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41.发明授权Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer 有权核酸和相应的标题为161P2F10B的蛋白质可用于治疗和检测癌症公开(公告)号：US07405290B2
公开(公告)日：2008-07-29
申请号：US10860769
申请日：2004-06-02
申请人： Pia M. Challita-Eid , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Aya Jakobovits
发明人： Pia M. Challita-Eid , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Aya Jakobovits
IPC分类号： C07H21/04
CPC分类号： C07K14/47 , A61K39/00 , C07K16/40 , C12N9/16 , C12Q1/6886 , C12Q2600/158 , Y02A50/466
摘要： A gene (designated 161P2F10B) and its encoded protein are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in the cancers listed in Table I. Consequently, 161P2F10B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 161P2F10B gene or fragment thereof, or its encoded protein or a fragment thereof, can be used to elicit a humoral or cellular immune response.
摘要翻译： 描述了一种基因（命名为161P2F10B）及其编码的蛋白质，其中161P2F10B在正常成人组织中表现出组织特异性表达，其在表I中列出的癌症中异常表达。因此，161P2F10B提供诊断，预后，预防和/或治疗靶标 为癌症。 161P2F10B基因或其片段或其编码的蛋白质或其片段可用于引发体液或细胞免疫应答。
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42.发明申请NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 193P1E1B USEFUL IN TREATMENT AND DETECTION OF CANCER 审中-公开核酸和相关蛋白193P1E1B被用于治疗和检测癌症公开(公告)号：US20120202208A1
公开(公告)日：2012-08-09
申请号：US13450405
申请日：2012-04-18
申请人： Arthur B. RAITANO , Pia M. Challita-Eid , Mary Faris , Rene S. Hubert , Wangmao Ge , Aya Jakobovits
发明人： Arthur B. RAITANO , Pia M. Challita-Eid , Mary Faris , Rene S. Hubert , Wangmao Ge , Aya Jakobovits
IPC分类号： C12Q1/68 , G01N33/574
CPC分类号： C07K16/30 , A61K2039/505 , C07K2317/34 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , Y02A50/466
摘要： A novel gene 0193P1E1B (also designated 193P1E1B) and its encoded protein, and variants thereof, are described wherein 193P1E1B exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 193P1E1B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 193P1E1B gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 193P1E1B can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因0193P1E1B（也称为193P1E1B）及其编码的蛋白质及其变体，其中193P1E1B在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，193P1E1B提供诊断， 癌症的预后，预防和/或治疗靶标。 193P1E1B基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与193P1E1B反应的抗体或T细胞可用于主动或被动免疫。
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43.发明授权Nucleic acid and corresponding protein entitled 184P1E2 useful in treatment and detection of cancer 失效核酸和相应的题为184P1E2的蛋白质可用于治疗和检测癌症公开(公告)号：US08168187B2
公开(公告)日：2012-05-01
申请号：US12985245
申请日：2011-01-05
申请人： Pia M. Challita-Eid , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
发明人： Pia M. Challita-Eid , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
IPC分类号： A61K39/395 , C07K16/30 , C12N5/00
CPC分类号： C07K14/47 , A61K38/00 , C12N9/78 , Y10T436/25
摘要： A novel gene (designated 184P1E2) and its encoded protein, and variants thereof, are described wherein 184P1E2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 184P1E2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 184P1E2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 184P1E2 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为184P1E2）及其编码的蛋白及其变体，其中184P1E2在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，184P1E2提供诊断，预后， 癌症的预防和/或治疗靶标。 184P1E2基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与184P1E2反应的抗体或T细胞可用于主动或被动免疫。
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44.发明申请NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 161P2F10B USEFUL IN TREATMENT AND DETECTION OF CANCER 有权核酸和相关蛋白161P2F10B可用于治疗和检测癌症公开(公告)号：US20110287016A1
公开(公告)日：2011-11-24
申请号：US13153336
申请日：2011-06-03
申请人： Aya JAKOBOVITS , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Wangmao Ge , Karen Jene Meyrick Morrison , Robert Kendall Morrison , Pia M. Challita-Eid
发明人： Aya JAKOBOVITS , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Wangmao Ge , Karen Jene Meyrick Morrison , Robert Kendall Morrison , Pia M. Challita-Eid
CPC分类号： C07K16/30 , A61K31/7088 , A61K39/00 , A61K51/1045 , A61K2039/505 , C07K14/47 , C07K16/18 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3061 , C07K16/3069 , C07K16/40 , C07K2317/20 , C07K2317/33 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2319/30 , C12N9/16 , C12Q1/6886 , C12Q2600/158 , G01N33/57492 , Y02A50/466
摘要： A novel gene 0161P2F10B (also designated 161P2F10B) and its encoded protein, and variants thereof, are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 161P2F10B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 161P2F10B gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 161P2F10B can be used in active or passive immunization.
摘要翻译： 描述了新颖的基因0161P2F10B（也称为161P2F10B）及其编码的蛋白质及其变体，其中161P2F10B在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，161P2F10B提供了诊断， 癌症的预后，预防和/或治疗靶标。 161P2F10B基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与161P2F10B反应的抗体或T细胞可用于主动或被动免疫。
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45.发明授权Nucleic acid and corresponding protein entitled 151P3D4 useful in treatment and detection of cancer 失效核酸和相应的标题为151P3D4的蛋白质可用于治疗和检测癌症公开(公告)号：US07960527B2
公开(公告)日：2011-06-14
申请号：US12687768
申请日：2010-01-14
申请人： Pia M. Challita-Eid , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
发明人： Pia M. Challita-Eid , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
IPC分类号： C07H21/04
CPC分类号： C07K14/47 , A61K38/00 , C12N9/78 , Y10T436/25
摘要： A novel gene (designated 151P3D4) and its encoded protein, and variants thereof, are described wherein 151P3D4 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 151P3D4 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 151P3D4 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 151P3D4 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为151P3D4）及其编码的蛋白及其变体，其中151P3D4在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，151P3D4提供诊断，预后， 癌症的预防和/或治疗靶标。 151P3D4基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与151P3D4反应的抗体或T细胞可用于主动或被动免疫。
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46.发明申请NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 184P1E2 USEFUL IN TREATMENT AND DETECTION OF CANCER 失效核酸和相关蛋白质184P1E2有用的治疗和检测癌症公开(公告)号：US20110110952A1
公开(公告)日：2011-05-12
申请号：US12985245
申请日：2011-01-05
申请人： Pia M. CHALLITA-EID , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
发明人： Pia M. CHALLITA-EID , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
CPC分类号： C07K14/47 , A61K38/00 , C12N9/78 , Y10T436/25
摘要： A novel gene (designated 184P1E2) and its encoded protein, and variants thereof, are described wherein 184P1E2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 184P1E2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 184P1E2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 184P1E2 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为184P1E2）及其编码的蛋白及其变体，其中184P1E2在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，184P1E2提供诊断，预后， 癌症的预防和/或治疗靶标。 184P1E2基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与184P1E2反应的抗体或T细胞可用于主动或被动免疫。
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47.发明申请NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 161P2F10B USEFUL IN TREATMENT AND DETECTION OF CANCER 有权核酸和相关蛋白161P2F10B可用于治疗和检测癌症公开(公告)号：US20100158934A1
公开(公告)日：2010-06-24
申请号：US12641261
申请日：2009-12-17
申请人： Aya Jakobovits , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Wangmao Ge , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Pia M. Challita-Eid
发明人： Aya Jakobovits , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Wangmao Ge , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Pia M. Challita-Eid
IPC分类号： A61K39/00 , C07K16/00 , C12N5/16 , C12N15/74 , C12Q1/68 , C12N5/071 , C07K14/00 , G01N33/567 , A61P37/04 , A61P35/00
CPC分类号： C07K16/30 , A61K31/7088 , A61K39/00 , A61K51/1045 , A61K2039/505 , C07K14/47 , C07K16/18 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3061 , C07K16/3069 , C07K16/40 , C07K2317/20 , C07K2317/33 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2319/30 , C12N9/16 , C12Q1/6886 , C12Q2600/158 , G01N33/57492 , Y02A50/466
摘要： A novel gene 0161P2F10B (also designated 161P2F10B) and its encoded protein, and variants thereof, are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 161P2F10B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 161P2F10B gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 161P2F10B can be used in active or passive immunization.
摘要翻译： 描述了新颖的基因0161P2F10B（也称为161P2F10B）及其编码的蛋白质及其变体，其中161P2F10B在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，161P2F10B提供了诊断， 癌症的预后，预防和/或治疗靶标。 161P2F10B基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与161P2F10B反应的抗体或T细胞可用于主动或被动免疫。
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48.发明申请NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 205P1B5 USEFUL IN TREATMENT AND DETECTION OF CANCER 审中-公开核酸和相关蛋白205P1B5被用于治疗和检测癌症公开(公告)号：US20100086985A1
公开(公告)日：2010-04-08
申请号：US12627998
申请日：2009-11-30
CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , C07K14/47 , G01N33/57484 , Y02A50/466
摘要： A novel gene (designated 205P1B5) and its encoded protein are described. While 205P1B5 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in prostate cancer. Consequently, 205P1B5 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 205P1B5 gene or fragment thereof, or its encoded protein or a fragment thereof, can be used to elicit an immune response.
摘要翻译： 描述了一种新型基因（命名为205P1B5）及其编码的蛋白质。 虽然205P1B5在正常成人组织中表现出组织特异性表达，但在前列腺癌中异常表达。 因此，205P1B5提供了癌症的诊断，预后，预防和/或治疗靶点。 205P1B5基因或其片段或其编码的蛋白质或其片段可用于引发免疫应答。
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49.发明授权Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer 有权核酸和相应的标题为161P2F10B的蛋白质可用于治疗和检测癌症公开(公告)号：US07655234B2
公开(公告)日：2010-02-02
申请号：US11097912
申请日：2005-04-01
申请人： Pia M. Challita-Eid , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Aya Jakobovits
发明人： Pia M. Challita-Eid , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Aya Jakobovits
IPC分类号： A61K39/00
CPC分类号： C07K16/30 , A61K31/7088 , A61K39/00 , A61K51/1045 , A61K2039/505 , C07K14/47 , C07K16/18 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3061 , C07K16/3069 , C07K16/40 , C07K2317/20 , C07K2317/33 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2319/30 , C12N9/16 , C12Q1/6886 , C12Q2600/158 , G01N33/57492 , Y02A50/466
摘要： A gene (designated 161P2F10B) and its encoded protein are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in the cancers listed in Table I. Consequently, 161P2F10B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 161P2F10B gene or fragment thereof, or its encoded protein or a fragment thereof, can be used to elicit a humoral or cellular immune response.
摘要翻译： 描述了一种基因（命名为161P2F10B）及其编码的蛋白质，其中161P2F10B在正常成人组织中表现出组织特异性表达，其在表I中列出的癌症中异常表达。因此，161P2F10B提供诊断，预后，预防和/或治疗靶标 为癌症。 161P2F10B基因或其片段或其编码的蛋白质或其片段可用于引发体液或细胞免疫应答。
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50.发明申请NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 151P3D4 USEFUL IN TREATMENT AND DETECTION OF CANCER 失效核酸和相关蛋白151P3D4用于治疗和检测癌症公开(公告)号：US20090264381A1
公开(公告)日：2009-10-22
申请号：US11833918
申请日：2007-08-03
申请人： Pia M. Challita-Eid , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Ge Wangmao , Aya Jakobovits
发明人： Pia M. Challita-Eid , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Ge Wangmao , Aya Jakobovits
CPC分类号： C07K14/47 , A61K38/00 , C12N9/78 , Y10T436/25
摘要： A novel gene (designated 151P3D4) and its encoded protein, and variants thereof, are described wherein 151P3D4 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 151P3D4 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 151P3D4 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 151P3D4 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为151P3D4）及其编码的蛋白及其变体，其中151P3D4在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，151P3D4提供了诊断，预后， 癌症的预防和/或治疗靶标。 151P3D4基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与151P3D4反应的抗体或T细胞可用于主动或被动免疫。
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