公开(公告)号：US20190125555A1

公开(公告)日：2019-05-02

申请号：US16173879

申请日：2018-10-29

Applicant: Covidien LP

Inventor： Xiaodong Ma ,  Min-Shyan Sheu ,  Lincoln Eramo ,  John Wainwright ,  Junwei Li

IPC: A61F2/82 ,  A61F2/06 ,  A61L31/16 ,  A61F2/90 ,  A61L31/10 ,  A61L31/02 ,  A61L33/06 ,  A61L31/14 ,  A61L33/00

Abstract: Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.

公开(公告)号：US20150140344A1

公开(公告)日：2015-05-21

申请号：US14085127

申请日：2013-11-20

Applicant: COVIDIEN LP

Inventor： Xiaodong Ma ,  Junwei Li ,  Min-Shyan Sheu ,  Anastasia Righter ,  Ariana Gilmore

IPC: A61L31/10

CPC classification number: A61L31/10 ,  A61L27/34 ,  A61L27/50 ,  A61L27/54 ,  A61L29/085 ,  A61L29/14 ,  A61L29/16 ,  A61L31/14 ,  A61L31/16 ,  A61L2400/18 ,  Y10T428/31663

Abstract: Processes for coating medical devices are provided herein. The processes include contacting a substrate with a sulfur-functional silane and an additional silane. The resulting coating includes a silane layer having improved adherence to the medical device, covering a greater area.

Abstract translation: 本文提供了涂敷医疗器械的方法。 该方法包括使底物与硫官能硅烷和另外的硅烷接触。 所得到的涂层包括具有改进的对医疗装置的附着力的硅烷层，覆盖更大的面积。

公开(公告)号：US12268617B2

公开(公告)日：2025-04-08

申请号：US18581322

申请日：2024-02-19

Applicant: Covidien LP

Inventor： Xiaodong Ma ,  Min-Shyan Sheu ,  Lincoln Eramo ,  John Wainwright ,  Junwei Li

IPC: A61F2/82 ,  A61F2/06 ,  A61F2/90 ,  A61L31/02 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  A61L33/00 ,  A61L33/06 ,  B05D1/18 ,  B05D3/14

Abstract: Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.

公开(公告)号：US12251110B2

公开(公告)日：2025-03-18

申请号：US17938143

申请日：2022-10-05

Applicant: Covidien LP

Inventor： Hoai Nguyen ,  Junwei Li ,  Andyanhdzung Huynh

IPC: A61B17/12 ,  A61B17/00 ,  A61B90/00 ,  B23P19/04

Abstract: Treatment of aneurysms can be improved by delivering an occlusive member (e.g., an expandable braid) to an aneurysm sac in conjunction with an embolic element (e.g., coils, embolic material). A treatment system for such treatment can include an electrolytically corrodible conduit having a proximal portion, a distal portion, and a detachment zone between the proximal portion and the distal portion. An occlusive member having a proximal hub is coupled to the conduit distal portion. The conduit has a lumen configured to pass an embolic element therethrough.

公开(公告)号：US20240390010A1

公开(公告)日：2024-11-28

申请号：US18791050

申请日：2024-07-31

Applicant: Covidien LP

Inventor： Mehdi Matteo Rashidi ,  Junwei Li ,  Belinko K. Matsuura ,  David G. Matsuura ,  Nelson M. Siu

IPC: A61B17/12

Abstract: Devices, systems, and methods for treating aneurysms are disclosed herein. According to some embodiments, the present technology includes a treatment system comprising a delivery shaft, a manipulation shaft slidably positioned within the lumen of the delivery shaft, and an occlusive device configured for implantation within the aneurysm. The occlusive device can comprise a plurality of filaments that are secured to one another at a proximal end of the occlusive device by a cured material. The occlusive device can comprise inner and outer layers of braided filaments, wherein the proximal end region of the inner layer has an exposed portion that extends proximally beyond the proximal end region of the outer layer, and wherein the cured material extends into and fills interstices between the braided filaments at the proximal end regions of the inner and outer layers.

公开(公告)号：US20240341769A1

公开(公告)日：2024-10-17

申请号：US18631785

申请日：2024-04-10

Applicant: Covidien LP

Inventor： Zhijun Bai ,  Junwei Li

IPC: A61B17/12 ,  A61B17/00

CPC classification number: A61B17/12113 ,  A61B17/00234 ,  A61B17/12031 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/12172 ,  A61B17/12177 ,  A61B2017/00292 ,  A61B2017/00477 ,  A61B2017/00778 ,  A61B2017/1205

Abstract: Occlusion devices are disclosed herein. According to some embodiments, the present technology includes a mesh configured to be positioned within an aneurysm cavity, the mesh having a low-profile configuration for delivery through a catheter to the aneurysm cavity and an expanded configuration for implantation in the aneurysm cavity. The mesh can comprise a first portion configured to be positioned over the aneurysm neck and a second portion configured to be positioned between the first portion and a dome of the aneurysm. The mesh can comprise a copper material at the second portion of the mesh, wherein the copper material is configured to promote thrombosis within the aneurysm cavity.

公开(公告)号：US20240075565A1

公开(公告)日：2024-03-07

申请号：US18505645

申请日：2023-11-09

Applicant: Covidien LP

Inventor： Junwei Li ,  Mark Ashby ,  Hoai Nguyen

IPC: B23P19/04 ,  A61B17/12

CPC classification number: B23P19/047 ,  A61B17/12031 ,  A61B17/12113 ,  A61B17/1214 ,  A61B17/12145 ,  A61B17/12172 ,  A61B17/12186 ,  A61B2090/3966

Abstract: Treatment of aneurysms can be improved by delivering an occlusive member (e.g., an expandable braid) to an aneurysm sac in conjunction with an embolic element (e.g., coils, embolic material). A treatment system for such treatment can include an electrolytically corrodible core wire having a proximal portion, a distal portion, and a detachment zone between the proximal portion and the distal portion. An occlusive member having a proximal hub is coupled to the core wire distal portion. A conduit extends along at least a portion of the core wire. The conduit has a lumen configured to pass an embolic element therethrough.

公开(公告)号：US20240050099A1

公开(公告)日：2024-02-15

申请号：US18361760

申请日：2023-07-28

Applicant: Covidien LP

Inventor： Robert A. Pecor ,  Junwei Li ,  Jared Akira Shimizu ,  John M. Wainwright ,  Elijah Klar ,  Taylor S. Dorans ,  Mehdi Matteo Rashidi

IPC: A61B17/12

CPC classification number: A61B17/12172 ,  A61B17/12113 ,  A61B17/12177

Abstract: Systems, methods, and devices for treating vascular defects are disclosed herein. In some embodiments, a device for treating an aneurysm includes a plurality of braided filaments configured to be implanted in an aneurysm cavity.

公开(公告)号：US20240032941A1

公开(公告)日：2024-02-01

申请号：US17815677

申请日：2022-07-28

Applicant: Covidien LP

Inventor： Jared Akira Shimizu ,  Junwei Li ,  Madeleine Roseen ,  Mehdi Matteo Rashidi

IPC: A61B17/12

CPC classification number: A61B17/12186 ,  A61B17/12113 ,  A61B2017/00867

Abstract: A device for treating an intracranial aneurysm in accordance with an embodiment of the present technology includes an elongate conduit body defining an axial lumen through which the conduit body is configured to convey liquid embolic material toward the aneurysm. The conduit body includes a first flexibility zone defining a first average bending stiffness and a first outer diameter. The conduit body further includes a second flexibility zone distal to the first flexibility zone and defining a second average bending stiffness and a second outer diameter. The second average bending stiffness and the second outer diameter are less than the first average bending stiffness and the first outer diameter, respectively. The conduit body also includes a transition zone between the first and second flexibility zones. The transition zone defines a third outer diameter that transitions proximally-to-distally from the first outer diameter to the second outer diameter.

公开(公告)号：US20240032932A1

公开(公告)日：2024-02-01

申请号：US17816380

申请日：2022-07-29

Applicant: Covidien LP

Inventor： Mehdi Matteo Rashidi ,  Junwei Li ,  Belinko K. Matsuura ,  David G. Matsuura ,  Nelson M. Siu

IPC: A61B17/12

CPC classification number: A61B17/12113 ,  A61B17/12027 ,  A61B2017/1205

Abstract: Devices, systems, and methods for treating aneurysms are disclosed herein. According to some embodiments, the present technology includes a treatment system comprising a delivery shaft, a manipulation shaft slidably positioned within the lumen of the delivery shaft, and an occlusive device configured for implantation within the aneurysm. The occlusive device can comprise a plurality of filaments that are secured to one another at a proximal end of the occlusive device by a cured material. The occlusive device can comprise inner and outer layers of braided filaments, wherein the proximal end region of the inner layer has an exposed portion that extends proximally beyond the proximal end region of the outer layer, and wherein the cured material extends into and fills interstices between the braided filaments at the proximal end regions of the inner and outer layers.