Methods and compositions for treatment of ion imbalances
    41.
    发明授权
    Methods and compositions for treatment of ion imbalances 有权
    用于治疗离子失衡的方法和组合物

    公开(公告)号:US08147873B2

    公开(公告)日:2012-04-03

    申请号:US12055457

    申请日:2008-03-26

    IPC分类号: A61K9/14 A61K9/50

    CPC分类号: A61K31/74

    摘要: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising sodium-binding polymers and pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hypertension, chronic heart failure, end stage renal disease, liver cirrhosis, chronic renal insufficiency, fluid overload, or sodium overload.

    摘要翻译: 本发明提供了用于治疗离子失衡的方法和组合物。 特别地,本发明提供了包含钠结合聚合物及其药物组合物的组合物。 本文公开了用于治疗和/或预防益处的聚合物和药物组合物的使用方法。 这些方法的实例包括治疗高血压,慢性心力衰竭,终末期肾病,肝硬化,慢性肾功能不全,流体过载或钠过载。

    Functionalized matrices for dispersion of nanostructures
    44.
    发明授权
    Functionalized matrices for dispersion of nanostructures 有权
    用于纳米结构分散的功能化基质

    公开(公告)号:US08283412B2

    公开(公告)日:2012-10-09

    申请号:US12799813

    申请日:2010-04-29

    IPC分类号: C08L83/04 C08G77/26

    摘要: Matrixes doped with semiconductor nanocrystals are provided. In certain embodiments, the semiconductor nanocrystals have a size and composition such that they absorb or emit light at particular wavelengths. The nanocrystals can comprise ligands that allow for mixing with various matrix materials, including polymers, such that a minimal portion of light is scattered by the matrixes. The matrixes are optionally formed from the ligands. The matrixes of the present invention can also be utilized in refractive index matching applications. In other embodiments, semiconductor nanocrystals are embedded within matrixes to form a nanocrystal density gradient, thereby creating an effective refractive index gradient. The matrixes of the present invention can also be used as filters and antireflective coatings on optical devices and as down-converting layers. Processes for producing matrixes comprising semiconductor nanocrystals are also provided. Nanostructures having high quantum efficiency, small size, and/or a narrow size distribution are also described, as are methods of producing indium phosphide nanostructures and core-shell nanostructures with Group II-VI shells.

    摘要翻译: 提供掺杂半导体纳米晶体的矩阵。 在某些实施方案中,半导体纳米晶体具有使其吸收或发射特定波长的光的尺寸和组成。 纳米晶体可以包括允许与各种基质材料(包括聚合物)混合的配体,使得最小部分的光被基质散射。 该基质任选地由配体形成。 本发明的基质也可用于折射率匹配应用。 在其它实施例中,将半导体纳米晶体嵌入在基质内以形成纳米晶体密度梯度,从而产生有效的折射率梯度。 本发明的基质也可以用作光学器件上的滤光片和抗反射涂层以及下变换层。 还提供了用于生产包含半导体纳米晶体的基质的方法。 还描述了具有高量子效率,小尺寸和/或窄尺寸分布的纳米结构,以及生产具有II-VI族壳的磷化铟纳米结构和核 - 壳纳米结构的方法。