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公开(公告)号：US20220323210A1
公开(公告)日：2022-10-13
申请号：US17851328
申请日：2022-06-28
Applicant: Edwards Lifesciences Corporation
Inventor： Noam Nir , Elena Sherman , Tamir S. Levi , Michael Bukin
Abstract: Assembly methods for installing a leaflet assembly to an expandable frame of a prosthetic heart valve are described. The leaflet assembly comprises a plurality of leaflets coupled together at adjacent tabs, which form respective commissure tab assemblies. The commissure tab assemblies are inserted into corresponding windows of support members of the expandable frame. One or more wedge members are inserted into the commissure tab assembly, e.g., between the adjacent tabs or with the adjacent tabs therebetween, to restrain radial motion of the commissure tab assembly with respect to the window. The window can be a closed window, and the wedge member insertion can be after the commissure tab assembly is inserted into the window. Alternatively, the window can be an open window or channel, and the wedge member insertion can be before the commissure tab assembly is installed in the window.
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公开(公告)号：US20210393398A1
公开(公告)日：2021-12-23
申请号：US17466331
申请日：2021-09-03
Applicant: Edwards Lifesciences Corporation
Inventor： Tamir S. Levi , Noam Nir , Michael Bukin , David Maimon , Haim Yushtein
IPC: A61F2/24
Abstract: A prosthetic heart valve includes an annular frame that is radially collapsible and radially expandable, a plurality of leaflets situated within the frame, each leaflet having opposing commissure tab portions on opposite sides of the leaflet, each commissure tab portion paired with an adjacent commissure tab portion of an adjacent leaflet to form at least one commissure, and a plurality of post members mounted on an interior surface of the frame. The at least one commissure includes a commissure attachment assembly including a support member disposed at least partially around the commissure tab portions and the commissure tab portions are folded around the support member. The commissure attachment assembly is secured to a first post member of the plurality of post members such that the commissure tab portions are positioned between the first post member and the support member.
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公开(公告)号：US20190021834A1
公开(公告)日：2019-01-24
申请号：US16036190
申请日：2018-07-16
Applicant: Edwards Lifesciences Corporation
Inventor： Noam Nir , Carmel Peleg , Tomer Saar , Alexander Barash , David Maimon
Abstract: Disclosed herein is a storage container for an expandable prosthetic heart valve that crimps the valve upon opening the container and removal of the valve from the container. The container includes a housing sized to receive the heart valve in its expanded configuration and a crimping mechanism. The crimping mechanism is incorporated into the container and engages the heart valve so as to operably convert the heart valve from its expanded configuration to its smaller crimped configuration upon opening the container and removing the valve.
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公开(公告)号：US10179043B2
公开(公告)日：2019-01-15
申请号：US15425029
申请日：2017-02-06
Applicant: Edwards Lifesciences Corporation
Inventor： Hanoch Cohen-Tzemach , Tamir S. Levi , Noam Nir , Bella Felsen
IPC: A61F2/24
Abstract: Embodiments of a prosthetic heart valve are disclosed. An implantable prosthetic valve may be radially collapsible to a collapsed configuration and radially expandable to an expanded configuration. The prosthetic valve may comprise an annular frame, a leaflet structure positioned within the frame and a plurality of outer skirts positioned around an outer surface of the frame, each outer skirt comprising an inflow edge secured to the frame and an outflow edge secured at intervals to the frame. The plurality of outer skirts may include a first outer skirt and a second outer skirt, wherein in the expanded configuration the first and second outer skirts include openings unsecured to the frame between the intervals. The inflow edge of the first annular outer skirt may be secured to the frame with sutures including radiopaque material. The first annular outer skirt may include radiopaque dye.
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公开(公告)号：US20180344456A1
公开(公告)日：2018-12-06
申请号：US15995528
申请日：2018-06-01
Applicant: Edwards Lifesciences Corporation
Inventor： Alexander Barash , Yair A. Neumann , Tomer Saar , Ziv Yohanan , Noam Nir
IPC: A61F2/24
Abstract: In one embodiment, a prosthetic valve can comprise a radially expandable and compressible frame, which can include a plurality of struts which are pivotally joined together without requiring individual rivets. In some embodiments, the struts are interwoven, and can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In another embodiment, the frame comprises a plurality of inner struts and outer struts which are connected by a plurality of chains of interconnected rivets, avoiding the need to provide individual rivets at each junction between struts. In still another embodiment, separate hinges are provided to interconnect the struts. In still another embodiment, separate flanged rivets are provided to connect the struts.
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Patent Agency Ranking
公开(公告)号：US20170128205A1
公开(公告)日：2017-05-11
申请号：US15344163
申请日：2016-11-04
Applicant: Edwards Lifesciences Corporation
Inventor： Ilan Tamir , Noam Nir , Boaz Manash , David Maimon , Oren Cohen
IPC: A61F2/24
CPC classification number: A61F2/2436 , A61F2/2439
Abstract: Disclosed herein are embodiments of delivery capsules for delivering prosthetic implants around the relatively tight bends of a catheter. In particular, disclosed herein are delivery capsules including a tubular layer for holding the heart valve, a frame enclosing the tubular layer and an elongate element coupled to the frame for allowing the tubular layer and frame to expand. For example, the frame may be biased to expand and withdrawal of the elongate element from openings in the frame can release the frame to expand into a larger diameter. Another embodiment includes a helical wire wrapped around the capsule for easy delivery through bends and a second helical wire that is advanced between windings of the first helical wire to selectively stiffen the capsule for withdrawal. Other embodiments include sock-like capsules that can be crumpled into shorter lengths by pulling a pull line attached to the capsule.
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公开(公告)号：US20250134656A1
公开(公告)日：2025-05-01
申请号：US19008936
申请日：2025-01-03
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Noam Nir , Michael Bukin
Abstract: In some embodiments, a prosthetic valve assembly includes an annular frame being radially expandable and compressible between a radially compressed configuration and a radially expanded configuration, and a valvular structure comprising a plurality of leaflets mounted inside the annular frame. The annular frame includes a plurality of posts. Each post has a pair of commissure attachment members extending away from the post. Each pair of commissure tabs is attached to a corresponding pair of the commissure attachment members.
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公开(公告)号：US20240277473A1
公开(公告)日：2024-08-22
申请号：US18645284
申请日：2024-04-24
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Michael Bukin , Nikolai Gurovich , Anatoly Dvorsky , Eran Grosu , Noam Nir , Joseph Mordechai Leichner
IPC: A61F2/24
CPC classification number: A61F2/243 , A61F2/2418 , A61F2250/001
Abstract: A prosthetic device, such as a prosthetic heart valve, can include a radially compressible and expandable frame and a screw actuator that is coupled to the frame and configured to be rotated to radially expand the frame from a radially compressed state to a first radially expanded state. The frame includes an over-expansion structure that is configured to allow relative sliding movement between the screw actuator and the frame in a longitudinal direction to permit the frame to radially expand from the first radially expanded state to a second radially expanded state when an external expansion force applied to the prosthetic heart valve exceeds a predetermined force.
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公开(公告)号：US20230310150A1
公开(公告)日：2023-10-05
申请号：US18207822
申请日：2023-06-09
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Alexander Barash , Yair A. Neumann , Tomer Saar , Ziv Yohanan , Noam Nir
CPC classification number: A61F2/2418 , A61F2/243 , A61F2/2439 , A61F2/844 , A61F2002/9511 , A61F2/9517 , A61F2/2436
Abstract: In one embodiment, a method of assembling a prosthetic valve can comprise forming a radially expandable and compressible frame by pivotally joining together a plurality of struts without requiring individual rivets. In some embodiments, the frame is formed by interweaving the struts, which can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In other embodiments, separate hinges are provided to interconnect the struts. In still other embodiments, separate flanged rivets are provided to connect the struts.
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公开(公告)号：US20230285144A1
公开(公告)日：2023-09-14
申请号：US18015707
申请日：2021-07-08
Applicant: Edwards Lifesciences Corporation
Inventor： Haim Yushtein , Anatoly Dvorsky , David Maimon , Noam Nir , Alon Ben-Yosef
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/243 , A61F2/2439 , A61F2220/0091 , A61F2250/001 , A61F2250/0029
Abstract: A prosthetic device, such as a prosthetic heart valve, can include a frame that is radially expandable and compressible between a radially compressed state and a radially expanded state. In some examples, the prosthetic device can include locking mechanisms that are configured to hold the prosthetic device in a radially expanded state. In some examples, the locking mechanisms can be integrated into the frame of the prosthetic device.
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