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公开(公告)号:US20080172101A1
公开(公告)日:2008-07-17
申请号:US11933283
申请日:2007-10-31
申请人: Stephen L. Bolea , Robert S. Kieval , Bruce J. Persson , David J. Serdar , Peter T. Keith , Eric D. Irwin , Martin A. Rossing
发明人: Stephen L. Bolea , Robert S. Kieval , Bruce J. Persson , David J. Serdar , Peter T. Keith , Eric D. Irwin , Martin A. Rossing
IPC分类号: A61N1/00
CPC分类号: A61N1/3686 , A61N1/05 , A61N1/08 , A61N1/36117 , A61N1/36185
摘要: A system for stimulation, including an implantable pulse generator, a lead comprising an array body disposed at a distal end of the lead and a plurality of electrodes concentrically arranged on the array body, and a plurality of conductors, wherein one of the conductors is attached to each electrode and wherein the conductors are configured and arranged to couple the electrodes to the implantable pulse generator.
摘要翻译: 一种用于刺激的系统,包括可植入脉冲发生器,包括设置在引线的远端的阵列体的引线和同心地布置在阵列体上的多个电极,以及多个导体,其中一个导体被附接 并且其中所述导体被配置和布置成将所述电极耦合到所述可植入脉冲发生器。
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32.
公开(公告)号:US08855771B2
公开(公告)日:2014-10-07
申请号:US13205315
申请日:2011-08-08
IPC分类号: A61N1/36
CPC分类号: A61B5/0826 , A61B1/233 , A61B1/267 , A61B5/4552 , A61N1/0519 , A61N1/0551 , A61N1/3601 , A61N1/3611 , A61N1/36139
摘要: Devices and methods for treating obstructive sleep apnea by first performing an assessment of the patient that involves observing the patient's upper airway during a tongue protrusion maneuver. The assessment may, for example, be done using endoscopy to observe the upper airway while the patient is awake in the supine position. An adequate response of the upper airway during the tongue protrusion maneuver is indicative of likely therapeutic success with hypoglossal nerve stimulation, and may be used for making clinical decisions. The principles of the present invention may be applied to other therapeutic interventions for OSA involving the upper airway.
摘要翻译: 通过首先对患者的评估进行治疗阻塞性睡眠呼吸暂停的装置和方法,其涉及在舌突出动作期间观察患者的上呼吸道。 例如,可以使用内窥镜检查来观察患者在仰卧位时醒来时观察上呼吸道的评估。 在舌突出动作期间上呼吸道的充分反应表明舌下神经刺激可能具有治疗成功的作用,并可用于进行临床决策。 本发明的原理可以应用于涉及上呼吸道的OSA的其它治疗干预。
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公开(公告)号:US08718789B2
公开(公告)日:2014-05-06
申请号:US12762891
申请日:2010-04-19
申请人: Stephen L. Bolea , Robert S. Kieval , Bruce J. Persson , David J. Serdar , Peter T. Keith , Eric D. Irwin , Martin A. Rossing
发明人: Stephen L. Bolea , Robert S. Kieval , Bruce J. Persson , David J. Serdar , Peter T. Keith , Eric D. Irwin , Martin A. Rossing
IPC分类号: A61N1/00
CPC分类号: A61N1/36117 , A61B5/02028 , A61N1/05 , A61N1/0551 , A61N1/056 , A61N1/08 , A61N1/36053 , A61N1/3611 , A61N1/36114 , A61N1/36125 , A61N1/36135 , A61N1/36185 , A61N1/3702
摘要: Devices, systems and methods are described by which the blood pressure, nervous system activity, and neurohormonal activity may be selectively and controllably reduced by activating baroreceptors. A baroreceptor activation device is positioned near a baroreceptor, preferably a baroreceptor located in the carotid sinus. A control system may be used to modulate the baroreceptor activation device. The control system may utilize an algorithm defining a stimulus regimen which promotes long term efficacy and reduces power requirements/consumption. The baroreceptor activation device may utilize electrodes to activate the baroreceptors. The electrodes may be adapted for connection to the carotid arteries at or near the carotid sinus, and may be designed to minimize extraneous tissue stimulation.
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34.
公开(公告)号:US08718783B2
公开(公告)日:2014-05-06
申请号:US13327351
申请日:2011-12-15
CPC分类号: A61N1/3606 , A61B5/0809 , A61B5/4818 , A61B5/7239 , A61N1/0556 , A61N1/0558 , A61N1/3601 , A61N1/37229
摘要: A method of stimulating a hypogossal nerve including chronically implanting a nerve cuff electrode on a portion of the hypoglossal nerve. The method may further include sensing a signal corresponding to respiration and detecting expiratory onset from the sensed signal. Moreover, the method may include delivering a stimulus to the portion of the hypoglossal nerve via the nerve cuff electrode, wherein the stimulus is delivered as a function of the detected expiratory onset.
摘要翻译: 一种刺激低血压神经的方法,包括在舌下神经的一部分上长期植入神经袖带电极。 该方法还可以包括感测对应于呼吸的信号并且从感测信号检测呼气起始。 此外,该方法可以包括经由神经箍电极向舌下神经的部分递送刺激,其中作为检测到的呼气起始的函数递送刺激。
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公开(公告)号:US08676340B2
公开(公告)日:2014-03-18
申请号:US12954548
申请日:2010-11-24
申请人: Carl D. Wahlstrand , Gregory A. Hrdlicka , Thomas E. Cross, Jr. , Thomas Barry Hoegh , James M. Olsen , Stephen L. Bolea
发明人: Carl D. Wahlstrand , Gregory A. Hrdlicka , Thomas E. Cross, Jr. , Thomas Barry Hoegh , James M. Olsen , Stephen L. Bolea
IPC分类号: A61N1/05
CPC分类号: A61N1/08 , A61N1/05 , A61N1/0534 , A61N1/0553 , A61N1/086
摘要: A stimulation lead is configured to be implanted into a patient's body and includes at least one distal stimulation electrode and at least one conductive filer electrically coupled to the distal stimulation electrode. A jacket is provided for housing the conductive filer and providing a path distributed along at least a portion of the length of the lead for conducting induced RF energy from the filer to the patient's body.
摘要翻译: 刺激引线被配置为植入患者体内,并且包括至少一个远端刺激电极和至少一个电连接到远端刺激电极的导电滤波器。 提供外壳以容纳导电滤波器并且提供沿着引线长度的至少一部分分布的路径,以将感应的RF能量从滤波器传导到患者身体。
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公开(公告)号:US08620453B2
公开(公告)日:2013-12-31
申请号:US12954563
申请日:2010-11-24
IPC分类号: A61N1/05
CPC分类号: A61N1/08 , A61N1/05 , A61N1/0534 , A61N1/0551 , A61N1/086 , A61N1/36071
摘要: A medical lead is provided for use in a pulse stimulation system of the type which includes a pulse generator for producing electrical stimulation therapy. The lead comprises an elongate insulating body and at least one electrical conductor within the insulating body. The conductor has a proximal end configured to be electrically coupled to the pulse generator and has a DC resistance in the range of 375-2000 ohms. At least one distal electrode is coupled to the conductor.
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37.
公开(公告)号:US08498712B2
公开(公告)日:2013-07-30
申请号:US12980774
申请日:2010-12-29
IPC分类号: A61N1/36
CPC分类号: A61N1/3606 , A61B5/0809 , A61B5/4818 , A61B5/7239 , A61N1/0556 , A61N1/0558 , A61N1/3601 , A61N1/37229
摘要: A method of treating an upper airway of a patient. The method may include displacing a tongue of the patient while observing a response of the upper airway. The method may further include treating the upper airway based on the observed response, wherein treating the upper airway includes positioning an electrode adjacent a nerve innervating an upper airway muscle and delivering an electrical stimulation to the nerve to activate the upper airway muscle.
摘要翻译: 一种治疗患者上呼吸道的方法。 该方法可以包括在观察上呼吸道的响应的同时移位患者的舌头。 该方法可以进一步包括基于所观察到的反应来处理上呼吸道,其中治疗上气道包括定位邻近神经支配上呼吸道肌肉的神经的电极,并向神经传递电刺激以激活上呼吸道肌肉。
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公开(公告)号:US08386046B2
公开(公告)日:2013-02-26
申请号:US13251856
申请日:2011-10-03
IPC分类号: A61N1/36
CPC分类号: A61N1/3601 , A61B5/0809 , A61B5/0826 , A61B5/4818 , A61N1/0556 , A61N1/3611 , A61N1/36132 , A61N1/36139 , A61N1/3615 , A61N1/37235
摘要: Devices and methods for treating obstructive sleep apnea by first performing an assessment of the patient that involves observing the patient's upper airway during a tongue protrusion maneuver. The assessment may, for example, be done using endoscopy to observe the upper airway while the patient is awake in the supine position. An adequate response of the upper airway during the tongue protrusion maneuver is indicative of likely therapeutic success with hypoglossal nerve stimulation, and may be used for making clinical decisions. The principles of the present invention may be applied to other therapeutic interventions for OSA involving the upper airway.
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公开(公告)号:US08369965B2
公开(公告)日:2013-02-05
申请号:US12846547
申请日:2010-07-29
IPC分类号: A61N1/05
CPC分类号: A61N1/0553 , A61N1/0558
摘要: A medical system for electrical stimulation includes a first column of electrodes, a second column of electrodes, an expandable member disposed between first and second columns, and an expansion mechanism adapted to transmit an externally applied pressure to the expandable member. The pressure expands the expandable member in order to force the first column of electrodes apart from the second column of electrodes. The first and second columns, disposed side-by-side, may be inserted through a percutaneous needle and into a epidural space, alongside a spinal cord; after insertion, the first column may be forced apart from the second column by applying the pressure to the expandable member.
摘要翻译: 用于电刺激的医疗系统包括第一列电极,第二电极列,设置在第一和第二列之间的可扩张构件以及适于将外部施加的压力传递到可扩张构件的膨胀机构。 压力使可膨胀构件膨胀,以迫使第一列电极与第二列电极分开。 并排设置的第一和第二列可以穿过经皮针插入到与脊髓一起的硬膜外腔中; 在插入之后,通过向可膨胀构件施加压力,第一柱可以被迫离开第二柱。
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40.
公开(公告)号:US20120022626A1
公开(公告)日:2012-01-26
申请号:US13252028
申请日:2011-10-03
IPC分类号: A61N1/05
CPC分类号: A61N1/3606 , A61B5/0809 , A61B5/4818 , A61B5/7239 , A61N1/0556 , A61N1/0558 , A61N1/3601 , A61N1/37229
摘要: Devices, systems and methods for nerve stimulation for OSA therapy.
摘要翻译: 用于OSA治疗的神经刺激的装置,系统和方法。
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