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42 条记录 (耗时 0.048 秒)

    Composition for the Anti-Cancer Metastasis Containing DLK1-Fc Fusion Protein as an Effective Ingredient
    32.
    发明申请
    Composition for the Anti-Cancer Metastasis Containing DLK1-Fc Fusion Protein as an Effective Ingredient 有权
    含有DLK1-Fc融合蛋白作为有效成分的抗癌转移的组成

    公开(公告)号：US20130202592A1

    公开(公告)日：2013-08-08

    申请号：US13142818

    申请日：2010-04-13

    申请人： Young Woo Park ,  Kiwon Jo ,  Donghee Lee ,  Jung Yu ,  Ji Hyun Park ,  Chan-Woong Park ,  Eun Jin Kim ,  Yun Jung Park

    发明人： Young Woo Park ,  Kiwon Jo ,  Donghee Lee ,  Jung Yu ,  Ji Hyun Park ,  Chan-Woong Park ,  Eun Jin Kim ,  Yun Jung Park

    IPC分类号： C07K16/00 ,  C07K14/435

    CPC分类号： C07K16/00 ,  C07K14/435 ,  C07K14/475 ,  C07K2319/30 ,  Y10S424/809 ,  Y10S530/866

    摘要： A recombinant expression vector, comprising extracellular soluble domain genes of DLK1 and IgG antibody Fc domain genes, is constructed, and DLK1-Fc fusion protein is expressed and purified at 293E cell. The invention confirmed the efficacy as a drug for inhibiting cancer metastasis by confirming markedly reduced migration of cancer cells by DLK1-Fc fusion protein and also computing pharmacokinetic parameters. DLK1-Fc fusion protein has relatively higher stability than non-fusion protein, significantly reduces migration of various cancer cell lines, and provides superior cancer metastasis inhibition effect even at small concentration. Accordingly, DLK1-Fc fusion protein can be used efficaciously as an effective ingredient of a composition for inhibiting cancer metastasis.

    摘要翻译： 构建了包含DLK1和IgG抗体Fc结构域基因的细胞外可溶性域基因的重组表达载体，并且在293E细胞上表达和纯化DLK1-Fc融合蛋白。 本发明通过确认DLK1-Fc融合蛋白对癌细胞的迁移显着减少并且还计算药代动力学参数，证实了作为抑制癌症转移的药物的功效。 DLK1-Fc融合蛋白具有比非融合蛋白更高的稳定性，显着降低各种癌细胞系的迁移，即使在小浓度下也能提供优异的癌转移抑制作用。 因此，DLK1-Fc融合蛋白可以有效地用作抑制癌症转移的组合物的有效成分。

    USER INTERFACE DEVICE OF REMOTE CONTROL SYSTEM FOR ROBOT DEVICE AND METHOD USING THE SAME
    39.
    发明申请
    USER INTERFACE DEVICE OF REMOTE CONTROL SYSTEM FOR ROBOT DEVICE AND METHOD USING THE SAME 有权
    用于机器人装置的远程控制系统的用户界面装置及使用其的方法

    公开(公告)号：US20090157228A1

    公开(公告)日：2009-06-18

    申请号：US12336717

    申请日：2008-12-17

    申请人： Soon Hyuk Hong ,  Gi Oh Kim ,  Jong Ho Park ,  Ji Hyun Park ,  Seung Hyun Baek

    发明人： Soon Hyuk Hong ,  Gi Oh Kim ,  Jong Ho Park ,  Ji Hyun Park ,  Seung Hyun Baek

    IPC分类号： G05B15/00 ,  B25J19/04

    CPC分类号： B25J9/1689 ,  G05B2219/40161 ,  G05B2219/40165

    摘要： A user interface device of a remote control system for a robot and a method using the same are provided. The user interface device includes: a radio frequency (RF) unit for receiving, from a remote control robot, camera data and at least one sensor data detecting a distance; a display unit having a main screen and at least one auxiliary screen; and a controller having an environment evaluation module for determining whether the received camera data are in a normal condition, and having a screen display mode change module for displaying, if the received camera data are in a normal condition, the camera data on the main screen and displaying, if the received camera data are in an abnormal condition, the sensor data on the main screen.

    摘要翻译： 提供了一种用于机器人的远程控制系统的用户界面装置及其使用方法。 用户界面装置包括：射频（RF）单元，用于从遥控机器人接收摄像机数据和至少一个检测距离的传感器数据; 具有主屏幕和至少一个辅助屏幕的显示单元; 以及具有环境评估模块的控制器，所述环境评估模块用于确定所接收的相机数据是否处于正常状态，并且具有屏幕显示模式改变模块，用于如果接收到的相机数据处于正常状态，则显示主屏幕上的相机数据 并且如果接收到的相机数据处于异常状态，则在主屏幕上显示传感器数据。