Detection of biotargets using bioreceptor functionalized nanoparticles
    41.
    发明授权
    Detection of biotargets using bioreceptor functionalized nanoparticles 失效
    使用生物受体功能化纳米粒子检测生物靶

    公开(公告)号:US08026108B1

    公开(公告)日:2011-09-27

    申请号:US11875252

    申请日:2007-10-19

    CPC分类号: G01N33/54346

    摘要: An ultra sensitive method for detection of biomolecules includes the step of providing a plurality of bioreceptor functionalized nanoparticle probes. The nanoparticles can include metal, semiconductor, radioactive isotope or fluorescent dye molecules. A sample solution suspected of including the target is contacted with the probes, wherein if present, the target binds to the bioreceptor. After such binding a separating step follows. In the separating step, probes having the target bound thereto are separated from probes not having the target bound thereto. In one embodiment probes having the target bound thereto are then decomposed to generate ions, or broken into discrete radioactive isotopes or fluorescent dye molecules to form a solution including a large plurality of metal ions, radioactive isotopes or dye molecules. A concentration of ions, radioactive isotopes, or dye molecules in the solution is then determined and using this information the concentration of the target in the original sample solution is determined.

    摘要翻译: 用于检测生物分子的超灵敏方法包括提供多个生物受体官能化纳米颗粒探针的步骤。 纳米颗粒可以包括金属,半导体,放射性同位素或荧光染料分子。 将涉及包含目标物的样品溶液与探针接触,如果存在,则靶标与生物受体结合。 在这种结合之后,分离步骤如下。 在分离步骤中,将与其结合的靶的探针从不具有与其结合的靶的探针分离。 在一个实施方案中,将与其结合的靶标的探针然后分解产生离子,或者分解成离散的放射性同位素或荧光染料分子,以形成包含大量金属离子,放射性同位素或染料分子的溶液。 然后确定溶液中离子,放射性同位素或染料分子的浓度,并使用该信息确定原始样品溶液中靶的浓度。

    Noninvasive glucose monitor
    42.
    发明授权
    Noninvasive glucose monitor 有权
    无创血糖监测仪

    公开(公告)号:US07972862B2

    公开(公告)日:2011-07-05

    申请号:US11843247

    申请日:2007-08-22

    IPC分类号: G01N33/00

    摘要: A method of sensing glucose in subjects includes the steps of providing a sensing solution including a plurality of metal ions, introducing a bodily fluid sample from a subject into the sensing solution. An optically-based measurable derived from directing incident light on the solution is generated. The concentration of glucose in the bodily fluid using the measurable is then determined which permits the blood glucose level to be derived.

    摘要翻译: 感测受试者中的葡萄糖的方法包括以下步骤:提供包括多个金属离子的感测溶液,将来自受试者的体液样品引入感测溶液中。 产生了将入射光引导到溶液上的基于光学的可测量的。 然后确定使用可测量的体液中的葡萄糖浓度,其允许导出血糖水平。

    System, method and algorithm for data-driven equipment performance monitoring
    43.
    发明授权
    System, method and algorithm for data-driven equipment performance monitoring 有权
    用于数据驱动设备性能监控的系统,方法和算法

    公开(公告)号:US07966152B2

    公开(公告)日:2011-06-21

    申请号:US12108076

    申请日:2008-04-23

    CPC分类号: G05B23/0232

    摘要: A method for automatically monitoring the performance of equipment includes compiling current operating conditions associated with current conditions (PMc). A historical database including a plurality of stored operating conditions and associated stored performance measure (PM*) is searched, each stored operating condition including at least one stored sensor reading, wherein at least one similar operating condition is identified in the search using distances between the current operating conditions and the stored operating conditions. The performance measure (PM*) associated with the similar operating condition is fit to generate a regression model. The regression model is applied to the current operating condition to generate an estimate for the performance measure for the current operating condition (PMe). A difference between PMc and PMe is computed. The first difference is compared to a predetermined threshold, wherein a warning is automatically generated if the first difference has a value greater than the predetermined threshold.

    摘要翻译: 用于自动监测设备性能的方法包括编译与当前条件(PMc)相关的当前操作条件。 搜索包括多个存储的操作条件和相关联的存储性能测量(PM *)的历史数据库,每个存储的操作条件包括至少一个存储的传感器读数,其中在搜索中识别至少一个相似的操作条件, 当前操作条件和存储的操作条件。 与类似操作条件相关的性能指标(PM *)适合于生成回归模型。 将回归模型应用于当前运行状况,以生成针对当前运行状况(PMe)的性能测量的估计。 计算PMc和PMe之间的差异。 将第一差异与预定阈值进行比较,其中如果第一差异具有大于预定阈值的值,则自动生成警告。

    Polymer composites having highly dispersed carbon nanotubes and methods for forming same
    44.
    发明授权
    Polymer composites having highly dispersed carbon nanotubes and methods for forming same 失效
    具有高度分散的碳纳米管的聚合物复合材料及其形成方法

    公开(公告)号:US07951850B2

    公开(公告)日:2011-05-31

    申请号:US12050780

    申请日:2008-03-18

    IPC分类号: B60C1/00 C08K3/04

    摘要: A method of forming carbon nanotube-polymer composites includes the steps of forming a mixture solution including a plurality of carbon nanotubes dispersed in a co-solvent. The co-solvent includes an organic solvent and a second solvent being a short chain fluorinated carboxylic acid having a boiling point below 150° C. which is less oxidizing than nitric acid, and is soluble in both the organic solvent and water. The first polymer is mixed with the mixture solution to form a polymer including mixture. The co-solvent is removed from the polymer mixture to form a dispersed nanotube-polymer composite. The second solvent can be trifluoroacetic acid.

    摘要翻译: 形成碳纳米管 - 聚合物复合材料的方法包括形成包含分散在共溶剂中的多个碳纳米管的混合溶液的步骤。 共溶剂包括有机溶剂,第二溶剂是沸点低于150℃的短链氟化羧酸,其比硝酸氧化性低,并且可溶于有机溶剂和水。 将第一聚合物与混合溶液混合以形成包含混合物的聚合物。 从聚合物混合物中除去共溶剂以形成分散的纳米管 - 聚合物复合材料。 第二溶剂可以是三氟乙酸。

    High light extraction efficiency solid state light sources
    45.
    发明授权
    High light extraction efficiency solid state light sources 有权
    高光提取效率固态光源

    公开(公告)号:US07932534B2

    公开(公告)日:2011-04-26

    申请号:US12797330

    申请日:2010-06-09

    IPC分类号: H01L33/00

    摘要: A solid state light source includes a substrate having a top surface and a bottom surface, and at least one optically active layer on the top surface of the substrate. At least one of the top surface, the bottom surface, the optically active layer or an emission surface on the optically active layer includes a patterned surface that includes a plurality of tilted surface features that have a high elevation portion and a low elevation portion that define a height (h), and wherein the plurality of tilted surface features define a minimum lateral dimension (r). The plurality of tilted surface features provide at least one surface portion that has a surface tilt angle from 3 to 85 degrees. The patterned surface has a surface roughness

    摘要翻译: 固态光源包括具有顶表面和底表面的衬底,以及在衬底顶表面上的至少一个光学活性层。 顶表面,底表面,光学活性层或光学活性层上的发射表面中的至少一个包括图案化表面,其包括多个倾斜表面特征,其具有高仰角部分和限定 高度(h),并且其中所述多个倾斜表面特征限定最小横向尺寸(r)。 多个倾斜表面特征提供具有3至85度的表面倾斜角度的至少一个表面部分。 图案化表面的表面粗糙度<10nm rms,h /r≥0.05。

    Ultrasonic flow meter with lens combination

    公开(公告)号:US11137275B2

    公开(公告)日:2021-10-05

    申请号:US16589466

    申请日:2019-10-01

    发明人: Bin Sai Dong Luo

    IPC分类号: G01F1/66

    摘要: An ultrasonic flow meter includes a housing for attaching to a fluid pipe. A first piezoelectric element coupled to a transmitter and receiver is configured to emit ultrasonic waves in an axial direction perpendicular to a horizontal plane defined by the piezoelectric element. A lens combination is in a lower housing portion positioned radially outside the first piezoelectric element including a refocusing lens that is ring-shaped configured for redirecting received radial ultrasonic waves to travel in an axial direction perpendicular to the horizontal plane and has a thickness profile configured to act as a matching layer for reducing multiple reflections within the lower housing portion. A second lens that is disc-shaped below the refocusing lens is configured for redirecting the radial ultrasonic waves to travel in the axial direction.

    Bulk acoustic wave (BAW) sensors for liquid level measurements

    公开(公告)号:US10168198B2

    公开(公告)日:2019-01-01

    申请号:US14577487

    申请日:2014-12-19

    摘要: A method for sensing at least one level parameter of at least one liquid in a tank. At least one bulk acoustic wave (BAW) sensor is positioned inside the tank. Electrodes of the BAW sensor are at least switchably connected to a positive feedback loop across an amplifier to provide an electronic oscillator. At least one acoustic viscosity measurement is determined from an output of the electronic oscillator, wherein the output of the electronic oscillator is different when the BAW sensor contacts the liquid as compared to when the BAW sensor contacts air. The level parameter is determined from the acoustic viscosity measurement.