公开(公告)号：US06535284B1

公开(公告)日：2003-03-18

申请号：US09579338

申请日：2000-05-25

Applicant: Damian Hajduk ,  Eric Carlson

Inventor： Damian Hajduk ,  Eric Carlson

IPC: G01J400

CPC classification number: G01N21/21 ,  B01J2219/00286 ,  B01J2219/00315 ,  B01J2219/00585 ,  B01J2219/00659 ,  B01J2219/00707 ,  B01J2219/0072 ,  B01J2219/00745 ,  C40B40/18 ,  C40B60/14 ,  G01J4/04 ,  G01N2201/0813

Abstract: A method and apparatus for characterizing and screening an array of material samples is disclosed. The apparatus includes a sample block having a plurality of regions for containing the material samples, a polarized light source to illuminate the materials, an analyzer having a polarization direction different than the polarization direction of the polarized light source, and a detector for analyzing changes in the intensity of the light beams. The light source, together with a polarizer, may include a plurality of light beams to simultaneously illuminate the entire array of materials with linearly polarized light so that characterization and screening can be performed in parallel. In addition, the materials in the sample block maybe subjected to different environmental conditions or mechanical stresses, and the detector analyzes the array as a function of the different environmental conditions or mechanical stresses.

Abstract translation: 公开了一种表征和筛选材料样品阵列的方法和装置。 该装置包括具有用于容纳材料样本的多个区域的样本块，用于照射材料的偏振光源，具有与偏振光源的偏振方向不同的偏振方向的分析器，以及用于分析变化的检测器 光束的强度。 光源与偏振器一起可以包括多个光束，以同时以线性偏振光照射整个材料阵列，从而可以并行执行表征和筛选。 此外，样品块中的材料可能经受不同的环境条件或机械应力，并且检测器根据不同的环境条件或机械应力来分析阵列。

公开(公告)号：US6108083A

公开(公告)日：2000-08-22

申请号：US907903

申请日：1997-08-11

Applicant: Meinrad Machler

Inventor： Meinrad Machler

IPC: G01J3/02 ,  G01N21/03 ,  G01N21/27 ,  G01N21/55 ,  G01J3/18 ,  G01N21/05

CPC classification number: G01N21/0303 ,  G01J3/02 ,  G01J3/0216 ,  G01N2201/0813 ,  G01N2201/084

Abstract: A spectroscopic system for the analysis of small quantities of substances makes use for the purposes of energy transfer of cone-shaped aperture changers which are arranged in the object zone between the light source and the sample and, during absorption measurements, also between the sample and the inlet slot of a spectrometer. A microcell system is provided in the object space. The microcell system comprises a cylindrical cell tube with a hollow core for receiving a sample liquid. The cell tube and the sample liquid being adjustable with respect to the refractive index such that they act as a step waveguide for radiation, the sample liquid forming the core and the wall of the cell tube forming the sheath of the step waveguide.

Abstract translation: 用于分析少量物质的光谱系统用于锥形孔径变换器的能量转移的目的，锥形孔径变换器布置在光源和样品之间的物体区域中，并且在吸收测量期间也用于样品和 光谱仪的入口槽。 在对象空间中提供微小区系统。 微电池系统包括具有用于接收样品液体的中空芯的圆柱形电池管。 细胞管和样品液体相对于折射率可调节，使得它们用作辐射的步进波导，形成芯的样品液体和形成步进波导的护套的细胞管的壁。

公开(公告)号：US5680209A

公开(公告)日：1997-10-21

申请号：US381911

申请日：1995-05-02

Applicant: Meinrad Machler

Inventor： Meinrad Machler

IPC: G01J3/02 ,  G01N21/03 ,  G01N21/27 ,  G01N21/55 ,  G01J3/42 ,  G01J3/447

CPC classification number: G01N21/0303 ,  G01J3/02 ,  G01J3/0216 ,  G01N2201/0813 ,  G01N2201/084

Abstract: A spectroscopic system for the analysis of small and very small quantities of substances makes use for the purposes of energy transfer of cone-shaped aperture changers (14, 15) which are arranged in the object zone (8) between the light source (L) and the sample (9) and, during absorption measurements, also between the sample (9) and the inlet slot (3) of a spectrometer (1). If the form used is a double cone, the aperture changers (14, 15) facilitate an oblique coupling in a capillary tube accepting the sample (9) which acts as a step-waveguide for the coupled radiation.

Abstract translation: PCT No.PCT / EP93 / 02166 Sec。 371日期：1995年5月2日 102（e）日期1995年5月2日PCT提交1993年8月13日PCT公布。 出版物WO94 / 04892 日期1994年3月3日用于分析小量和非常少量物质的光谱系统用于锥形孔径变换器（14,15）的能量传递的目的，锥形孔径变换器（14,15）布置在物体区域（8）之间 光源（L）和样品（9），并且在吸收测量期间也在样品（9）和光谱仪（1）的入口槽（3）之间。 如果使用的形式是双锥形，则孔径更换器（14,15）有助于在接受用作耦合辐射的阶跃波导的样品（9）的毛细管中的倾斜耦合。

公开(公告)号：US5155628A

公开(公告)日：1992-10-13

申请号：US382296

申请日：1989-07-20

Applicant: Andrew J. Dosmann

Inventor： Andrew J. Dosmann

IPC: G01N21/25 ,  G02B27/12

CPC classification number: G02B27/108 ,  G01N21/255 ,  G02B27/1006 ,  G02B27/143 ,  G02B27/144 ,  G01N2021/1742 ,  G01N2201/0813

Abstract: An optical transmission spectrometer for transmission measurements of absorbing and scattering samples includes light sources mounted parallel to each other in a holder. The beams of light emanating from the light sources are directed through a beam-combiner. The beam-combiner includes a first refractive surface at an angle of incidence of 45.degree.. The first refractive surface refracts light toward a common axis. The beam-combiner includes a second refractive surface parallel to the first refractive surface for refracting the beam of light along a common axis parallel to the original direction of the beam of light. The beam-combiner can include additional refractive surfaces for other beams of light to combine the beams of light into a primary beam. The spectrometer includes a collimating tube extending along the common axis for baffling stray light and directing the primary beam through a sample. A second collimating tube is provided on the side of the sample opposite the first collimating tube for baffling stray light passing through the sample. The second collimating tube directs the primary beam to a detector package mounted in a holder, where the detector viewing area of the sample is limited to that of the primary beam. As an alternative, an optic which is capable of directing multiple light beams onto a common intersection point may be used in place of the previously mentioned beam-combiner. Unlike the beam-combiner which closely aligns multiple parallel light beams and transmits them as substantially a single beam along the common axis, the alternate optical directs multiple light beams at an angle onto a common intersection point. The optic is fabricated from translucent material with first and second refractive surfaces for receiving light beams from a source and refracting the light beams toward the common intersection point.

Abstract translation: 用于吸收和散射样品的透射测量的光学透射光谱仪包括在保持器中彼此平行地安装的光源。 从光源发出的光束被引导通过光束组合器。 光束组合器包括45°入射角的第一折射表面。 第一折射表面朝向公共轴线折射光。 光束组合器包括平行于第一折射表面的第二折射表面，用于沿着平行于光束的原始方向的公共轴折射光束。 光束组合器可以包括用于其他光束的附加折射表面，以将光束组合成主光束。 光谱仪包括沿公共轴延伸的准直管，用于挡板杂散光并将主光束引导通过样品。 第二准直管设置在与第一准直管相对的样品的侧面上，用于挡住通过样品的杂散光。 第二准直管将主光束引导到安装在保持器中的检测器封装，其中样品的检测器观察面积被限制为主光束的检测器观看面积。 作为替代，可以使用能够将多个光束引导到公共交叉点上的光学器件来代替先前提到的光束组合器。 与将多个平行光束紧密对准并将其作为基本上沿着公共轴线的单个光束传输的光束组合器不同，备选光学器件将多个光束以一定角度引导到公共交叉点上。 光学元件由具有第一和第二折射表面的半透明材料制成，用于接收来自源的光束并将光束折射到公共交叉点。

公开(公告)号：US4368980A

公开(公告)日：1983-01-18

申请号：US162257

申请日：1980-06-23

Applicant: Phillip J. E. Aldred ,  Peter J. Taylor ,  Bryan W. Kenzie

Inventor： Phillip J. E. Aldred ,  Peter J. Taylor ,  Bryan W. Kenzie

IPC: G01N21/35 ,  G01N21/31 ,  G01V8/10 ,  G01N21/90 ,  B07C5/342

CPC classification number: G01N21/3554 ,  G01N21/314 ,  G01N2201/0813

Abstract: The invention relates to apparatus for detecting water-based residues in translucent bottles, in which energy in two parts of the spectrum in and near the infra-red region, in one of which parts (0.8 to 0.9 microns) water is relatively transparent and the other of which parts (1.2 to 1.6 microns) water is more strongly absorbent is transmitted through a bottle, and the intensities of the emergent energies in the two parts are separately measured by a silicon detector and a germanium detector, associated with respective collimator tubes and filters, and are compared to produce a signal indicative of the presence of water in the bottle.

Abstract translation: 本发明涉及用于检测半透明瓶中的水基残留物的设备，其中红外区域内和附近的光谱的两部分中的能量在其中一个部分（0.8至0.9微米）的水中相对透明， 另一部分（1.2至1.6微米）的水更强吸收性透过瓶子，两部分的出射能的强度分别通过与各准直仪管相关联的硅检测器和锗检测器测量， 过滤器，并进行比较以产生指示瓶中存在水的信号。

公开(公告)号：US3536409A

公开(公告)日：1970-10-27

申请号：US3536409D

申请日：1968-02-21

Applicant: US AGRICULTURE

Inventor： BELSER RICHARD B ,  MEADERS JAMES C ,  KWON CHIN T

IPC: D06H3/08 ,  G01N21/898 ,  G01N21/32

CPC classification number: G01N21/8983 ,  D06H3/08 ,  G01N2201/0813

公开(公告)号：US3509341A

公开(公告)日：1970-04-28

申请号：US3509341D

申请日：1966-06-01

Applicant: PICKER CORP

Inventor： HINDEL ROBERT ,  UTTING GEORGE R

IPC: G01T1/164 ,  G01T1/166 ,  G01T1/29 ,  G01T1/20

CPC classification number: G01T1/1644 ,  A61B6/4258 ,  G01N2201/0813 ,  G01T1/166 ,  G01T1/2978

公开(公告)号：US3435240A

公开(公告)日：1969-03-25

申请号：US3435240D

申请日：1964-01-02

Applicant: INDUSTRIAL NUCLEONICS CORP

Inventor： BRUNTON DONALD C

IPC: G01N21/47 ,  G01N21/86 ,  G01N21/30 ,  G01L5/04

CPC classification number: G01N21/86 ,  G01N21/47 ,  G01N2201/0813

公开(公告)号：US07738945B2

公开(公告)日：2010-06-15

申请号：US10716744

申请日：2003-11-18

Applicant: Mark E. Fauver ,  J. Richard Rahn ,  Eric J. Seibel ,  Alan C. Nelson

Inventor： Mark E. Fauver ,  J. Richard Rahn ,  Eric J. Seibel ,  Alan C. Nelson

IPC: A61B5/05

CPC classification number: G01N15/1475 ,  G01N15/1468 ,  G01N15/147 ,  G01N21/05 ,  G01N21/4795 ,  G01N2015/1006 ,  G01N2015/1075 ,  G01N2015/1447 ,  G01N2021/0346 ,  G01N2021/1787 ,  G01N2201/0813 ,  G01N2223/612 ,  G06T11/006 ,  G06T2211/421

Abstract: A system for optical imaging of a thick specimen that permits rapid acquisition of data necessary for tomographic reconstruction of the three-dimensional (3D) image. One method involves the scanning of the focal plane of an imaging system and integrating the range of focal planes onto a detector. The focal plane of an optical imaging system is scanned along the axis perpendicular to said plane through the thickness of a specimen during a single detector exposure. Secondly, methods for reducing light scatter when using illumination point sources are presented. Both approaches yield shadowgrams. This process is repeated from multiple perspectives, either in series using a single illumination/detection subsystem, or in parallel using several illumination/detection subsystems. A set of pseudo-projections is generated, which are input to a three dimensional tomographic image reconstruction algorithm.

Abstract translation: 一种用于光学成像厚样本的系统，其允许快速获取三维（3D）图像的层析成像重建所需的数据。 一种方法涉及扫描成像系统的焦平面并将焦平面的范围集成到检测器上。 在单个检测器曝光期间，光学成像系统的焦平面沿着垂直于所述平面的轴线扫描样本的厚度。 其次，提出了使用照明点源时减少光散射的方法。 两种方法产生阴影图。 该过程从多个角度重复，使用单个照明/检测子系统串联使用，或者使用几个照明/检测子系统并行重复。 生成一组伪投影，其被输入到三维断层图像重建算法。

公开(公告)号：US20060061759A1

公开(公告)日：2006-03-23

申请号：US11225044

申请日：2005-09-14

Applicant: Shigeki Matsumoto ,  Shigenori Nozawa

Inventor： Shigeki Matsumoto ,  Shigenori Nozawa

IPC: G01N21/01

CPC classification number: G01N21/0303 ,  B01L3/502715 ,  B01L9/527 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/0867 ,  G01N2201/0813

Abstract: A unit for measurement of absorbance using a microchip has a microchip with a continuous cavity, a sample chamber, a reagent chamber, a reagent mixing chamber and a chamber for measuring absorbance, which is arranged in a straight line in the area of the continuous cavity. The microchip is located in a chip holder which has a capillary part which is arranged such that the light used to measure absorbance is delivered through the capillary part to the chamber for measuring absorbance, the capillary part having a smaller opening diameter than the diameter of the cross section which is perpendicular to the optical axis of the chamber for measuring absorbance.

Abstract translation: 使用微芯片测量吸光度的单元具有连续空腔的微芯片，样品室，试剂室，试剂混合室和用于测量吸光度的室，其在连续空腔的区域中以直线布置 。 微芯片位于具有毛细管部分的芯片保持器中，该毛细管部分布置成使得用于测量吸光度的光通过毛细管部分传送到用于测量吸光度的腔室，毛细管部分的开口直径小于 横截面垂直于室的光轴测量吸光度。