公开(公告)号：US20050280774A1

公开(公告)日：2005-12-22

申请号：US11188069

申请日：2005-07-22

Applicant: Arthur Back

Inventor： Arthur Back

IPC: G02C7/04

CPC classification number: G02C7/04 ,  G02C7/048

Abstract: A contact lens having a rotational stabilization mechanism thereon, such as prism ballast, and a thickness profile that reduces the torque imparted on the lens by the action of the eyelids, especially for stabilizing toric lenses. The prism ballast is provided on one or more portions of the anterior face of the lens such that the lens body has a uniform thickness of within 10% along horizontal cross-sections. The anterior face of the lens may be segregated into a peripheral zone, an inner zone circumscribed by the peripheral zone, and a central optic zone. The prism ballast portion is provided within the inner zone, which may be further subdivided into a superior portion, an intermediate portion proximate the optic zone, and an inferior portion. The ballast portion increases in thickness along a superior-inferior line parallel to a vertical meridian, and has a substantially uniform thickness perpendicular thereto. The peripheral zone may be tapered, and have a rounded edge. The rate of thickness change across any portion of the peripheral zone is less than about 250 μm/mm.

公开(公告)号：US20050080484A1

公开(公告)日：2005-04-14

申请号：US10661400

申请日：2003-09-12

Applicant: J. Marmo ,  Arthur Back

Inventor： J. Marmo ,  Arthur Back

IPC: A61F2/14 ,  A61F9/00 ,  A61F9/013 ,  A61L27/38

CPC classification number: A61F2/145 ,  A61F9/0017 ,  A61F9/013 ,  A61L27/3604 ,  A61L27/3641 ,  A61L27/3813 ,  A61L27/3839 ,  A61L27/3895 ,  A61L2430/16 ,  Y10S623/906

Abstract: A corneal appliance that is placed over an eye has a lens body and epithelial cells secured over the lens body. The epithelial cells of the appliance may be derived from cultured cells, including stem cells, such as limbal stem cells, or epithelial cell lines, or may include at least a portion of the epithelium of the eye on which the appliance is placed. The corneal appliance may have a cellular attachment element between the lens body and the epithelial cells to facilitate attachment of the epithelial cells over the lens body. The corneal appliance is intended to be used on a deepithelialized eye, which may be an eye that has had the epithelium fully or partially removed. The corneal appliance may be used to improve vision. Methods of producing the corneal appliance and of improving vision are also disclosed.

Abstract translation: 放置在眼睛上方的角膜器具具有固定在镜体上的透镜体和上皮细胞。 器具的上皮细胞可以衍生自培养的细胞，包括干细胞，例如角膜缘干细胞或上皮细胞系，或可以包括放置该器具的眼睛的至少一部分上皮。 角膜器具可以在透镜体和上皮细胞之间具有细胞附着元件，以促进上皮细胞在透镜体上的附着。 角膜器具旨在用于深层上皮化的眼睛，其可以是具有完全或部分去除上皮的眼睛。 角膜器具可用于改善视力。 还公开了生产角膜器具和改善视力的方法。

公开(公告)号：US06595639B1

公开(公告)日：2003-07-22

申请号：US09709132

申请日：2000-11-10

Applicant: Arthur Ho ,  Arthur Back

Inventor： Arthur Ho ,  Arthur Back

IPC: G02C702

CPC classification number: B29D11/00432 ,  G02C7/04

Abstract: Methods for producing a junctionless ophthalmic lens are provided. Additionally, ophthalmic lenses having junctionless, three dimensional surfaces, for example, asymmetrical anterior and/or posterior surfaces, as well as molding tools used in the production of such lenses, are also provided. The method generally include providing sample data points to define a surface contour, and interpolating between these data points using an algorithm to produce a simulated three dimensional surface. The simulated three dimensional surface is used in producing an ophthalmic lens, for example, in cast molding a contact lens.

Abstract translation: 提供无连接眼科镜片的制造方法。 此外，还提供了具有无连接的三维表面，例如不对称的前表面和/或后表面的眼镜片，以及用于制造这种镜片的成型工具。 该方法通常包括提供样本数据点以定义表面轮廓，并且使用算法在这些数据点之间内插以产生模拟的三维表面。 模拟的三维表面用于制造眼科镜片，例如在模制成型的隐形眼镜中。

公开(公告)号：US09121998B2

公开(公告)日：2015-09-01

申请号：US13983578

申请日：2012-02-23

Applicant: Charlie Chen ,  Yuwen Liu ,  Yuan Xu ,  Ying Zheng ,  Junhao Ge ,  Li Yao ,  Arthur Back

Inventor： Charlie Chen ,  Yuwen Liu ,  Yuan Xu ,  Ying Zheng ,  Junhao Ge ,  Li Yao ,  Arthur Back

IPC: C08L101/14 ,  C08L83/04 ,  G02C7/04 ,  G02B1/04

CPC classification number: G02B1/043 ,  C08L51/085 ,  C08L83/04 ,  C08L101/14

Abstract: Silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including 30-60 unit parts by weight of a hydrophilic monomer(s) having one N-vinyl group, 10 to 50 unit parts by weight of 2-hydroxyethyl methacrylate (HEMA), and a first siloxane monomer component comprising a siloxane monomer of formula (1) as described herein or a siloxane monomer of formula (2) as described herein or a siloxane monomer of formula (3) as described herein or any combination thereof, where the total amount of siloxane monomer(s) present in the polymerizable composition is from 15 to 40 unit parts by weight. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.

Abstract translation: 描述了硅酮水凝胶隐形眼镜。 透镜衍生自可聚合组合物，其包含30-60单位重量份的具有一个N-乙烯基的亲水性单体，10-50单位重量份的甲基丙烯酸2-羟乙酯（HEMA）和第一个硅氧烷 单体组分，其包含本文所述的式（1）的硅氧烷单体或本文所述的式（2）的硅氧烷单体或本文所述的式（3）的硅氧烷单体或其任何组合，其中硅氧烷单体的总量 存在于聚合性组合物中的重量比为15〜40单位份。 还描述了硅胶水凝胶隐形眼镜的批次和制备硅酮水凝胶隐形眼镜的方法。

公开(公告)号：US08899746B2

公开(公告)日：2014-12-02

申请号：US13318630

申请日：2010-05-03

Applicant: Arthur Back

Inventor： Arthur Back

IPC: G02C7/04

CPC classification number: G02C7/041 ,  G02C7/042 ,  G02C2202/24

Abstract: Methods for slowing progression of myopia or hyperopia of human patients include a step of providing contact lenses. The contact lenses have two or more refractive powers. A first refractive power provides clear visual acuity and a second refractive power provides a defocused retinal image to the human patient. The methods involve providing first and second sets of the contact lenses, the contact lenses of the second set have a different optical design than the contact lenses of the first set. With the present methods, an eye care practitioner is able to select one or more contact lenses from the second set of contact lenses based on one or more ocular parameters of the patient, one or more responses of the patient to the contact lens of the first set, or both, to provide an improved clinical benefit to the patient compared to the benefit provided by the first set of contact lenses.

Abstract translation: 减慢人类近视或远视进展的方法包括提供隐形眼镜的步骤。 隐形眼镜具有两个或更多个屈光力。 第一屈光力提供清晰的视力，第二屈光力提供了散焦视网膜图像给人类患者。 所述方法包括提供第一组和第二组隐形眼镜，第二组的隐形眼镜具有与第一组的隐形眼镜不同的光学设计。 根据本方法，眼科医生能够基于患者的一个或多个眼部参数从第二组隐形眼镜中选择一个或多个隐形眼镜，患者对第一个隐形眼镜的隐形眼镜的一个或多个响应 设置或两者，以与第一组隐形眼镜提供的益处相比，为患者提供改善的临床益处。

公开(公告)号：US08865789B2

公开(公告)日：2014-10-21

申请号：US13404035

申请日：2012-02-24

Applicant: Li Yao ,  Ye Hong ,  Yuwen Liu ,  Charlie Chen ,  Charles A. Francis ,  Arthur Back

Inventor： Li Yao ,  Ye Hong ,  Yuwen Liu ,  Charlie Chen ,  Charles A. Francis ,  Arthur Back

IPC: C08L101/14 ,  B65B55/02 ,  G02C7/04 ,  C08G77/04 ,  G02B1/04

CPC classification number: G02B1/043 ,  C08L83/12 ,  C08L101/14 ,  C08L33/10 ,  C08L33/08

Abstract: Silicone hydrogel contact lenses that have good dimensional stability, are ophthalmically-acceptable, and can be manufactured without the use of alcohol solvents are formed from the reaction product of a polymerizable composition comprising at least one mono-functional acrylate-containing siloxane monomer having a molecular weight of less than 2,000; at least one bi-functional acrylate-containing siloxane monomer having a molecular weight of at least 3,000; and at least one hydrophilic vinyl-containing monomer, wherein the polymerizable composition has a molar ratio of total amount of mono-functional acrylate-containing siloxane monomer to total amount of bi-functional acrylate-containing siloxane monomer of at least 30:1, respectively.

Abstract translation: 由可聚合组合物的反应产物形成具有良好的尺寸稳定性的眼科学可接受的硅酮水凝胶隐形眼镜，并且可以制造不含醇溶剂的可聚合组合物，该可聚合组合物包含至少一种含单分子丙烯酸酯的含有单官能丙烯酸酯的硅氧烷单体 重量小于2000; 至少一种分子量至少为3,000的含二官能丙烯酸酯的硅氧烷单体; 和至少一种亲水性含乙烯基单体，其中所述可聚合组合物的含单体官能丙烯酸酯的硅氧烷单体的总量与含二官能丙烯酸酯的硅氧烷单体的总量的摩尔比分别为至少30:1 。

公开(公告)号：US08820928B2

公开(公告)日：2014-09-02

申请号：US13404033

申请日：2012-02-24

Applicant: Arthur Back ,  David Robert Morsley ,  Richard Rogers ,  Sarah Almond ,  Charlie Chen ,  Yuwen Liu ,  Charles A. Francis ,  Ye Hong

Inventor： Arthur Back ,  David Robert Morsley ,  Richard Rogers ,  Sarah Almond ,  Charlie Chen ,  Yuwen Liu ,  Charles A. Francis ,  Ye Hong

IPC: G02C7/04 ,  C08L83/04 ,  G02B1/04 ,  C08G77/46 ,  C08G77/20

CPC classification number: C08L83/04 ,  C08G77/20 ,  C08G77/46 ,  G02B1/043 ,  C08L101/14 ,  C08L83/12

Abstract: Silicone hydrogel contact lenses are produced without using volatile organic solvents to extract materials from the polymerized contact lens bodies, and instead are washed with aqueous liquids. The silicone hydrogel contact lenses so produced have ophthalmically wettable lens surfaces such that less than five percent of a batch of twenty or more such silicone hydrogel contact lenses have visually identifiable non-wetting spots when the contact lenses are located on eyes of subjects.

Abstract translation: 制造硅氧烷水凝胶隐形眼镜，而不使用挥发性有机溶剂从聚合的隐形眼镜体提取物质，而是用含水液体洗涤。 如此制造的硅酮水凝胶隐形眼镜具有眼睛可润湿的透镜表面，使得当隐形眼镜位于受试者的眼睛上时，少于一批二十或更多个这种硅氧水凝胶隐形眼镜的百分之五具有视觉上可识别的非润湿斑点。

公开(公告)号：US20140018465A1

公开(公告)日：2014-01-16

申请号：US13985109

申请日：2012-02-23

Applicant: Yuwen Liu ,  Charlie Chen ,  Ye Hong ,  Charles A. Francis ,  Li Yao ,  Arthur Back

Inventor： Yuwen Liu ,  Charlie Chen ,  Ye Hong ,  Charles A. Francis ,  Li Yao ,  Arthur Back

IPC: G02B1/04

CPC classification number: G02B1/043 ,  C08F283/065 ,  C08L51/085 ,  C08L101/14

Abstract: Silicone hydrogel contact lenses having a high water content are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, R1 of formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (1) is independently either a hydrogen atom or a methyl group; the lenses also include units derived from a second siloxane monomer having a number average molecular weight of at least 7,000 daltons, and at least one vinyl-containing cross-linking agent. The lenses have average equilibrium water contents from about 30% wt/wt to about 70% wt/wt when fully hydrated. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.

Abstract translation: 描述了具有高水含量的硅氧烷水凝胶隐形眼镜。 透镜衍生自包含由式（1）表示的第一硅氧烷单体的可聚合组合物：其中式（1）的m表示3至10的一个整数，式（1）的n表示1至10的整数，R 1 式（1）的烷基是碳原子数为1〜4的烷基，式（1）的各R 2独立地为氢原子或甲基。 透镜还包括衍生自数均分子量为至少7,000道尔顿的第二硅氧烷单体的单元和至少一种含乙烯基交联剂。 当完全水合时，透镜具有约30重量％至约70重量％的平均水含量。 还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

公开(公告)号：US20130201443A1

公开(公告)日：2013-08-08

申请号：US13746490

申请日：2013-01-22

Applicant: Arthur Back ,  Kuang-mon Ashley Tuan

Inventor： Arthur Back ,  Kuang-mon Ashley Tuan

IPC: G02C7/04

CPC classification number: G02C7/041 ,  G02C7/027 ,  G02C7/042 ,  G02C7/044

Abstract: Multifocal contact lenses and methods and uses are described. The multifocal contact lenses include an optic zone. The optic zone has an aspheric power profile that provides a near vision refractive power and a distance vision refractive power, and provides an Add power that corresponds to the difference between the near vision refractive power and the distance vision refractive power. The multifocal contact lenses can improve binocular vision of presbyopic subjects by being prescribed such that the non-dominant eye contact lens is over-corrected for distance vision, and both multifocal contact lenses are under-corrected for the Add power requirement of the subject. Batches and sets of multifocal contact lenses are also described.

公开(公告)号：US20130201442A1

公开(公告)日：2013-08-08

申请号：US13747510

申请日：2013-01-23

Applicant: Arthur Back

Inventor： Arthur Back

IPC: G02C7/04

CPC classification number: G02C7/041 ,  G02C7/027 ,  G02C7/042 ,  G02C7/044 ,  G02C2202/08

Abstract: Multifocal contact lenses and methods and uses are described. The multifocal contact lenses include an optic zone. The optic zone has an aspheric power profile that provides a near vision refractive power and a distance vision refractive power, and provides an Add power that corresponds to the difference between the near vision refractive power and the distance vision refractive power. The multifocal contact lenses can improve binocular vision of presbyopic subjects by being prescribed such that the non-dominant eye contact lens is over-corrected for distance vision, and both multifocal contact lenses are under-corrected for the Add power requirement of the subject. Batches and sets of multifocal contact lenses are also described.

Abstract translation: 描述了多焦点隐形眼镜及其方法和用途。 多焦点隐形眼镜包括视区。 光学区具有非球面光焦度分布，其提供近视折射力和距离视力屈光力，并且提供对应于近视力屈光度与距离视力屈光力之间的差的加力。 多焦点隐形眼镜可以通过规定来改善远视对象的双目视觉，使得非优势眼睛隐形眼镜对于距离视力进行过度校正，并且对于受试者的增加功率要求而言，两焦点隐形眼镜都未被校正。 还描述了多焦点隐形眼镜的批次和组。