公开(公告)号：US09795314B2

公开(公告)日：2017-10-24

申请号：US15231709

申请日：2016-08-08

Applicant: Boston Scientific Scimed Inc.

Inventor： Jacob I. Laughner ,  Paul Hultz ,  Shibaji Shome ,  Pramodsingh H. Thakur ,  Scott A. Meyer

IPC: A61B5/04 ,  A61B5/044 ,  A61B5/00 ,  A61B5/042 ,  A61B5/046 ,  A61N1/02 ,  A61B5/0452

CPC classification number: A61B5/04014 ,  A61B5/04012 ,  A61B5/04017 ,  A61B5/0422 ,  A61B5/044 ,  A61B5/04525 ,  A61B5/046 ,  A61B5/6858 ,  A61B5/7239 ,  A61B5/7257 ,  A61B5/7285 ,  A61N1/025

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example method may include a method of identifying an activation time in a cardiac electrical signal. The method may include sensing a cardiac electrical signal, generating an approximation signal based at least in part on one or more parameters of the cardiac electrical signal, identifying a fiducial point on the approximation signal and determining, based at least in part on a timing of the fiducial point in the approximation signal, an activation time in the cardiac electrical signal.

公开(公告)号：US20170143415A1

公开(公告)日：2017-05-25

申请号：US15355745

申请日：2016-11-18

Applicant: Boston Scientific Scimed Inc.

Inventor： Jacob I. Laughner ,  Jason J. Hamann ,  Shibaji Shome ,  Allan C. Shuros ,  Mary M. Byron ,  Paul Hultz ,  Pramodsingh H. Thakur

IPC: A61B18/14 ,  A61M25/01 ,  A61B5/044 ,  A61B5/00 ,  A61B5/0408 ,  A61B5/04

CPC classification number: A61B18/1492 ,  A61B5/04012 ,  A61B5/04085 ,  A61B5/044 ,  A61B5/4836 ,  A61B90/37 ,  A61B2018/00011 ,  A61B2018/00023 ,  A61B2018/00029 ,  A61B2018/0016 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/0072 ,  A61B2018/00791 ,  A61B2018/00839 ,  A61B2018/00875 ,  A61B2018/00886 ,  A61B2018/00892 ,  A61B2034/107 ,  A61B2090/065 ,  A61B2218/002 ,  A61M25/0147

Abstract: A catheter system includes a catheter comprising a tip assembly, the tip assembly having a plurality of electrodes and the plurality of electrodes are configured to measure electrical signals. The system also includes a processing unit configured to: receive a first electrical signal sensed by a first electrode of the plurality of electrodes and a second electrical signal sensed by a second electrode of the plurality of electrodes. A first vector is determined based on the first electrical signal that corresponds to the first electrode. A second vector is determined based on the second electrical signal that corresponds to the second electrode. A resultant vector is determined by summing at least the first vector and the second vector, wherein the resultant vector is indicative of the orientation of the tip assembly.

公开(公告)号：US09649040B2

公开(公告)日：2017-05-16

申请号：US14873800

申请日：2015-10-02

Applicant: Boston Scientific Scimed Inc.

Inventor： Jacob I. Laughner ,  Carlos Alberto Ricci ,  Vladimir V. Kovtun ,  Shibaji Shome ,  Pramodsingh H. Thakur ,  Allan C. Shuros ,  Kevin J. Stalsberg

IPC: A61B5/04 ,  A61B5/0245 ,  A61B5/042 ,  A61B5/046 ,  A61B5/00

CPC classification number: A61B5/0245 ,  A61B5/04014 ,  A61B5/0422 ,  A61B5/046 ,  A61B5/6852 ,  A61B5/7203 ,  A61B5/725 ,  A61B5/7253 ,  A61B5/7257 ,  A61B5/726 ,  A61B2505/05

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example system for mapping the electrical activity of the heart includes a catheter shaft. The catheter shaft includes a plurality of electrodes including a first electrode and a second electrode. The system also includes a processor. The processor is capable of collecting a first signal corresponding to the first electrode and a second signal corresponding to the second electrode. Collecting the first and second signals occurs over a time period. The processor is also capable of generating a first time-frequency distribution corresponding to the first signal, identifying a first dominant frequency value occurring at a first dominant frequency and a first time point, generating a second time-frequency distribution corresponding to the second signal, identifying a second dominant frequency value occurring at a second dominant frequency and a second time point and determining an attraction point.

公开(公告)号：US09579034B2

公开(公告)日：2017-02-28

申请号：US14868182

申请日：2015-09-28

Applicant: Boston Scientific Scimed Inc.

Inventor： Pramodsingh H. Thakur ,  Shantha Arcot-Krishnamurthy ,  Allan C. Shuros ,  Shibaji Shome ,  Barun Maskara ,  Sunipa Saha

IPC: A61B5/0452 ,  A61B5/042 ,  A61B5/04 ,  A61B5/00 ,  A61B5/046 ,  A61B18/14 ,  A61B18/00

CPC classification number: A61B5/04525 ,  A61B5/04012 ,  A61B5/0422 ,  A61B5/046 ,  A61B5/6858 ,  A61B5/7246 ,  A61B18/1492 ,  A61B2018/00357 ,  A61B2018/00577

Abstract: An anatomical mapping system and method includes mapping electrodes configured to detect activation signals of cardiac activity. A processing system is configured to record the detected activation signals and generate a vector field for each sensed activation signal during each instance of the physiological activity. The processing system determines an onset time and alternative onset time candidates, identifies an initial vector field template based on a degree of similarity between the initial vector field and a vector field template from a bank of templates, then determines an optimized onset time for each activation signal based on a degree similarity between the onset time candidates and initial vector field template.

Abstract translation: 解剖映射系统和方法包括配置成检测心脏活动的激活信号的映射电极。 处理系统被配置为记录检测到的激活信号，并且在生理活动的每个实例期间为每个感测到的激活信号生成矢量场。 处理系统确定开始时间和替代的开始时间候选，基于来自一组模板的初始矢量场和矢量场模板之间的相似度来识别初始矢量场模板，然后确定每个激活的优化的开始时间 基于起始时间候选和初始矢量场模板之间的度相似度的信号。

公开(公告)号：US09144391B2

公开(公告)日：2015-09-29

申请号：US14279723

申请日：2014-05-16

Applicant: Boston Scientific Scimed Inc.

Inventor： Pramodsingh H. Thakur ,  Shantha Arcot-Krishnamurthy ,  Allan C. Shuros ,  Shibaji Shome ,  Barun Maskara ,  Sunipa Saha

IPC: A61B5/0452 ,  A61B5/042 ,  A61B5/00 ,  A61B5/046 ,  A61B18/14

CPC classification number: A61B5/04525 ,  A61B5/04012 ,  A61B5/0422 ,  A61B5/046 ,  A61B5/6858 ,  A61B5/7246 ,  A61B18/1492 ,  A61B2018/00357 ,  A61B2018/00577

Abstract: An anatomical mapping system and method includes mapping electrodes configured to detect activation signals of cardiac activity. A processing system is configured to record the detected activation signals and generate a vector field for each sensed activation signal during each instance of the physiological activity. The processing system determines an onset time and alternative onset time candidates, identifies an initial vector field template based on a degree of similarity between the initial vector field and a vector field template from a bank of templates, then determines an optimized onset time for each activation signal based on a degree similarity between the onset time candidates and initial vector field template.

Abstract translation: 解剖映射系统和方法包括配置成检测心脏活动的激活信号的映射电极。 处理系统被配置为记录检测到的激活信号，并且在生理活动的每个实例期间为每个感测到的激活信号生成矢量场。 处理系统确定开始时间和替代的开始时间候选，基于来自一组模板的初始矢量场和矢量场模板之间的相似度来识别初始矢量场模板，然后确定每个激活的优化的开始时间 基于起始时间候选和初始矢量场模板之间的度相似度的信号。

公开(公告)号：US20140343442A1

公开(公告)日：2014-11-20

申请号：US14279723

申请日：2014-05-16

Applicant: Boston Scientific Scimed Inc.

Inventor： Pramodsingh H. Thakur ,  Shantha Arcot-Krishnamurthy ,  Allan C. Shuros ,  Shibaji Shome ,  Barun Maskara ,  Sunipa Saha

IPC: A61B5/0452

CPC classification number: A61B5/04525 ,  A61B5/04012 ,  A61B5/0422 ,  A61B5/046 ,  A61B5/6858 ,  A61B5/7246 ,  A61B18/1492 ,  A61B2018/00357 ,  A61B2018/00577

Abstract: An anatomical mapping system and method includes mapping electrodes configured to detect activation signals of cardiac activity. A processing system is configured to record the detected activation signals and generate a vector field for each sensed activation signal during each instance of the physiological activity. The processing system determines an onset time and alternative onset time candidates, identifies an initial vector field template based on a degree of similarity between the initial vector field and a vector field template from a bank of templates, then determines an optimized onset time for each activation signal based on a degree similarity between the onset time candidates and initial vector field template.

Abstract translation: 解剖映射系统和方法包括配置成检测心脏活动的激活信号的映射电极。 处理系统被配置为记录检测到的激活信号，并且在生理活动的每个实例期间为每个感测到的激活信号生成矢量场。 处理系统确定开始时间和替代的开始时间候选，基于来自一组模板的初始矢量场和矢量场模板之间的相似度来识别初始矢量场模板，然后确定每个激活的优化的开始时间 基于起始时间候选和初始矢量场模板之间的度相似度的信号。

公开(公告)号：US20140187989A1

公开(公告)日：2014-07-03

申请号：US14133242

申请日：2013-12-18

Applicant: Boston Scientific Scimed, Inc.

Inventor： Pramodsingh H. Thakur ,  Barun Maskara ,  Shantha Arcot-Krishnamurthy ,  Shibaji Shome ,  Sunipa Saha ,  Allan C. Shuros

IPC: A61B5/0452

CPC classification number: A61B5/0452 ,  A61B5/04012 ,  A61B5/0422 ,  A61B5/6858 ,  A61B18/1492 ,  A61B2018/00357 ,  A61B2018/00577

Abstract: A method for mapping an anatomical structure includes sensing activation signals of physiological activity with a plurality of electrodes disposed in or near the anatomical structure, each activation signal having an associated cycle length, estimating an action potential duration and diastolic interval for each cycle length, generating a restitution curve based on the estimated action potential duration and diastolic interval from a preceding cycle length, iteratively optimizing each estimated action potential duration and corresponding diastolic interval to maximize a functional relationship between the estimated action potential duration and estimated diastolic interval from preceding cycle length, and generating an action potential duration restitution curve based on the optimized action potential durations and diastolic intervals.

Abstract translation: 用于映射解剖结构的方法包括用设置在解剖结构中或附近的多个电极感测生理活动的激活信号，每个激活信号具有相关联的周期长度，估计每个周期长度的动作电位持续时间和舒张期间隔，产生 基于来自前一周期长度的估计动作电位持续时间和舒张期间隔的恢复曲线，迭代地优化每个估计动作电位持续时间和相应的舒张期间隔，以使估计的动作电位持续时间与前一周期长度的估计的舒张期之间的功能关系最大化， 并基于优化的动作电位持续时间和舒张期间隔产生动作电位持续时间恢复曲线。

公开(公告)号：US20140180151A1

公开(公告)日：2014-06-26

申请号：US14134414

申请日：2013-12-19

Applicant: Boston Scientific Scimed, Inc.

Inventor： Barun Maskara ,  Shantha Arcot-Krishnamurthy ,  Pramodsingh H. Thakur ,  Allan C. Shuros ,  Sunipa Saha ,  Shibaji Shome

IPC: A61B5/04 ,  A61B5/044

CPC classification number: A61B5/044 ,  A61B5/0422 ,  A61B5/6858 ,  A61B5/7203 ,  A61B18/1492 ,  A61B2017/00044 ,  A61B2017/00048 ,  A61B2017/00053 ,  A61B2018/00666 ,  A61B2018/00839

Abstract: A method for mapping an anatomical structure includes sensing activation signals of intrinsic physiological activity with a plurality of electrodes disposed in or near the anatomical structure, identifying at least one of the electrodes not in direct contact with the anatomical structure, and adjusting the activation signals sensed by each of the plurality of electrodes based on the activation signals sensed by the identified at least one of the electrodes not in direct contact with the anatomical structure.

Abstract translation: 用于映射解剖结构的方法包括用设置在解剖结构中或附近的多个电极来感测内在生理活动的激活信号，识别不与解剖结构直接接触的电极中的至少一个，以及调节感测到的激活信号 基于由所识别的不与解剖结构直接接触的至少一个电极感测的激活信号，由多个电极中的每一个电极。

公开(公告)号：US20140107453A1

公开(公告)日：2014-04-17

申请号：US14053573

申请日：2013-10-14

Applicant: Boston Scientific Scimed Inc.

Inventor： Barun Maskara ,  Pramodsingh H. Thakur ,  Shantha Arcot-Krishnamurthy ,  Shibaji Shome ,  Sunipa Saha ,  Allan C. Shuros

IPC: A61B5/06 ,  A61B5/00 ,  A61B18/14 ,  A61B5/042

CPC classification number: A61B5/068 ,  A61B5/0422 ,  A61B5/066 ,  A61B5/4836 ,  A61B5/6858 ,  A61B5/742 ,  A61B5/746 ,  A61B18/1492 ,  A61B2017/00044 ,  A61B2017/00053 ,  A61B2017/00243 ,  A61B2017/003 ,  A61B2018/00267 ,  A61B2018/00351 ,  A61B2018/00839 ,  A61B2018/00898 ,  A61B2018/00904

Abstract: A catheter system includes a plurality of mapping electrodes, an electrode movable relative to the plurality of mapping electrodes, and a guidance system coupled to the plurality of mapping electrodes and the ablation electrode. The guidance system is configured to receive signals associated with intrinsic cardiac activity sensed by the plurality of mapping electrodes and the movable electrode, and to correlate in real-time the intrinsic cardiac activity sensed by the movable electrode with the intrinsic cardiac activity sensed by the plurality of mapping electrodes based on the signals received by the plurality of mapping electrodes and movable electrode to determine a location of the movable electrode with respect to the plurality of mapping electrodes.

Abstract translation: 导管系统包括多个映射电极，相对于多个映射电极可移动的电极，以及耦合到多个映射电极和消融电极的引导系统。 引导系统被配置为接收与由多个映射电极和可移动​​电极感测的固有心脏活动相关联的信号，并且实时地将由可移动电极感测的固有心脏活动与由多个映射电极和可移动​​电极感测的固有心脏活动相关联 基于由多个映射电极和可移动​​电极接收的信号的映射电极，以确定可移动电极相对于多个映射电极的位置。