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138 条记录 (耗时 0.023 秒)

    Primary human hepatocytes for native hepatitis C virus (HCV) replication
    41.
    发明申请
    Primary human hepatocytes for native hepatitis C virus (HCV) replication 审中-公开
    原生人肝细胞用于天然丙型肝炎病毒（HCV）复制

    公开(公告)号：US20060183111A1

    公开(公告)日：2006-08-17

    申请号：US11334392

    申请日：2006-01-19

    申请人： Ajit Kumar ,  Krishna Banaudha

    发明人： Ajit Kumar ,  Krishna Banaudha

    IPC分类号： C12Q1/70 ,  C12N5/08

    CPC分类号： C12N7/00 ,  C12N2770/24251

    摘要： Novel methods are disclosed for the long-term culture of human primary hepatocytes in tissue culture system. This culture system supports the replication, gene expression and dissemination of a multitude of pathogenic agents that reside in, or pass through, the liver. Among these, the invention advantageously provides for efficient hepatitis C virus (HCV) replication, and dissemination. Additionally disclosed are methods for the determining cellular receptors, hepatocyte cell subtypes, and host cell molecules required for efficient hepatic pathogen replication, expression and dissemination.

    摘要翻译： 公开了组织培养系统中人原代肝细胞长期培养的新方法。 该培养系统支持多种病原体的复制，基因表达和传播，其存在于肝脏或通过肝脏。 其中，本发明有利地提供有效的丙型肝炎病毒（HCV）复制和传播。 另外公开了确定有效的肝病原体复制，表达和传播所需的细胞受体，肝细胞细胞亚型和宿主细胞分子的方法。

    Secure multi-application card system
    47.
    发明授权
    Secure multi-application card system 失效
    安全多应用卡系统

    公开(公告)号：US06494367B1

    公开(公告)日：2002-12-17

    申请号：US09678918

    申请日：2000-10-04

    申请人： Ajit Kumar Zacharias

    发明人： Ajit Kumar Zacharias

    IPC分类号： G06K500

    CPC分类号： G07F7/1008 ,  G06Q20/04 ,  G06Q20/28 ,  G06Q20/341 ,  G06Q20/342 ,  G06Q20/3576 ,  G06Q40/025 ,  G07F7/025

    摘要： A multi-application card for providing secure access to multiple card accounts. This system includes a multi-application card storing a readable identification number corresponding to the card, and a database located remotely from the card. The database correlates the identification number with a record associated with the card, and the record contains a list of card account numbers and associated indexes. The system also includes a translator that receives a transaction request including the identification number read from the multi-application card and one of the associated indexes obtained from a source other than the card. The translator then uses the received identification number to access the corresponding record in the database, and uses the received index number to retrieve the corresponding card account number and expiry date. The translator then transmits the card account number and expiry date in response to the transaction request. With this system, a cardholder can carry a single multi-application card that provides access to multiple accounts associated with different cards by using a simple index. Thus, the cardholder can use multiple credit, debit and other non-encoded, magnetically encoded, bar-coded and microprocessor based cards, without having to carry each individual card.

    摘要翻译： 用于提供对多个卡帐户的安全访问的多应用卡。 该系统包括存储对应于该卡的可读标识号的多应用卡和远离卡的数据库。 该数据库将识别号与与该卡相关联的记录相关联，并且记录包含卡帐号和相关索引的列表。 系统还包括翻译器，其接收包括从多应用卡读取的识别号的交易请求以及从该卡之外的源获得的相关索引之一。 翻译者然后使用接收到的标识号来访问数据库中的相应记录，并使用接收到的索引号来检索相应的卡号和到期日。 翻译者然后响应于交易请求发送卡帐号和到期日。 使用该系统，持卡人可以携带单个多应用卡，通过使用简单的索引提供对与不同卡相关联的多个帐户的访问。 因此，持卡人可以使用多个信用卡，借记和其他未编码，磁编码，条形码和基于微处理器的卡，而不必携带每个单独的卡。

    Method and apparatus for providing a conductive, amorphous non-stick coating
    49.
    发明授权
    Method and apparatus for providing a conductive, amorphous non-stick coating 失效

    公开(公告)号：US06270831B1

    公开(公告)日：2001-08-07

    申请号：US09071371

    申请日：1998-04-30

    申请人： B. Ajit Kumar ,  Pratap Khanwilkar ,  Don B. Olsen

    发明人： B. Ajit Kumar ,  Pratap Khanwilkar ,  Don B. Olsen

    IPC分类号： A61L1300

    摘要： A conductive, non-stick coating is provided using a ceramic material which is conductive, flexible and provides a surface which exhibits the property of lubricity. A room or near room temperature manufacturing process produces a coating of titanium nitride on a substrate, where the coating is amorphous if the substrate is a solid material including plastics, composites, metals, magnets, and ceramics, enabling the substrate to bend without damaging the coating. The coating can also be applied as a conformal coating on a variety of substrate shapes, depending upon the application. The coating is bio-compatible and can be applied to a variety of medical devices.