7,2″-dehydrate puerarin and its salts, preparation method and use thereof
    34.
    发明授权
    7,2″-dehydrate puerarin and its salts, preparation method and use thereof 有权
    7,2“ - 脱水葛根素及其盐,其制备方法和用途

    公开(公告)号:US08436155B2

    公开(公告)日:2013-05-07

    申请号:US13177575

    申请日:2011-07-07

    CPC分类号: C07D493/14

    摘要: A 7,2″-dehydrate puerarin represented by formula (I) and salt derivatives thereof. The compounds are prepared from puerarin by intramolecular mitsunobu reaction. They are capable of shortening arrhythmia duration and prolonging coagulation time. They can be prepared into oral formulations or injections for treatment of cardiovascular and cerebrovascular diseases including arrhythmia, coronary heart disease, angina pectoris, myocardial infarction, and cerebral infarction.

    摘要翻译: 由式(I)表示的7,2“ - 脱水葛根素及其盐衍生物。 该化合物由葛根素通过分子内mitsunobu反应制备。 它们能够缩短心律失常持续时间并延长凝血时间。 它们可以制备成口服制剂或注射用于治疗心血管和脑血管疾病,包括心律失常,冠心病,心绞痛,心肌梗死和脑梗死。

    Dual Cation Dual Anion Coordination Complexes
    39.
    发明申请
    Dual Cation Dual Anion Coordination Complexes 有权
    双阳离子双阴离子配位络合物

    公开(公告)号:US20100184866A1

    公开(公告)日:2010-07-22

    申请号:US12651927

    申请日:2010-01-04

    IPC分类号: A61K31/09 C07C43/30

    CPC分类号: A61K31/194 C07C59/265

    摘要: Compounds are provided herein which are coordination complexes of the formula, AxByCit2Fz.mH2O, wherein A is a cation selected from certain IA or IIA metal ions in the Periodic Table; B is a cation selected from certain IIA metal ions and certain divalent d-block transition metal ions; A and B are different; “Cit” is tribasic citric acid anion; the stoichiometric ratio of x to y is equal or higher than 1.0 but lower than 8.0; m is 0-12; and z is selected such that electroneutrality is preserved. Compounds provided herein are useful to treat dietary deficiencies, osteoporosis, osteopenia, bone loss, and risk of bone loss, as well as other medical conditions involving the need for administration of the various ions. In addition, the compounds can be used as fluoride sources for dental use and to fluoridate water systems.

    摘要翻译: 本文提供了下式的配位络合物:AxByCit2Fz.mH2O,其中A是选自元素周期表中某些IA或IIA金属离子的阳离子; B是选自某些IIA金属离子和某些二价d嵌段过渡金属离子的阳离子; A和B不同; “Cit”是三元柠檬酸阴离子; x与y的化学计量比等于或高于1.0但低于8.0; m为0-12; 并且z被选择使得保持电中性。 本文提供的化合物可用于治疗饮食缺乏症,骨质疏松症,骨质减少,骨质流失和骨质流失的风险,以及涉及需要给予各种离子的其它医学病症。 此外,这些化合物可用作牙科用途的氟化物源,并且用于氟化水系统。

    Multi-energy static security CT system and imaging method

    公开(公告)号:US11789175B2

    公开(公告)日:2023-10-17

    申请号:US17302320

    申请日:2021-04-30

    IPC分类号: G01V5/00

    CPC分类号: G01V5/005

    摘要: A multi-energy static security CT system comprises at least one N-stage image chain structure (5) and a baggage conveying belt (4) provided at an inner side at the bottom of the N-stage image chain structure (5). The N-stage image chain structure (5) and the baggage conveying belt (4) are fixed at a pre-configured positions by means of a machine frame (8). The N-stage image chain structures (5) are sequentially arranged in a forward direction of a baggage channel, and adjacent N-stage image chain structures (5) are offset relative to each other. By exposing radiation sources in the N-stage image chain structure (5) at different times, the static security CT system generates an image having a higher temporal resolution and more energy spectrum levels than an image generated by a spiral CT system. Also provided is an imaging method implemented by means of the static security CT system.