公开(公告)号：US20050015006A1

公开(公告)日：2005-01-20

申请号：US10860707

申请日：2004-06-03

Applicant: Matthias Mitschke ,  Norbert Rahn ,  Dieter Ritter ,  Michael Scheuering

Inventor： Matthias Mitschke ,  Norbert Rahn ,  Dieter Ritter ,  Michael Scheuering

IPC: A61B6/00 ,  A61B6/12 ,  G06T7/00 ,  G06T11/00 ,  A61B5/05 ,  G06K9/00

CPC classification number: A61B6/5235 ,  A61B6/12 ,  A61B6/466 ,  A61B6/481 ,  A61B6/504 ,  G06T7/33 ,  G06T2207/30048

Abstract: In an image post-processing method and apparatus for 3D visualization of 2D/3D fused image data for use in catheter angiography in an endovascular interventional procedure, upon forward movement of a micro-catheter through blood vessel in the interventional procedure, x-ray images are acquired from different projection directions and are subjected to a pattern recognition algorithm for edge-based segmentation of the image regions filled by the micro-catheter, with all remaining image regions being masked out. The segmented projection exposures are prepared by a 3D reconstruction algorithm to obtain an image data set for (pseudo-) three-dimensional representation of the micro-catheter. This image data set are intraoperatively registered and fused with an image data set acquired from an angiographic pre-examination for three-dimensional visualization of the vessel topography. The reconstructed 3D representation of the catheter is mixed into the three-dimensionally prepared representation of endovascular blood vessel sections to be treated.

Abstract translation: 在用于血管内介入手术的导管血管造影术中的2D / 3D融合图像数据的3D可视化的图像后处理方法和装置中，在介入手术中通过血管向前移动微导管时，x射线图像 从不同的投影方向获取，并且经受用于由微导管填充的图像区域的基于边缘的分割的图案识别算法，其中所有剩余的图像区域被掩蔽。 通过3D重建算法准备分段投影曝光以获得微导管的（伪）三维表示的图像数据集。 该图像数据集在术中注册并与从血管造影检查获取的图像数据集合融合，用于血管形态的三维可视化。 导管的重建3D表示被混合到待治疗的血管内血管切片的三维制备的表示中。

公开(公告)号：US5692515A

公开(公告)日：1997-12-02

申请号：US646391

申请日：1996-05-08

Applicant: Norbert Rahn ,  Wolfgang Eck

Inventor： Norbert Rahn ,  Wolfgang Eck

IPC: A61B5/0402 ,  A61B5/0452 ,  A61N1/08 ,  A61N1/362 ,  A61N1/37 ,  A61N1/39 ,  A61B5/04

CPC classification number: A61N1/08 ,  A61B5/0402 ,  A61N1/3702 ,  A61N1/3925

Abstract: In an apparatus for acquiring stimulated action currents of the heart, a stimulation unit emits stimulation signals to the heart. Measured values that are causally influenced by the action currents resulting from the stimulation signals are acquired with a measuring system. The measured values are supplied to a processing unit under the control of a unit connected to the stimulation unit and to the processing unit which supplies the measured values to the processing unit dependent on the stimulation signals.

Abstract translation: 在用于获取心脏的受激动作电流的装置中，刺激单元向心脏发射刺激信号。 由测量系统获取由刺激信号产生的动作电流的因果影响的测量值。 在连接到刺激单元的单元的控制下，将测量值提供给处理单元，以及根据刺激信号将测量值提供给处理单元的处理单元。

公开(公告)号：US08077940B2

公开(公告)日：2011-12-13

申请号：US11725830

申请日：2007-03-20

Applicant: Matthias John ,  Norbert Rahn

Inventor： Matthias John ,  Norbert Rahn

IPC: G06K9/00

CPC classification number: A61B8/12 ,  A61B5/0066 ,  A61B5/0456 ,  A61B8/543 ,  G06T11/005 ,  G06T2211/428

Abstract: The invention relates to a method for reconstructing a three-dimensional target volume, particularly within the human body, in realtime and displaying it, with a three-dimensional reconstruction volume being determined from a basic set comprising a minimum number of two-dimensional images obtained from an image recording device located within the target volume, wherein, when a new image is included in the basic set, locally limited updating at least of the reconstruction volume's partial areas covered by the new image will under a predefined condition be performed and the updated reconstruction volume will be displayed.

Abstract translation: 本发明涉及一种用于重建三维目标体积，特别是在人体内实时地显示三维目标体积的方法，并且显示三维目标体积，其中三维重建体积是从包括最小数目的二维图像获得的基本集合确定的 从位于所述目标体积内的图像记录装置，其中，当在所述基本组中包括新图像时，在执行所述新图像所覆盖的至少所述重建体积的部分区域内的局部限制更新将被执行，并且所述更新 重建体积将被显示。

公开(公告)号：US20110019892A1

公开(公告)日：2011-01-27

申请号：US12840361

申请日：2010-07-21

Applicant: Norbert Rahn ,  Dietrich Till

Inventor： Norbert Rahn ,  Dietrich Till

IPC: G06K9/00

CPC classification number: A61B6/12 ,  A61B6/4441 ,  A61B6/466 ,  A61B6/503 ,  A61B6/504 ,  A61B8/0891 ,  A61B18/1492 ,  A61B2090/065 ,  G06T19/00 ,  G06T2210/41

Abstract: A method for visually supporting an electrophysiological catheter application is provided. An electroanatomical 3D mapping data of a region of interest in the heart is visualized. A 3D image data of the region of interest is captured before the catheter application. A 3D surface profile of objects in the region of interest is extracted from the 3D image data by segmentation. The electroanatomical 3D mapping data and 3D image data forming at least the 3D surface profile is assigned by registration and visualized superimposed on one another. Characteristic parameters are measured for catheter guidance during the catheter application. The characteristic parameters are compared with at least one predefined threshold value and regulation data for catheter guidance is generated as a function of the comparison result. The regulation data is integrally displayed and represented in the superimposed visualization.

Abstract translation: 提供了用于视觉上支持电生理学导管应用的方法。 可视化心脏中感兴趣区域的电解剖3D绘图数据。 在导管应用之前捕获感兴趣区域的3D图像数据。 通过分割从3D图像数据中提取感兴趣区域中的对象的3D表面轮廓。 形成至少3D表面轮廓的电解剖3D图形数据和3D图像数据通过配准分配并且可视化地彼此叠加。 在导管应用期间测量导管引导的特征参数。 将特征参数与至少一个预定义的阈值进行比较，并且作为比较结果的函数产生用于导管引导的调节数据。 调整数据在叠加的可视化中一体地显示和表示。

公开(公告)号：US07792593B2

公开(公告)日：2010-09-07

申请号：US11600976

申请日：2006-11-17

Applicant: Norbert Rahn ,  Jan Boese

Inventor： Norbert Rahn ,  Jan Boese

IPC: A61N1/05

CPC classification number: A61N1/056 ,  A61N2001/0585

Abstract: In a method and system for patient-specific production of a cardiac electrode lead, a 3D representation of the coronary sinus vessel tree is segmented to indicate the interior surface thereof and a representative line from an opening of the coronary sinus vessel tree to an implantation site for the electrode lead, and a computerized model of the electrode is generated that includes deformation properties of the mechanical structure of the electrode lead. A computerized virtual implantation of the electrode through the 3D representation of the coronary sinus vessel tree is implemented using the model and the internal surface and the representative line from which determination is made as to whether an electrode conforming to the model can be guided to and implanted at the implantation site in a medically acceptable manner, or whether modification of the electrode lead is necessary.

Abstract translation: 在用于患者特异性生产心脏电极引线的方法和系统中，冠状窦血管树的3D表示被分割以指示其内表面和从冠状窦血管树的开口到植入部位的代表性线 并且产生电极的计算机化模型，其包括电极引线的机械结构的变形特性。 通过冠状窦血管树的3D表示的电极的电脑化虚拟植入是使用模型和内表面以及代表性线来实现的，其中确定是否能够引导符合模型的电极和植入 在植入部位以医学上可接受的方式，或者是否需要修改电极引线。

公开(公告)号：US07761135B2

公开(公告)日：2010-07-20

申请号：US11636953

申请日：2006-12-11

Applicant: Marcus Pfister ,  Norbert Rahn

Inventor： Marcus Pfister ,  Norbert Rahn

IPC: A61B5/05

CPC classification number: A61B6/504 ,  A61B6/12 ,  G06T5/50 ,  G06T7/33 ,  G06T7/38 ,  G06T2207/10072 ,  G06T2207/10121 ,  G06T2207/20221 ,  G06T2207/30101

Abstract: The present invention relates to a method and a device for correcting motion in imaging during a medical intervention, by which method a 3D tomographic image of a target area for the intervention is first recorded while there are one or more medical instruments in the target area that will remain there during the intervention. During the intervention 2D fluoroscopic images of the target area are recorded and registered with the 3D image. The registration is therein adjusted for each 2D fluoroscopic image in realtime based in each case on the one or more instruments. The 2D fluoroscopic images are then in each case visualized with representations, concurring in terms of perspective, of the 3D image. Virtually error-free overlaying of the 3D image with in each case one 2D fluoroscopic image can be implemented using the present method and associated device.

Abstract translation: 本发明涉及一种用于在医疗介入期间校正成像中的运动的方法和装置，通过该方法首先记录用于干预的目标区域的3D断层图像，同时目标区域中存在一个或多个医疗器械 将在干预期间留在那里。 在干预期间，记录2D目标区域的二维透视图像并将其与3D图像一起登记。 在每个情况下，在一个或多个仪器上实时地对每个2D透视图像进行配准。 然后，2D透视图像在每种情况下可视化，并以透视方式同意3D图像。 在每种情况下，3D图像的几乎无误差的重叠可以使用本方法和相关联的装置来实现一个2D透视图像。

公开(公告)号：US20100104164A1

公开(公告)日：2010-04-29

申请号：US12518123

申请日：2008-04-04

Applicant: Meir Bartal ,  Jan Boese ,  Assaf Govari ,  Matthias John ,  Assaf Preiss ,  Norbert Rahn

Inventor： Meir Bartal ,  Jan Boese ,  Assaf Govari ,  Matthias John ,  Assaf Preiss ,  Norbert Rahn

IPC: G06K9/62

CPC classification number: A61B6/4441 ,  A61B5/1127 ,  A61B6/503 ,  A61B6/583

Abstract: A method and a device for obtaining a volume data set of a mobile tissue or organ of a patient by a C-arm X-ray device are provided. An electromagnetic sensor of a position detection system is arranged indirectly on the tissue or organ. The X-ray device obtains a plurality of X-ray projections from the tissue or organ from various projection directions. A first method consists of reconstructing a volume data set from the X-ray projections, in which the electromagnetic sensor adopts a position characterizing a displacement phase of the tissue or organ. A second method consists of reconstructing a volume data set from the X-ray projections captured when the electromagnetic sensor was located in a position characterizing a displacement phase of the tissue or organ. A third method does not capture an X-ray projection for the reconstruction if the electromagnetic sensor is located in a position characterizing a displacement phase.

Abstract translation: 提供了一种用于通过C臂X射线装置获得患者的移动组织或器官的体积数据集的方法和装置。 位置检测系统的电磁传感器间接地布置在组织或器官上。 X射线装置从各种投影方向从组织或器官获得多个X射线投射。 第一种方法包括从X射线投影重建体数据集，其中电磁传感器采用表征组织或器官位移阶段的位置。 第二种方法包括当电磁传感器位于表征组织或器官的位移阶段的位置时，从所捕获的X射线投影中重建体数据集。 如果电磁传感器位于表征位移相位置的位置，则第三种方法不能捕获用于重建的X射线投影。

公开(公告)号：US07578787B2

公开(公告)日：2009-08-25

申请号：US11040468

申请日：2005-01-21

Applicant: Jan Boese ,  Martin Kleen ,  Norbert Rahn

Inventor： Jan Boese ,  Martin Kleen ,  Norbert Rahn

IPC: A61B1/00 ,  A61M31/00 ,  A61M25/00

CPC classification number: A61M25/0105 ,  A61M25/0155 ,  A61M2025/0161

Abstract: Catheter device, comprising a catheter (2) for introduction into a hollow organ, especially a vessel, with a number of bending elements (12, 12a-12f, 12a′-12e′) arranged around the longitudinal axis of the catheter and distributed over at least a part of the catheter length, which can be activated separately for a specified change of shape via a control device (5), as well as a number of bending sensors (15, 15a-15e, 15a′-15e′) arranged around the longitudinal axis of the catheter and distributed over at least a part of the catheter length communicating with a control device (5), with the control device (5) being embodied to determine the given geometrical shape of the catheter (2) on the basis of the bending sensor signals and to determine the change of shape of the bending elements (12, 12a-12f, 12a′-12e′) necessary for a movement of the catheter (2) by a forward movement length preferably specifiable on the user side to enable the catheter (2) to move by itself at least in part, by explicit bend-dependent force application to the wall of the organ (16).

Abstract translation: 导管装置，包括用于引入中空器官，特别是血管的导管（2），其具有围绕导管的纵向轴线布置的多个弯曲元件（12,12a-12f，12a'-12e'），并分布在 导管长度的至少一部分，其可以通过控制装置（5）以及多个弯曲传感器（15,15a-15e，15a'-15e'）分别被激活以形成规定的形状变化， 围绕所述导管的纵向轴线并且分布在与控制装置（5）连通的导管长度的至少一部分上，所述控制装置（5）被实施为确定所述导管（2）的给定几何形状 弯曲传感器信号的基础并且确定导管（2）移动所需的弯曲元件（12,12a-12f，12a'-12e'）的形状的变化，该向前移动长度优选地可以在用户上指定 侧使得导管（​​2）至少部分地移动到其自身 明显的弯曲依赖力施加到器官的壁（16）。

公开(公告)号：US07460642B2

公开(公告)日：2008-12-02

申请号：US11478464

申请日：2006-06-29

Applicant: Jan Boese ,  Norbert Rahn ,  Bernhard Sandkamp

Inventor： Jan Boese ,  Norbert Rahn ,  Bernhard Sandkamp

IPC: H05G1/42

CPC classification number: A61B6/12 ,  A61B6/06 ,  A61B6/4441 ,  A61B6/542 ,  A61B6/545

Abstract: With a method for generating an x-ray image sequence for supporting an intervention on a patient with a catheter or guide wire for instance, automatic recognition of the catheter is carried out with recorded x-ray images using a computer system. The x-ray image recording parameters are changed on the basis of the determined quality of the imaging of the object, with the x-ray device preferably being automatically activated with the changed x-ray image recording parameters, to record x-ray images. The doctor can therefore concentrate on the actual intervention and does not have to worry about operating the x-ray device.

Abstract translation: 通过使用例如用导管或引导线产生用于支持对患者的介入的X射线图像序列的方法，使用计算机系统用记录的X射线图像进行导管的自动识别。 基于所确定的物体的成像质量来改变X射线图像记录参数，其中X射线装置优选地通过改变的X射线图像记录参数被自动激活，以记录x射线图像。 因此，医生可以专注于实际的干预，而不必担心操作x射线装置。

公开(公告)号：US07366563B2

公开(公告)日：2008-04-29

申请号：US11012971

申请日：2004-12-14

Applicant: Martin Kleen ,  Marcus Pfister ,  Norbert Rahn

Inventor： Martin Kleen ,  Marcus Pfister ,  Norbert Rahn

IPC: A61B5/05

CPC classification number: A61B5/0071 ,  A61B5/0073 ,  A61B5/0084 ,  A61B5/06 ,  A61B5/062 ,  A61B5/7285 ,  A61B34/20 ,  A61B90/36 ,  A61B90/361 ,  A61B2034/2051 ,  A61B2090/367 ,  A61B2090/373

Abstract: Catheter device for insertion into an area being examined, in particular into a vessel or cavity-containing organ in the body of a person or animal, wherein in the area of the catheter tip a device (3) is provided for emitting excitation light for light-optically exciting an area being examined surrounding the catheter tip, furthermore a device (3) is provided for collecting response light emitted, owing to excitation, from the area being examined, and furthermore a position sensor (13, 24, 27) is provided enabling the catheter tip's spatial position and/or orientation to be registered in a system of coordinates of a position-registering system (7, 14).

Abstract translation: 用于插入被检查区域的导管装置，特别是插入人或动物身体中的容器或含腔器官中，其中在导管末端的区域中设置有用于发射光的激发光的装置（3） - 光学激发围绕导管尖端的被检查的区域，此外，提供了一种装置（3），用于从被检查的区域收集由于激发而发射的响应光，并且还提供了位置传感器（13,24,27） 使得导管末端的空间位置和/或取向能够登记在位置登记系统（7,14）的坐标系统中。