DEVICE FOR WIDE-BAND SPECTRAL ANALYSIS OF A SIGNAL OF INTEREST

    公开(公告)号:US20230417810A1

    公开(公告)日:2023-12-28

    申请号:US18039205

    申请日:2021-12-03

    CPC classification number: G01R23/165 G01J3/1256

    Abstract: A wideband device for the spectral analysis of a signal of interest includes a source designed to generate the signal of interest; an optical splitter element designed to spatially split the signal of interest into a first signal and a second signal; a first frequency-shifting optical cavity comprising a first frequency shifter designed to shift the optical frequency of the first signal by a first frequency f1 per round trip in the first cavity, the first cavity having a first trip time τ1; a second frequency-shifting optical cavity comprising a second frequency shifter designed to shift the optical frequency of the second signal by a second frequency f2 per round trip in the second cavity, the second cavity having a second trip time τ2; the first and the second optical cavity being designed such that a maximum number of round trips of the signal in the first and the second cavity is equal to predetermined N; a detector designed to coherently detect the first signal transmitted by the first cavity and the second signal transmitted by the second cavity and generate a photocurrent proportional to a luminous intensity detected by the detector, an analog low-pass filter designed to filter frequencies of the photocurrent that are lower than min (f12/; f2/2) a processor configured to compute a square modulus of the photocurrent filtered by the low-pass filter, from which a temporal representation of frequency information of the signal of interest is determined.

    SCANNING MICROSCOPE AND ACOUSTO-OPTICAL MAIN BEAM SPLITTER FOR A SCANNING MICROSCOPE
    3.
    发明申请
    SCANNING MICROSCOPE AND ACOUSTO-OPTICAL MAIN BEAM SPLITTER FOR A SCANNING MICROSCOPE 有权
    用于扫描显微镜的扫描显微镜和光学主光束分离器

    公开(公告)号:US20160223882A1

    公开(公告)日:2016-08-04

    申请号:US14916520

    申请日:2014-09-03

    Abstract: The invention relates to an acousto-optic main beam splitter for a scanning microscope, which is embodied and intended to direct illuminating light having a preselected or preselectable illuminating light wavelength into an illumination beam path for illumination of a sample, and to direct detected light coming from a sample into a detection beam path. The acousto-optic main beam splitter is characterized in that a mechanical wave having an acoustic frequency associated with the illuminating light wavelength propagates, or multiple mechanical waves that have the same acoustic frequency associated with the illuminating light wavelength propagate, in the acousto-optic main beam splitter, both a portion of the detected light bundle having the illuminating light wavelength and a first linear polarization direction, and a portion of the detected light having the illuminating light wavelength and a second linear polarization direction perpendicular to the first linear polarization direction, being deflected out of the detected light bundle coming from a sample by interaction with the one mechanical wave or by interaction with the mechanical waves, and are thereby removed from the detected light bundle; and/or the acousto-optic main beam splitter being embodied to direct, by interaction with the one mechanical wave or by interaction with the mechanical waves, both the portion of illuminating light that has the preselected illuminating light wavelength and a first linear polarization direction, and the portion of illuminating light that has the preselected illuminating light wavelength and a second linear polarization direction that is different from, in particular perpendicular to, the first linear polarization direction, into an illumination beam path for illumination of a sample.

    Abstract translation: 本发明涉及一种用于扫描显微镜的声光主分束器,其被实施并旨在将具有预选或可选择的照明光波长的照明光引导到用于照射样品的照明光束路径中,并将检测到的光引导 从样品到检测光束路径。 声光主分束器的特征在于具有与照明光波长相关联的声频的机械波传播,或者具有与照明光波长相关联的相同声频的多个机械波在声光主体中传播 检测到的光束的一部分具有照明光波长和第一线偏振方向的一部分以及具有照射光波长的检测光的一部分和与第一线偏振方向垂直的第二线偏振方向, 通过与一个机械波的相互作用或通过与机械波的相互作用而偏离来自样品的检测到的光束,从而从检测到的光束中除去; 和/或声光主分束器被实现为通过与一个机械波相互作用或通过与机械波的相互作用来引导具有预选照明光波长的照明光的一部分和第一线偏振方向, 以及将具有预选照明光波长的照明光和不同于特别是垂直于第一线偏振方向的第二线偏振方向的部分转换成用于照射样本的照明光束路径。

    Spectral estimation parameter generation device, method of generating spectral estimation parameter, and spectral estimation device
    5.
    发明授权
    Spectral estimation parameter generation device, method of generating spectral estimation parameter, and spectral estimation device 有权
    光谱估计参数产生装置,产生光谱估计参数的方法和光谱估计装置

    公开(公告)号:US08587783B2

    公开(公告)日:2013-11-19

    申请号:US13472052

    申请日:2012-05-15

    Applicant: Yoshifumi Arai

    Inventor: Yoshifumi Arai

    Abstract: A device measures a spectral distribution with respect to each of a plurality of color charts, sets default values to band specification data, and computes a camera output signal based on spectral sensitivity of the multiband camera and spectral feature of light from each of the plurality of charts. The device computes a candidate value of a spectral estimation parameter from the measured spectral distribution of each color chart and the computed camera output signal. The device successively varies the band specification data from the default values to make an evaluation function approach a target value, determines a spectral estimation parameter corresponding to the band specification data when the evaluation function reaches the target value. The evaluation function is defined to correlate the measured spectral distribution of each color chart to a spectral estimation value computed from the candidate value of the spectral estimation parameter and the camera output signal.

    Abstract translation: 设备测量相对于多个色彩图中的每一个的光谱分布,将默认值设置为频带指定数据,并且基于多频带相机的光谱灵敏度和多频带相机中的每一个的光谱特征来计算相机输出信号 图表。 该装置根据每个颜色图表的测量光谱分布和计算出的相机输出信号计算光谱估计参数的候选值。 该装置根据默认值连续地改变频带规格数据,使得评估功能达到目标值,当评估功能达到目标值时,确定与频带规格数据对应的频谱估计参数。 该评估函数被定义为将每个颜色图表的测量光谱分布与从光谱估计参数和相机输出信号的候选值计算的光谱估计值相关联。

    Noninvasive detection of elements and/or chemicals in biological matter
    6.
    发明授权
    Noninvasive detection of elements and/or chemicals in biological matter 有权
    生物物质中元素和/或化学物质的无创检测

    公开(公告)号:US08218143B2

    公开(公告)日:2012-07-10

    申请号:US12687469

    申请日:2010-01-14

    Applicant: Neelam Gupta

    Inventor: Neelam Gupta

    Abstract: A method of detecting oxygen and/or chemical content in a subject, comprising generating at least one spectral image of the subject; generating at least one spectral image of a reference object; comparing spectrum from the subject image to the reference image to thereby reveal the relative oxygen content of the subject. A system for determining the level of oxygenation of the blood of a subject body part comprising: a hyperspectral image generator for generating a plurality of spectral images; an image capture device for capturing the spectral images; a processor for generating hyperspectral image cubes such that the spectrum of the body part is extracted and normalized using the spectrum from the reference object to cancel out the spectral response of the light source and the imager; said processor comparing spectral from a subject image to reference images to thereby reveal the relative oxygen content of the subject.

    Abstract translation: 一种检测受试者中氧和/或化学含量的方法,包括产生所述受试者的至少一个光谱图像; 生成参考对象的至少一个光谱图像; 将来自对象图像的光谱与参考图像进行比较,从而显示对象的相对氧含量。 一种用于确定被摄体体部分的血液氧合水平的系统,包括:用于产生多个光谱图像的高光谱图像发生器; 用于捕获光谱图像的图像捕获装置; 用于产生高光谱图像立方体的处理器,使得使用来自参考对象的光谱提取和归一化身体部分的光谱,以抵消光源和成像器的光谱响应; 所述处理器将来自对象图像的光谱与参考图像进行比较,从而显示对象的相对氧含量。

    Method for operating an optical filter in multiple modes
    7.
    发明申请
    Method for operating an optical filter in multiple modes 有权
    用于在多种模式下操作滤光器的方法

    公开(公告)号:US20120062888A1

    公开(公告)日:2012-03-15

    申请号:US13199859

    申请日:2011-09-12

    CPC classification number: G01J3/1256 G01J3/12 G01J3/26

    Abstract: A method for operating an optical filter in multiple modes. In one embodiment, an optical filter may be operated in a sensitivity mode to thereby generate a white light image representative of a region of interest. The optical filter may then be operated in a specificity mode to thereby generate a hyperspectral image representative of said region of interest. The white light image and the hyperspectral image may be fused to generate a hybrid image that provides morphological and hyperspectral data. The white light image and the hyperspectral image may be generated using a single detector, eliminating the need for image realignment.

    Abstract translation: 一种用于以多种模式操作滤光器的方法。 在一个实施例中,可以以灵敏度模式操作滤光器,从而产生表示感兴趣区域的白光图像。 然后可以以特异性模式操作滤光器,从而产生代表所述感兴趣区域的高光谱图像。 可以融合白光图像和高光谱图像以产生提供形态和高光谱数据的混合图像。 可以使用单个检测器生成白光图像和高光谱图像,从而不需要图像重新对准。

    AOTF-based imaging system and method for hyperspectral and multispectral imaging of specimens including medical tissue
    8.
    发明授权
    AOTF-based imaging system and method for hyperspectral and multispectral imaging of specimens including medical tissue 有权
    基于AOTF的成像系统和用于包括医疗组织的标本的高光谱和多光谱成像的方法

    公开(公告)号:US08110159B2

    公开(公告)日:2012-02-07

    申请号:US12675677

    申请日:2008-09-02

    Abstract: An imaging system includes a platform for placement of a sample or an animal to be imaged, and at least one excitation light source for irradiating the sample or animal to stimulate an emission at a plurality of different center wavelengths. An acousto-optic tunable filter (AOTF) is provided that includes a piezoelectric transducer crystal for emitting an acoustic wave having a ground electrode disposed on one side of the piezoelectric crystal. A patterned electrode layer is disposed on a side of the piezoelectric crystal opposite the ground electrode. The patterned electrode layer includes a continuous region proximate to its center and a discontinuous region, a pattern in the discontinuous region comprising a plurality of spaced apart features electrically connected to the continuous region, and an AO interaction crystal receiving the acoustic wave attached to the ground electrode or the patterned electrode layer.

    Abstract translation: 成像系统包括用于放置待成像的样品或动物的平台,以及用于照射样品或动物以刺激多个不同中心波长的发射的至少一个激发光源。 提供了一种声光可调滤波器(AOTF),其包括用于发射声波的压电换能器晶体,该声波具有设置在压电晶体一侧的接地电极。 图案化电极层设置在与接地电极相对的压电晶体的一侧。 图案化电极层包括靠近其中心的连续区域和不连续区域,不连续区域中的图案包括电连接到连续区域的多个间隔的特征,以及接收附着于地面的声波的AO相互作用晶体 电极或图案化电极层。

    Imaging apparatus and light source estimating device for the imaging apparatus
    9.
    发明授权
    Imaging apparatus and light source estimating device for the imaging apparatus 有权
    用于成像装置的成像装置和光源估计装置

    公开(公告)号:US07514669B2

    公开(公告)日:2009-04-07

    申请号:US11798069

    申请日:2007-05-10

    CPC classification number: G01J3/44 G01J3/1256 G01J3/2823 G01J2003/1213

    Abstract: A light source estimating device includes: a distribution holding section holding a spectral energy distribution of a specific light source as a specular reflection component; a set generating section generating a set determined by the specular reflection component and pixel data of the input image in a predetermined space, with respect to each pixel data of the input image; a detecting section detecting, with respect to each pixel data of the input image, another pixel data neighboring the pixel data and included in the set; and a determining section determining whether or not the specific light source corresponds to the light source used during capture, by setting a likelihood that the specific light source corresponds to the light source used during capture high if the other pixel data exists, and setting a likelihood that the specific light source corresponds to the light source used during capture low if the other pixel data does not exist.

    Abstract translation: 光源估计装置包括:保持特定光源的光谱能量分布作为镜面反射分量的分布保持部; 相对于输入图像的每个像素数据产生由预测空间中的输入图像的镜面反射分量和像素数据确定的集合的集合生成部分; 检测部,相对于所述输入图像的每个像素数据检测与所述集合中包含的像素数据相邻的另一像素数据; 以及确定部分,通过将特定光源对应于捕获期间使用的光源的可能性设置为高,如果存在其他像素数据,则确定特定光源是否对应于捕获期间使用的光源,并且设置似然 如果其他像素数据不存在,则特定光源对应于捕获期间使用的光源低。

    OPTICAL SPECTRUM ANALYZER
    10.
    发明申请
    OPTICAL SPECTRUM ANALYZER 有权
    光谱分析仪

    公开(公告)号:US20080259332A1

    公开(公告)日:2008-10-23

    申请号:US12165721

    申请日:2008-07-01

    CPC classification number: G01J3/1256 G01J3/02 G01J3/0256 G01J9/0246 G01J9/04

    Abstract: An optical spectrum analyzer detects a light output that is dependent on the frequency of light in a wavelength range of light to be measured. The optical spectrum analyzer includes a waveguide acousto-optic tunable filter including a piezoelectric substrate, optical waveguides, and an IDT, a light source for providing, to the waveguide acousto-optic tunable filter, reference light having a particular wavelength outside the wavelength range, a driving circuit for providing, to the waveguide acousto-optic tunable filter, a high frequency signal for exciting an IDT, and an arithmetic device that, on the basis of the wavelength of selected light when reference light is incident, and an exciting frequency, corrects the wavelength of the selected light, which is obtained from the light to be measured.

    Abstract translation: 光谱分析仪检测取决于待测光的波长范围内的光的频率的光输出。 光谱分析仪包括波导声光可调谐滤波器,其包括压电基片,光波导和IDT,用于向波导声光可调谐滤波器提供在波长范围外具有特定波长的参考光的光源, 用于向波导声光可调滤波器提供用于激励IDT的高频信号的驱动电路,以及基于参考光入射时所选择的光的波长和激励频率的运算器件, 校正从被测光获得的所选择的光的波长。

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