摘要:
The invention relates to compounds of the formula I in which the radicals have the meanings stated in the text, their stereoisomeric forms, and their physiologically tolerated salts, physiologically functional derivatives and process for their preparation. The compounds are suitable for the treatment of disorders of metabolism, such as type 2 diabetes.
摘要:
A solenoid valve achieves high reliability and small size with fine tolerance. The solenoid valve having a valve housing, an electromagnet composed of a coil, a yoke and a clapper armature having at least a first valve seat, and a sealing element which can be actuated by the clapper armature and which co-operates with the first valve seat. The yoke has yoke pins and the clapper armature is magnetically and pivotally connecting with one of the yoke pins at the end thereof that is remote from the sealing element. The clapper armature is guided through the coil.
摘要:
1-Methyl-5-alkylsulfonyl-, 1-methyl-5-alkylsulfinyl- and 1-methyl-5-alkylthio-substituted pyrazolylpyrazoles, processes for their preparation and their use as herbicides 1 -Methyl-5-alkylsulfonyl-, 1-methyl-5-alkylsulfinyl- and 1-methyl-alkylthio-substituted pyrazolylpyrazoles of the formula (I) are described as herbicidally active compounds. In this formula (I), R1 and R4 are various substituents, R2 is halogen or cyano, R3 is cyano, nitro or thiocarbamoyl and n is 0, 1 or 2.
摘要:
The present invention relates to compounds of general formula I, wherein the group R1, R2, X and Y are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the AMP-activated protein kinase (AMPK) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.
摘要:
Heteroaryloxy-substituted benzoic acid amides of general formula I wherein the groups R1 to R7 as well as X and Y are defined according to claim 1, including the tautomers, the stereoisomers, the mixtures and the salts thereof. The compounds according to the invention are suitable for the treatment of respiratory complaints, particularly COPD and asthma.
摘要:
The invention relates to substituted arylsulphonylaminomethylphosphonic acid derivatives of general formula (I) wherein the groups Ra to Rf, A and Z are defined as mentioned in the specification and claims, which are suitable for preparing a medicament for the treatment of metabolic disorders, particularly type 1 or type 2 diabetes mellitus.
摘要:
The present invention relates to substituted arylsulphonylglycines of general formula (I) wherein R, X, Y and Z are defined as in claim 1, the tautomers, enantiomers, diastereomers, mixtures thereof and salts thereof, which have valuable pharmacological properties, particularly the suppression of the interaction of glycogen phosphorylase a with the GL subunit of glycogen-associated protein phosphatase 1 (PP1), and their use as pharmaceutical compositions.
摘要:
The present invention relates to substituted arylsulphonylglycines of general formula wherein R, R4, X, Y, Z and m are defined as in claim 1, the tautomers, enantiomers, diastereomers, mixtures thereof and salts thereof, which have valuable pharmacological properties, particularly the suppression of the interaction of glycogen phosphorylase a with the GL subunit of glycogen-associated protein phosphatase 1 (PP1), and their use as pharmaceutical compositions.
摘要:
A method for drying laundry in a laundry dryer having a program control device, a drying chamber and a process air circuit includes providing a flow dividing device in the process air circuit for dividing the drying air flow into an exhaust air component and a recirculated air component. A sensor is used to measure a pressure in the process air stream in an area where the drying air enters the drying chamber. The pressure is evaluated and the flow dividing device is controlled based on the evaluation so as to reduce or set to zero the recirculated air component and to continue the drying process at a reduced volumetric flow rate of the drying air through the drying chamber.
摘要:
The invention relates to compounds of the formula I in which the radicals have the stated meanings, their stereoisomeric forms and their physiologically tolerated salts and process for their preparation. The compounds are suitable for the treatment of metabohlic disorders such as type 2 diabetes.