir (101) in the second position to dispense medicament stored in the drug reservoir (101). A method of administering a low dose of insulin to simulate a first-phase insulin response of a pancreas is also disclosed.

    摘要翻译： 用于施用低剂量药物的药物递送装置（100）包括设置在壳体（111）中的壳体（111）和药物储存器（101）。 针（135）连接到药物储存器（101）。 压力施加构件（113）可移动地连接到壳体（111）并且可在第一和第二位置之间移动。 压力施加构件（113）在第一位置不对药物储存器（101）施加压力，并且在第二位置向药物储存器（101）施加压力以分配存储在药物储存器（101）中的药物。 还公开了施用低剂量胰岛素以模拟胰腺的第一阶段胰岛素反应的方法。