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51 条记录 (耗时 0.031 秒)

    Pyrrolidinone, pyrrolidine-2,5-dione, pyrrolidine and thiosuccinimide derivatives, compositions and methods for treatment of cancer
    33.
    发明授权
    Pyrrolidinone, pyrrolidine-2,5-dione, pyrrolidine and thiosuccinimide derivatives, compositions and methods for treatment of cancer 有权
    吡咯烷酮，吡咯烷-2,5-二酮，吡咯烷和硫代琥珀酰亚胺衍生物，治疗癌症的组合物和方法

    公开(公告)号：US08304425B2

    公开(公告)日：2012-11-06

    申请号：US12664550

    申请日：2008-06-19

    申请人： Jianqiang Wang ,  Syed M. Ali ,  Eugene Kelleher ,  Yanbin Liu ,  Jason Hill ,  Mark A. Ashwell

    发明人： Jianqiang Wang ,  Syed M. Ali ,  Eugene Kelleher ,  Yanbin Liu ,  Jason Hill ,  Mark A. Ashwell

    IPC分类号： A01N43/42 ,  A61K31/44

    CPC分类号： C07D403/14

    摘要： The present invention relates to pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosucciniroide compounds of formulae (I)-(IV), and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosuccinimide compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound of pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosuccinimide compound of the present invention.

    摘要翻译： 本发明涉及式（I） - （IV）的吡咯烷-2-酮，吡咯烷-2,5-二酮，吡咯烷和硫代半胱氨酰化合物及其制备方法。 本发明还涉及包含吡咯烷-2-酮，吡咯烷-2,5-二酮，吡咯烷和硫代琥珀酰亚胺化合物的药物组合物。 本发明提供了治疗细胞增殖性疾病如癌症的方法，通过向有需要的受试者施用治疗有效量的吡咯烷-2-酮，吡咯烷-2,5-二酮，吡咯烷和硫代琥珀酰亚胺的化合物 本发明化合物。

    Scheduling a parallel job in a system of virtual containers
    34.
    发明授权
    Scheduling a parallel job in a system of virtual containers 有权

    公开(公告)号：US08869164B2

    公开(公告)日：2014-10-21

    申请号：US12874558

    申请日：2010-09-02

    申请人： Norman Bobroff ,  Liana Liyow Fong ,  Yanbin Liu ,  Seetharami R. Seelam

    发明人： Norman Bobroff ,  Liana Liyow Fong ,  Yanbin Liu ,  Seetharami R. Seelam

    IPC分类号： G06F9/455 ,  G06F9/46 ,  G06F9/50

    CPC分类号： G06F9/505 ,  G06F9/5077 ,  G06F2209/504 ,  Y02D10/22

    摘要： Methods and apparatus are provided for scheduling parallel jobs in a system of virtual containers. At least one parallel job is assigned to a plurality of containers competing for a total capacity of a larger container, wherein the at least one parallel job comprises a plurality of tasks. The assignment method comprises determining a current utilization and a potential free capacity for each of the plurality of competing containers; and assigning the tasks to one of the plurality of containers based on the potential free capacities and at least one predefined scheduling policy. The predefined scheduling policy may comprise, for example, one or more of load balancing, server consolidation, maximizing the current utilizations, minimizing a response time of the parallel job and satisfying quality of service requirements. The load balancing can be achieved, for example, by assigning a task to a container having a highest potential free capacity.

    ENERGY LIMIT IN A SLIDING WINDOW IN POWER AND HEAT MANAGEMENT
    37.
    发明申请
    ENERGY LIMIT IN A SLIDING WINDOW IN POWER AND HEAT MANAGEMENT 失效
    电力和热管理中的滑动窗口的能量限制

    公开(公告)号：US20110046804A1

    公开(公告)日：2011-02-24

    申请号：US12545711

    申请日：2009-08-21

    申请人： Liana L. Fong ,  Jeffrey Owen Kephart ,  Yanbin Liu

    发明人： Liana L. Fong ,  Jeffrey Owen Kephart ,  Yanbin Liu

    IPC分类号： G06F1/28

    CPC分类号： G06F1/3203 ,  G06F1/206 ,  G06F1/3296 ,  Y02D10/16 ,  Y02D10/172

    摘要： A system and method for specifying a temporal window of a fixed size that slides along time; specifying energy consumption as the accumulated power consumption in a temporal window; and applying a threshold that limits the energy consumption in a sliding window, while the power consumption can fluctuate within the window. Power-aware systems apply energy limit as a constraint in performance optimization.

    摘要翻译： 一种用于指定沿着时间滑动的固定尺寸的时间窗口的系统和方法; 将能量消耗指定为时间窗口中的累积功耗; 并且施加限制滑动窗口中的能量消耗的阈值，而功率消耗可以在窗口内波动。 功率感知系统将能量限制作为性能优化的约束。

    Scheduling a Parallel Job in a System of Virtual Containers
    39.
    发明申请
    Scheduling a Parallel Job in a System of Virtual Containers 审中-公开
    在虚拟容器系统中调度并行作业

    公开(公告)号：US20130024872A1

    公开(公告)日：2013-01-24

    申请号：US13609869

    申请日：2012-09-11

    申请人： Norman Bobroff ,  Liana Liyow Fong ,  Yanbin Liu ,  Seetharami R. Seelam

    发明人： Norman Bobroff ,  Liana Liyow Fong ,  Yanbin Liu ,  Seetharami R. Seelam

    IPC分类号： G06F9/46

    CPC分类号： G06F9/505 ,  G06F9/5077 ,  G06F2209/504 ,  Y02D10/22

    摘要： Methods and apparatus are provided for scheduling parallel jobs in a system of virtual containers. At least one parallel job is assigned to a plurality of containers competing for a total capacity of a larger container, wherein the at least one parallel job comprises a plurality of tasks. The assignment method comprises determining a current utilization and a potential free capacity for each of the plurality of competing containers; and assigning the tasks to one of the plurality of containers based on the potential free capacities and at least one predefined scheduling policy. The predefined scheduling policy may comprise, for example, one or more of load balancing, server consolidation, maximizing the current utilizations, minimizing a response time of the parallel job and satisfying quality of service requirements. The load balancing can be achieved, for example, by assigning a task to a container having a highest potential free capacity.

    摘要翻译： 提供了用于在虚拟容器系统中调度并行作业的方法和装置。 至少一个并行作业被分配给竞争大容器的总容量的多个容器，其中所述至少一个并行作业包括多个任务。 分配方法包括确定多个竞争容器中的每一个的当前利用率和潜在可用容量; 以及基于所述潜在可用容量和至少一个预定义的调度策略将所述任务分配给所述多个容器之一。 预定义的调度策略可以包括例如负载平衡，服务器整合中的一个或多个，最大化当前利用率，最小化并行作业的响应时间并满足服务质量要求。 例如，可以通过将任务分配给具有最高潜在空闲容量的容器来实现负载平衡。