摘要:
A reciprocating-piston internal combustion engine has a crank drive and a transmission lever indirectly coupled with the piston and intersecting the cylinder axis. The lever is articulated onto the crank drive's connecting rod and onto an adjustable bearing guided in the cylinder block. For greater variation of the translation of movements between crank drive and piston, the pulling and pushing rod connected with the piston has a guide at its end facing the transmission lever. The guide is preferably a pivotally-mounted slide shoe that engages into a guide extending along the transmission lever. The transmission lever is pivotally connected with the crankshaft connecting rod and connected with a setting drive for variably setting the articulation of the pulling and pushing rod on the transmission lever. A guide lever pivotally connected with the pulling and pushing rod and pivotally articulated onto the cylinder block guides the pulling and pushing rod.
摘要:
This invention relates to compounds of the formula wherein one of R5, R6 and R7 is and X1, X2, Y1 to Y4, R1 to R13 and m and n are defined in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.
摘要:
This invention relates to compounds of the formula wherein one of R6, R7 and R8 is and X, Y1 to Y4, R1 to R14 and n are as defined in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.
摘要:
A composition containing at least two of the following active substances A, B, C, wherein: A=at least one hormone stimulating the production of cAMP; B=at least one substance inhibiting the degradation of a cyclic nucleotide; C=at least one hormone stimulating the production of cGMP.
摘要翻译:含有至少两种以下活性物质A,B,C的组合物,其中:A =至少一种刺激cAMP产生的激素; B =抑制环状核苷酸降解的至少一种物质; C =至少一种刺激cGMP产生的激素。
摘要:
This invention relates to compounds of the formula wherein one of R5, R6 and R7 is and X1, X2, Y1 to Y4, R1 to R13 and m and n are defined in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.
摘要:
A shaft reactor for treating bulk material, including granular bulk material, in particular for the continuous post-condensation of PET, PEN or PA in the solid phase. A uniform product flow without significant decrease of the usable contents of the reactor and a decrease of the bulk pressure in the reactor is achieved by use of internals which are uncomplicated to fabricate. Internals are arranged in the reactor which comprise at least one ring and a plurality or ribs.
摘要:
A method for evaluating a measurement result of a thermal analysis. A program-controlled computer unit is used to calculate at least one probability of the agreement of the measurement result with at least one dataset previously stored in the computer unit, wherein this calculation is based on a comparison of effect data previously extracted from a measurement curve of the thermal analysis with corresponding stored effect data of the dataset. The evaluation can advantageously include, an automatic recognition and classification of measurement curves and can be carried out in particular more efficiently, more economically and more quickly than previously, with at the same time a high quality of evaluation.
摘要:
A method of manufacturing breadcrumbs, including the steps of forming a mixture, extruding the mixture to form loaves, surface drying the loaves in a first drying step, comminuting the loaves to form particles having a smaller size than the loaves, and further drying the particles in a second drying step to obtain the breadcrumbs.
摘要:
The invention relates to a valve train for internal combustion engines, comprising a camshaft and valve actuation elements for one or more valves, the elements being located in the cylinder head. The aim of the invention is to provide a valve train for an internal combustion engine, with which a reliable stroke adjustment of the valves can be made, without the need for complex technical resources, while at the same time allowing a forward or rear displacement of the valve orifice region. To achieve this, in order to modify the valve stroke curve, the contact point between the transfer member and the cam can be displaced along the periphery of the cam and the contact point between the transfer member and a control curve of the support body can be displaced, forcing the part of the transfer member that interacts with the cam to be guided, by shifting the transfer member in relation to the camshaft.
摘要:
This invention is concerned with compounds of the formula I: wherein one of R5, R6 and R7 is and X1, X2, R1 to R12, m, n and o are as defined in the description, and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.