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公开(公告)号：US11112377B2
公开(公告)日：2021-09-07
申请号：US15394520
申请日：2016-12-29
Applicant: DexCom, Inc.
Inventor： Shanger Wang , Ted Tang Lee , Jiong Zou
IPC: G01N27/327 , C12Q1/00 , A61B5/00 , A61B5/145 , A61B5/1486 , G01N33/66 , C08G18/08 , C08G18/48 , C08G18/40 , C08G18/38 , C08G18/12 , C08G18/44 , C08G18/75 , C08L39/06 , C08L69/00 , C08L75/04 , A61K31/045 , A61K31/137 , A61K31/46 , A61K31/465 , A61K31/485 , A61K31/515 , A61K31/56 , A61K33/00 , A61K36/185 , A61K38/28 , A61B5/1473 , C12N11/08
Abstract: Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The enzyme layer protects the enzyme and prevents it from leaching from the sensing membrane into a host or deactivating.
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公开(公告)号：US10932709B2
公开(公告)日：2021-03-02
申请号：US14964433
申请日：2015-12-09
Applicant: DexCom, Inc.
Inventor： Peter C. Simpson , Jennifer Blackwell , Sebastian Bohm , Michael J. Estes , Jeff Jackson , Jason Mitchell , Jack Pryor , Daiting Rong , Sean T. Saint , Disha B. Sheth , Shanger Wang
IPC: A61B5/1473 , A61B5/145 , A61B5/00 , A61B17/34 , A61B17/00
Abstract: Sensor devices including dissolvable tissue-piercing tips are provided. The sensor devices can be used in conjunction with dissolvable needles configured for inserting the sensor devices into a host. Hardening agents for strengthening membranes on sensor devices are also provided. Methods of using and fabricating sensor devices are also provided.
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公开(公告)号：US10827955B2
公开(公告)日：2020-11-10
申请号：US15798064
申请日：2017-10-30
Applicant: DexCom, Inc.
Inventor： Peter C. Simpson , Minglian Shi , Sebastian Bohm , John Patrick Majewski , Maria Noel Brown Wells , Leah Morta Edra , Disha B. Sheth , John Michael Gray , Shanger Wang , Ted Tang Lee , Michael L. Moore , Jason Mitchell , Jennifer Blackwell , Neel Narayan Shah , Todd Andrew Newhouse , Jason Halac , Ryan Everett Schoonmaker , Paul V. Neale , Jiong Zou , Sean T. Saint
IPC: A61B5/145 , A61B5/00 , A61B5/1473 , A61B5/1486
Abstract: Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.
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Patent Agency Ranking
公开(公告)号：US20200330006A1
公开(公告)日：2020-10-22
申请号：US16917578
申请日：2020-06-30
Applicant: DexCom, Inc.
Inventor： Peter C. Simpson , Jennifer Blackwell , Sebastian Bohm , Michael J. Estes , Jeff Jackson , Jason Mitchell , Jack Pryor , Daiting Rong , Sean T. Saint , Disha B. Sheth , Shanger Wang
IPC: A61B5/1473 , A61B5/145
Abstract: Sensor devices including dissolvable tissue-piercing tips are provided. The sensor devices can be used in conjunction with dissolvable needles configured for inserting the sensor devices into a host. Hardening agents for strengthening membranes on sensor devices are also provided. Methods of using and fabricating sensor devices are also provided.
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公开(公告)号：US20170191955A1
公开(公告)日：2017-07-06
申请号：US15394694
申请日：2016-12-29
Applicant: DexCom, Inc.
Inventor： Jiong Zou , Robert J. Boock , Andrew Trinin Dennis , Ted Tang Lee , Jeff T. Suri , David Sze , Mark A. Tapsak , Huashi Zhang , Shanger Wang
IPC: G01N27/327 , C08L69/00 , C08L75/04 , C12Q1/00 , C08L39/06
CPC classification number: G01N27/3273 , A61B5/0004 , A61B5/002 , A61B5/14532 , A61B5/14546 , A61B5/1473 , A61B5/1486 , A61B5/14865 , A61B2562/12 , A61K31/045 , A61K31/137 , A61K31/46 , A61K31/465 , A61K31/485 , A61K31/515 , A61K31/56 , A61K33/00 , A61K36/185 , A61K38/28 , C08G18/0828 , C08G18/12 , C08G18/3857 , C08G18/4018 , C08G18/44 , C08G18/4833 , C08G18/755 , C08L39/06 , C08L69/00 , C08L75/04 , C12N11/08 , C12Q1/002 , C12Q1/006 , G01N27/3275 , G01N33/66 , C08G18/3234
Abstract: Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The enzyme layer protects the enzyme and prevents it from leaching from the sensing membrane into a host or deactivating.
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公开(公告)号：US20170188923A1
公开(公告)日：2017-07-06
申请号：US15394748
申请日：2016-12-29
Applicant: DexCom, Inc.
Inventor： Jiong Zou , Robert J. Boock , Andrew Trinin Dennis , Ted Tang Lee , Jeff T. Suri , David Sze , Mark A. Tapsak , Huashi Zhang , Shanger Wang
IPC: A61B5/1486 , A61B5/145 , A61B5/00 , C12Q1/00 , G01N33/66
CPC classification number: G01N27/3273 , A61B5/0004 , A61B5/002 , A61B5/14532 , A61B5/14546 , A61B5/1473 , A61B5/1486 , A61B5/14865 , A61B2562/12 , A61K31/045 , A61K31/137 , A61K31/46 , A61K31/465 , A61K31/485 , A61K31/515 , A61K31/56 , A61K33/00 , A61K36/185 , A61K38/28 , C08G18/0828 , C08G18/12 , C08G18/3857 , C08G18/4018 , C08G18/44 , C08G18/4833 , C08G18/755 , C08L39/06 , C08L69/00 , C08L75/04 , C12N11/08 , C12Q1/002 , C12Q1/006 , G01N27/3275 , G01N33/66 , C08G18/3234
Abstract: Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The enzyme layer protects the enzyme and prevents it from leaching from the sensing membrane into a host or deactivating.
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公开(公告)号：US20160338628A1
公开(公告)日：2016-11-24
申请号：US15160854
申请日：2016-05-20
Applicant: DexCom, Inc.
Inventor： Neel Shah , Jennifer Blackwell , Jonathan Hughes , Ted Tang Lee , Peter C. Simpson , Shanger Wang
IPC: A61B5/145
CPC classification number: A61B17/3468 , A61B5/14503 , A61B5/14532 , A61B5/14865 , A61B2017/3456 , A61B2560/063 , A61M5/3286
Abstract: The present disclosure relates to a needle including a wall structure, a cutting edge and a blunt contour. The needle advantageously can be used to deliver a sensor (such as a glucose or other analyte sensor) through an outer skin layer and into a sensor depth in a less invasive way than prior art needles. The size of the cutting edge is balanced against a portion of the distal wall structure that has blunt contours. Thus, the needle is capable of cutting the more durable outer skin layer (first phase) and then progressively stretching open the cut for further advancement into the subcutaneous layer (second phase). When the needle is sufficiently advanced, it is retracted leaving the sensor in a desired position. Early testing has shown a reduction of “dip and recover” from glucose sensors delivered using the needle.
Abstract translation: 本公开涉及一种包括壁结构，切削刃和钝轮廓的针。 该针有利地可用于将传感器（例如葡萄糖或其它分析物传感器）通过外皮层递送并且以比现有技术针更小侵入的方式传送到传感器深度中。 切割边缘的尺寸与具有钝轮廓的远侧壁结构的一部分相平衡。 因此，针能够切割更耐用的外皮层（第一相），然后逐渐拉伸开口以进一步前进到皮下层（第二阶段）。 当针足够前进时，它被缩回离开传感器到期望的位置。 早期测试显示，使用针头传送的葡萄糖传感器可以减少“沾污和恢复”。
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公开(公告)号：US20160113556A1
公开(公告)日：2016-04-28
申请号：US14964433
申请日：2015-12-09
Applicant: DexCom, Inc.
Inventor： Peter C. Simpson , Jennifer Blackwell , Sebastian Bohm , Michael J. Estes , Jeff Jackson , Jason Mitchell , Jack Pryor , Daiting Rong , Sean T. Saint , Disha B. Sheth , Shanger Wang
IPC: A61B5/1473 , A61B5/00 , A61B17/34 , A61B5/145
CPC classification number: A61B5/1473 , A61B5/14503 , A61B5/14532 , A61B5/4839 , A61B5/6848 , A61B17/3468 , A61B2017/00004
Abstract: Sensor devices including dissolvable tissue-piercing tips are provided. The sensor devices can be used in conjunction with dissolvable needles configured for inserting the sensor devices into a host. Hardening agents for strengthening membranes on sensor devices are also provided. Methods of using and fabricating sensor devices are also provided.
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