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公开(公告)号：US11511009B2
公开(公告)日：2022-11-29
申请号：US16631067
申请日：2018-07-12
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： William Spencer Hurst , Steven Clarence Jepson , Grant Anthony Bomgaars , Yuanpang Samuel Ding , Thomas Edward Dudar , Ying-Cheng Lo , Bernd Krause , Mark Edward Pasmore , Michael Joseph Sadowski , Anastasios Hristakos , Joseph Vincent Ranalletta
Abstract: A product bag includes a bladder and an elongated filtration device. The bladder includes opposing first and second film layers defining a product chamber. The first and second film layers are sealed together along a perimeter seal extending along at least a portion of a perimeter of the bladder. The elongated filtration device includes a housing, a filtration membrane disposed in the housing, an inlet adapted for receiving a fluid to be filtered, and an outlet in fluid communication with the product chamber. A majority of the elongated filtration device is embedded between the first and second film layers of the perimeter seal of the bladder to provide for a compact form factor.
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公开(公告)号：US11253849B2
公开(公告)日：2022-02-22
申请号：US16203119
申请日：2018-11-28
Applicant: Baxter International Inc. , Baxter Healthcare SA
IPC: B01J49/53 , A61M1/16 , B01J49/06 , B01J47/024 , B01J47/016 , B01J49/60 , B01J39/02 , B01J39/12 , A61L2/18 , A61L2/26 , B01D15/36 , B01D15/20
Abstract: Methods, sorbent cartridges and cleaning devices are disclosed for refurbishing sorbent materials. In one implementation among multiple implementations, a medical fluid delivery method includes: providing a sorbent cartridge including H+ZP within a casing for a treatment; and after the treatment, refurbishing the H+ZP while maintained within the casing via (i) regenerating the non-disinfected H+ZP by flowing an acid solution through the casing, (ii) rinsing the regenerated H+ZP while maintained within the casing, (iii) disinfecting the regenerated and rinsed H+ZP by flowing a disinfecting agent through the casing, and (iv) rinsing the regenerated and disinfected H+ZP while maintained within the casing. Multiple batch sorbent refurbishing implementations are also disclosed.
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公开(公告)号：US20220008635A1
公开(公告)日：2022-01-13
申请号：US17486390
申请日：2021-09-27
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： Cristian Adolfo Menzel Bueno , Yuanpang Samuel Ding , Rosa Yeh
Abstract: A urea separation apparatus is described herein. In an embodiment, the urea separation apparatus includes a blood compartment that is a part of an extracorporeal circuit fluidly connected to a patient and configured to receive blood of the patient. The apparatus also includes a waste membrane enclosing the blood compartment that is configured to filter waste from the blood. The apparatus further includes a dialysis fluid compartment located on an opposite side of the waste membrane from the blood compartment. The dialysis fluid compartment includes dialysis fluid that absorbs the waste from the waste membrane. The apparatus moreover includes a charged membrane enclosing the dialysis fluid compartment. The charged membrane is configured to filter at least a portion of the waste from the dialysis fluid. Additionally, the apparatus includes a urea compartment that circulates secondary fluid for absorbing the portion of the waste from the charged membrane.
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公开(公告)号：US20210322656A1
公开(公告)日：2021-10-21
申请号：US17363554
申请日：2021-06-30
Applicant: Baxter International Inc. , Baxter Healthcare SA
Inventor： Michael E. Hogard , Donald D. Busby , Robert W. Childers , Yuanpang Samuel Ding , Katherine M. Holian , Mark E. Jablonski , Thomas D. Kelly , Shincy J. Maliekkal , Rodolfo G. Roger , Donald A. Smith , Atif M. Yardimci , Ying-Cheng Lo
Abstract: A system and method for balancing flows of renal replacement fluid is disclosed. The method uses pressure controls and pressure sensing devices to more precisely meter and balance the flow of fresh dialysate and spent dialysate. The balancing system may use one or two balancing devices, such as a balance tube, a tortuous path, or a balance chamber.
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公开(公告)号：US20210308347A1
公开(公告)日：2021-10-07
申请号：US17350754
申请日：2021-06-17
Applicant: Baxter International Inc. , Baxter Healthcare SA
Inventor： Yuanpang Samuel Ding , Cristian Adolfo Menzel Bueno , Rosa Yeh
IPC: A61M1/16 , B01D61/42 , C02F1/469 , C02F1/467 , C02F1/461 , B01D61/44 , C25B3/23 , C25B9/17 , B01D61/46
Abstract: The present disclosure provides devices and methods of using same for cleansing a solution (e.g., a salt or used dialysis solution) of urea via electrooxidation, and more specifically to cleansing a renal therapy solution/dialysis solution of urea via electrooxidation so that the renal therapy solution/dialysis solution can be used or reused for treatment of a patient. In an embodiment, a device for the removal of urea from a fluid having urea to produce a cleansed fluid includes a urea decomposition unit and an electrodialysis unit.
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Patent Agency Ranking
46.发明授权公开(公告)号：US11135344B2
公开(公告)日：2021-10-05
申请号：US16102237
申请日：2018-08-13
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： Jeff White , Ye Chen , Yuanpang Samuel Ding , Joel Titus , Justin Rohde , Shincy Maliekkal , Kevin Cooper
IPC: G01N27/416 , G01N33/00 , G01N27/30 , G01N27/413 , A61M1/16 , C02F1/50 , C02F103/02
Abstract: A dialysis system for determining an amount of total chlorine in a partially purified water sample is disclosed. The system includes a water machine that produces at least partially purified water including an at least partially purified water sample and a dialysis machine that provides a dialysis treatment to a patient. The dialysis machine receives the at least partially purified water from the water machine to prepare dialysis fluid for the dialysis treatment. The system also includes a total chlorine detector configured to receive the at least partially purified water sample, at a first time apply a source voltage to the at least partially purified water sample, and at a second time stop applying the source voltage to the at least partially purified water sample and instead monitor a sensed electrical parameter to determine an amount of total chlorine in the at least partially purified water sample.
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公开(公告)号：US11129929B2
公开(公告)日：2021-09-28
申请号：US16673451
申请日：2019-11-04
Applicant: Baxter International Inc. , Baxter Healthcare SA
Inventor： Cristian Adolfo Menzel Bueno , Yuanpang Samuel Ding , Rosa Yeh
Abstract: Methods and apparatuses for regenerating used dialysis fluid are described herein. In an embodiment, a regenerative dialysis fluid system includes a dialysis unit configured to generate used dialysis fluid including urea, a urea separation unit configured to separate at least a portion of the urea from the used dialysis fluid into a secondary fluid, and a urea removal unit configured to remove at least a portion of the urea from the secondary fluid and return the secondary fluid to the urea separation unit. In an embodiment, the urea separation unit includes a membrane separating a dialysis fluid chamber from a urea chamber, the membrane including at least one of: (i) a positive charge to prevent positive ions from transporting across the membrane; and (ii) a negative charge to prevent negative ions from transporting across the membrane.
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公开(公告)号：US20210290830A1
公开(公告)日：2021-09-23
申请号：US17343190
申请日：2021-06-09
Applicant: Baxter International Inc. , Baxter Healthcare SA
Inventor： Yuanpang Samuel Ding , Cristian Adolfo Menzel Bueno , Rosa Yeh
Abstract: A method of cleaning used dialysis fluid having urea to produce a cleaned dialysis fluid, the method including passing the used dialysis fluid having urea through a combination electrodialysis and urea oxidation cell, the cell including (i) a first set of electrodes for separation of the used dialysis fluid having urea into an acid stream and a basic stream, wherein the first set of electrodes includes an anode and a cathode; (ii) one or more second set of electrodes positioned to contact the basic stream with an electrocatalytic surface for decomposition of urea via electrooxidation, wherein the one or more second set of electrodes includes an anode and a cathode; and (iii) at least one power source to provide the first and second sets of electrodes with an electrical charge to activate the electrocatalytic surface.
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公开(公告)号：US11090421B2
公开(公告)日：2021-08-17
申请号：US16203104
申请日：2018-11-28
Applicant: Baxter International Inc. , Baxter Healthcare SA
Abstract: Methods, sorbent cartridges and cleaning devices are disclosed for refurbishing sorbent materials. In one implementation among multiple implementations, a medical fluid delivery method includes: providing a sorbent cartridge including H+ZP within a casing for a treatment; and after the treatment, refurbishing the H+ZP while maintained within the casing via (i) regenerating the non-disinfected H+ZP by flowing an acid solution through the casing, (ii) rinsing the regenerated H+ZP while maintained within the casing, (iii) disinfecting the regenerated and rinsed H+ZP by flowing a disinfecting agent through the casing, and (iv) rinsing the regenerated and disinfected H+ZP while maintained within the casing. Multiple batch sorbent refubishing implementations are also disclosed.
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公开(公告)号：US11033669B2
公开(公告)日：2021-06-15
申请号：US16535906
申请日：2019-08-08
Applicant: Baxter International Inc. , Baxter Healthcare SA
Inventor： Yuanpang Samuel Ding , Cristian Adolfo Menzel Bueno , Rosa Yeh
IPC: A61M1/16 , B01D61/44 , B01D61/46 , C02F1/469 , C02F1/467 , C02F101/16 , C02F1/461 , B01D61/48 , C25F1/00 , C25F7/00
Abstract: A method of cleaning used dialysis fluid having urea to produce a cleaned dialysis fluid, the method including passing the used dialysis fluid having urea through a combination electrodialysis and urea oxidation cell, the cell including (i) a first set of electrodes for separation of the used dialysis fluid having urea into an acid stream and a basic stream, wherein the first set of electrodes includes an anode and a cathode; (ii) one or more second set of electrodes positioned to contact the basic stream with an electrocatalytic surface for decomposition of urea via electrooxidation, wherein the one or more second set of electrodes includes an anode and a cathode; and (iii) at least one power source to provide the first and second sets of electrodes with an electrical charge to activate the electrocatalytic surface.
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