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    SPIKE GENERATION CIRCUIT, INFORMATION PROCESSING CIRCUIT, POWER CONVERSION CIRCUIT, DETECTOR, AND ELECTRONIC CIRCUIT
    31.
    发明申请
    SPIKE GENERATION CIRCUIT, INFORMATION PROCESSING CIRCUIT, POWER CONVERSION CIRCUIT, DETECTOR, AND ELECTRONIC CIRCUIT 有权

    公开(公告)号：US20220014179A1

    公开(公告)日：2022-01-13

    申请号：US17408599

    申请日：2021-08-23

    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

    Inventor： Takeaki Yajima

    IPC: H03K3/02 ,  H03K5/01 ,  H03K19/20

    Abstract: A spike generation circuit includes a first CMOS inverter connected between a first power supply and a second power supply, an output node of the first CMOS inverter being coupled to a first node that is an intermediate node coupled to an input terminal to which an input signal is input, a switch connected in series with the first CMOS inverter, between the first power supply and the second power supply, a first inverting circuit that outputs an inversion signal of a signal of the first node to a control terminal of the switch, and a delay circuit that delays the signal of the first node, outputs a delayed signal to an input node of the first CMOS inverter, and outputs an isolated output spike signal to an output terminal.

    SUPERCONDUCTING COMPOUND QUANTUM COMPUTING CIRCUIT
    34.
    发明申请
    SUPERCONDUCTING COMPOUND QUANTUM COMPUTING CIRCUIT 有权

    公开(公告)号：US20210343785A1

    公开(公告)日：2021-11-04

    申请号：US17283037

    申请日：2019-10-31

    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

    Inventor： Yasunobu NAKAMURA ,  Yutak TABUCHI ,  Shuhei TAMATE

    IPC: H01L27/18 ,  H01L39/02 ,  H01L39/22 ,  G06N10/00

    Abstract: A superconducting complex quantum computing circuit includes a circuit substrate in which a wiring pattern of a circuit element including quantum bits and measurement electrodes, and ground patterns are formed, and through-electrodes connecting the ground pattern formed on a first surface of the substrate surface and the ground pattern formed on a second surface; a first ground electrode including a first contact portion in contact with the ground patterns, and a first non-contact portion having a shape corresponding to a shape of the wiring pattern; a second ground electrode including a second contact portion in contact with the ground pattern; a control signal line provided with a contact spring pin at a tip; and a pressing member that presses the first ground electrode against the first surface of the circuit substrate or presses the second ground electrode against the second surface of the circuit substrate.

    PHOTOACTIVATABLE TET EXPRESSION CONTROL SYSTEM
    35.
    发明申请
    PHOTOACTIVATABLE TET EXPRESSION CONTROL SYSTEM 有权

    公开(公告)号：US20210340548A1

    公开(公告)日：2021-11-04

    申请号：US17271037

    申请日：2019-08-30

    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

    Inventor： Itaru IMAYOSHI ,  Mayumi YAMADA ,  Yusuke SUZUKI ,  Shinji NAGASAKI

    IPC: C12N15/62 ,  C12N15/63 ,  C07K14/47

    Abstract: The present invention provides a photoactivatable Tet-OFF/ON system that can precisely control temporal and spatial gene expression. The present invention is a PA-Tet-OFF/ON system that includes a target gene expression cassette including a TRE having a TetO sequence, a promoter which is controlled by the TRE, and a target gene whose expression is controlled by the promoter; a first fusion protein expression cassette containing a gene which encodes a first fusion protein containing TetR or rTetR and a first protein; and a second fusion protein expression cassette containing a gene which encodes a second fusion protein containing p65AD and a second protein, in which the first protein and the second protein bind to each other to form a heterodimer only in a state of being irradiated with light at a specific wavelength.

    MEASURING DEVICE, CONTAINER DEVICE, AND MEASURING SYSTEM
    37.
    发明申请
    MEASURING DEVICE, CONTAINER DEVICE, AND MEASURING SYSTEM 有权

    公开(公告)号：US20210240014A1

    公开(公告)日：2021-08-05

    申请号：US17052583

    申请日：2019-05-15

    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

    Inventor： Kiichi Niitsu

    IPC: G02C11/00 ,  G02C7/04 ,  A61B5/00 ,  A61B5/145 ,  H04B5/00

    Abstract: The Present invention is a measuring system including a measuring device 10 that is attached to a living body, the measuring device 10 being configured to store information about an amount of electric power generated using sugars in a body fluid or bodily secretion of a living body, and a container device 15 for storing the measuring device 10, the container device 15 receiving the information about the amount of electric power generated, which is stored in the measuring device 10, using a near-field wireless communication method when the measuring device 10 is stored in the container device 15.

    BIOMARKER DETECTION METHOD, DISEASE ASSESSMENT METHOD, BIOMARKER DETECTION DEVICE, AND COMPUTER READABLE MEDIUM
    39.
    发明申请
    BIOMARKER DETECTION METHOD, DISEASE ASSESSMENT METHOD, BIOMARKER DETECTION DEVICE, AND COMPUTER READABLE MEDIUM 有权

    公开(公告)号：US20210158899A1

    公开(公告)日：2021-05-27

    申请号：US16612276

    申请日：2018-05-11

    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

    Inventor： LUONAN CHEN ,  KAZUYUKI AIHARA ,  XIAOPING LIU

    IPC: G16B40/00 ,  G16B50/30 ,  G16B30/10

    Abstract: Provided is a method for detecting a biomarker indicating states of a target biological system based on data acquired by measuring the target biological system. The method includes the steps of: preparing a reference dataset based on data acquired from one or more reference biological systems; generating a target dataset by adding, to the reference dataset, target biological data acquired from the target biological system; acquiring first correlation coefficients between a plurality of factor items in the reference dataset; acquiring second correlation coefficients between the plurality of factor items in the target dataset; acquiring difference correlation coefficients that are differences between the first correlation coefficients and the second correlation coefficients; acquiring indexes respectively for the plurality of factor items based on the difference correlation coefficients; and selecting the biomarker based on the indexes.

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