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    Intravascular treatment of lesions using magnetic nanoparticles
    31.
    发明授权
    Intravascular treatment of lesions using magnetic nanoparticles 有权
    使用磁性纳米粒子对病变进行血管内治疗

    公开(公告)号：US09138293B1

    公开(公告)日：2015-09-22

    申请号：US13952406

    申请日：2013-07-26

    Applicant: Brent Weisman

    Inventor： Brent Weisman

    IPC: A61M37/00 ,  A61B18/18 ,  B82Y5/00

    CPC classification number: A61B18/18 ,  A61B18/1815 ,  A61B2018/00404 ,  A61B2018/00416 ,  A61B2018/00577 ,  A61B2018/00982 ,  A61K9/0009 ,  A61K9/5094 ,  A61K9/5169 ,  A61M37/00 ,  A61N1/406 ,  B82Y5/00 ,  Y10S977/773 ,  Y10S977/908

    Abstract: Vascular lesions and plaque can be removed using a treatment based on introduction of magnetic nanoparticles into the circulatory system of a patient having such vascular lesions. The particles in an aqueous suspension are injected near the site of the lesion and magnetic forces are used to immobilize the particles in contact with the lesions. An alternating magnetic field or focused electromagnetic energy is then used to heat the particles, thereby destroying the lesion. Following destruction of the lesion, additional populations of magnetic particles having growth factors, anti-inflammatory agents and other medicaments on their surfaces can be localized at the site of the former lesion. These medicated particles accelerate healing at the site.

    Abstract translation: 可以使用基于将磁性纳米颗粒引入具有这种血管损伤的患者的循环系统中的治疗来除去血管损伤和斑块。 将水性悬浮液中的颗粒注射到损伤部位附近，并使用磁力来固定与病变接触的颗粒。 然后使用交变磁场或聚焦电磁能来加热颗粒，从而破坏病变。 在破坏病变之后，具有生长因子，抗炎剂和其他表面上的其它药物的磁性颗粒的额外群体可以位于前病变部位。 这些药物颗粒加速了现场的愈合。

    Polymer composites for biomedical applications and methods of making
    33.
    发明授权
    Polymer composites for biomedical applications and methods of making 有权
    用于生物医学应用的聚合物复合材料和制造方法

    公开(公告)号：US08771265B2

    公开(公告)日：2014-07-08

    申请号：US12797453

    申请日：2010-06-09

    Applicant: Csaba Truckai

    Inventor： Csaba Truckai

    IPC: A61B18/00 ,  A61B18/12 ,  A61B18/20

    CPC classification number: A61B17/12113 ,  A61B17/12022 ,  A61B17/12045 ,  A61B17/12118 ,  A61B17/12136 ,  A61B17/1214 ,  A61B17/12168 ,  A61B17/12181 ,  A61B17/12186 ,  A61B18/04 ,  A61B2017/12068 ,  A61B2017/12072 ,  A61B2018/00416 ,  A61B2018/00589 ,  D04H1/42 ,  Y10T428/249924

    Abstract: A biomedical polymer composite that exhibits ultra-low thermal conductivity properties. In a preferred embodiment, the biomedical polymer composite comprises a base polymer component with a dispersed thermally non-conductive filler component consisting of glass or ceramic nanospheres or microspheres that have a thermal conductivity of less than 5 W/m-K, and preferably less than 2 W/m-K. In one embodiment, the polymer composite has an electrically conductive filler and can be used in a filament for treating arteriovascular malformations. In another embodiment, the polymeric composite can be used as an energy-coupling means to apply energy to tissue.

    Abstract translation: 具有超低导热性能的生物医学聚合物复合材料。 在优选实施方案中，生物医学聚合物复合物包含具有分散的热不导电填料组分的基础聚合物组分，其由玻璃或陶瓷纳米球或微球组成，其热导率小于5W / mK，优选小于2W / mK。 在一个实施方案中，聚合物复合材料具有导电填料并可用于治疗动脉血管畸形的细丝。 在另一个实施方案中，聚合物复合材料可用作将能量施加到组织的能量耦合装置。

    METHOD AND APPARATUS FOR THROMBUS DISSOLUTION/THROMBECTOMY BY AN ELECTRODE CATHETER DEVICE
    36.
    发明申请
    METHOD AND APPARATUS FOR THROMBUS DISSOLUTION/THROMBECTOMY BY AN ELECTRODE CATHETER DEVICE 有权
    通过电极导管器件进行血栓溶解/血栓形成的方法和装置

    公开(公告)号：US20110301594A1

    公开(公告)日：2011-12-08

    申请号：US13127118

    申请日：2009-11-03

    Applicant: Itzhak Orion

    Inventor： Itzhak Orion

    IPC: A61B18/18

    CPC classification number: A61B18/1492 ,  A61B90/39 ,  A61B2018/00166 ,  A61B2018/00404 ,  A61B2018/0041 ,  A61B2018/00416 ,  A61B2018/00422 ,  A61B2018/00428 ,  A61B2018/0212 ,  A61B2018/1266 ,  A61B2018/1435

    Abstract: The present invention generally relates to a flexible catheter device capable of being introduced into body passages, withdraw fluids therefrom or introduce fluids thereinto, and which includes electrodes configured to apply electrical signals in the body passage for carrying out thrombus dissolution and/or thrombectomy, wherein one of said electrodes is designed to contact the thrombus material and remove it or dissolve it, and wherein the electrical voltage signals are a unipolar pulsatile voltage signal.

    Abstract translation: 本发明一般涉及一种能够被引入体通道中的柔性导管装置，从其中抽出流体或将流体引入其中，并且其包括被配置为在体通道中施加电信号以进行血栓溶解和/或血栓切除术的电极，其中 所述电极中的一个设计成接触血栓材料并将其去除或溶解，并且其中电压信号是单极脉冲电压信号。

    Polymer composites for biomedical applications and methods of making
    39.
    发明申请
    Polymer composites for biomedical applications and methods of making 有权
    用于生物医学应用的聚合物复合材料和制造方法

    公开(公告)号：US20040247849A1

    公开(公告)日：2004-12-09

    申请号：US10790987

    申请日：2004-03-02

    Inventor： Csaba Truckai

    IPC: D04H001/00

    CPC classification number: A61B17/12113 ,  A61B17/12022 ,  A61B17/12045 ,  A61B17/12118 ,  A61B17/12136 ,  A61B17/1214 ,  A61B17/12168 ,  A61B17/12181 ,  A61B17/12186 ,  A61B18/04 ,  A61B2017/12068 ,  A61B2017/12072 ,  A61B2018/00416 ,  A61B2018/00589 ,  D04H1/42 ,  Y10T428/249924

    Abstract: A biomedical polymer composite that exhibits ultra-low thermal conductivity properties. In a preferred embodiment, the biomedical polymer composite comprises a base polymer component with a dispersed thermally non-conductive filler component consisting of glass or ceramic nanospheres or microspheres that have a thermal conductivity of less than 5 W/mnullK, and preferably less than 2 W/mnullK. In one embodiment, the polymer composite is has an electrically conductive filler and can be used in a filament for treating arteriovascular malformations. In another embodiment, the polymeric composite can be used as an energy-coupling means to apply energy to tissue.

    Abstract translation: 具有超低导热性能的生物医学聚合物复合材料。 在优选实施方案中，生物医学聚合物复合物包含具有分散的热不导电填料组分的基础聚合物组分，其由玻璃或陶瓷纳米球或微球组成，其热导率小于5W / mK，优选小于2W / mK。 在一个实施方案中，聚合物复合材料具有导电填料并可用于治疗动脉血管畸形的细丝。 在另一个实施方案中，聚合物复合材料可用作将能量施加到组织的能量耦合装置。

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