公开(公告)号：US11006655B2

公开(公告)日：2021-05-18

申请号：US16321070

申请日：2016-07-29

Applicant: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION ,  MEAT & LIVESTOCK AUSTRALIA LIMITED ,  JAMES COOK UNIVERSITY

Inventor： Nigel William Tomkins ,  Rocky De Nys ,  Robert Douglas Kinley ,  Marie Elisabeth Magnusson ,  Lorenna Machado ,  Nicholas Andrew Paul

IPC: A23K10/30 ,  A23K40/20 ,  A23K50/10 ,  A23K10/16 ,  A23K40/10 ,  A23K20/20 ,  A23K20/24 ,  A61K36/02

Abstract: The invention relates to utilising red marine macroalgae to provide improvements in growth performance of livestock, particularly ruminant animals for red meat production, especially cattle, in pasture and feedlot farming systems. There is provided a method for improving the growth performance of a livestock animal in a farming system including: providing a red marine macroalgae to a farming system to enable consumption of the red marine macroalgae by a livestock animal in the farming system; thereby improving the growth performance of the livestock animal in the system.

公开(公告)号：US10881697B2

公开(公告)日：2021-01-05

申请号：US15991546

申请日：2018-05-29

Applicant: Commonwealth Scientific and Industrial Research Organisation ,  Meat & Livestock Australia Limited ,  James Cook University

Inventor： Lorenna Machado ,  Marie Elisabeth Magnusson ,  Nigel William Tomkins ,  Robert Douglas Kinley ,  Peter Canisius Denys ,  Nicholas Andrew Paul

IPC: A61K36/04 ,  A61K9/00 ,  A23K50/10 ,  A23K10/30 ,  A61P1/00

Abstract: The present invention relates to a method of reducing total gas production and/or methane production in a ruminant animal.

公开(公告)号：US20130063351A1

公开(公告)日：2013-03-14

申请号：US13232228

申请日：2011-09-14

Applicant: Raghuram Reddy Talasani ,  Stephen James Cook

Inventor： Raghuram Reddy Talasani ,  Stephen James Cook

IPC: G09G5/08

CPC classification number: G06F3/03543 ,  G06F3/039 ,  G06F2203/0332

Abstract: A computer mouse designed to reduce the symptoms of and/or prevent Carpel Tunnel Syndrome.

Abstract translation: 设计用于减少心皮管隧道综合征症状和/或预防的电脑鼠标。

公开(公告)号：US08294881B2

公开(公告)日：2012-10-23

申请号：US12198678

申请日：2008-08-26

Applicant: Dean R. Hellickson ,  Kurt Holmquist ,  James Cook ,  Andrew W. Guyette ,  Robert Burns

Inventor： Dean R. Hellickson ,  Kurt Holmquist ,  James Cook ,  Andrew W. Guyette ,  Robert Burns

IPC: G01C3/08

CPC classification number: G01S17/023 ,  G01S7/4802 ,  G01S17/42 ,  G01S17/89 ,  G01S19/13 ,  G08B13/181 ,  G08B13/19645

Abstract: A security sensor system comprises one or more laser detection and ranging (LADAR) sensors configured for accumulation of three-dimensional image data. In one embodiment, the one or more LADAR sensors each comprise a LADAR device, such as a MEMS device, configured to transmit a plurality of laser pulses, and a microprocessor operatively coupled to the LADAR device. One or more data storage devices is operatively coupled to the microprocessor and configured to store the three-dimensional image data, as well as predetermined protected area boundary and fixed object definitions. A GPS receiver can be operatively coupled to the microprocessor and a GPS antenna. The microprocessor is configured to perform a LADAR image analysis that compares the three-dimensional image data with the protected area boundary and fixed object definitions to identify one or more potential intruders.

Abstract translation: 安全传感器系统包括被配置用于累积三维图像数据的一个或多个激光检测和测距（LADAR）传感器。 在一个实施例中，一个或多个LADAR传感器各自包括被配置为传输多个激光脉冲的LADAR装置，诸如MEMS装置，以及可操作地耦合到LADAR装置的微处理器。 一个或多个数据存储设备可操作地耦合到微处理器并被配置为存储三维图像数据以及预定的保护区域边界和固定对象定义。 GPS接收机可以可操作地耦合到微处理器和GPS天线。 微处理器被配置为执行将三维图像数据与保护区边界和固定对象定义进行比较的LADAR图像分析，以识别一个或多个潜在入侵者。

公开(公告)号：US20120237973A1

公开(公告)日：2012-09-20

申请号：US13484665

申请日：2012-05-31

Applicant: Piotr Bobrowicz ,  W. James Cook ,  Warren Kett

Inventor： Piotr Bobrowicz ,  W. James Cook ,  Warren Kett

IPC: C12P21/00

CPC classification number: C07K16/32 ,  C07K2317/41 ,  C12P21/005

Abstract: A method is described for producing protein compositions having reduced amounts of O-linked glycosylation. The method includes producing the protein in cells cultured in the presence of an inhibitor of Pmt-mediated O-linked glycosylation and/or in the presence of one or more α-1,2-mannosidases.

公开(公告)号：US08188144B2

公开(公告)日：2012-05-29

申请号：US12757717

申请日：2010-04-09

Applicant: Donald Barton McPhail ,  Graeme James Cook ,  Andrew Scott Johnstone

Inventor： Donald Barton McPhail ,  Graeme James Cook ,  Andrew Scott Johnstone

IPC: A61K31/35 ,  A61K31/38 ,  A61K31/40 ,  C07D315/00 ,  C07D207/38

CPC classification number: C07D311/62 ,  A01N1/02 ,  A01N1/0226 ,  C07D207/36 ,  C07D215/22 ,  C07D307/58 ,  C07D311/30 ,  C07D333/32 ,  C07D335/06 ,  C12N5/0606 ,  C12N2501/999

Abstract: The invention is directed to compounds of Formula (I) or salts thereof. The invention is also directed to use of the compounds of formula (I) in the in vitro preservation of living animal cells. The living cells can be isolated cells, such as stem cells, or groups of cells such as tissue or an organ.

Abstract translation: 本发明涉及式（I）的化合物或其盐。 本发明还涉及式（I）化合物在活体动物细胞的体外保存中的用途。 活细胞可以是分离的细胞，例如干细胞或细胞组，例如组织或器官。

公开(公告)号：US20120094384A1

公开(公告)日：2012-04-19

申请号：US13260248

申请日：2010-04-09

Applicant: Donald Barton McPhail ,  Graeme James Cook ,  Andrew Scott Johnstone

Inventor： Donald Barton McPhail ,  Graeme James Cook ,  Andrew Scott Johnstone

IPC: C12N5/071 ,  C12N5/077 ,  C12N5/079

CPC classification number: C12N5/0606 ,  C12N2501/999

Abstract: The present invention provides a method for differentiating an undifferentiated cell, said method comprising contacting an undifferentiated cell with certain compounds of Formula (I) or a salt thereof.

Abstract translation: 本发明提供了一种分化未分化细胞的方法，所述方法包括使未分化细胞与某些式（I）化合物或其盐接触。

公开(公告)号：US20100092941A1

公开(公告)日：2010-04-15

申请号：US12316383

申请日：2008-12-10

Applicant: Rachel Meyers ,  William James Cook ,  Mark Williamson ,  Laura A. Rudolph-Owen ,  Ruth Gimeno

Inventor： Rachel Meyers ,  William James Cook ,  Mark Williamson ,  Laura A. Rudolph-Owen ,  Ruth Gimeno

IPC: C12Q1/70 ,  C07H21/00 ,  C12N15/63 ,  C12N5/00 ,  C12N1/00 ,  C12P21/00 ,  C07K7/08 ,  C07K14/00 ,  C07K16/00 ,  G01N33/53 ,  G01N33/68 ,  C12Q1/02

CPC classification number: C12N9/0004 ,  C07K2319/00 ,  C12N9/0006

Abstract: The invention provides isolated nucleic acids molecules, designated DHDR nucleic acid molecules, which encode novel DHDR-related dehydrogenase molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing DHDR nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DHDR gene has been introduced or disrupted. The invention still further provides isolated DHDR proteins, fusion proteins, antigenic peptides and anti-DHDR antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

Abstract translation: 本发明提供编码新型DHDR相关脱氢酶分子的分离的核酸分子，命名为DHDR核酸分子。 本发明还提供了反义核酸分子，含有DHDR核酸分子的重组表达载体，其中引入了表达载体的宿主细胞，以及DHDR基因导入或破坏的非人类转基因动物。 本发明还进一步提供了分离的DHDR蛋白，融合蛋白，抗原肽和抗DHDR抗体。 还提供了利用本发明组合物的诊断方法。

公开(公告)号：US07611879B2

公开(公告)日：2009-11-03

申请号：US11981466

申请日：2007-10-31

Applicant: Rachel E. Meyers ,  William James Cook

Inventor： Rachel E. Meyers ,  William James Cook

IPC: C12N9/04 ,  C07K1/00

CPC classification number: A61K38/16 ,  A01K2217/05 ,  A61K38/4813 ,  A61K39/00 ,  A61K2039/53 ,  C07K14/47 ,  C07K2319/00 ,  C12N9/0008 ,  C12N9/12 ,  C12N9/16 ,  C12N9/20 ,  C12N9/6416 ,  C12N9/6424 ,  C12N9/6491 ,  C12N9/93 ,  C12Q1/25 ,  C12Q1/37 ,  C12Q1/6883 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Y603/02019 ,  G01N33/5008 ,  G01N33/5011 ,  G01N33/502 ,  G01N33/573 ,  G01N33/68 ,  G01N2500/10 ,  Y10T436/143333 ,  A61K2300/00

Abstract: The invention provides isolated nucleic acids molecules, designated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 gene has been introduced or disrupted. The invention still further provides isolated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 proteins, fusion proteins, antigenic peptides and anti-27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

Abstract translation: 本发明提供分离的核酸分子，命名为27877,18080,14081,32140,50352,16658,14223,16002,50566,65552和65577核酸分子。 本发明还提供反义核酸分子，含有27877,18080,14081,32140,50502,16658,14223,16002,50566,65552和65577核酸分子的重组表达载体，已经引入表达载体的宿主细胞，以及 已经引入或破坏了27877,18080,14081,32140,50352,16658,14223,16002,50566,65552或65577基因的非人类转基因动物。 本发明还进一步提供分离的27877,18080,14081,32140,50352,16658,14223,16002,50566,65552或65577蛋白，融合蛋白，抗原肽和抗27877,18080,14081,32140,50352,16658,14223 ，16002,50566,65552或65577抗体。 还提供了利用本发明组合物的诊断和治疗方法。

公开(公告)号：US07494793B2

公开(公告)日：2009-02-24

申请号：US11335810

申请日：2006-01-19

Applicant: Rachel Meyers ,  William James Cook

Inventor： Rachel Meyers ,  William James Cook

IPC: C12N9/04 ,  C12N15/00 ,  C12Q1/00 ,  C12Q1/68 ,  C12P21/04 ,  C07H21/04

CPC classification number: C12N9/0004 ,  C07K2319/00 ,  C12N9/0006

Abstract: The invention provides isolated nucleic acids molecules, designated DHDR nucleic acid molecules, which encode novel DHDR-related dehydrogenase molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing DHDR nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DHDR gene has been introduced or disrupted. The invention still further provides isolated DHDR proteins, fusion proteins, antigenic peptides and anti-DHDR antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

Abstract translation: 本发明提供编码新型DHDR相关脱氢酶分子的分离的核酸分子，命名为DHDR核酸分子。 本发明还提供了反义核酸分子，含有DHDR核酸分子的重组表达载体，其中引入了表达载体的宿主细胞，以及DHDR基因导入或破坏的非人类转基因动物。 本发明还进一步提供了分离的DHDR蛋白，融合蛋白，抗原肽和抗DHDR抗体。 还提供了利用本发明组合物的诊断方法。