公开(公告)号：US20060012797A1

公开(公告)日：2006-01-19

申请号：US11179765

申请日：2005-07-12

Applicant: Tiejun Chang ,  Mingzhen Tian ,  William Babbitt ,  Kristian Merkel

Inventor： Tiejun Chang ,  Mingzhen Tian ,  William Babbitt ,  Kristian Merkel

IPC: G01B9/02

CPC classification number: G01J3/02 ,  G01J3/0264 ,  G01J3/28 ,  G01J3/2889 ,  G01J3/4338 ,  G01J3/45

Abstract: Techniques for recovering optical spectral features include receiving a detected time series that represents a temporally varying intensity of an optical signal. The optical signal is formed in response to an interaction between a target optical spectrum and a chirped optical field. The chirped optical field is an optical field that has a monochromatic frequency that varies in time. The target optical spectrum is an optical frequency dependent optical property of a material or device. A phase correction factor is determined based only on one or more properties of the chirped optical field. The detected time series is corrected based on the phase correction factor to produce an output time series that reproduces in time a shape of the target spectrum in frequency. These techniques allow for fast measurement of spectral features and eliminate the need for prior knowledge of the target optical spectrum to adjust the chirp rate.

Abstract translation: 用于恢复光谱特征的技术包括接收表示时间上变化的光信号强度的检测时间序列。 响应于目标光谱和啁啾光场之间的相互作用形成光信号。 啁啾光场是具有随时间变化的单色频率的光场。 目标光谱是材料或器件的光学频率相关光学性质。 仅基于啁啾光场的一个或多个特性确定相位校正因子。 基于相位校正因子对所检测的时间序列进行校正，以产生在时间上再现目标频谱的形状的输出时间序列。 这些技术允许快速测量光谱特征，并且消除对目标光谱的先验知识的需要以调节啁啾率。

公开(公告)号：US06930775B1

公开(公告)日：2005-08-16

申请号：US10303172

申请日：2002-11-22

Applicant: Stevan M. Spremo ,  Peter L. Fuhr ,  John F. Schipper

Inventor： Stevan M. Spremo ,  Peter L. Fuhr ,  John F. Schipper

IPC: G01J3/18 ,  G01J3/28 ,  G01J3/36 ,  G01J3/457 ,  G01N21/64 ,  G01N21/77

CPC classification number: G01J3/18 ,  G01J3/2889 ,  G01J3/36 ,  G01J3/457 ,  G01N21/6408 ,  G01N21/645 ,  G01N21/77 ,  G01N2021/6463

Abstract: Method and system for wavelength-based processing of a light beam. A light beam, produced at a chemical or physical reaction site and having at least first and second wavelengths, λ1 and λ2, is received and diffracted at a first diffraction grating to provide first and second diffracted beams, which are received and analyzed in terms of wavelength and/or time at two spaced apart light detectors. In a second embodiment, light from first and second sources is diffracted and compared in terms of wavelength and/or time to determine if the two beams arise from the same source. In a third embodiment, a light beam is split and diffracted and passed through first and second environments to study differential effects. In a fourth embodiment, diffracted light beam components, having first and second wavelengths, are received sequentially at a reaction site to determine whether a specified reaction is promoted, based on order of receipt of the beams. In a fifth embodiment, a cylindrically shaped diffraction grating (uniform or chirped) is rotated and translated to provide a sequence of diffracted beams with different wavelengths. In a sixth embodiment, incident light, representing one or more symbols, is successively diffracted from first and second diffraction gratings and is received at different light detectors, depending upon the wavelengths present in the incident light.

Abstract translation: 光束波长处理方法及系统。 在化学或物理反应部位产生并具有至少第一和第二波长λ1和λ2的光束在第一衍射光栅处被接收和衍射，以提供第一和第二衍射光束，其被接收和分析为 波长和/或时间在两个间隔开的光检测器。 在第二实施例中，来自第一和第二源的光被衍射并且在波长和/或时间方面进行比较以确定两个光束是否源自相同的光源。 在第三实施例中，光束被分裂并衍射并通过第一和第二环境以研究差异效应。 在第四实施例中，具有第一和第二波长的衍射光束分量在反应位置被顺序地接收，以基于接收光束的顺序来确定是否促进指定的反应。 在第五实施例中，旋转并平移圆柱形衍射光栅（均匀或啁啾）以提供具有不同波长的衍射光束序列。 在第六实施例中，代表一个或多个符号的入射光从第一和第二衍射光栅连续衍射，并且根据存在于入射光中的波长在不同的光检测器处被接收。

公开(公告)号：US20040222378A1

公开(公告)日：2004-11-11

申请号：US10779959

申请日：2004-02-17

Inventor： Ralph Lance Carter ,  Robert Alan Hoult

IPC: G01J005/02

CPC classification number: G01J3/4535 ,  G01J3/06 ,  G01J3/2889 ,  G02B21/26

Abstract: An FT-IR microscope is operated in association with a scanning spectrometer in such a way that incremental movement of the movable stage of 5 the microscope is synchronized with the scans of the scanning spectrometer. This minimizes delays in processing time.

Abstract translation: 与扫描光谱仪相关联地操作FT-IR显微镜，使得显微镜的可移动台5的增量移动与扫描光谱仪的扫描同步。 这最大限度地减少了处理时间的延迟。

公开(公告)号：US20040169854A1

公开(公告)日：2004-09-02

申请号：US10376965

申请日：2003-02-28

Inventor： Tuan Vo-Dinh ,  Alan Wintenberg

IPC: G01N021/64 ,  G01N021/65

CPC classification number: G01J3/44 ,  G01J3/1256 ,  G01J3/2889 ,  G01N21/65 ,  G01N21/658 ,  G01N2021/656

Abstract: A scanning tunable detection system and related method for analyzing samples includes a source of time varying excitation signals and a tunable optical filter for selectively transmitting time-varying optical signals emanated from a sample following irradiation with the time varying excitation signals. A detector is provided for converting the time-varying optical signals to electrical detection signals. The system can identify components in a sample using phase sensitive or time sensitive detection. A slew scan mode can be used to permit slow scanning through spectral regions rich in information but quickly in regions without such information.

Abstract translation: 用于分析样本的扫描可调检测系统和相关方法包括时变激励信号源和可调谐光学滤波器，用于选择性地传输随时间变化的激发信号照射后从样品发出的时变光信号。 提供了用于将时变光信号转换为电检测信号的检测器。 该系统可以使用相敏或时间敏感检测来识别样品中的成分。 可以使用旋转扫描模式来允许在没有这种信息的区域中快速扫描富含信息的频谱区域，但是快速地扫描。

公开(公告)号：US20040031923A1

公开(公告)日：2004-02-19

申请号：US10637472

申请日：2003-08-08

Inventor： Scott T. Sanders

IPC: G01N021/35

CPC classification number: G01J3/2889 ,  G01J3/4338

Abstract: A high scan rate spectroscopic system converts a narrow-band laser pulse into a multispectral pulse, using, for example, a nonlinear fiber. The multispectral pulse is then converted to a swept frequency pulse through a second fiber impressing a frequency-dependent delay in the light beam which is then applied to the object to be tested.

Abstract translation: 高扫描速率光谱系统使用例如非线性光纤将窄带激光脉冲转换成多光谱脉冲。 然后，多光谱脉冲通过第二光纤转换成扫描频率脉冲，该第二光纤施加光束中的频率相关延迟，然后将其施加到待测对象。

公开(公告)号：US06163378A

公开(公告)日：2000-12-19

申请号：US332404

申请日：1999-06-14

Applicant: Jehad Khoury

Inventor： Jehad Khoury

IPC: G01J3/26 ,  G01J3/28 ,  G06K9/74 ,  G01B9/02

CPC classification number: G06K9/74 ,  G01J3/0259 ,  G01J3/26 ,  G01J3/2823 ,  G01J3/2889 ,  G01J2003/2866

Abstract: A spectrum analyzer for producing a first two-dimensional array of time varying spectral analysis image input signals, a reference image generator for producing a second two-dimensional array of spectral analysis image reference signals, and a time-integrative correlator, which can be non-coherent or coherent, or correlating the two groups of image representitive signals to determine the degree of matching between an input image and a library reference image. The spectrum analyzer can include an interferometer, a tunable optical filter, or a time-wavelength-multiplexing holographic lens for viewing the input image. A monolithic non-holographic version provides a rugged, compact and portable image analyzer for examining many types of images.

Abstract translation: 一种用于产生时变光谱分析图像输入信号的第一二维阵列的频谱分析仪，用于产生频谱分析图像参考信号的第二二维阵列的参考图像产生器，以及可以是非均匀性的时间积分相关器 相干或相干，或将两组图像表示信号相关联，以确定输入图像和库参考图像之间的匹配程度。 频谱分析仪可以包括用于观看输入图像的干涉仪，可调谐滤光器或时间波长复用全息透镜。 单片非全息版本提供坚固，紧凑和便携的图像分析仪，用于检查许多类型的图像。

公开(公告)号：US5899865A

公开(公告)日：1999-05-04

申请号：US484982

申请日：1995-06-07

Applicant: Britton Chance

Inventor： Britton Chance

IPC: G01N21/27 ,  A61B5/00 ,  A61B5/055 ,  A61B6/04 ,  A61B10/00 ,  G01J3/28 ,  G01N21/49 ,  G01N21/59 ,  A61B6/00

CPC classification number: A61B5/0091 ,  A61B5/14552 ,  A61B5/4312 ,  G01J3/2889 ,  G01N21/49 ,  G01N21/59 ,  G01N2021/1791 ,  G01N2021/4797

Abstract: A method of breast tissue examination using time-resolved spectroscopy includes the following steps. A support that includes an input port and an output port separated by a selected distance is positioned relative to the examined breast. Locations of the input and output ports are selected to examine a tissue region of the breast. Light pulses of a selected wavelength and duration less than a nanosecond are introduced into the breast tissue at the input port and detected over time at the detection port. Signals corresponding to photons of detected modified pulses are accumulated over time. Values of a scattering coefficient or an absorption coefficient of the examined breast tissue are calculated based on the shape of the modified pulses. The examined breast tissue is characterized based on the values of the scattering coefficient or the absorption coefficient. Absorbing or fluorescing contrast agents may be introduced into the examined tissue. This method may be used in conjunction with x-ray mammography, needle localization procedure or MRI mammography.

Abstract translation: 使用时间分辨光谱的乳腺组织检查方法包括以下步骤。 包括输入端口和分隔开所选距离的输出端口的支撑件相对于被检查的乳房定位。 选择输入和输出端口的位置以检查乳房的组织区域。 所选择的波长和持续时间小于纳秒的光脉冲被引入到输入端口处的乳房组织中，并在检测端口随时间检测。 对应于检测到的修改脉冲的光子的信号随时间累积。 基于修正脉冲的形状计算检查的乳房组织的散射系数或吸收系数的值。 基于散射系数或吸收系数的值来表征检查的乳腺组织。 吸收或荧光的造影剂可以被引入被检查的组织中。 该方法可以与x射线乳房X线照相术，针定位程序或MRI乳房X线摄影结合使用。

公开(公告)号：US4658218A

公开(公告)日：1987-04-14

申请号：US679782

申请日：1984-12-10

Applicant: Geraldine A. Kenney-Wallace ,  Edward L. Quitevis

Inventor： Geraldine A. Kenney-Wallace ,  Edward L. Quitevis

IPC: G01J3/28 ,  G04F13/02 ,  H01S3/094 ,  H01S3/098 ,  G03B9/70

CPC classification number: H01S3/1109 ,  G01J3/2889 ,  G04F13/026 ,  H01S3/094026 ,  H01S3/0912 ,  H01S3/11 ,  H01S3/213 ,  H01S3/2308

Abstract: A synchronization circuit couples a mode-locked oscillator-amplifier laser to a streak camera and Vidicon detection system. A sync signal from a mode-locker driver and a sync signal from a Nd:YAG pump laser act as basic circuit start signals. The circuit, with appropriate electronic timing delays, generates a Q-switch signal to the Nd:YAG laser to control the amplifier pump pulses to overlap with a dye laser pulse as it arrives in each stage of an optical amplifier chain.

Abstract translation: 同步电路将锁模振荡器放大器激光器连接到条纹相机和Vidicon检测系统。 来自模式锁定器驱动器的同步信号和来自Nd：YAG泵浦激光器的同步信号用作基本电路启动信号。 具有适当的电子定时延迟的电路产生到Nd：YAG激光器的Q开关信号，以控制放大器泵脉冲与染料激光脉冲重叠，因为它到达光放大器链的每个级。

公开(公告)号：US4540282A

公开(公告)日：1985-09-10

申请号：US477634

申请日：1983-03-21

Applicant: Isaac J. Landa ,  Ronald Shideler

Inventor： Isaac J. Landa ,  Ronald Shideler

IPC: G01J3/18 ,  G01J3/28 ,  G01J3/42

CPC classification number: G01J3/42 ,  G01J2003/2866 ,  G01J2003/421 ,  G01J3/1838 ,  G01J3/2889

Abstract: An electro-optical system for rapid, accurate spectral analysis of the reflectivity or transmissivity of samples. A concave, holographic diffraction grating is oscillated at high speed to provide a rapid scanning of monochromatic light through a spectrum of wavelengths. The grating drive system is an electrically driven mechanical oscillator which utilizes the back EMF of the oscillator motor to maintain oscillation at the desired amplitude and frequency. A passive optical shutter mounted to the grating alternately blocks the light entering and exiting the monochrometer as the grating is oscillated. The resultant dark period is utilized by the system to provide a reference offset value and to control cooling of the detectors. A unique phase-locked loop circuit is employed to provide sample commands at precisely determined intervals to correctly correlate the spectral data with the output of the monochrometer. Source and exit optics are employed to optimally shape the light passing through the system. A unique detection head is provided to allow measurement of light transmission or reflectance with only slight modification of the system. An optical fiber is used to divert light from the beam at or near the sample. This light is electronically detected and the electronic detection signal is used to adjust the gain of the sample signal so as to compensate for atmospheric bands, temporal variations, and system response. This provides a true double (dual) beam operation.

Abstract translation: 一种用于对样品的反射率或透射率进行快速，准确的光谱分析的电光系统。 凹入的全息衍射光栅以高速振荡，以提供通过一系列波长的单色光的快速扫描。 光栅驱动系统是电驱动的机械振荡器，其利用振荡器电动机的反电动势将振荡保持在期望的幅度和频率。 安装到光栅的无源光学快门在光栅振荡时交替地阻挡进入和离开单色仪的光。 所产生的暗周期被系统利用以提供参考偏移值并且控制检测器的冷却。 采用独特的锁相环电路以精确确定的间隔提供采样命令，以使光谱数据与单色仪的输出正确相关。 采用光源和出射光学器件来最佳地对穿过系统的光进行成形。 提供独特的检测头以允许仅对系统进行轻微修改来测量光透射或反射。 使用光纤来从样品中或附近的光束转移光线。 该光被电子检测，电子检测信号用于调整采样信号的增益，以补偿大气带，时间变化和系统响应。 这提供了一个真正的双（双）光束操作。

公开(公告)号：US4299488A

公开(公告)日：1981-11-10

申请号：US096686

申请日：1979-11-23

Applicant: Walter J. Tomlinson, III

Inventor： Walter J. Tomlinson, III

IPC: G01J3/28 ,  G02B6/28 ,  G02B6/34 ,  G01J3/12 ,  G01J3/18 ,  H04B9/00

CPC classification number: G02B6/2861 ,  G01J3/2889 ,  G02B6/2931

Abstract: A time-division multiplexed spectrometer (TMS) which can convert the output from a pulsed continuum radiation source into a time- and wavelength-division multiplexed pulse train is provided, by a single spectrometer (1, 2) when: (a) an input source (100) is terminated at the image plane of the spectrometer at a first position which is displaced from the symmetry plane, (b) the first end of a set of optical fibers (100-110), each having a different length, are determined at the image plane at positions which are displaced in the opposite direction from the symmetry plane as is the first position, whereby narrowband portions of the output spectrum are picked up and delayed by different amounts, (c) the second end of the set are terminated at the image plane at positions which are reflections of the terminations of the first end about the symmetry plane, whereby the signals are reinjected into the instrument and refocused onto a second position at the image plane corresponding to the reflection of the first position about the symmetry plane, and (d) an optical receptor is terminated at the second position.

Abstract translation: 通过单个光谱仪（1,2）在下列情况下提供可将脉冲连续辐射源的输出转换为时间和波分复用脉冲序列的时分多路复用谱仪（TMS）：（a）输入 源极（100）在从对称平面偏移的第一位置处终止在光谱仪的像面处，（b）一组光纤（100-110）的第一端（每个具有不同长度）是 在像平面处在与第一位置相对的方向上从对称平面位移的位置处确定，由此输出频谱的窄带部分被拾取并延迟不同的量，（c）组的第二端 在作为第一端的终端围绕对称平面的反射的位置处的位置处终止于图像平面，由此将信号重新注入到仪器中并重新聚焦到与反射镜相对应的图像平面处的第二位置 关于对称平面的第一位置的反射，和（d）光学受体在第二位置终止。