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41.发明授权公开(公告)号：US08060184B2
公开(公告)日：2011-11-15
申请号：US11781236
申请日：2007-07-20
IPC分类号： A61B5/05
摘要： A method of navigating the distal end of a medical device through an operating region in a subject's body includes displaying an x-ray image of the operating region, including the distal end of the medical device; determining the location of the distal end of the medical device in a reference frame translatable to the displayed x-ray image; and displaying an enhanced indication of the distal end of the medical device on the x-ray image to facilitate the navigation of the distal end of the device in the operating region.
摘要翻译： 通过主体的操作区域导航医疗装置的远端的方法包括显示包括医疗装置的远端的操作区域的X射线图像; 确定所述医疗装置的远端在参考框架中的位置，所述参考框架可转换成所显示的X射线图像; 以及在x射线图像上显示医疗装置的远端的增强指示，以便于在操作区域中设备的远端的导航。
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42.发明申请SYSTEMS AND METHODS FOR MAKING AND USING AN IMAGING CORE OF AN INTRAVASCULAR ULTRASOUND IMAGING SYSTEM 有权用于制造和使用静脉超声成像系统的成像核心的系统和方法公开(公告)号：US20100249599A1
公开(公告)日：2010-09-30
申请号：US12415768
申请日：2009-03-31
IPC分类号： A61B8/14
CPC分类号： A61B8/4461 , A61B5/02007 , A61B8/12 , A61B8/4281 , A61B8/445
摘要： An imaging assembly for an intravascular ultrasound system includes a catheter, an imaging core, and at least one transducer conductor. The imaging core is insertable into the catheter and extendable from a distal end of the catheter. The imaging core includes a rotatable magnet, a tilted reflective surface, and at least one fixed transducer all disposed in a body. The rotatable magnet is configured and arranged to rotate by a magnetic field generated external to the catheter. The tilted reflective surface rotates with the magnet. The at least one transducer is configured and arranged for transforming applied electrical signals to acoustic signals and also for transforming received echo signals to electrical signals. The at least one transducer conductor is electrically coupled to the at least one transducer and is configured and arranged to extend into the catheter when the imaging core is extended from the catheter.
摘要翻译： 用于血管内超声系统的成像组件包括导管，成像芯和至少一个换能器导体。 成像芯可插入导管中并且可从导管的远端延伸。 成像芯包括可旋转的磁体，倾斜的反射表面以及全部设置在主体中的至少一个固定换能器。 可旋转磁体被构造和布置成通过导管外部产生的磁场旋转。 倾斜的反射表面与磁体一起旋转。 所述至少一个换能器被配置和布置成用于将所施加的电信号变换成声信号，并且还用于将接收的回波信号变换为电信号。 所述至少一个换能器导体电耦合到所述至少一个换能器并且被配置和布置成当所述成像芯从所述导管延伸时延伸到所述导管中。
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公开(公告)号：US07650186B2
公开(公告)日：2010-01-19
申请号：US11075375
申请日：2005-03-07
CPC分类号： A61N1/37223 , A61N1/0587 , A61N1/08 , A61N1/3627 , A61N1/375 , A61N1/3756 , A61N1/3787
摘要： Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrode assemblies that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Also disclosed are various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.
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公开(公告)号：US07647109B2
公开(公告)日：2010-01-12
申请号：US11075376
申请日：2005-03-07
CPC分类号： A61N1/37223 , A61N1/0587 , A61N1/08 , A61N1/3627 , A61N1/375 , A61N1/3756 , A61N1/3787
摘要： Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrode assemblies that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Also disclosed are various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.
摘要翻译： 提供了使用无引线电极来提供起搏治疗的各种构造的系统。 在一个示例中，提供用于心脏心肌的多个部位的系统包括使用经皮，经腔，导管递送系统可植入位于心肌附近的位置的无线起搏电极组件。 还公开了用于递送和植入电极组件的这种系统，无线电极组件和输送导管的各种配置。
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公开(公告)号：US20080319303A1
公开(公告)日：2008-12-25
申请号：US12145419
申请日：2008-06-24
IPC分类号： A61B5/055
摘要： A method of navigating a medical device in an operating region in a subject. The method includes applying a magnetic field to the operating region and changing the magnetic moment of the medical device by selectively changing a physical condition of at least one magnet element in the medical device to change the orientation of the device with respect to the applied magnetic field.
摘要翻译： 一种在受试者的操作区域中导航医疗装置的方法。 该方法包括通过选择性地改变医疗装置中的至少一个磁体元件的物理状态来改变医疗装置的磁矩并改变相对于所施加的磁场的装置的取向来改变操作区域的磁场 。
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公开(公告)号：US07389778B2
公开(公告)日：2008-06-24
申请号：US10834579
申请日：2004-04-29
摘要： A method of navigating a medical device in an operating region in a subject. The method includes applying a magnetic field to the operating region and changing the magnetic moment of the medical device by selectively changing a physical condition of at least one magnet element in the medical device to change the orientation of the device with respect to the applied magnetic field.
摘要翻译： 一种在受试者的操作区域中导航医疗装置的方法。 该方法包括通过选择性地改变医疗装置中的至少一个磁体元件的物理状态来改变医疗装置的磁矩并改变相对于所施加的磁场的装置的取向来改变操作区域的磁场 。
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公开(公告)号：US06662034B2
公开(公告)日：2003-12-09
申请号：US09840311
申请日：2001-04-23
IPC分类号： A61B504
CPC分类号： A61M25/0127 , A61B5/042 , A61B5/06 , A61B5/062 , A61B18/1492 , A61B34/20 , A61B2017/00053 , A61B2017/00084 , A61B2218/002 , A61M25/0054 , A61M25/01 , A61M25/0108 , A61M2025/0004 , A61M2025/0166 , A61M2230/50
摘要： An electrophysiology catheter includes a tube having a proximal end, a distal end, and a lumen therebetween. The tube is preferably comprised of multiple sections of different flexibility, arranged so that the flexibility of the catheter increases from the proximal end to the distal end. There is a first generally hollow electrode member at the distal end. A magnetically responsive element is disposed at least partially in the hollow end electrode, for aligning the distal end of the catheter with an externally applied magnetic field. The hollow end electrode can have openings for delivering irrigating fluid, and/or a sleeve can be provided around the tube to create an annular space for the delivering of irrigating fluid. A temperature sensor can be provided to control the operation of the catheter. A localization coil can also be provided to sense the position and orientation of the catheter.
摘要翻译： 电生理导管包括具有近端，远端和其间的内腔的管。 管优选地由具有不同柔性的多个部分组成，其布置成使得导管的柔性从近端增加到远端。 在远端处有第一大致中空的电极部件。 磁响应元件至少部分地设置在中空端电极中，用于使导管的远端与外部施加的磁场对准。 中空端电极可以具有用于输送冲洗流体的开口，和/或可以在管周围设置套筒，以产生用于输送冲洗流体的环形空间。 可以提供温度传感器来控制导管的操作。 还可以提供定位线圈以感测导管的位置和取向。
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公开(公告)号：US06630879B1
公开(公告)日：2003-10-07
申请号：US09497467
申请日：2000-02-03
IPC分类号： H01F702
CPC分类号： A61B34/73 , A61B1/00158 , A61B34/70 , A61B90/36 , A61B2034/301 , A61B2034/733 , A61B2034/742 , A61M25/0127
摘要： A system for magnetically assisted surgery includes a magnetic support structure, a patient support structure and a magnet having at least four poles attached to the magnetic support structure so that the magnet provides a near-field magnetic field in an operating region of a patient supported by the patient support structure. The magnet is moveable so that the direction of the magnetic field lines in the operating region is adjustable. The magnet may include a pair of essentially semicircular half-segments permanently magnetized and joined in an extremely stable disk configuration. The magnetic field and gradient field provided by the magnet is such that movement of the disk in one plane combined with rotation of the disk is sufficient to orient the magnetic field during surgical use, thereby reducing interference to medical imaging devices needed during surgery. An example of a medical delivery device that may be used for surgery in conjunction with this system is a flexible endoscope or catheter having a series of magnetically permeable rings.
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公开(公告)号：US06582353B1
公开(公告)日：2003-06-24
申请号：US09618253
申请日：2000-07-18
IPC分类号： A61N500
CPC分类号： A61M25/0127 , A61M25/1002 , A61M2025/0177 , A61M2025/1047 , A61M2025/105 , A61M2025/1095 , A61N5/1002 , A61N2005/1003
摘要： An intravascular radiation delivery system including a catheter, a radiation source disposed in an open-ended lumen in the catheter and a closed-ended sheath surrounding the radiation source so as to prevent blood and other fluids from coming into contact with the radiation source. Preferably, the open-ended lumen is centered in the balloon for uniform radiation delivery. The catheter may include a blood perfusion lumen under the balloon or around the balloon. The open-ended lumen in the catheter may have a reduced diameter adjacent the distal end of the catheter to prevent the radiation source from exiting the lumen. Methods of using the radiation delivery system are also disclosed. An alternative method of delivering radiation to a treatment site inside the vasculature of a patient using a gas-filled balloon catheter and a radiation source disposed in the balloon catheter. The treatment site is exposed to radiation, preferably beta radiation, through the gas-filled balloon.
摘要翻译： 一种血管内辐射传播系统，包括导管，设置在导管内的开放式腔内的辐射源和围绕辐射源的封闭护套，以防止血液和其它流体与辐射源接触。 优选地，开口腔在球囊中居中以使辐射均匀。 导管可以包括气囊下方或气球周围的血液灌注腔。 导管中的开口腔可以具有邻近导管远端的减小的直径，以防止辐射源离开内腔。 还公开了使用辐射递送系统的方法。使用设置在球囊导管中的充气球囊导管和辐射源将辐射递送到患者脉管系统内部的治疗部位的替代方法。 通过充气球囊将治疗部位暴露于辐射，优选β辐射。
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公开(公告)号：US06432062B1
公开(公告)日：2002-08-13
申请号：US09813064
申请日：2001-03-20
申请人： Brooke Q. Ren , Roger N. Hastings
发明人： Brooke Q. Ren , Roger N. Hastings
IPC分类号： A61B500
摘要： The inventive method requires advancing a three-dimensional imaging balloon catheter to the site of a lesion to be imaged, inflating or molding the balloon to image the lesion, deflating the balloon, withdrawing the catheter from the body lumen and re-inflating the balloon which reassumes its memorized shape. Stress and thermal mapping of the balloon is then done by direct observation or by numerical analysis of the material strain and color of the re-inflated 3D imaging balloon.
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